LOCUS       NM_001001509            1550 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus solute carrier family 25, member 47 (Slc25a47),
            mRNA.
ACCESSION   NM_001001509 XM_234551
VERSION     NM_001001509.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1550)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1550)
  AUTHORS   Jin,X., Yang,Y.D., Chen,K., Lv,Z.Y., Zheng,L., Liu,Y.P., Chen,S.H.,
            Yu,C.H., Jiang,X.Y., Zhang,C.Y. and Li,Y.M.
  TITLE     HDMCP uncouples yeast mitochondrial respiration and alleviates
            steatosis in L02 and hepG2 cells by decreasing ATP and H2O2 levels:
            a novel mechanism for NAFLD
  JOURNAL   J Hepatol 50 (5), 1019-1028 (2009)
   PUBMED   19303656
  REMARK    GeneRIF: HDMCP might function through promoting ATP depletion and
            decreasing H(2)O(2) production.
REFERENCE   3  (bases 1 to 1550)
  AUTHORS   Tan,M.G., Ooi,L.L., Aw,S.E. and Hui,K.M.
  TITLE     Cloning and identification of hepatocellular carcinoma
            down-regulated mitochondrial carrier protein, a novel
            liver-specific uncoupling protein
  JOURNAL   J Biol Chem 279 (43), 45235-45244 (2004)
   PUBMED   15322095
  REMARK    GeneRIF: hepatocellular carcinoma down-regulated mitochondrial
            carrier protein is a novel liver-specific uncoupling protein
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY603424.1.
            
            On Aug 30, 2004 this sequence version replaced XM_234551.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY603424.1, BC089874.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1550
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..1550
                     /gene="Slc25a47"
                     /gene_synonym="Hdmcp; Slc24a47"
                     /note="solute carrier family 25, member 47"
                     /db_xref="GeneID:299316"
                     /db_xref="RGD:1303247"
     exon            1..66
                     /gene="Slc25a47"
                     /gene_synonym="Hdmcp; Slc24a47"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..971
                     /gene="Slc25a47"
                     /gene_synonym="Hdmcp; Slc24a47"
                     /note="hepatocellular carcinoma down-regulated
                     mitochondrial carrier homolog; mitochondrial
                     hepatocellular carcinoma-downregulated carrier protein;
                     mitochondrial NAD(+) transporter SLC25A47"
                     /codon_start=1
                     /product="solute carrier family 25 member 47"
                     /protein_id="NP_001001509.1"
                     /db_xref="GeneID:299316"
                     /db_xref="RGD:1303247"
                     /translation="MDFVAGAIGGVCGVAVGYPLDTVKVKIQTEAKYTSIWHCVRDTY
                     RQERLWGFYRGLSLPVCTVSLVSSVSFGTYHHCLAHICRFRYGSTDVKPTKADITLSG
                     CASGLVRVFLTSPTEVAKVRLQTQAQSQTQQRRPSASWTSVAPALCPAPTACLEPRPK
                     YSGPLHCLVTVAREEGLRGLYKGSSALLLREGHSFATYFLSYAVLSEWLTPAGQSQPD
                     VLGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQQRYRGLLHCVVTSVREEGPRVL
                     FKGLALNCCRAFPVNMVVFVAYEAVLRLTQGLLT"
     exon            67..110
                     /gene="Slc25a47"
                     /gene_synonym="Hdmcp; Slc24a47"
                     /inference="alignment:Splign:2.1.0"
     exon            111..182
                     /gene="Slc25a47"
                     /gene_synonym="Hdmcp; Slc24a47"
                     /inference="alignment:Splign:2.1.0"
     exon            183..365
                     /gene="Slc25a47"
                     /gene_synonym="Hdmcp; Slc24a47"
                     /inference="alignment:Splign:2.1.0"
     exon            366..690
                     /gene="Slc25a47"
                     /gene_synonym="Hdmcp; Slc24a47"
                     /inference="alignment:Splign:2.1.0"
     exon            691..1550
                     /gene="Slc25a47"
                     /gene_synonym="Hdmcp; Slc24a47"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagcaagacc agagcccttc ttgttgccta cactgtccat ggattttgtt gctggggcca
       61 ttggaggagt ctgcggtgtt gctgtgggct accctctgga tacagtgaag gtcaaaatcc
      121 agactgaggc caagtacaca agcatctggc actgtgtccg ggacacatat cgtcaagagc
      181 ggctgtgggg attctacaga ggcctctcac tgcctgtgtg caccgtgtcc ctggtgtcat
      241 ctgtatcctt cggtacctac caccactgcc tggcccacat ttgccgcttc cggtacggca
      301 gcacggacgt caagcccacc aaggctgaca tcacactctc aggatgcgcc tctggccttg
      361 tccgggtgtt cctgacgtca cccactgagg tggccaaagt ccgcctgcag acacaggccc
      421 aatctcagac acagcagcgg cgaccctcgg cctcctggac atctgtggct cccgctttgt
      481 gtccagcacc cactgcttgc ctggagccca ggcctaagta cagtgggcca ctacattgtt
      541 tagtcacagt ggcccgagag gagggtctgc gcggactcta caagggcagc tcggctctac
      601 tccttcgtga aggccactcc tttgccacct actttctctc ctatgctgtg ctctcggagt
      661 ggctcacccc tgctggccag agtcagccag atgtcctagg tgtgctggtg gctggaggct
      721 gtgccggggt cctggcctgg gctgtggcta cgcccatgga cgttatcaag tcccgcctgc
      781 aggcggatgg gcagggccag cagcgctacc ggggcctcct gcactgtgtg gtgaccagcg
      841 tgcgggagga gggtcccaga gtgctcttca agggactggc actcaactgc tgccgcgcct
      901 ttcctgtcaa catggtggtc ttcgtggctt atgaggctgt gctgaggctc actcagggcc
      961 tgctcacata ggcactggtc agcagcatcc acgttacaca gcagccggag gcaagctcag
     1021 gatcccacag gactgtcacc cgaacagcag agggccttct gtgctgtgac ttaggggagg
     1081 cccgagttta gccagcccag tcgctgacca cagtcaggga gtttcatctg ccatctgctt
     1141 ggtggccatg agtcaggatg gtgtgagtct tcttgaggac acgtgtgtgt cacttgggag
     1201 tcatctgtca tcgaacaact gttcattcct gttggtacag ccatgcccac actgatttca
     1261 gagcattccc ttgccaaccc ctaaccccag ttccactcaa cattcaccga ttcacactgt
     1321 ccccttagag ggaggcttgg gacaagacag caagctggtt acatctggct acaggctggg
     1381 ctggtcccat cctaggctgc tcgagagagc ccacgttctc actgacccaa ggaatcggtg
     1441 cagggtatca ccatcaaagt gccatactgc ctgcaggtgc tgtgccggtc acatgaaggt
     1501 cctggaacct ggtccaggac tggctgttaa taaatgtttc tgtgcttgct
//
