LOCUS       NM_001106638            2285 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus solute carrier family 26 member 7 (Slc26a7),
            mRNA.
ACCESSION   NM_001106638 XM_001055767 XM_232793
VERSION     NM_001106638.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2285)
  AUTHORS   Kiriya,M., Kawashima,A., Fujiwara,Y., Tanimura,Y., Yoshihara,A.,
            Nakamura,Y., Tanigawa,K., Kondo,T. and Suzuki,K.
  TITLE     Thyroglobulin regulates the expression and localization of the
            novel iodide transporter solute carrier family 26 member 7
            (SLC26A7) in thyrocytes
  JOURNAL   Endocr J 69 (10), 1217-1225 (2022)
   PUBMED   35644541
  REMARK    GeneRIF: Thyroglobulin regulates the expression and localization of
            the novel iodide transporter solute carrier family 26 member 7
            (SLC26A7) in thyrocytes.
REFERENCE   2  (bases 1 to 2285)
  AUTHORS   Yin,K., Lei,Y., Wen,X., Lacruz,R.S., Soleimani,M., Kurtz,I.,
            Snead,M.L., White,S.N. and Paine,M.L.
  TITLE     SLC26A Gene Family Participate in pH Regulation during Enamel
            Maturation
  JOURNAL   PLoS One 10 (12), e0144703 (2015)
   PUBMED   26671068
  REMARK    GeneRIF: Slc26a1, Slc26a6 and Slc26a7 are novel participants in the
            extracellular transport of bicarbonate during enamel maturation.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2285)
  AUTHORS   Sun,X. and Petrovic,S.
  TITLE     Increased acid load and deletion of AE1 increase Slc26a7 expression
  JOURNAL   Nephron Physiol 109 (3), p29-p35 (2008)
   PUBMED   18663336
  REMARK    GeneRIF: Suggest that the increase in Slc26a7 expression caused by
            acid challenge represents an adaptive response, indicating that
            Slc26a7 contributes to the regulation of acid-base balance by the
            kidney.
REFERENCE   4  (bases 1 to 2285)
  AUTHORS   Barone,S., Amlal,H., Kujala,M., Xu,J., Karet,F., Blanchard,A.,
            Kere,J. and Soleimani,M.
  TITLE     Regulation of the basolateral chloride/base exchangers AE1 and
            SLC26A7 in the kidney collecting duct in potassium depletion
  JOURNAL   Nephrol Dial Transplant 22 (12), 3462-3470 (2007)
   PUBMED   17804457
REFERENCE   5  (bases 1 to 2285)
  AUTHORS   Kosiek,O., Busque,S.M., Foller,M., Shcheynikov,N., Kirchhoff,P.,
            Bleich,M., Muallem,S. and Geibel,J.P.
  TITLE     SLC26A7 can function as a chloride-loading mechanism in parietal
            cells
  JOURNAL   Pflugers Arch 454 (6), 989-998 (2007)
   PUBMED   17404755
  REMARK    GeneRIF: SLC26A7 is a Cl(-) uptake system under histamine
            stimulation
REFERENCE   6  (bases 1 to 2285)
  AUTHORS   Petrovic,S., Amlal,H., Sun,X., Karet,F., Barone,S. and Soleimani,M.
  TITLE     Vasopressin induces expression of the Cl-/HCO3- exchanger SLC26A7
            in kidney medullary collecting ducts of Brattleboro rats
  JOURNAL   Am J Physiol Renal Physiol 290 (5), F1194-F1201 (2006)
   PUBMED   16352747
  REMARK    GeneRIF: vasopressin increases the expression of SLC26A7 protein
            through posttranscriptional mechanisms in the outer medullary
            collecting duct
REFERENCE   7  (bases 1 to 2285)
  AUTHORS   Kim,K.H., Shcheynikov,N., Wang,Y. and Muallem,S.
