LOCUS       NM_001106873            3231 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus solute carrier family 25 member 23 (Slc25a23),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001106873 XM_001059684 XM_217310
VERSION     NM_001106873.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3231)
  AUTHORS   Hou,T., Jian,C., Xu,J., Huang,A.Y., Xi,J., Hu,K., Wei,L., Cheng,H.
            and Wang,X.
  TITLE     Identification of EFHD1 as a novel Ca(2+) sensor for mitoflash
            activation
  JOURNAL   Cell Calcium 59 (5), 262-270 (2016)
   PUBMED   26975899
REFERENCE   2  (bases 1 to 3231)
  AUTHORS   Hoffman,N.E., Chandramoorthy,H.C., Shanmughapriya,S., Zhang,X.Q.,
            Vallem,S., Doonan,P.J., Malliankaraman,K., Guo,S., Rajan,S.,
            Elrod,J.W., Koch,W.J., Cheung,J.Y. and Madesh,M.
  TITLE     SLC25A23 augments mitochondrial Ca(2) uptake, interacts with MCU,
            and induces oxidative stress-mediated cell death
  JOURNAL   Mol Biol Cell 25 (6), 936-947 (2014)
   PUBMED   24430870
REFERENCE   3  (bases 1 to 3231)
  AUTHORS   Amigo,I., Traba,J., Gonzalez-Barroso,M.M., Rueda,C.B.,
            Fernandez,M., Rial,E., Sanchez,A., Satrustegui,J. and Del Arco,A.
  TITLE     Glucagon regulation of oxidative phosphorylation requires an
            increase in matrix adenine nucleotide content through Ca2+
            activation of the mitochondrial ATP-Mg/Pi carrier SCaMC-3
  JOURNAL   J Biol Chem 288 (11), 7791-7802 (2013)
   PUBMED   23344948
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Oct 17, 2022 this sequence version replaced NM_001106873.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.133870.1,
                                           SRR26360194.1151079.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMEA5760476 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-343               JAXUCZ010000009.1  1985023-1985365     c
            344-470             JAXUCZ010000009.1  1983618-1983744     c
            471-558             JAXUCZ010000009.1  1982435-1982522     c
            559-670             JAXUCZ010000009.1  1981389-1981500     c
            671-829             JAXUCZ010000009.1  1979062-1979220     c
            830-982             JAXUCZ010000009.1  1978825-1978977     c
            983-1090            JAXUCZ010000009.1  1978550-1978657     c
            1091-1258           JAXUCZ010000009.1  1977942-1978109     c
            1259-1409           JAXUCZ010000009.1  1973804-1973954     c
            1410-3231           JAXUCZ010000009.1  1969633-1971454     c
FEATURES             Location/Qualifiers
     source          1..3231
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..3231
                     /gene="Slc25a23"
                     /note="solute carrier family 25 member 23"
                     /db_xref="GeneID:301113"
                     /db_xref="RGD:1588586"
     exon            1..343
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..1594
                     /gene="Slc25a23"
                     /note="calcium-binding mitochondrial carrier protein
                     SCaMC-3; phosphate carrier), member 23; solute carrier
                     family 25 (mitochondrial carrier; phosphate carrier),
                     member 23"
                     /codon_start=1
                     /product="mitochondrial adenyl nucleotide antiporter
                     SLC25A23"
                     /protein_id="NP_001100343.1"
                     /db_xref="GeneID:301113"
                     /db_xref="RGD:1588586"
                     /translation="MRGGSGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGRG
                     DPDRAQQGISSDWDSDADGGLSLEEFTQYLQEREQRLLLMFHSLDRNQDGHIDVSEIQ
                     QSFRALGFSISMEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHST
                     VLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASK
                     SNRLNILGGLRNMVQEGGLLSLWRGNGINVLKIAPESAIKFMAYEQIKRAICGQQETL
                     HVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFY
                     RGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESANPGILVLLACGTISSTCGQIA
                     SYPLALVRTRMQAQASIEGGPQVSMVGLLRHILSQEGVWGLYRGIAPNFMKVIPAVSI
                     SYVVYENMKQALGVTSR"
     exon            344..470
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     exon            471..558
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     exon            559..670
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     exon            671..829
