LOCUS       NM_001126285            2029 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 22 member 13 (Slc22a13),
            mRNA.
ACCESSION   NM_001126285 XM_001077418 XM_236685
VERSION     NM_001126285.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2029)
  AUTHORS   AbuAli,G., Chaisaklert,W., Stelloo,E., Pazarentzos,E., Hwang,M.S.,
            Qize,D., Harding,S.V., Al-Rubaish,A., Alzahrani,A.J., Al-Ali,A.,
            Sanders,T.A., Aboagye,E.O. and Grimm,S.
  TITLE     The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for
            tumour-specific apoptosis
  JOURNAL   Oncogene 34 (13), 1718-1728 (2015)
   PUBMED   24769897
REFERENCE   2  (bases 1 to 2029)
  AUTHORS   Nikiforov,A., Kulikova,V. and Ziegler,M.
  TITLE     The human NAD metabolome: Functions, metabolism and
            compartmentalization
  JOURNAL   Crit Rev Biochem Mol Biol 50 (4), 284-297 (2015)
   PUBMED   25837229
  REMARK    Review article
REFERENCE   3  (bases 1 to 2029)
  AUTHORS   Schulz,C., Fork,C., Bauer,T., Golz,S., Geerts,A., Schomig,E. and
            Grundemann,D.
  TITLE     SLC22A13 catalyses unidirectional efflux of aspartate and glutamate
            at the basolateral membrane of type A intercalated cells in the
            renal collecting duct
  JOURNAL   Biochem J 457 (2), 243-251 (2014)
   PUBMED   24147638
  REMARK    GeneRIF: Expression of SLC22A13 in basolateral membrane of renal
            collecting duct stimulates efflux of aspartate and glutamate.
REFERENCE   4  (bases 1 to 2029)
  AUTHORS   Irshad,S., Mahul-Mellier,A.L., Kassouf,N., Lemarie,A. and Grimm,S.
  TITLE     Isolation of ORCTL3 in a novel genetic screen for tumor-specific
            apoptosis inducers
  JOURNAL   Cell Death Differ 16 (6), 890-898 (2009)
   PUBMED   19282870
REFERENCE   5  (bases 1 to 2029)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 2029)
  AUTHORS   Bahn,A., Hagos,Y., Reuter,S., Balen,D., Brzica,H., Krick,W.,
            Burckhardt,B.C., Sabolic,I. and Burckhardt,G.
  TITLE     Identification of a new urate and high affinity nicotinate
            transporter, hOAT10 (SLC22A13)
  JOURNAL   J Biol Chem 283 (24), 16332-16341 (2008)
   PUBMED   18411268
  REMARK    GeneRIF: SLC22A13 is a new urate and high affinity nicotinate
            transporter
REFERENCE   7  (bases 1 to 2029)
  AUTHORS   Nishiwaki,T., Daigo,Y., Tamari,M., Fujii,Y. and Nakamura,Y.
  TITLE     Molecular cloning, mapping, and characterization of two novel human
            genes, ORCTL3 and ORCTL4, bearing homology to organic-cation
            transporters
  JOURNAL   Cytogenet Cell Genet 83 (3-4), 251-255 (1998)
   PUBMED   10072596
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166511.1.
