LOCUS       NM_138908               2701 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 22, member 25 (Slc22a25),
            mRNA.
ACCESSION   NM_138908
VERSION     NM_138908.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2701)
  AUTHORS   Yokoyama,H., Anzai,N., Ljubojevic,M., Ohtsu,N., Sakata,T.,
            Miyazaki,H., Nonoguchi,H., Islam,R., Onozato,M., Tojo,A.,
            Tomita,K., Kanai,Y., Igarashi,T., Sabolic,I. and Endou,H.
  TITLE     Functional and immunochemical characterization of a novel organic
            anion transporter Oat8 (Slc22a9) in rat renal collecting duct
  JOURNAL   Cell Physiol Biochem 21 (4), 269-278 (2008)
   PUBMED   18441515
  REMARK    GeneRIF: Oat8 was identified as the n58 kDa protein that in the
            collecting duct colocalized with the V-ATPase in plasma membranes
            and intracellular vesicles in various subtypes of intercalated
            cells
REFERENCE   2  (bases 1 to 2701)
  AUTHORS   Shin,H.J., Anzai,N., Enomoto,A., He,X., Kim,D.K., Endou,H. and
            Kanai,Y.
  TITLE     Novel liver-specific organic anion transporter OAT7 that operates
            the exchange of sulfate conjugates for short chain fatty acid
            butyrate
  JOURNAL   Hepatology 45 (4), 1046-1055 (2007)
   PUBMED   17393504
REFERENCE   3  (bases 1 to 2701)
  AUTHORS   Youngblood,G.L. and Sweet,D.H.
  TITLE     Identification and functional assessment of the novel murine
            organic anion transporter Oat5 (Slc22a19) expressed in kidney
  JOURNAL   Am J Physiol Renal Physiol 287 (2), F236-F244 (2004)
   PUBMED   15068970
REFERENCE   4  (bases 1 to 2701)
  AUTHORS   Schomig,E., Spitzenberger,F., Engelhardt,M., Martel,F., Ording,N.
            and Grundemann,D.
  TITLE     Molecular cloning and characterization of two novel transport
            proteins from rat kidney
  JOURNAL   FEBS Lett 425 (1), 79-86 (1998)
   PUBMED   9541011
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 2, 2020 this sequence version replaced NM_138908.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Y09945.1, SRR26643287.3063.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-604               JAXUCZ010000001.1  214861737-214862340 c
            605-708             JAXUCZ010000001.1  214860574-214860677 c
            709-863             JAXUCZ010000001.1  214858011-214858165 c
            864-1032            JAXUCZ010000001.1  214857685-214857853 c
            1033-1156           JAXUCZ010000001.1  214842146-214842269 c
            1157-1272           JAXUCZ010000001.1  214831171-214831286 c
            1273-1487           JAXUCZ010000001.1  214773854-214774068 c
            1488-1596           JAXUCZ010000001.1  214771672-214771780 c
            1597-1800           JAXUCZ010000001.1  214769976-214770179 c
            1801-2701           JAXUCZ010000001.1  214767837-214768737 c
FEATURES             Location/Qualifiers
     source          1..2701
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2701
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /note="solute carrier family 22, member 25"
                     /db_xref="GeneID:192273"
                     /db_xref="RGD:621104"
     exon            1..604
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..1861
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /note="solute carrier family 22 (organic anion/cation
                     transporter), member 9; integral membrane transport UST1r;
                     putative integral membrane transport UST1r"
                     /codon_start=1
                     /product="solute carrier family 22 member 24"
                     /protein_id="NP_620263.1"
                     /db_xref="GeneID:192273"
                     /db_xref="RGD:621104"
                     /translation="MAFQDLLNQVGSLGRFQILQMTFILIFNIIISPHSLLENFTAVI
                     PNHRCWVPILDNDTVSGNDNGNLSQDDLLRVSIPLDSDLRPEKCRRFVQPQWDLLHLN
                     GTFSSVTEPDTEPCVDGWVYDQSTFLSTIITEWDLVCESQSLDSIAKFLFLTGILVGN
                     ILYGPLTDRFGRRLILICASLQMAVTETCAAFAPTFLIYCSLRFLAGISFSTVLTNSA
                     LLIIEWTRPKFQALATGLLLCAGAIGQTVLAGLAFTVRNWHHLHLAMSVPIFFLLVPT
                     RWLSESARWLIMTNKLQKGLKELIKVAHINGMKNSTDVLTIEVVRTIMKEELEASQTK
                     SSLWDLFRTPNLRKRICLLSLVRFVVWLSVIGLLINFQHLRINVFLLQCLLGIITIPA
