LOCUS       NM_001100706            3067 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus solute carrier family 27 member 4 (Slc27a4),
            mRNA.
ACCESSION   NM_001100706 XM_001079409 XM_231115
VERSION     NM_001100706.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3067)
  AUTHORS   Kolieb,E., Maher,S.A., Shalaby,M.N., Alsuhaibani,A.M., Alharthi,A.,
            Hassan,W.A. and El-Sayed,K.
  TITLE     Vitamin D and Swimming Exercise Prevent Obesity in Rats under a
            High-Fat Diet via Targeting FATP4 and TLR4 in the Liver and Adipose
            Tissue
  JOURNAL   Int J Environ Res Public Health 19 (21), 13740 (2022)
   PUBMED   36360622
  REMARK    GeneRIF: Vitamin D and Swimming Exercise Prevent Obesity in Rats
            under a High-Fat Diet via Targeting FATP4 and TLR4 in the Liver and
            Adipose Tissue.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3067)
  AUTHORS   Li,S., Lee,J., Zhou,Y., Gordon,W.C., Hill,J.M., Bazan,N.G.,
            Miner,J.H. and Jin,M.
  TITLE     Fatty acid transport protein 4 (FATP4) prevents light-induced
            degeneration of cone and rod photoreceptors by inhibiting RPE65
            isomerase
  JOURNAL   J Neurosci 33 (7), 3178-3189 (2013)
   PUBMED   23407971
REFERENCE   3  (bases 1 to 3067)
  AUTHORS   Mitchell,R.W., On,N.H., Del Bigio,M.R., Miller,D.W. and Hatch,G.M.
  TITLE     Fatty acid transport protein expression in human brain and
            potential role in fatty acid transport across human brain
            microvessel endothelial cells
  JOURNAL   J Neurochem 117 (4), 735-746 (2011)
   PUBMED   21395585
REFERENCE   4  (bases 1 to 3067)
  AUTHORS   Krammer,J., Digel,M., Ehehalt,F., Stremmel,W., Fullekrug,J. and
            Ehehalt,R.
  TITLE     Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and
            ACSL1 increases fatty acid uptake in human hepatoma cells
  JOURNAL   Int J Med Sci 8 (7), 599-614 (2011)
   PUBMED   22022213
REFERENCE   5  (bases 1 to 3067)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 3067)
  AUTHORS   Gertow,K., Pietilainen,K.H., Yki-Jarvinen,H., Kaprio,J.,
            Rissanen,A., Eriksson,P., Hamsten,A. and Fisher,R.M.
  TITLE     Expression of fatty-acid-handling proteins in human adipose tissue
            in relation to obesity and insulin resistance
  JOURNAL   Diabetologia 47 (6), 1118-1125 (2004)
   PUBMED   15168018
REFERENCE   7  (bases 1 to 3067)
  AUTHORS   Gimeno,R.E., Hirsch,D.J., Punreddy,S., Sun,Y., Ortegon,A.M., Wu,H.,
            Daniels,T., Stricker-Krongrad,A., Lodish,H.F. and Stahl,A.
  TITLE     Targeted deletion of fatty acid transport protein-4 results in
            early embryonic lethality
  JOURNAL   J Biol Chem 278 (49), 49512-49516 (2003)
   PUBMED   14512415
REFERENCE   8  (bases 1 to 3067)
  AUTHORS   Herrmann,T., van der Hoeven,F., Grone,H.J., Stewart,A.F.,
            Langbein,L., Kaiser,I., Liebisch,G., Gosch,I., Buchkremer,F.,
            Drobnik,W., Schmitz,G. and Stremmel,W.
  TITLE     Mice with targeted disruption of the fatty acid transport protein 4
            (Fatp 4, Slc27a4) gene show features of lethal restrictive
            dermopathy
  JOURNAL   J Cell Biol 161 (6), 1105-1115 (2003)
   PUBMED   12821645
REFERENCE   9  (bases 1 to 3067)
  AUTHORS   Herrmann,T., Buchkremer,F., Gosch,I., Hall,A.M., Bernlohr,D.A. and
            Stremmel,W.
  TITLE     Mouse fatty acid transport protein 4 (FATP4): characterization of
            the gene and functional assessment as a very long chain acyl-CoA
            synthetase
  JOURNAL   Gene 270 (1-2), 31-40 (2001)
   PUBMED   11404000
REFERENCE   10 (bases 1 to 3067)
  AUTHORS   Stahl,A., Hirsch,D.J., Gimeno,R.E., Punreddy,S., Ge,P., Watson,N.,
            Patel,S., Kotler,M., Raimondi,A., Tartaglia,L.A. and Lodish,H.F.
