LOCUS       NM_001173334            2313 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 25 member 32 (Slc25a32),
            mRNA.
ACCESSION   NM_001173334 XM_001061863 XM_235359
VERSION     NM_001173334.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Kim,J., Lei,Y., Guo,J., Kim,S.E., Wlodarczyk,B.J., Cabrera,R.M.,
            Lin,Y.L., Nilsson,T.K., Zhang,T., Ren,A., Wang,L., Yuan,Z.,
            Zheng,Y.F., Wang,H.Y. and Finnell,R.H.
  TITLE     Formate rescues neural tube defects caused by mutations in Slc25a32
  JOURNAL   Proc Natl Acad Sci U S A 115 (18), 4690-4695 (2018)
   PUBMED   29666258
REFERENCE   2  (bases 1 to 2313)
  AUTHORS   Biswas,A., Senthilkumar,S.R. and Said,H.M.
  TITLE     Effect of chronic alcohol exposure on folate uptake by liver
            mitochondria
  JOURNAL   Am J Physiol Cell Physiol 302 (1), C203-C209 (2012)
   PUBMED   21956163
REFERENCE   3  (bases 1 to 2313)
  AUTHORS   Stover,P.J. and Field,M.S.
  TITLE     Trafficking of intracellular folates
  JOURNAL   Adv Nutr 2 (4), 325-331 (2011)
   PUBMED   22332074
  REMARK    Review article
REFERENCE   4  (bases 1 to 2313)
  AUTHORS   Spaan,A.N., Ijlst,L., van Roermund,C.W., Wijburg,F.A., Wanders,R.J.
            and Waterham,H.R.
  TITLE     Identification of the human mitochondrial FAD transporter and its
            potential role in multiple acyl-CoA dehydrogenase deficiency
  JOURNAL   Mol Genet Metab 86 (4), 441-447 (2005)
   PUBMED   16165386
REFERENCE   5  (bases 1 to 2313)
  AUTHORS   McCarthy,E.A., Titus,S.A., Taylor,S.M., Jackson-Cook,C. and
            Moran,R.G.
  TITLE     A mutation inactivating the mitochondrial inner membrane folate
            transporter creates a glycine requirement for survival of chinese
            hamster cells
  JOURNAL   J Biol Chem 279 (32), 33829-33836 (2004)
   PUBMED   15140890
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001173334.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166530.1, SRR22582416.655848.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-331               JAXUCZ010000007.1  72045295-72045625   c
            332-482             JAXUCZ010000007.1  72039081-72039231   c
            483-568             JAXUCZ010000007.1  72035715-72035800   c
            569-729             JAXUCZ010000007.1  72033895-72034055   c
            730-843             JAXUCZ010000007.1  72030971-72031084   c
            844-989             JAXUCZ010000007.1  72030554-72030699   c
            990-2313            JAXUCZ010000007.1  72027857-72029180   c
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q31"
     gene            1..2313
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /note="solute carrier family 25 member 32"
                     /db_xref="GeneID:315023"
                     /db_xref="RGD:1565789"
     exon            1..331
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /inference="alignment:Splign:2.1.0"
     CDS             178..1128
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /note="mitochondrial folate transporter/carrier; solute
                     carrier family 25 (mitochondrial folate carrier), member
                     32"
                     /codon_start=1
                     /product="solute carrier family 25 member 32"
                     /protein_id="NP_001166805.1"
                     /db_xref="GeneID:315023"
                     /db_xref="RGD:1565789"
                     /translation="MTSQGQSAAGSAAWSAVFRHVRYENLVAGVSGGVLSNLALHPLD
                     LVKIRFAVSDGLEVRPKYKGILHCLATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFF
                     YNAIKSYKTEGRAEQLEALEYLISAAEAGAMTLCITNPLWVTKTRLMLQYGGVVNPSQ
                     RQYKGMIDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYEVLKLKYNKHINKLP
