LOCUS       NM_080908               2176 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus solute carrier family 28 member 3 (Slc28a3),
            mRNA.
ACCESSION   NM_080908 XM_008771422
VERSION     NM_080908.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2176)
  AUTHORS   Godoy,V., Banales,J.M., Medina,J.F. and Pastor-Anglada,M.
  TITLE     Functional crosstalk between the adenosine transporter CNT3 and
            purinergic receptors in the biliary epithelia
  JOURNAL   J Hepatol 61 (6), 1337-1343 (2014)
   PUBMED   25034758
  REMARK    GeneRIF: There is functional crosstalk between the adenosine
            transporter CNT3 and purinergic receptors in the cholangiocytes in
            rats.
REFERENCE   2  (bases 1 to 2176)
  AUTHORS   Nagase,K., Tomi,M., Tachikawa,M. and Hosoya,K.
  TITLE     Functional and molecular characterization of adenosine transport at
            the rat inner blood-retinal barrier
  JOURNAL   Biochim Biophys Acta 1758 (1), 13-19 (2006)
   PUBMED   16487924
REFERENCE   3  (bases 1 to 2176)
  AUTHORS   Rodriguez-Mulero,S., Errasti-Murugarren,E., Ballarin,J., Felipe,A.,
            Doucet,A., Casado,F.J. and Pastor-Anglada,M.
  TITLE     Expression of concentrative nucleoside transporters SLC28 (CNT1,
            CNT2, and CNT3) along the rat nephron: effect of diabetes
  JOURNAL   Kidney Int 68 (2), 665-672 (2005)
   PUBMED   16014043
  REMARK    GeneRIF: Diabetes increased CNT1 and CNT3 expression in the
            glomerulus and insulin treatment decreased it.
REFERENCE   4  (bases 1 to 2176)
  AUTHORS   Gray,J.H., Owen,R.P. and Giacomini,K.M.
  TITLE     The concentrative nucleoside transporter family, SLC28
  JOURNAL   Pflugers Arch 447 (5), 728-734 (2004)
   PUBMED   12856181
  REMARK    Review article
REFERENCE   5  (bases 1 to 2176)
  AUTHORS   Ritzel,M.W., Ng,A.M., Yao,S.Y., Graham,K., Loewen,S.K., Smith,K.M.,
            Ritzel,R.G., Mowles,D.A., Carpenter,P., Chen,X.Z., Karpinski,E.,
            Hyde,R.J., Baldwin,S.A., Cass,C.E. and Young,J.D.
  TITLE     Molecular identification and characterization of novel human and
            mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3
            and mCNT3) broadly selective for purine and pyrimidine nucleosides
            (system cib)
  JOURNAL   J Biol Chem 276 (4), 2914-2927 (2001)
   PUBMED   11032837
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On or before Mar 10, 2021 this sequence version replaced
            XM_008771422.3, NM_080908.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY059414.1, SRR26643297.47882.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-171               JAXUCZ010000017.1  6068069-6068239
            172-261             JAXUCZ010000017.1  6089979-6090068
            262-347             JAXUCZ010000017.1  6091483-6091568
            348-439             JAXUCZ010000017.1  6093710-6093801
            440-629             JAXUCZ010000017.1  6095762-6095951
            630-774             JAXUCZ010000017.1  6098256-6098400
            775-888             JAXUCZ010000017.1  6100796-6100909
            889-966             JAXUCZ010000017.1  6101548-6101625
            967-1047            JAXUCZ010000017.1  6102770-6102850
            1048-1128           JAXUCZ010000017.1  6103471-6103551
            1129-1254           JAXUCZ010000017.1  6105601-6105726
            1255-1385           JAXUCZ010000017.1  6107898-6108028
            1386-1554           JAXUCZ010000017.1  6110138-6110306
            1555-1752           JAXUCZ010000017.1  6111068-6111265
            1753-1834           JAXUCZ010000017.1  6115146-6115227
            1835-1933           JAXUCZ010000017.1  6115733-6115831
            1934-2045           JAXUCZ010000017.1  6116063-6116174
            2046-2176           JAXUCZ010000017.1  6117978-6118108
FEATURES             Location/Qualifiers
     source          1..2176
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..2176
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /note="solute carrier family 28 member 3"
                     /db_xref="GeneID:140944"
                     /db_xref="RGD:621224"
     exon            1..171
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..2172
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /note="CNT 3; rCNT3; concentrative Na(+)-nucleoside
                     cotransporter 3; solute carrier family 28 (sodium-coupled
                     nucleoside transporter), member 3; solute carrier family
                     28 (concentrative nucleoside transporter), member 3"
                     /codon_start=1
                     /product="solute carrier family 28 member 3"
                     /protein_id="NP_543184.2"
                     /db_xref="GeneID:140944"
                     /db_xref="RGD:621224"
                     /translation="MSRSDPDPGKNSEPSKSKMSLELRPTAPSDQGRLNEAFQDEDLE
                     EQNAPGNSTVRSRVVQSGEQGRAKQDDRQITIEQEPLGPKEGTEEESEDERQKGFLER