  TITLE     SLC26A7 is a Cl- channel regulated by intracellular pH
  JOURNAL   J Biol Chem 280 (8), 6463-6470 (2005)
   PUBMED   15591059
REFERENCE   8  (bases 1 to 2285)
  AUTHORS   Petrovic,S., Ju,X., Barone,S., Seidler,U., Alper,S.L., Lohi,H.,
            Kere,J. and Soleimani,M.
  TITLE     Identification of a basolateral Cl-/HCO3- exchanger specific to
            gastric parietal cells
  JOURNAL   Am J Physiol Gastrointest Liver Physiol 284 (6), G1093-G1103 (2003)
   PUBMED   12736153
REFERENCE   9  (bases 1 to 2285)
  AUTHORS   Lohi,H., Kujala,M., Makela,S., Lehtonen,E., Kestila,M.,
            Saarialho-Kere,U., Markovich,D. and Kere,J.
  TITLE     Functional characterization of three novel tissue-specific anion
            exchangers SLC26A7, -A8, and -A9
  JOURNAL   J Biol Chem 277 (16), 14246-14254 (2002)
   PUBMED   11834742
REFERENCE   10 (bases 1 to 2285)
  AUTHORS   Mocellin,R. and Buhlmeyer,K.
  TITLE     Late banding operation in children with ventricular septal defect
            and pulmonary arterial hypertension
  JOURNAL   Eur J Cardiol 3 (3), 205-211 (1975)
   PUBMED   1183472
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473962.1.
            
            [WARNING] On Mar 18, 2025 this sequence was replaced by
            NM_001106638.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_232793.4, XM_001055767.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760384
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2285
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q13"
     gene            1..2285
                     /gene="Slc26a7"
                     /note="solute carrier family 26 member 7"
                     /db_xref="GeneID:297910"
                     /db_xref="RGD:1310846"
     exon            1..70
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            71..291
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1904
                     /gene="Slc26a7"
                     /note="solute carrier family 26 (anion exchanger), member
                     7"
                     /codon_start=1
                     /product="anion exchange transporter"
                     /protein_id="NP_001100108.1"
                     /db_xref="GeneID:297910"
                     /db_xref="RGD:1310846"
                     /translation="MTGAKRKKRSVLWGKMHTPHREDIKQWCKRRLPILEWAPQYNLK
                     ENLLPDTVSGVLLAVQQVTQGLSFAILSSVHPVFGLYGSLFPAIIYAIFGMGRHVATG
                     TFALTSLISANAVERLVPQSNRNLTTQSNSSVLGLSEFELQRIGVAAAVSFLGGVIQI
                     YAYVFENIKSVQLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLIIAASFAC
                     YCTNMENTYGLEVVGRIPKGIPPPRAPPMNILSAVLTEAFGVALVGYVASLALAQGSA
                     KKFKYSVDDNQEFLAHGLSNVIPSFLFCIPSAAAMGRTAGLYSTGAKTQVACLISCIF
                     VLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWISTYIF
                     TICFAANVGLLFGVVCTIAIVLGRFPRAKTLSITDMKEMELKVKTETYDENSQQIKII
                     SINNPLVFLNAKKFSADLMKIILKETDGSQALDDVSKCEQNTLLSPLPNGSCTEEASQ
                     PCPSEKYSLVLNCSGLTFFDYTGVSTLVELYLDCKSRSVDVFLANCTASLIKAMTYYG
                     DLDTEKPIFFDSVATAISVIQSNKNLSKDTDHSEV"
     exon            292..402
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            403..575
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            576..728
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            729..811
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            812..959
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1073
