LOCUS       NM_001108973            2786 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus solute carrier family 1 member 7 (Slc1a7), mRNA.
ACCESSION   NM_001108973 XM_001066839 XM_345559
VERSION     NM_001108973.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2786)
  AUTHORS   Schneider N, Cordeiro S, Machtens JP, Braams S, Rauen T and Fahlke
            C.
  TITLE     Functional properties of the retinal glutamate transporters GLT-1c
            and EAAT5
  JOURNAL   J Biol Chem 289 (3), 1815-1824 (2014)
   PUBMED   24307171
REFERENCE   2  (bases 1 to 2786)
  AUTHORS   Lee A, Anderson AR, Stevens M, Beasley S, Barnett NL and Pow DV.
  TITLE     Excitatory amino acid transporter 5 is widely expressed in
            peripheral tissues
  JOURNAL   Eur J Histochem 57 (1), e11 (2013)
   PUBMED   23549460
  REMARK    GeneRIF: EAAT5 is a widely distributed protein. Whether it
            functions in all locations as a glutamate transporter, or mainly as
            a glutamate-gated chloride conductance, remains to be determined.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2786)
  AUTHORS   Lee A, Anderson AR, Barnett NL, Stevens MG and Pow DV.
  TITLE     Alternate splicing and expression of the glutamate transporter
            EAAT5 in the rat retina
  JOURNAL   Gene 506 (2), 283-288 (2012)
   PUBMED   22820393
  REMARK    GeneRIF: EAAT5 exists in multiple spliced forms in the rat retina
REFERENCE   4  (bases 1 to 2786)
  AUTHORS   Dalet A, Bonsacquet J, Gaboyard-Niay S, Calin-Jageman I,
            Chidavaenzi RL, Venteo S, Desmadryl G, Goldberg JM, Lysakowski A
            and Chabbert C.
  TITLE     Glutamate transporters EAAT4 and EAAT5 are expressed in vestibular
            hair cells and calyx endings
  JOURNAL   PLoS One 7 (9), e46261 (2012)
   PUBMED   23049999
REFERENCE   5  (bases 1 to 2786)
  AUTHORS   Arriza JL, Eliasof S, Kavanaugh MP and Amara SG.
  TITLE     Excitatory amino acid transporter 5, a retinal glutamate
            transporter coupled to a chloride conductance
  JOURNAL   Proc Natl Acad Sci U S A 94 (8), 4155-4160 (1997)
   PUBMED   9108121
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474008.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001066839.1, XM_345559.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN11044071
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2786
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q34"
     gene            1..2786
                     /gene="Slc1a7"
                     /note="solute carrier family 1 member 7"
                     /db_xref="GeneID:366432"
                     /db_xref="RGD:1311928"
     exon            1..377
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     CDS             213..1925
                     /gene="Slc1a7"
                     /note="EAAT5; solute carrier family 1 (glutamate
                     transporter), member 7"
                     /codon_start=1
                     /product="excitatory amino acid transporter 5"
                     /protein_id="NP_001102443.1"
                     /db_xref="GeneID:366432"
                     /db_xref="RGD:1311928"
                     /translation="MEWCQQAGLSMVLGAFLARGRAVCRHNGLLILSVLSVIVGCLLG
                     FFLRTQRLSPQEISYFQFPGELLMRMLKMLILPLVVSSLMSGLASLDAKTSSRLGILT
                     VAYYLWTTFLAVVVGIIMVSIIHPGGAAQKETTEQSGKPVMSSADALLDLVRNMFPAN
                     LVEATFKQYRTKTTPVIKSPKGAAEEAPPRGIVIYGVQEDNGSRVQNFALDLTPPPEI
                     VYKSEPGTSDGMNVLGIVIFSATMGIMLGRMGDSGTPLVSFCQCLNESVMKIVAVAGW
                     YFPFGIVFLIAGKILEMDDPKAVGKKLGFYAVTVVCGLVVHGLLILPLLYFLITRKNP
                     IVFIRGVLQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTA
                     LYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLP
                     TDDINLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFAQDMGTEKLLPCETKPV
                     TLQEIVAAQQNGCVKSVAEASELTLGPKCPHHIPVQVEQDEELATASLDHCTIEINEL
                     ETNV"
     exon            378..457
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            458..673