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     exon            830..982
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1090
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1258
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1409
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..3231
                     /gene="Slc25a23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctggcgcggg cggggacgac tagcatttat cacttccagc aagtgccaga gctcagcccc
       61 gcagcgaaga ggctgcagtg cgagtgggtg cagaagctgg ccctgtgggg accccggggg
      121 ggagggggag ccggaaagcc cccgccgagg ccgtcgctgc ggggcctccc ctcccccccg
      181 ggcgggcgcc atgcgggggg gctcaggcga cgcggagcgg cggcagcgct ggggtcgcct
      241 gttcgaggaa ctagacagca acaaggacgg ccgcgtggac gtgcacgagt tgcgccaggg
      301 gctggctagg ctgggaaggg gcgatccgga ccgtgcacag cagggcatct cctctgactg
      361 ggacagtgat gcagatggcg gcctcagcct ggaggagttt actcagtacc tgcaggaacg
      421 ggagcagcgc cttctgctca tgtttcacag ccttgaccgg aaccaggatg gtcacatcga
      481 tgtctctgag attcagcaga gcttccgtgc actgggtttc tccatctcaa tggagcaagc
      541 agagaaaatc ctacacagca tggaccgtga tggcaccatg accattgatt ggcaggaatg
      601 gcgagaccac tttctgctgc actctctgga gaatgtggag gatgtccttt atttctggaa
      661 gcattcaaca gtcctggaca ttggtgaatg cctaacggtg cctgatgagt tctccaagca
      721 agagaaactt acaggcatgt ggtggaagca actggtggcc ggtgcagtgg ctggcgctgt
      781 gtcacggaca ggcacagctc ctctggaccg actcaaggta ttcatgcagg tccatgcctc
      841 aaagtccaac cggctcaaca tcctaggggg cctgagaaac atggttcaag aagggggcct
      901 cttgtccctc tggcggggca acggcatcaa cgtgctcaag atcgcccctg agtctgccat
      961 taaattcatg gcttatgaac agatcaagcg ggccatctgc gggcagcaag agacactgca
     1021 cgttcaggag cgcttcgtgg ctggctccct ggccggggcc acagctcaaa ccatcatata
     1081 ccccatggag gtactaaaga ctcggctgac tctacgcaga actggccagt acaaggggct
     1141 cctggactgt gcaaggcgaa tcttagagcg tgaagggcca cgcgccttct accgtggcta
     1201 cctgcctaat gtgctgggca tcattcccta tgcaggaatc gacctagctg tctacgagac
     1261 cctgaagaat cgctggcttc agcagtacag ccacgaatca gctaacccag gcattcttgt
     1321 gctcctggcc tgtggcacca tctccagcac ctgtggccag attgccagtt accctctggc
     1381 actggtccgt acccgaatgc aggcccaagc ctccattgag ggtggcccgc aggtctccat
     1441 ggtgggtctg cttcgacaca tcctatccca ggagggtgta tggggcctct accggggcat
     1501 tgcccccaac ttcatgaagg tcattccagc tgtgagcatc tcctacgtgg tctacgagaa
     1561 catgaagcag gctctggggg tcacatccag gtgagggact gggagcctgt ccccccaaga
     1621 ttctctcatc ttcatcatgg catcccctac gctgatgtct tcaaccaccg gagactggtg
     1681 gcctgaccag tggatcctaa tccctacccc aaggcactgg accccagtac ccaaatccca
     1741 catcctgtgt cctgaccacg gtaccactct tcagccacag gatcccatga cttgatcctc
     1801 aacttcacaa cccgaccccc aagcccaaca acccctggac cccacatatc tgcactcttg
     1861 acacttgaaa tgtaaaacta cccataccct ggccccaagc ctctcgaccc tgctcatgca
     1921 caccccaaag ctgaatcctg cttttccctg ccccactggg ttctgggcct ccctgtgcag
     1981 cagcaggtgg tcccagtgcc ccaagcatgg gggcactcat ccacataccc catagaccag
     2041 acctcagagc ctcaggcacc agacccagtg ccctaatggc acactggacc agagatcccc
     2101 aaacttgctg ctgagttccc tgtcatctgt ctcatagctc agccacaggg tcctgacagg
     2161 gcaataccaa gatcctgggc tctgccactg gtccctggat ccctgggcaa tgcatttccc
     2221 tgtttggggt tccatatcct cccattttta ctgctgggtc tacatttcca gcaccaccct
     2281 tgaggtctct caccactgga ccccaagtcc cgatccactg gatcctggct cctggaagca
     2341 tgggaaagct ccaggcctct catgtggatc ccacatgctc cagctgctaa attccagatc
     2401 ccagattcct tcaagccctt ctgtggacaa catccacaga aggccaaact cccagacacc
     2461 tctctatccc atctcctaca ccccaatcgt cactccccat gtctagctcc cagtagccca
     2521 gtgacagtat cccataaccc agacacacac tggagctgat tcccacggca tgagagcctt
     2581 ctggaagctc agacaccaga ccagtggctc cctaccaggc ggtaagggat cggacatatg
     2641 aatgctggat tgcacctcag ctaggacaca cctcccctcc caccactccc caaagtcact
     2701 tcattccctg tcccctactc tctccaatgt cttccacatt ccctgccttc ccaccaggcc
     2761 agtcactccc agaacccagg ccactctggg agggtccagt cttgttcatg gggatcagga
     2821 acaaaaccaa ggggaccatc tgcctcccac actgccagcc ctgcttgggc ctcagaaagt
     2881 cacaatcaag gaccaacaca caacatcctt cctgaaaccc agcatccaat atgcaaatta
     2941 agtatccccg agctgactcg gagttttgtt tttttgattt tttggtttta ccagagaaca
     3001 aagtcccctg gctcccacca catccccata ccctccgcac ttcaagttag attccaagct
     3061 tagaactggg agctctccgc tccgcctccc agtctttagg agacctctca tcaaagaact
     3121 gagaggaaaa ctgggatgct gggggacacg gtttccacca acctacacca agtcctacct
     3181 ccctgcccat gtgtgtcatt tcaagaaaaa aataaatttt ctaagctctt a
//