                     KYDTVCEFCRKHRVILQHTIWAVLLTGFLALVIAACALNFHRALPLFVITLVTIFFVV
                     WDRLMAKYEQRIDDVLSPGKRLLERHWFWLKWVVWCSLILAVILWLALDTARLGQQQL
                     ISFGGLVMYIVLLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGKQ
                     VQTFLGYTDAGAQFVFGEKYTDHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGW
                     LMLVTMGSSPIESVVAAGNIFVGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSV
                     LGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKNAMKMENGDSRNLL
                     EAATQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFDYPQLSFELICSYIFM
                     PFSFMMGVDWQDSFMVAKLIGYKTFFNEFVAYEHLSKFINLRKAAGPKFVNGVQQYMS
                     IRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTAC
                     IAGMLSDTPVAINCHHVLESSKVLSNTTEVASCCQDLFNSTVARGPNDVLPGGNFSLY
                     TLKSCCNLLKPPTLNCGWIPNIP"
     exon            172..261
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            262..347
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            348..439
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            440..629
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            630..774
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            775..888
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            889..966
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1047
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1128
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1254
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1385
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1554
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1555..1752
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1834
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..1933
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1934..2045
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
     exon            2046..2176
                     /gene="Slc28a3"
                     /gene_synonym="Cnt3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaggtggcc ctctgacaga gcggaggtgg tgcttgctct ctctcagcca gaggatgtcc
       61 aggtcagacc cagacccggg aaagaattcg gagcccagta agagcaagat gagcctggag
      121 ctgaggccaa cagcccccag cgaccagggc cgcctcaacg aagccttcca ggatgaagac
      181 ctggaagagc agaacgctcc aggaaacagc acagtcagga gcagagttgt acagagtggg
      241 gagcaaggac gggccaaaca ggacgacagg cagatcacga ttgagcagga gcctctagga
      301 cccaaagaag gcacagagga agagagcgaa gatgaacgtc agaaagggtt cttggaaagg
      361 aagtatgata cggtttgtga gttttgtaga aagcacagag tcattctcca gcacaccatc
      421 tgggcagttt tactgacagg tttcctggcc ctggtgattg cagcctgtgc actaaacttc
      481 caccgagccc ttcccctttt tgtgatcacc ttggtgacca tcttcttcgt cgtctgggat
      541 cgcttgatgg ccaaatacga acagcgaatc gatgatgtcc tgtctcccgg caaaaggctg
      601 cttgagaggc attggttctg gctgaagtgg gtggtctggt gctcactgat cttggcggtc
      661 attctctggc tggctctgga cacggccagg ctgggccaac agcagctgat atcctttggt
      721 gggctcgtca tgtatattgt tctgctattc ctgttttcca agcatccgac cagagtttac
      781 tggaggcctg tcttttgggg aattggactg cagtttcttc ttgggctctt aattctaagg
      841 actaggcctg gatttgttgc ttttgattgg atggggaaac aagttcagac ttttctgggg
      901 tacactgacg ctggagccca gtttgtcttt ggagaaaagt atacagacca cttctttgca
      961 tttaagatcc ttcccattgt ggttttcttc agcaccgtga tgtctatgct ctattatctg
     1021 ggactgatgc agtggattat cagaaaggtt gggtggctaa tgcttgtcac tatggggtca
     1081 tctcccattg agtccgtagt tgctgctggc aacatatttg ttgggcaaac agagtctcca
     1141 ctactggttc aaccatatct accacacgtc accaagtcag aactgcacac catcatgaca
     1201 gctggttttg ccacgattgc tgggagcgtg ttgggcgcgt acatctcttt tggggtgtca
     1261 tctacacact tgctcaccgc ttctgtcatg tcggcgcctg cagccctggc tgtggccaaa
     1321 ctcttttggc ctgaaacaga gaaacccaaa ataaccctca agaatgccat gaaaatggaa
     1381 aatggtgatt cccggaatct cctggaggcg gccacgcagg gtgcatcttc gtccatcccc
     1441 ctggtggcaa acatcgctgc aaatctgatc gccttcctgg ccttgctttc ctttgtgaac
     1501 tccgctctgt cttggtttgg aagcatgttc gactacccac agctgagttt cgagctcatt
     1561 tgttcttaca tcttcatgcc tttctccttc atgatgggag tcgactggca agacagcttt
     1621 atggtcgcca aactcatagg ctacaagacg ttcttcaatg aatttgtggc ttatgaacac
     1681 ctctcaaaat tcatcaattt gaggaaagcg gctggaccca aatttgtgaa tggtgtgcag
     1741 caatatatgt caattcgctc ggagaccatc gcaacttacg ccctctgtgg ttttgccaat
     1801 ttcggttccc taggaatagt gatcggtgga cttacgtcca tagctccgtc cagaaagcga
     1861 gacattgcct cgggagccat gagagccctg attgctggga ccattgcctg cttcatgaca
     1921 gcctgcatcg ctggcatgct ctctgacacc ccggtggcta tcaactgcca ccacgttcta
     1981 gagagcagca aagtactcag caacacaact gaagtggcgt cttgctgtca agacctgttc
     2041 aacagcactg ttgccagggg accaaatgac gtcctcccag gaggaaactt cagcctctac
     2101 actttgaaga gctgctgcaa cctgctgaaa ccaccaacgc tgaactgtgg ttggatccct
     2161 aacataccgt gatctc
//