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1151
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1247
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1354
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1421
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1559
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1560..1608
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1609..1709
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1710..1764
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1868
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1869..2285
                     /gene="Slc26a7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attccttttc caagatcaga aaagtagtac atgaacaggg acccatttct tattgagata
       61 agaactcaag ttgactacta caggagggaa tctgagaaat gacgggggca aagaggaaaa
      121 agagaagcgt gctgtggggc aagatgcaca ccccccaccg agaagacatt aaacagtggt
      181 gtaagaggcg cctacctatc ttggaatggg caccgcagta caatctgaag gaaaacctgc
      241 ttccagacac cgtgtctggc gtactgttgg cagttcaaca ggtgacacaa gggctgtcct
      301 tcgctattct ttcatctgta cacccagttt ttggtttata cggatctctg tttcctgcca
      361 tcatttatgc gatatttgga atgggacgcc atgttgccac aggcaccttt gccttgacgt
      421 ccttgatatc agccaatgct gtggaacggc tggtccctca gagcaataga aacctcacca
      481 cacagagcaa ctcaagcgtg ctgggcttat cggagtttga gctgcagaga atcggggttg
      541 cagcagccgt ttcattcttg ggcggagtga ttcagatcta tgcgtatgtt tttgagaaca
      601 tcaagtctgt ccagctggaa gcactgctct tgtccttgct gagcattgtt gtccttgtcc
      661 tcgttaaaga gctgaacgag cagtttaaga gaaagattaa agttgttctt cctgtcgact
      721 tagttttgat cattgctgcc tcatttgctt gctattgtac caacatggaa aacacatacg
      781 gattagaagt agttgggcgc attccaaaag ggatccctcc gccccgtgct cccccaatga
      841 acatcctctc cgcagtgctc acggaagctt tcggagttgc acttgtaggc tacgtggcct
      901 cgctggctct cgcacaagga tctgccaaga agttcaaata ttcagttgat gacaaccagg
      961 aatttttggc ccatggcctc agcaacgtga ttccttcatt tctcttctgc atcccaagcg
     1021 ccgccgccat gggaaggaca gctggtctgt acagcacggg ggcaaagaca caggtggctt
     1081 gtctaatatc ttgcattttc gtccttatag tcatctatgc aataggaccc ttgctgtact
     1141 ggctgcccat gtgcgttctt gcaagtatta ttgttgtggg actgaaagga atgttaatac
     1201 agttccggga tttaaaaaaa tactggaatg tggataaaat cgattggggc atatggatca
     1261 gcacttacat ttttacaata tgcttcgctg ccaacgtggg actgctcttt ggtgttgtct
     1321 gcaccatagc tatcgtgtta gggcgtttcc caagggcaaa gactttaagc ataacagaca
     1381 tgaaagaaat ggaattgaag gtgaagacag aaacgtatga tgaaaactcg caacagataa
     1441 aaatcatctc aataaacaac ccacttgttt tcctgaatgc aaagaaattt agtgctgatc
     1501 ttatgaaaat aatcctaaag gaaactgacg gcagccaagc acttgatgat gtcagcaagt
     1561 gtgaacagaa caccttgctc agtcccctgc ccaacgggag ctgcactgaa gaagcctccc
     1621 agccctgccc cagtgagaag tattctttgg tcctgaattg cagtggcttg acctttttcg
     1681 actacacagg agtctccaca cttgttgagc tctaccttga ttgcaagagc aggagtgtgg
     1741 atgtgttctt agccaactgt acagcatcct tgataaaagc gatgacatac tatggagacc
     1801 tagacactga aaaaccaatt ttttttgact cggtagccac tgcaataagt gtcatccaat
     1861 caaataagaa tttgagcaag gacactgacc acagtgaagt ctgaggtcca cgcattgaaa
     1921 tgcacatctc atctttagca cctgccccaa agaggccaga tactggcatt ttgcactcat
     1981 tttggtgtat atactgtata tctcttaatt agaatgatgt gagttggcaa ctggatagcc
     2041 actggccaag acttgctgac atcctatttt ttctaatttt tcttaataaa cagattcatt
     2101 agttatttca tataggcatc aatatgcatg tagctttagt ttaatgaaca gtaaacatgc
     2161 ttttatttcc agttataaga gtattttgta tggtttcatt tttgttgtaa gctaacaaat
     2221 ggagaaatat ttttatcaga aatggtttgg attatttata aaccattcat aaaaaaatta
     2281 agatc
//