  TITLE     Identification of the major intestinal fatty acid transport protein
  JOURNAL   Mol Cell 4 (3), 299-308 (1999)
   PUBMED   10518211
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On or before May 13, 2010 this sequence version replaced
            XM_001079409.2, XM_231115.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.13118.1,
                                           SRR26643293.15791.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-326               JAXUCZ010000003.1  33472903-33473228
            327-493             JAXUCZ010000003.1  33474438-33474604
            494-888             JAXUCZ010000003.1  33475896-33476290
            889-1047            JAXUCZ010000003.1  33477664-33477822
            1048-1117           JAXUCZ010000003.1  33479358-33479427
            1118-1209           JAXUCZ010000003.1  33479531-33479622
            1210-1319           JAXUCZ010000003.1  33480480-33480589
            1320-1529           JAXUCZ010000003.1  33480790-33480999
            1530-1656           JAXUCZ010000003.1  33481141-33481267
            1657-1794           JAXUCZ010000003.1  33481821-33481958
            1795-1959           JAXUCZ010000003.1  33482138-33482302
            1960-2106           JAXUCZ010000003.1  33482378-33482524
            2107-3067           JAXUCZ010000003.1  33484864-33485824
FEATURES             Location/Qualifiers
     source          1..3067
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..3067
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /note="solute carrier family 27 member 4"
                     /db_xref="GeneID:311839"
                     /db_xref="RGD:1307383"
     exon            1..326
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            327..493
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     CDS             333..2264
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /EC_number="6.2.1.-"
                     /note="fatty acid transport protein 4; solute carrier
                     family 27 (fatty acid transporter), member 4"
                     /codon_start=1
                     /product="long-chain fatty acid transport protein 4"
                     /protein_id="NP_001094176.1"
                     /db_xref="GeneID:311839"
                     /db_xref="RGD:1307383"
                     /translation="MLLGASLVGALLFSKLVLKLPWTQVGFSLLLLYLGSGGWRFIRV
                     FIKTVRRDVFGGMVLLKVKTKVRRYLQERKTVPLLFASVVRRHPDKTALIFEGTNTHW
                     TFRQLDDYSSSVANFLQARGLVSGNVVALFMENRNEFVGLWLGMAKLGVEAALINTNL
                     RRDALRHCLDTSKARALIFGSEMASAVYEIQAILDPTLTLFCSGSWEPSTVPANTEHL
                     DPLLEDAPKHLPSIPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRM
                     RPDDIVYDCLPLYHSAGNIVGIGQCVLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYI
                     GELCRYLLNQPPREAESRHKVRMALGNGLRQSIWTDFSSRFHIPQVAEFYGATECNCS
                     LGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGQPGQLVGR
                     IIQQDPLRRFDGYLNQGANNKKIASDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDT
                     FRWKGENVSTTEVEGTLSRLLQMADVAVYGVEVPGAEGRAGMAAVASPTSNCDLESFA
                     QTLKKELPLYARPIFLRFLPELHKTGTFKFQKTELRKEGFDPSVVKDPLFYLDARTGC
                     YVALDQEAYTRIQAGEEKL"
     exon            494..888
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            889..1047
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1117
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1209
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1319
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1529
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1656
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1794
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1959
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2106
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
     exon            2107..3067
                     /gene="Slc27a4"
