LOCUS       NM_001398807            2435 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus solute carrier family 26 member 11 (Slc26a11),
            mRNA.
ACCESSION   NM_001398807 XM_039087530
VERSION     NM_001398807.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2435)
  AUTHORS   Wei,S., Chen,B., Low,S.W., Poore,C.P., Gao,Y., Nilius,B. and
            Liao,P.
  TITLE     SLC26A11 Inhibition Reduces Oncotic Neuronal Death and Attenuates
            Stroke Reperfusion Injury
  JOURNAL   Mol Neurobiol 60 (10), 5931-5943 (2023)
   PUBMED   37380823
  REMARK    GeneRIF: SLC26A11 Inhibition Reduces Oncotic Neuronal Death and
            Attenuates Stroke Reperfusion Injury.
REFERENCE   2  (bases 1 to 2435)
  AUTHORS   Rungta,R.L., Choi,H.B., Tyson,J.R., Malik,A., Dissing-Olesen,L.,
            Lin,P.J.C., Cain,S.M., Cullis,P.R., Snutch,T.P. and MacVicar,B.A.
  TITLE     The cellular mechanisms of neuronal swelling underlying cytotoxic
            edema
  JOURNAL   Cell 161 (3), 610-621 (2015)
   PUBMED   25910210
  REMARK    GeneRIF: Results demonstrate that prolonged Na+ entry via either of
            two independent pathways (either VGSCs or NMDARs) converge to
            activate a Cl- influx pathway via SLC26A11 that is ultimately
            required for neuronal swelling and subsequent cell death.
REFERENCE   3  (bases 1 to 2435)
  AUTHORS   Schroder,B.A., Wrocklage,C., Hasilik,A. and Saftig,P.
  TITLE     The proteome of lysosomes
  JOURNAL   Proteomics 10 (22), 4053-4076 (2010)
   PUBMED   20957757
  REMARK    Review article
REFERENCE   4  (bases 1 to 2435)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 2435)
  AUTHORS   Vincourt,J.B., Jullien,D., Amalric,F. and Girard,J.P.
  TITLE     Molecular and functional characterization of SLC26A11, a
            sodium-independent sulfate transporter from high endothelial
            venules
  JOURNAL   FASEB J 17 (8), 890-892 (2003)
   PUBMED   12626430
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Dec 23, 2021 this sequence version replaced XM_039087530.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.42003.1,
                                           SRR26643299.46879.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-127               JAXUCZ010000010.1  105112020-105112146
            128-354             JAXUCZ010000010.1  105113217-105113443
            355-547             JAXUCZ010000010.1  105114414-105114606
            548-633             JAXUCZ010000010.1  105115472-105115557
            634-713             JAXUCZ010000010.1  105117732-105117811
            714-856             JAXUCZ010000010.1  105118999-105119141
            857-1032            JAXUCZ010000010.1  105123111-105123286
            1033-1105           JAXUCZ010000010.1  105123722-105123794
            1106-1156           JAXUCZ010000010.1  105125762-105125812
            1157-1217           JAXUCZ010000010.1  105127625-105127685
            1218-1273           JAXUCZ010000010.1  105128883-105128938
            1274-1414           JAXUCZ010000010.1  105129116-105129256
            1415-1542           JAXUCZ010000010.1  105130545-105130672
            1543-1642           JAXUCZ010000010.1  105130934-105131033
            1643-1776           JAXUCZ010000010.1  105131444-105131577
            1777-1849           JAXUCZ010000010.1  105133527-105133599
            1850-2435           JAXUCZ010000010.1  105133808-105134393
FEATURES             Location/Qualifiers
     source          1..2435
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.3"
     gene            1..2435
                     /gene="Slc26a11"
                     /note="solute carrier family 26 member 11"
                     /db_xref="GeneID:360670"
                     /db_xref="RGD:1306178"
     exon            1..127
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            128..354
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..1953
                     /gene="Slc26a11"
                     /note="solute carrier family 26 (anion exchanger), member
                     11"
                     /codon_start=1
                     /product="sodium-independent sulfate anion transporter"
                     /protein_id="NP_001385736.1"
                     /db_xref="GeneID:360670"
                     /db_xref="RGD:1306178"
                     /translation="MAPDTHCCSRADLRRRLPVLAWLPNYSLRWLRMDVIAGLSVGLT
                     VIPQALAYAEVAGLPPQYGLYSAFMGCFVYFVLGTSRDVTLGPTAIMSLLVSYYTFRE
                     PAYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQVKNLLGLQ
                     NIPRQFFLQVYHTFLHIGETRVGDAILGLVCMVLLLVLKLMREHIPPPHPEMPLGVKF
