LOCUS       NM_001108963            3733 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus solute carrier family 2 member 10 (Slc2a10),
            mRNA.
ACCESSION   NM_001108963 XM_001072818 XM_345471
VERSION     NM_001108963.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3733)
  AUTHORS   Nemeth CE, Marcolongo P, Gamberucci A, Fulceri R, Benedetti A,
            Zoppi N, Ritelli M, Chiarelli N, Colombi M, Willaert A, Callewaert
            BL, Coucke PJ, Grof P, Nagy SK, Meszaros T, Banhegyi G and
            Margittai E.
  TITLE     Glucose transporter type 10-lacking in arterial tortuosity
            syndrome-facilitates dehydroascorbic acid transport
  JOURNAL   FEBS Lett 590 (11), 1630-1640 (2016)
   PUBMED   27153185
REFERENCE   2  (bases 1 to 3733)
  AUTHORS   Zoppi N, Chiarelli N, Cinquina V, Ritelli M and Colombi M.
  TITLE     GLUT10 deficiency leads to oxidative stress and non-canonical
            alphavbeta3 integrin-mediated TGFbeta signalling associated with
            extracellular matrix disarray in arterial tortuosity syndrome skin
            fibroblasts
  JOURNAL   Hum Mol Genet 24 (23), 6769-6787 (2015)
   PUBMED   26376865
REFERENCE   3  (bases 1 to 3733)
  AUTHORS   Faiyaz-Ul-Haque,M., Zaidi,S.H., Wahab,A.A., Eltohami,A.,
            Al-Mureikhi,M.S., Al-Thani,G., Peltekova,V.D., Tsui,L.C. and
            Teebi,A.S.
  TITLE     Identification of a p.Ser81Arg encoding mutation in SLC2A10 gene of
            arterial tortuosity syndrome patients from 10 Qatari families
  JOURNAL   Clin Genet 74 (2), 189-193 (2008)
   PUBMED   18565096
REFERENCE   4  (bases 1 to 3733)
  AUTHORS   Coucke PJ, Willaert A, Wessels MW, Callewaert B, Zoppi N, De Backer
            J, Fox JE, Mancini GM, Kambouris M, Gardella R, Facchetti F,
            Willems PJ, Forsyth R, Dietz HC, Barlati S, Colombi M, Loeys B and
            De Paepe A.
  TITLE     Mutations in the facilitative glucose transporter GLUT10 alter
            angiogenesis and cause arterial tortuosity syndrome
  JOURNAL   Nat Genet 38 (4), 452-457 (2006)
   PUBMED   16550171
REFERENCE   5  (bases 1 to 3733)
  AUTHORS   Dawson PA, Mychaleckyj JC, Fossey SC, Mihic SJ, Craddock AL and
            Bowden DW.
  TITLE     Sequence and functional analysis of GLUT10: a glucose transporter
            in the Type 2 diabetes-linked region of chromosome 20q12-13.1
  JOURNAL   Mol Genet Metab 74 (1-2), 186-199 (2001)
   PUBMED   11592815
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474005.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_345471.3, XM_001072818.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMN06621351 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3733
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..3733
                     /gene="Slc2a10"
                     /note="solute carrier family 2 member 10"
                     /db_xref="GeneID:366251"
                     /db_xref="RGD:1306552"
     exon            1..119
                     /gene="Slc2a10"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..1726
                     /gene="Slc2a10"
                     /note="solute carrier family 2 (facilitated glucose