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            674..716
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            717..939
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1039
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1273
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1468
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1603
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1604..1706
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..2786
                     /gene="Slc1a7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggatgccccg accacgtggc ctgctctaat ttcccaggcc ctaatctgct cctcactcct
       61 aatgattcag ctggtaatag gattgtgact tccctttggg cagctgcaca gaccatggct
      121 gaaaggccgg tgataggtgc ttaggattcc gttcacctgt aagcagagag gcttgtgcct
      181 ccagcccaga cctgggccac aacctacagt gcatggaatg gtgccaacag gctgggctca
      241 gcatggtgct gggcgccttt ctggctcgag ggcgggcagt gtgtagacac aacgggctcc
      301 tcatcctgtc tgtgctgtct gtcatcgtgg gctgcctcct tggcttcttc ctcaggaccc
      361 agcgcctctc accacaggag attagctact tccagttccc tggagaactc ttgatgagga
      421 tgctgaagat gctgatccta ccactggtgg tctccagctt gatgtctggc cttgcctccc
      481 tggatgccaa gacctccagc cgcttgggca tcctcaccgt ggcatattac ctgtggacca
      541 cctttctggc tgtcgtcgtg ggcatcatca tggtctccat catccaccct ggtggtgcag
      601 cacagaagga gaccaccgaa cagagtggaa agccagtcat gagctcagcc gatgccctcc
      661 tggaccttgt ccggaacatg tttccagcca acctggtaga agccacattc aaacagtacc
      721 gcaccaaaac caccccagtt atcaagtctc ccaaaggggc tgcggaggag gcccctcccc
      781 gggggatcgt catctacggg gtccaggaag acaacggctc acgtgtgcag aactttgccc
      841 tggacctgac gcccccgcct gagattgtct ataagtcaga gcctggtacg agtgacggca
      901 tgaacgtgct aggcatcgtc atcttctcgg ccactatggg catcatgctg ggccgcatgg
      961 gtgacagcgg gacccccctg gtcagcttct gtcagtgcct taatgagtcc gtcatgaaga
     1021 tcgtggcagt ggcagggtgg tacttcccct tcggcattgt cttcctgatc gctggcaaga
     1081 tcctggagat ggatgacccc aaggctgtgg ggaagaagct gggcttctat gccgtgaccg
     1141 tggtttgtgg gctggtggtc cacggtctcc taatcctgcc cctgctgtat ttcctcatca
     1201 ccaggaagaa ccccatcgtc ttcatccgtg gcgtcctcca agctctgctc attgcactgg
     1261 ccacctcctc cagctcagcc accctgccca tcaccttcaa gtgtctgctg gagaacaacc
     1321 acatcgaccg acgcatcgct cgctttgtgc tgcccgtggg cgccaccatc aacatggacg
     1381 gcactgcgct ctacgaggct gtggctgcca tctttattgc ccaggtcaac aactacgagc
     1441 tagactttgg ccagatcatc actatcagca ttacagccac tgcagccagc attggggcgg
     1501 ctggcatccc gcaggcaggg ctcgtcacca tggtcattgt gctcacctct gtgggactgc
     1561 cgaccgatga catcaacctc atcatcgctg tagactgggc actggatcgc ttccgaacca
     1621 tgattaacgt gctgggcgat gcgctggcag cagggatcat ggcccacatc tgccggaagg
     1681 attttgctca ggacatgggc actgagaaat tgctgccctg tgaaaccaag ccagtgacac
     1741 tgcaggagat cgtggctgcc cagcagaacg gctgtgtgaa gagtgtggct gaggcctcag
     1801 agctaaccct gggccccaag tgtccacacc acatcccggt ccaggtagag caggatgaag
     1861 agctggccac tgccagccta gaccactgca ctatcgagat caatgagctg gagaccaatg
     1921 tgtgagcctg cagggccgca gagccaggcc agaccctgag gtttgggcta agcgtaggag
     1981 ttaaactcaa aacatacctg agcatctggt acatcccacc ctgacgggct agccagccac
     2041 cgatgagaaa tagcatctca aaagggagac aactgtgtgc agaggcccca gtcagcaact
     2101 atggctctct cgtggcccag ctgtgacagt ttctagtacc tgagcccatg aaggcacctg
     2161 gtaggggtat ttgcctattc tttgtggaaa aacagctggg ggaggggtgg gtctgagagc
     2221 taaaaccact ccttgaaaga accatcatgg ccaagaggtt aattcaagtc tttggcgtct
     2281 cagccactcc cttctaatga acaaggaaca gtgaaagagg ttctgccttc tccagggtcc
     2341 ccacggccac aacagcttcc aactcaggaa gatataacaa cagtgtccct gtttctgccc
     2401 tagctgcgcc ctggccaggt caaccctgct ccaccccaca gcatgtggct ttaactcaag
     2461 aagggctggc ccaccccagg tctgaggcct gctgccttca cgttacagcc tgtccgtgtc
     2521 tgtcctccag acctctctct catctaacat ggagactgat gccactaggg ctgggagacc
     2581 caatgggtac agctcagcca gcctttcatg agatgggtgg gcaaagaggg ctagaaagag
     2641 aaagacccag cttgggacgc tctggccaag tgactagcag tactttgggg tctgaactct
     2701 ttgggtggca aaatggagtg agagtcccca gtcccttccg tgtttgcaat aacgtgataa
     2761 taaaaatctt tgatttttca agactc
//
