LOCUS       NM_001013947            1855 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 22 member 22 (Slc22a22),
            mRNA.
ACCESSION   NM_001013947 XM_235317
VERSION     NM_001013947.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Hatano,R., Onoe,K., Obara,M., Matsubara,M., Kanai,Y., Muto,S. and
            Asano,S.
  TITLE     Sex hormones induce a gender-related difference in renal expression
            of a novel prostaglandin transporter, OAT-PG, influencing basal
            PGE2 concentration
  JOURNAL   Am J Physiol Renal Physiol 302 (3), F342-F349 (2012)
   PUBMED   22031854
  REMARK    GeneRIF: OAT-PG is involved in local PGE(2) clearance in the renal
            cortex.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081982.1.
            
            [WARNING] On May 10, 2024 this sequence was replaced by
            NM_001013947.2.
            
            On Apr 20, 2005 this sequence version replaced XM_235317.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081982.1, AB559554.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q33"
     gene            1..1855
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /note="solute carrier family 22 member 22"
                     /db_xref="GeneID:299944"
                     /db_xref="RGD:1304605"
     exon            1..37
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            38..456
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1722
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /note="prostaglandin transporter OAT-PG; solute carrier
                     family 22 (organic cation transporter), member 22"
                     /codon_start=1
                     /product="solute carrier family 22 member 22"
                     /protein_id="NP_001013969.1"
                     /db_xref="GeneID:299944"
                     /db_xref="RGD:1304605"
                     /translation="MAFDEILHHVGDRGRFQIWMIVVLNILSMVSSLHDVIENFTAAI
                     PAHHCSVNLLDTSRSEISMAMNLTTEAMMKVSIPMGPNQKPEQCRRFRHPQWQFIDSN
                     ISTSNSTELETEPCLDGWTYDHSVFTSTIVTEWDLVCDFQSFKYYAQATSLAGHFVAA
                     PFCGIISDRFGRKPLLMYCSLAYGILGTCCAFVPNFSLYCVLRFLSSASASTVGMNCL
                     ILVLEETSVQWHATVIVLSGLFSSTGLAGLGGLAYVLSDWHLIQLTSALPYFIFFILF
                     CWVPESARWLMITGKTDQALKELQRIASINGKKDIAQNLTTEDLRSKVKEDVCSTVKH
                     FSIKDIIINPMIRKIVLCYSSVLFAELFSIFGLLLDVHMLGKNIFVTQILLGVIDIPS
                     KSLTYFILRNVRRRPLIAFLLFATGGCITITMFLSEDMYVLRLAIFILGKGCFAAFIS
                     INTAYCNELSPVPLRSTLNGIYISVARLASVLSALTLVTRKYFVLLPMIFCGVLPIVA
                     TINIYFLPETFNHPITDTIKDMEKRNRLMSKNISEKEGQDFLETTNC"
     exon            457..560
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            561..715
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            716..884
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1008
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1124
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1339
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..1448
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1652
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1831
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg; RGD1304605"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtgatttg gctgtgtgca acagaagtcc tatacagcat ttgcaagaat cgccatggct
       61 tttgatgaaa ttctacatca tgtaggtgac cgtggaagat ttcagatttg gatgattgtt
      121 gttctcaaca ttttatctat ggtgtcatct cttcatgatg tcatagagaa ttttacagca
      181 gccattcctg ctcatcactg cagtgtaaac cttcttgaca cgtcaagatc tgaaattagt
      241 atggccatga acttgactac tgaagctatg atgaaggtct ccatcccaat gggcccaaat
      301 cagaaacctg aacaatgccg acgctttcgg caccctcaat ggcaattcat agattccaat
      361 atatcaactt ctaacagcac tgagctagag actgagcctt gcctagatgg atggacgtat
      421 gaccacagtg tctttacttc taccattgtc actgagtggg atttagtatg tgattttcag
      481 tcattcaaat actatgcaca agccacctct ttggcagggc attttgtggc tgctcctttc
      541 tgtggcatta tttctgatag gtttggaaga aagccattgt tgatgtattg ttccttagcc
      601 tatgggattt tggggacctg ctgtgccttt gtccccaatt tctccttgta ctgtgttttg
      661 agattcctgt catctgcctc tgcaagtact gttgggatga actgtcttat tcttgtttta
      721 gaagaaacat cggtacagtg gcacgccaca gtcatagtac tcagtggact gttcagcagt
      781 actggcctgg ctgggcttgg gggactagca tatgtgcttt cagattggca cttaattcaa
      841 cttacatctg ccttgcccta cttcatcttt tttattttgt tctgctgggt gccagaatca
      901 gcccggtggc tcatgattac aggaaaaaca gatcaagcat tgaaggaact ccagagaatt
      961 gcctccatca atgggaagaa agacattgca caaaatctaa ccactgagga cttgcgatcc
     1021 aaagttaagg aagatgtgtg ttcaactgta aagcatttca gtataaagga catcattatt
     1081 aatcccatga tacgtaaaat cgtgctttgt tattccagtg tactttttgc agaacttttt
     1141 agcatttttg gcctcttgtt ggatgttcac atgttgggaa agaacatatt cgtgacccag
     1201 attctcctag gagtgataga catacccagt aaatcactca catattttat attaagaaat
     1261 gtaagacgtc gtcctttaat tgcttttttg ctctttgcaa ctggaggttg tattaccatc
     1321 accatgtttc tctctgaaga catgtatgtc ttgcgtcttg ctattttcat tttgggaaaa
     1381 ggatgttttg cagctttcat ttctataaac acagcctact gcaatgaact ttcaccagta
     1441 ccactcaggt caactctaaa tggtatttat atatctgttg ctcgattagc atcagtcctg
     1501 tctgcactaa cacttgttac tagaaagtat tttgtacttc ttcccatgat tttctgtgga
     1561 gtcctaccca tagtggcaac aatcaacatc tactttctgc cagagacctt taatcatcca
     1621 attactgaca ctatcaagga tatggagaaa aggaacagat tgatgagcaa aaacatcagt
     1681 gaaaaagaag gacaagactt tttagaaact accaactgct aaagaagcca agatccacag
     1741 ggtttcatcc atgcaaatcc tctttattct gttctgtacc ctagagactt tactcattga
     1801 ttggcattca tgaataaact tattaaatga aaaaaaaaaa aaaaaaaaaa aaaaa
//