                     NLVGIFLVNHLGRRISQLFIISLFGISILAIIFVPQEMQILRMVLATFGGVFSFVSVS
                     SALVHANELLPTIIRATALGVIGIAGSTGAALSPLFMILRTYSDSLPWIIYGVLSFLG
                     GLVVLLLPETKNQPLPDSIQDVENEGRASRQGKQNDTLIKVTQF"
     exon            605..708
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     exon            709..863
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     exon            864..1032
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1156
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1272
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1487
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..1596
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1800
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..2701
                     /gene="Slc22a25"
                     /gene_synonym="Slc22a9; Ust1; Ust1r"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttaaagaaa gtagcttcct tatataacac ccaagtcttt aggtgaaagc tgttctatgg
       61 ccttgatgca gaagggaaag ggaacatatt aagaaggggt caggatctgg tctatagtga
      121 aaaagaactt gttaaatcct ttgggctcac ataagagcaa tttatttttg tgccttcctt
      181 tggacatagt aattagtcct agatggcctt tcaggacctc ctgaatcaag ttggcagcct
      241 ggggaggttc cagatccttc agatgacttt cattttgatc ttcaacataa taatttctcc
      301 tcattctcta ttggagaact tcacagcagt cattcccaat catcgctgct gggtccccat
      361 cctcgacaat gacactgtct ctggtaatga caatgggaac ctgagccaag atgacctcct
      421 gagggtctct atccccctgg actccgatct gagaccagag aagtgtcgtc gctttgtcca
      481 accacagtgg gatctccttc atctaaacgg taccttttcc agtgtgacag agccagacac
      541 agagccctgt gtggatggct gggtgtatga ccaaagcacc tttctttcca ccattattac
      601 cgagtgggac ctggtgtgtg aatctcagtc actggattca atagctaagt ttctattctt
      661 gactggtatc ttagtaggaa atatcctata tggcccctta acagacaggt ttgggaggag
      721 gttaatcctt atatgtgcct cactgcaaat ggccgtcact gaaacctgtg cagcttttgc
      781 tcccaccttt ctcatctact gctcactacg attcctggca gggatttcct tctcaaccgt
      841 tttgaccaat agtgccttgc tcattataga atggacaagg cctaaattcc aagccttggc
      901 aacaggactg ctattatgtg ctggagcaat tggacagaca gtattggcag gcctggcttt
      961 tactgtgcga aactggcacc acctccatct ggcaatgtct gtaccaatat ttttcttact
     1021 tgtacccaca aggtggctgt cagagtcagc gcggtggctg attatgacca acaaactcca
     1081 gaagggctta aaagaactta taaaagttgc acacataaat ggaatgaaga attcaacaga
     1141 tgtcctaacc attgaggttg tgagaacaat catgaaggag gagctggagg cctcacagac
     1201 aaaatcttcc ctgtgggact tgttccgtac acctaacttg cgtaagcgga tatgccttct
     1261 gtcccttgtg agatttgtgg tatggttatc tgtgattggt ttactgatca acttccagca
     1321 cctaaggatc aatgtcttcc tattgcagtg tcttcttggt ataatcacca ttccagccaa
     1381 tttagttgga atttttttgg tgaatcactt gggtcgcaga ataagtcaac tatttatcat
     1441 atccctgttt ggaatttcca ttttggccat aatatttgtg cctcaagaaa tgcagatcct
     1501 gcgcatggtt ttggcaactt ttggaggagt attttctttt gtctctgtta gcagtgctct
     1561 tgtgcatgca aatgagctac ttcccactat aatcagggca actgctttag gagtcattgg
     1621 aattgctggt agtactgggg cagccctgtc tcctctgttt atgatcctta ggacatactc
     1681 tgactccttg ccctggatca tctatggagt cctttccttc cttggtggcc ttgttgtcct
     1741 tctcctccct gagaccaaga atcagcctct gcctgactcc atacaggatg tggaaaatga
     1801 aggaagagcc tccagacaag gaaagcagaa tgatactctc atcaaagtga cacagtttta
     1861 agagactcca agagctgaaa tctgataaag gagcaagata agaaaactgt cactcagatt
     1921 tatgatggcc caggttcact ctagatacag caaaattcct tatcaagtaa cgatatagca
     1981 aaaattttgt attacattta aaatttccac attcaactga tacttaaatt atctcaataa
     2041 caaaattaaa ggaaaacaac acagtgaaat aaatcttcag agttttaata gacacttatg
     2101 aagtttccac aaaggatgtg gatgaacctt cttcccatta ttgtgacata atgcttggga
     2161 aaattaaaaa tggataattt attgtgaaat tcccattagt ttcatcccac tgctgttgcg
     2221 ataatctcct gtgtactatg tagatgaccg tctttgtatt attcaagtgc tgatctcagt
     2281 atcagcagag atttaagtat agctggactt tggtattatt atttttatga agcatcacca
     2341 gtctcagtat tctgtaaaca tcttctctat caccttctga ttggtataat aaaaaggcga
     2401 atggcctatg ccagggcagg agaggaaagg tagatatttc atttgttgag agatagaaac
     2461 tctgggaaag agttgatgat gaaattgatc agcgaaatgt gctagaagcc tcagaatttt
     2521 gtaaaaaaca ccatgttaac agtaaagatt tgaagaaaga tttttctaac aagcccaagt
     2581 tctgggcaac aagcccagaa aattataagg aaatgtccta cttgttcttt gtataaccta
     2641 acaccatcac ttgcagaaag taacccaaag atacccaaag aaataaaatt ttacaagtgt
     2701 a
//