                     transporter), member 10"
                     /codon_start=1
                     /product="solute carrier family 2, facilitated glucose
                     transporter member 10"
                     /protein_id="NP_001102433.1"
                     /db_xref="GeneID:366251"
                     /db_xref="RGD:1306552"
                     /translation="MGLGPTVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFRLSC
                     LEQELLVGSLLLGAFLASLVGGFLIDCYGRRRAILGSNVVLLAGSLILGLAGSLPWLL
                     LGRSSVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEVGITVGILFSYGLNYVLAGS
                     PWGWRHMFGWAAAPALLQSLSLFFLPAGAEGTAARQDLIPLQGGETSKLGLVKAQYTF
                     LDLFRAQDGMWSRTVVGLGLVLFQQLTGQPNVLYYASTIFRSVGFHGGSSAVLASVGL
                     GTVKVVATLIATGLVDRVGRRALLLSGCALMALSVSGIGLVSFAVSLDSGPSCLATSN
                     TSQQVDLPQTPGLLVRTSLPPVLHTSGDQGQPVRSVTERPIHPVITASLGPALNIDSS
                     VPTSPIPEHTLLCWSALVCMMVYVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCSSF
                     NWAANLFISLSFLDLIGAIGLAWTFLLYGLTAVLGLAFIYLLVPETKGQSLAEIEQQF
                     QMRRFPLSFGHRQHSGIQYRRLEVSSAS"
     exon            120..1391
                     /gene="Slc2a10"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1514
                     /gene="Slc2a10"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1650
                     /gene="Slc2a10"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..3733
                     /gene="Slc2a10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagggcgcag gccctagctc tggggaaagt ttatccgcca cggctacagc ggggatttga
       61 ccaggacgtg cagggcccag agcccagccc gcctgcccag cgctactcgc tagctatggg
      121 ccttggcccg actgtcctcc cgctctgtgc ctccgtgtct ctgctggggg gcctgacctt
      181 tggctatgag ctggctgtca tatccggtgc cctcctacca ctgcagctgg acttcaggct
      241 gagctgcctg gaacaggagc tcctggtggg cagcctgctc ttgggtgctt tcctcgcctc
      301 ccttgtcggg ggcttcctca ttgactgcta tggcaggaga cgagccatct tggggagcaa
      361 tgtggtgctg ctggctggca gcctgattct gggtctggcc ggctcccttc cctggctgct
      421 cctgggccgc tcatccgtgg gcttcgccat ctctctgtct tccatggctt gctgtatcta
      481 cgtgtcagag ttggtggggc cgaggcagcg gggcgtgctg gtatccctct acgaggtggg
      541 catcactgtg ggcatcctgt tctcctatgg cctcaactac gtcctggctg gcagcccttg
      601 gggctggagg cacatgtttg gctgggcggc tgcacccgct cttctacagt cactcagcct
      661 cttctttctc cctgctggtg cagaaggcac agcagcccgc caagacctca tcccactcca
      721 gggaggggag accagcaaac tgggcctggt gaaggcacag tacacctttc tggacctctt
      781 cagggctcag gacggcatgt ggagccgcac agtagtgggg ctggggctag tgttgttcca
      841 gcagctaaca gggcaaccca acgtgttata ttatgcctcc accatatttc gctctgttgg
      901 cttccatggg ggctcctcag ctgtgctggc ttctgtgggg cttggtactg tgaaggtggt
      961 tgccaccctg atcgccacgg ggctggtgga ccgtgtaggc cgtagagccc ttctactctc
     1021 tggttgtgct ctcatggcct tgtctgtcag tggcataggc ctagttagct ttgctgtgtc
     1081 cctggattct ggccccagct gcctggccac atccaacacc agccagcagg tggacctgcc
     1141 tcaaaccccg ggtctgcttg tgcgtacatc tctaccacca gtgctacaca ccagtggaga
     1201 tcaaggacaa ccagtccggt cagtcactga gagacccatc catccagtca tcacagcgtc