                     EAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTDVITKTWRKEGIG
                     GFYKGIAPNLIRVTPACCITFVVYENVSHFLYDLREKKVS"
     exon            332..482
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /inference="alignment:Splign:2.1.0"
     exon            483..568
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /inference="alignment:Splign:2.1.0"
     exon            569..729
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /inference="alignment:Splign:2.1.0"
     exon            730..843
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /inference="alignment:Splign:2.1.0"
     exon            844..989
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /inference="alignment:Splign:2.1.0"
     exon            990..2313
                     /gene="Slc25a32"
                     /gene_synonym="RGD1565789"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcggctttg ctggaactgt gccttctccg ctgcaggtcc cgggctccag ttccggaagt
       61 gggctcgcgt cgtgcggttc cgggccccgg atcgtgactg tagccacggt ggcggccact
      121 acatcacgct ccacgccggc ggcgctggac gccgtagtgt cgacgagccc ggagtccatg
      181 acaagccagg gccagtcggc ggccgggtcg gcggcatgga gtgcagtgtt ccgccacgtc
      241 cgatacgaga acctggtggc tggcgtgagt ggcggggtct tgtccaatct ggcgctgcac
      301 ccgctcgacc tcgtaaagat ccgcttcgct gtgagtgatg gactggaagt aagaccaaaa
      361 tataaaggaa ttttacattg cttggctacc atttggaaag tcgatggact acgtggactt
      421 tatcaaggag taaccccgaa tgtgtggggt gccggtttat cctggggact ctactttttc
      481 ttttacaatg ccatcaaatc atataagaca gagggaagag ctgaacagtt agaggcatta
      541 gagtacctca tctcagctgc tgaagccgga gccatgactc tctgcattac aaacccatta
      601 tgggtgacga aaactcgcct tatgttacag tatggtggtg ttgttaaccc ttcacagaga
      661 cagtataaag gaatgattga tgcacttgtg aagatatata aatatgaagg tgtacgtgga
      721 ttatacaagg gatttgtccc tggactgttt ggaacatcac atggtgccct tcagtttatg
      781 gcatatgaag tgctaaagtt gaagtacaac aaacacatca ataaattacc ggaagcccag
      841 ctgagcacag cagaatacat ctctgttgca gcactatcca aaatatttgc ggtggcagca
      901 acatacccgt atcaggttgt gagagcccgt cttcaggacc agcatgtgtc ttatggcggt
      961 gtaaccgatg tgatcacaaa gacgtggagg aaagaaggca tcggtggatt ttacaaagga
     1021 attgccccca atctaattag agtgactcca gcctgctgca tcacctttgt ggtttatgaa
     1081 aatgtctctc actttttata tgaccttaga gaaaagaaag tgagctaaaa gaagatccca
     1141 gtgtatgtgc ttgaagcagc agcaaactcc tttgtgtctg aaacacaaag ctcggaagag
     1201 tcctgcagag caacatagct cataatcgca tgtctgtggt agaagtcaca ggactgctaa
     1261 gtcatcttga cgtttctgct ctttgcttct ccgtatgtgt ggaacatggc tacctctccc
     1321 tggagtgggt accatctgat aatgttgaag ccgatagcca ctgtgaaaat gtacaagatc
     1381 ttccattttg ttgttcaggt agacgctaac ttgcaatatt tataaataat ttgatgagtg
     1441 ttcttttttt ttttttcctg aactcttttg cctggattgg ctttaaaact gaccatgtgc
     1501 aatagcgagg aactggcttc ttacaagaat gactatattt cacgggtaaa ttaaacctgg
     1561 atacttataa ataggtgtta tccaagtctt gcccattctg aatggggata tttttgttag
     1621 aaaaagtcta ttataaatgt gcttagtgtt aatccagctg gaacacacca aatacagaaa
     1681 ttggagaagt catgtatttc tctgagaaac atcaggtacc ttctgctgtt ccattgctta
     1741 attatttaca gtgaggttct agacatagac cttacatttt ggccctaaac acttatgtgt
     1801 ggttaggatg tatgcaatct gaacttccag cacccggtga cccgtcattt agcatgtgcg
     1861 gctacagatc actcatgagg aatcctggct catgtttcac agagatggaa tgtttgctgt
     1921 gagtttgttg aaaaactgaa tagaagtaaa cattccattt ccccttaatt tttagattta
     1981 tggttccaga ttccaaatgt gtctacattg gttgctcaga ttcaggatga aatacagatt
     2041 acacacatgt gtttgtggcc attactggtt tgatttctgt gtcactgtag atctccaggt
     2101 gaaaggcatc cctgaaggac gctggactga cacggactcc tctgtgcagc tggcagtgct
     2161 gtggcactag cacctgttgt ttgtaaaaaa aaaaaaaaat ctttatgatc aaagctgtat
     2221 ttaaaaggtt ctttgaaaat aagcctattt tttatatttt ggaaatggaa ttgtttttaa
     2281 aataaaaagt aaaaagataa tttatattaa caa
//