                     /gene_synonym="Fatp4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtggcgcgc gcagggctga aggggctggg cggtgtcggg cgcgctgagg ctgggttgcg
       61 ctgtggaaca cgggctcaga agctcgccct ctgcggggac ggcagggaag gcggtgctgc
      121 cggccggcac agccggtgcg ggtgcgggag gcgggtgggg gtggagcgcg acagaggtac
      181 agaccctaca agggcgagga gtgggccaga cgcgccgaac tcggctgtgt gcgccccggg
      241 gcggccgatg cccccagcgc atcgcactcc gctgccgcaa ccgggccgca tcctgacggg
      301 gctccgcgcc gcgcagccgc agccaggcca caatgctgct tggagcatct ctggtggggg
      361 cgctgctgtt ctccaagctg gtgctgaagc taccctggac ccaggtggga ttctccttgt
      421 tgctcctgta cttggggtct ggtggctggc gtttcatccg ggtcttcatc aagacggtca
      481 ggagagatgt cttcggcggc atggtgctcc tgaaggtgaa gaccaaggtc cgacggtacc
      541 ttcaggagcg gaagacagtg cccttgctgt ttgcctcagt ggttcggcgc caccccgaca
      601 agacagccct gattttcgag ggcacgaata ctcactggac cttccgccag ctggatgact
      661 actccagcag tgtggccaac ttcctgcagg cccggggcct ggtctcaggc aatgtagttg
      721 ctctctttat ggaaaaccgt aacgagtttg tgggtctgtg gctaggcatg gccaagctgg
      781 gcgtggaggc ggcactcatc aacaccaacc ttaggcggga tgccctgcgc cactgccttg
      841 acacctcaaa ggcacgagcc ctcatctttg gcagcgagat ggcctcagct gtctatgaga
      901 tccaggctat cctggacccc acactcaccc tcttctgctc tggttcctgg gagcccagca
      961 ccgtgcctgc caacacagag catctggacc ctctgctgga agatgccccg aagcacctgc
     1021 ccagcatccc agacaagggt tttacagata agctcttcta tatctacacg tcgggcacca
     1081 cggggctacc caaagctgcc attgtggtgc acagcaggta ttaccgaatg gctgccctgg
     1141 tgtactatgg attccgcatg cggcctgatg acattgtcta tgactgcctc cccctctacc
     1201 actcagcagg aaacattgtg gggattggcc agtgcgtact ccacggcatg actgtggtga
     1261 tccggaagaa gttttcagcc tcccggttct gggatgactg tatcaagtac aactgcacaa
     1321 ttgtacagta cattggtgag ctttgccgct acctcctgaa ccagccaccc cgtgaggctg
     1381 agtctcggca caaggtgcgc atggcactgg gcaacggtct ccggcagtcc atctggaccg
     1441 acttctccag ccgtttccac attccccaag tggccgagtt ctacggggcc accgagtgca
     1501 actgtagctt gggcaacttt gacagccagg tgggggcctg tggcttcaat agccgcatcc
     1561 tgtcctttgt gtaccccatc cgcttggtac gagtcaatga ggataccatg gaactgatcc
     1621 ggggacccga tggcgtctgc attccctgtc aaccaggcca gccaggccag ctggtgggtc
     1681 gcatcatcca gcaggacccc ctacgccgtt ttgatggcta cctcaaccag ggtgccaaca
     1741 acaagaagat tgctagtgat gtcttcaaga aaggggacca agcctacctc actggtgacg
     1801 tgctggtgat ggatgagctg ggctacctgt acttccgaga ccgcacaggg gacacgttcc
     1861 gctggaaagg ggagaatgtg tctaccactg aagtggaggg cacactcagc cgcctgcttc
     1921 agatggcaga tgtggctgtt tatggtgttg aggtgccagg agctgagggc cgagcaggaa
     1981 tggctgctgt ggcaagcccc actagcaact gtgacctgga gagctttgca cagaccttga
     2041 aaaaggagct gcccctgtac gcccgcccca tcttcctccg cttcttgcct gagctgcaca
     2101 aaacaggaac cttcaagttc cagaagacag agttgcggaa ggagggcttt gacccgtctg
     2161 ttgtgaaaga cccactcttc tatttggatg cccggacagg ctgctatgtt gcactggacc
     2221 aagaggccta tacccgcatc caggcaggcg aggagaagct gtgatttccc ccacatccct
     2281 ctgagggcca gaggatgctg gattcagagc cccagcttcc accccagagg ggtcctgggc
     2341 aaggccagac caaagctagc agggcccgca cctccacccc taggtgctga tccccctctc
     2401 ccaaactgcc aagtgactga ctcactgccg cttcccccac cctccagagg ctttctgtga
     2461 aagtctcatc caagctgtgt cttctggtcc aggcgtggcc cctggctcca ggcttactga
     2521 caggcacctt taggatgatg tcttgggtcc agcgggccag gatgtgggag aggagtcact
     2581 gagatccctc caaaaagaag ggagcttaca aatgaaccaa gacaaaagcc tctcgactca
     2641 ggaagctaag tggccagaga ctgaagtggc cagccatccc gtgtccacag aggatcttgg
     2701 tccaaagctg ccaaagtgtc acctagccct gtctgcacct ctggggaaag gaggacagca
     2761 tgtggccaaa gtgtcactta gccctgtctg cacctctggg gaaaggagga cagcatgtgg
     2821 ccactgggcc cctgtctcaa gaagtcggga tcgcacacac acacacactc cttgtttctc
     2881 cagattccct tgtccttgtc ttagggaggg aggggggtgt cctgtctgtc tctcagatgc
     2941 aggcttcctg cctgtctgtg agtctgtccc tgtgtgttgc cttctccatc tgtcctagcc
     3001 tgactgtggg tggagagggc atgaggggag gctcaggggc taataaactc tgccttgact
     3061 cctctta
//