     1261 cctgggacca gctctgaata ttgactcctc agtgcccact agtcccatcc cggagcatac
     1321 cctcctctgc tggtctgcac tggtttgcat gatggtctac gtgagcgcct tctcctttgg
     1381 gtttggacca gtaacctggc tggtcctcag tgagatctat ccggtggaga tccgagggcg
     1441 agccttcgcc ttctgcagca gcttcaactg ggcagctaac ctcttcatca gcctgtcctt
     1501 cctcgacctt atcggtgcca tcggcttggc ctggaccttc ctgctgtatg ggctgaccgc
     1561 tgtccttggc ttagctttca tctacttact cgttcctgaa acaaaaggac agtcgctggc
     1621 tgaaatagag cagcagtttc agatgaggag gttccctctg agctttggcc acaggcagca
     1681 cagcggtatt cagtaccgcc gcctggaggt ctcctcagcc tcctgagggg tccgtctgct
     1741 tggaagatgc tgggacattg gtttctgcag cccagctcca gatccctgcc tgctggggcc
     1801 tggaactcat gatctagaat tccttctgta gagagccctg ctccagaggc tgcctcttac
     1861 cagggagaga gatgagcacc aaactctccc ttttgagtgt gagacttcaa gggctctgga
     1921 agctctagtt ccgtgcctca gtttccctgt ggagttggct tgtctgccat gtttataagg
     1981 acatggtgtg gtgtgttcac caagtgcttc tcagaagacc tgggaaggag gtgtccccta
     2041 ccaccagccc agaccagcag aggctgagtc tccaccttcc tcatcccctt gccggggtct
     2101 tgtgatccag aacccgtatt caccaccgcc ttcctcttgc ccaagatatt tatcaggtgc
     2161 tgggactctg actggggaca gcaggctgta accaagatgg ctttatgacc ctgcctcagc
     2221 ttccccctga aaccctgtgt cttacggact aggctgctcc taagatccct tctccacaag
     2281 gacggaagtc tcagagcagg gacataataa gcactcggtg agggccccca tcaaatggct
     2341 ctggggacag gagctttttt tttaacagag tgcatctcag ttccagagtc tagcactctg
     2401 gaacgtaaga gctgaaccac gacacgtgac aagcactagg aaccccacgg ttcccgggtt
     2461 tcagcaaggg gctttgaatg aaggaagggt ttagagggac tcatccatgt gttggctgtt
     2521 gtggcttcta ctttgggtgc taatgactcc ctacggcctc agtttatttg tctgcagaat
     2581 gggcacagtc gtacccctca ggatatcttg acttacccca tctctcccag gagggtcttc
     2641 agtgaggtcc tgggggcttc cgctcaccct gttacacagg gctcttcttc agggcattgt
     2701 aaaaagggtc agtcagctgg agacaagcaa gtggctcaag tcagagttgc cataaggagg
     2761 acgtcagtaa catagtttgt tcctggatac tgggtagctg acctcaccag cactgtcagc
     2821 caagcctgat ctggtgacca cactctctag atatttcatt catgaccaat ggcgtgctgg
     2881 attaagcctg tgctggctcc ccagagccga ctcccacaca gtcaagattt ctacagacag
     2941 ggtgctaagc actgcaatcg ttgtgaaagt gttctagttg atagtaaatg tcattatagt
     3001 agtcagtgac atcatcactg cctacgtgat ggtgcatgcc tgtaatccga gcactcgggg
     3061 cttaaggatt gagtgttgta gaccagcctg gcttcaaact gaaaccttgt ccaaacaaat
     3121 cgataggaga atacaaaacc tgagcccgcg ttgccacctc ctaaggtctc tgccggcttc
     3181 tccctcctcc gtgctgccgg gatgtcttca tgtaggtctg acagagacag aggcaggtat
     3241 atgttttcca cttaagcact cagtgtcttc acaatgaacc aaccctgggt gagcctctgc
     3301 attccagagg ttagggaaca ctgtagacca gggcttggtt tatcgtttgt tttttttctg
     3361 gagttaggaa ctgctgggtc aagtgttaat tatataaatt aaactcaaag aagcctcctg
     3421 ttgtagctgg tatgttgaaa acatcgcaga aaacggtgtg tgtgtgtgtg tgtgtgtgtg
     3481 tgtgtgtgtg tgtgtgtgag agagagagag agagagagag aatattctat tggtcagttc
     3541 agcagacact tgctctttgc ctcaatggag ggaagggccc tgatacgcac gcatcttacc
     3601 ttctggaatg tgtgtctgtc acctagcccc aactgcacgc tgactgctta cagaatgctc
     3661 ttcagacgaa atgttttctc acacaaagat gtgtcattta acagtgtgtt ttgaaataaa
     3721 ttatcttgaa gac
//