                     SRGLVWTVTTARNALVVSFAALIAYAFEVTGSHPFILTGKIAQGLPPVRMPPFSVTTD
                     NKTISFSEMVQDMGVGLAVVPLMGLLETIAVAKSFASQNNYRIDANQELLAIGLTNVL
                     GSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGVLVLLSLDYLTLLFYYIPKSALAA
                     VIIMAVAPLFDVKIFRRLWLVQRLDLLPLCVTFLLSFWEIQYGILAGTLVSLLILLHS
                     VARPKTQVSEGQILVLQPASGLHFPAVDALREAMTKRALEASPPRSAVLECTHVSNID
                     YTVILGLGELLEDFQKKGVTLAFVGLQVPVLRTLLAADLKGFQYFTTLEEAEKSLQQE
                     PGTQPYSIREDTAPEHRSSLLKSPSGP"
     exon            355..547
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            548..633
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            634..713
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            714..856
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            857..1032
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1105
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1156
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1217
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1273
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1414
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1542
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1642
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1776
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1849
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1850..2435
                     /gene="Slc26a11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctcggccc ctccacaggg tcacgtgcac ggcaggctcc gcccatgtac tgcccactct
       61 gttcctgaga ttcctgagga ctcagctacg gccacttcgg aggaccccga gcctcggcgt
      121 tcggtggctt tgtaaaaggt ctgggtcagg ccagatcccc ccagcctgat catggcacca
      181 gacacacact gctgctccag ggcagacctg aggaggaggc tacccgtcct ggcctggctg
      241 cccaactact ctctgcggtg gctgagaatg gacgtcatcg ctggactctc cgtgggtctc
      301 accgtcatcc cccaggccct ggcctatgca gaagtggctg gactcccgcc ccagtacggt
      361 ctctactctg ccttcatggg gtgcttcgtg tacttcgtcc tgggcacctc ccgggatgtg
      421 actctgggcc ccacggctat catgtctctc ctggtatcct actacacctt ccgtgagcct
      481 gcctatgccg tgctgcttgc cttcctgtct gggtgtatcc agttggccat ggggctcctg
      541 catttggggt tcctgctgga cttcatctcc tgccctgtca ttaaaggctt cacatccgct
      601 gccagcatca caattggctt tggacaggtc aagaacctgc tgggattaca gaacatcccc
      661 cggcagttct tcctccaggt gtaccacacc ttcctccaca tcggagagac cagggtgggc
      721 gatgccatcc tgggactggt ctgcatggtg ctgctgcttg tgctgaagct tatgcgtgaa
      781 cacattcctc ctccccatcc tgagatgccc cttggcgtga agttcagccg tgggctagtg
      841 tggaccgtca caacagctcg caacgccttg gtggtctcct tcgcggccct gattgcttac
      901 gccttcgagg tgacaggatc ccatccgttc attctgactg gaaagatcgc ccaggggctc
      961 cctcctgtga ggatgccgcc cttctcagtg accacagaca ataagaccat ctctttctct
     1021 gagatggtgc aggacatggg ggtcggactg gctgtggtgc ctctgatggg cctcctggag
     1081 accattgctg tggccaaatc cttcgcctcc cagaataatt accgcattga tgccaaccag
     1141 gagctgctgg ccatcggcct caccaatgtg ctgggctccc tagtctcgtc ttacccggtc
     1201 actggcagct ttgggcggac agcagtgaat gcccagacgg gggtgtgtac cccggcagga
     1261 ggcctggtga ctggtgtcct ggtgctgctg tctctggact acctgacctt actgttctac
     1321 tatatcccca agtctgcact ggctgccgtc atcatcatgg ctgtggcccc gctctttgac
     1381 gtcaagatct tcaggaggct ctggcttgtt cagaggctgg acctgttacc actctgcgtg
     1441 acattcctgc tgtccttctg ggagatccaa tacggcatcc tggcagggac cctggtgtct
     1501 ttgctcattc tcctgcactc tgtagctaga cccaagaccc aggtgtcaga gggacagatt
     1561 cttgttctcc agccggccag cggcctgcac ttccctgcag ttgatgccct ccgagaggca
     1621 atgacgaaga gggccctgga agcatcccca ccacgttctg cggttctgga gtgcacgcat
     1681 gtcagcaata tagactacac cgtgattttg ggactcggtg agctcctgga ggacttccag
     1741 aagaaaggtg tcaccctggc ctttgttggc ctacaggtgc ccgtgctccg cacactcttg
     1801 gctgctgacc tcaagggttt ccagtacttt accactctgg aggaggcaga gaaatccctg
     1861 cagcaggaac cagggactca gccttacagc atccgtgaag acactgcccc agagcacagg
     1921 agctccctac tgaagtctcc ctcgggcccc tgaacggcag ctggtatagg aagggtctct
     1981 ggaaggttct gtcgctgtga cttggtgtca cctgatagac tcaccaacct ggcgggactg
     2041 aaatggctct agggaagagc agggagccat gtgtgattcc ggggtgtccc ctaggtgtga
     2101 gtatttgagg ggtggggtgg ctagacagtc ttccagagag agagagagag agaccaagaa
     2161 aggtggggaa tcatgtcttt tggcctgggc tggcagggta agctggcatt ttccagatct
     2221 caagtccttc tttggaatca gaccctacca gagaagagtc agagagaccg ggcatctcag
     2281 agatgtgtct gaccatggcg tgaagacgaa cctgagctga agaggcgacc acagtgtgcc
     2341 acacaaggtc aattctgttt aaaatcacgt gttttgaagt ggaagtcact ctggtgtttt
     2401 tgtaaagcaa tacgaacact aatccttggc ttttt
//