            
            On or before May 7, 2008 this sequence version replaced
            XM_001077418.1, XM_236685.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166511.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132267,
                                           SAMD00132280 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2029
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..2029
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /note="solute carrier family 22 member 13"
                     /db_xref="GeneID:316062"
                     /db_xref="RGD:1306840"
     exon            1..404
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..1682
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /note="solute carrier family 22 (organic cation
                     transporter), member 13; organic anion transporter 10;
                     organic cation transporter-like 3; solute carrier family
                     22 (organic anion transporter), member 13; solute carrier
                     family 22 (organic anion/urate transporter), member 13"
                     /codon_start=1
                     /product="solute carrier family 22 member 13"
                     /protein_id="NP_001119757.1"
                     /db_xref="GeneID:316062"
                     /db_xref="RGD:1306840"
                     /translation="MAQFAQVMAEVGDFGRFQVRLTILMGIPNFLSAFFVFSQVFMVL
                     DEAHYCSVSWVKNHTFNLSAAEQLAVSIPNDTAGRPESCLMFRPPPDNASLEDILSHR
                     FNETQACDSGWDYPENRPPSLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCD
                     WIGRRPSLLMQLLLSGIASMATAFVSSFELYMTLRFALATANAGFLLSSNVLLSEWVG
                     TSRRTRAMVLAQSNFALGLMALAGLAYGVRNWRLLQIIGTTPIFLLVFYFWVLPESPR
                     WLLSQGRTEEAKQLVQKAALVNGRPLASELLNQLVPEKTGPSGNALDLFRHPQLRKVT
                     LILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIFGVVEVPARLSSIPMMEKLGRKWS
                     QLCTLTLAGVMCVIIIFIPGDLPTVATALAVVGKFASSAAFTISYVYTAELLPTIIRQ
                     TGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPETRGQTLK
                     DTLQDLEQGQPPRSYKTAPQRKDVEASGRTSSARVAVVRSSYF"
     exon            405..508
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            509..663
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            664..832
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            833..953
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1048
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1263
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1372
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1373..1588
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..2000
                     /gene="Slc22a13"
                     /gene_synonym="OAT10; ORCTL-3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctccactaa gcagtgataa gcagacatgg cccagtttgc acaggtcatg gctgaagtgg
       61 gcgattttgg tcgcttccag gtgcggttga ccatcctgat gggcatcccc aatttcctgt
      121 ctgcattctt cgtgtttagc caggtcttca tggtccttga tgaggctcac tactgttcag
      181 tgtcctgggt taagaaccac actttcaacc taagtgctgc tgagcagctg gctgtcagca
      241 tacccaacga cacggcaggc aggcccgagt cctgcctcat gttccggcca cctcctgaca
      301 atgccagcct ggaagacatc ctgagccacc gcttcaatga gacacaggcc tgcgactcgg
      361 gctgggacta tcctgagaac aggcctccgt ccctaaagaa cgagtttgac ctggtgtgtg
      421 agcgggagaa cctgaagagg acctcgcagt cggtgttcat ggcggggctc ctagtggggg
      481 ccctagtctt tgggcctgtc tgtgactgga ttggccgcag accctccctc ctaatgcagc
      541 tgcttctgtc aggcatcgca agtatggcta cagcctttgt gtccagcttt gagctctata
      601 tgaccctacg ctttgccttg gctactgcca acgctggatt tttactgagc agcaatgtcc
      661 tgctttcaga gtgggtggga acatcccgga ggacacgagc catggtcctg gcccagagca
      721 actttgccct tgggctgatg gcgttagcag gactggccta tggtgtccga aactggagac
      781 tccttcagat aataggcacc acacccatct tcctgcttgt cttctatttc tgggttctgc
      841 cagaatctcc acggtggctc ctctctcaag gaaggacaga ggaggccaaa cagctggtcc
      901 agaaggcagc cttggtgaac ggccggccac ttgcctctga gctcctgaac cagctggtcc
      961 ctgagaagac aggcccctcg gggaatgcct tggatctttt cagacaccct cagctcagga
     1021 aggtgactct gattctcata gctgtctggt ttgtggacag cctgctgtac tatggactcg
     1081 gcttccaagt gggggacttt ggtctggaca tctacctgac acaggtaata ttcggagtag
     1141 tggaagtacc tgcccgtctt tccagcatcc ccatgatgga gaagctgggt cggaagtgga
     1201 gccagctctg taccctgacc cttgctggtg tcatgtgtgt catcatcatc ttcatcccag
     1261 gagatcttcc cacagtggcc actgcactgg ctgtggtggg gaagtttgcc tcgtctgctg
     1321 ccttcaccat ttcctatgtg tacactgctg agctcctccc caccatcatc aggcaaacag
     1381 gcatggggtt ggtgagcatc ttctccaggg tcgggggcat catcacaccc cttgtgatgc
     1441 tgctggaaca gtaccacaag gcgattccca tgctgatctt tggcagcctc cccattgggg
     1501 caggcctact gtgtgctctg ctgcctgaga caagaggcca gaccctgaag gacaccctcc
     1561 aggacctgga gcaggggcag cccccacggt cctacaaaac tgcaccccaa agaaaagacg
     1621 tggaggcctc aggaagaacg tccagtgcca gggtggccgt tgtgagaagc tcctacttct
     1681 gactgtggtc gctaagggcc agcctatcaa aggcccagga cagcccacac catcttcctg
     1741 tttgaatggc atccgtagcg cacaggatca gaccagccgt gttcatggcc cccgctccat
     1801 actgcagaac cctgtggaag tgccagggtc cgtacccctc cctcctccac acccctgata
     1861 cacacactgc accccagtac cacagctgag tcagggcctg gatggttctt ggtcttctct
     1921 gacatctctc tgggattacg gtctccctgt tcgccctgtc tggaatactc catccccata
     1981 aagacaagga tgaaaccacg aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
