LOCUS       NM_001108613            2276 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 17 member 9 (Slc17a9),
            mRNA.
ACCESSION   NM_001108613 XM_001059811 XM_342601
VERSION     NM_001108613.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2276)
  AUTHORS   Mizuhara,M., Kometani-Gunjigake,K., Nakao-Kuroishi,K., Toyono,T.,
            Hitomi,S., Morii,A., Shiga,M., Seta,Y., Ono,K. and Kawamoto,T.
  TITLE     Vesicular nucleotide transporter mediates adenosine triphosphate
            release in compressed human periodontal ligament fibroblast cells
            and participates in tooth movement-induced nociception in rats
  JOURNAL   Arch Oral Biol 110, 104607 (2020)
   PUBMED   31810015
  REMARK    GeneRIF: results indicate that release of ATP from periodontal
            ligament cells via VNUT is important for nociceptive transduction
            during orthodontic treatment
REFERENCE   2  (bases 1 to 2276)
  AUTHORS   Fois,G., Winkelmann,V.E., Bareis,L., Staudenmaier,L., Hecht,E.,
            Ziller,C., Ehinger,K., Schymeinsky,J., Kranz,C. and Frick,M.
  TITLE     ATP is stored in lamellar bodies to activate vesicular P2X4 in an
            autocrine fashion upon exocytosis
  JOURNAL   J Gen Physiol 150 (2), 277-291 (2018)
   PUBMED   29282210
REFERENCE   3  (bases 1 to 2276)
  AUTHORS   Nishida,K., Nomura,Y., Kawamori,K., Moriyama,Y. and Nagasawa,K.
  TITLE     Expression profile of vesicular nucleotide transporter (VNUT,
            SLC17A9) in subpopulations of rat dorsal root ganglion neurons
  JOURNAL   Neurosci Lett 579, 75-79 (2014)
   PUBMED   25043192
  REMARK    GeneRIF: These results suggest that VNUT plays a role in ATP
            accumulation in dorsal root ganglion neurons
REFERENCE   4  (bases 1 to 2276)
  AUTHORS   Ivatt,R.M., Sanchez-Martinez,A., Godena,V.K., Brown,S., Ziviani,E.
            and Whitworth,A.J.
  TITLE     Genome-wide RNAi screen identifies the Parkinson disease GWAS risk
            locus SREBF1 as a regulator of mitophagy
  JOURNAL   Proc Natl Acad Sci U S A 111 (23), 8494-8499 (2014)
   PUBMED   24912190
REFERENCE   5  (bases 1 to 2276)
  AUTHORS   Harada,Y. and Hiasa,M.
  TITLE     Immunological identification of vesicular nucleotide transporter in
            intestinal L cells
  JOURNAL   Biol Pharm Bull 37 (7), 1090-1095 (2014)
   PUBMED   24989000
  REMARK    GeneRIF: These results demonstrate that intestinal L cells express
            VNUT (vesicular nucleotide transporter )and suggest that L cells
            are purinergic in nature and secrete nucleotides.
REFERENCE   6  (bases 1 to 2276)
  AUTHORS   Larsson,M., Sawada,K., Morland,C., Hiasa,M., Ormel,L., Moriyama,Y.
            and Gundersen,V.
  TITLE     Functional and anatomical identification of a vesicular transporter
            mediating neuronal ATP release
  JOURNAL   Cereb Cortex 22 (5), 1203-1214 (2012)
   PUBMED   21810784
  REMARK    GeneRIF: VNUT mediates transport of ATP into synaptic vesicles of
            hippocampal neurons
REFERENCE   7  (bases 1 to 2276)
  AUTHORS   Sawada,K., Echigo,N., Juge,N., Miyaji,T., Otsuka,M., Omote,H.,
            Yamamoto,A. and Moriyama,Y.
  TITLE     Identification of a vesicular nucleotide transporter
  JOURNAL   Proc Natl Acad Sci U S A 105 (15), 5683-5686 (2008)
   PUBMED   18375752
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474066.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001059811.1, XM_342601.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132266,
                              SAMD00132291 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2276
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..2276
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /note="solute carrier family 17 member 9"
                     /db_xref="GeneID:362287"
                     /db_xref="RGD:1311940"
     exon            1..128
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..1380
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /note="solute carrier family 17 (vesicular nucleotide
                     transporter), member 9; Vesicular nucleotide transporter"
                     /codon_start=1
                     /product="voltage-gated purine nucleotide uniporter
                     SLC17A9"
                     /protein_id="NP_001102083.1"
                     /db_xref="GeneID:362287"
                     /db_xref="RGD:1311940"
                     /translation="MPSQRSSLMQPIPEETRKTPSAAAEDKRWSRPECQLWTGMLLLG
                     TCLLYCTRVTMPVCTVAMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEK
                     VILLSASAWGFITVTTPLLAHLGSGHLAFVTFSRILTGLLQGVYFPALTSLLSQRVQE
                     SERSFTYSTVGAGSQVGTLVTGGIGSVLLDRCGWQSVFYFSGGLTLLWVYYVYKYLLD
                     EKDLVLALGVLAQGLPVTRPSKVPWRQLFRKASVWAVICSQLSSACSFFILLSWLPTF
                     FKETFPHSKGWVFNVVPWLLAIPASLFSGFISDRLISQGYRVITVRKFMQVMGLGLSS
                     IFALCLGHTTSFLKSMIFASASIGFQTFNHSGISVNIQDLAPSCAGFLFGVANTAGAL
                     AGVVGVCLGGYLIETTGSWTCVFHLVAIVSNLGLGTFLVFGKAQRVDLVPTHEDL"
     exon            129..326
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            327..466
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            467..566
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            567..697
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            698..794
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            795..891
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            892..979
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1014
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1130
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1186
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1216
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..2276
                     /gene="Slc17a9"
                     /gene_synonym="RGD1311940; VNUT"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctgaggtg ggagggcacg gtgcacaacg gtgcccatgc catcccagcg ctctagcctg
       61 atgcagccaa tcccagagga gacccgcaag accccttctg cggcagcaga ggacaaacgg
      121 tggtccaggc ctgaatgcca gctatggacg gggatgttgc tcctgggcac ctgcttgctg
      181 tactgcacgc gtgtcaccat gcctgtctgt accgttgcca tgagccagga cttcggctgg
      241 aacaagaagg aggctggtat cgtgctcagc agcttcttct ggggctactg cctgactcag
      301 gtggtgggcg gccaccttgg ggatcgcatt ggaggtgaga aggtcatctt gctgtcagcc
      361 tctgcctggg gcttcatcac tgtcaccaca ccactgcttg cccacctcgg cagcggccac
      421 ctggccttcg tgacattctc tcgaatactc accggtctgc tccaaggtgt ctactttcca
      481 gccctgacca gtctgctgtc ccagagagtg caggagagcg agagatcctt tacttacagc
      541 actgtgggtg ctggctccca ggtcgggact ctggtgactg ggggcatagg gtctgtgctc
      601 ctggaccggt gtggctggca gagtgtcttc tacttctcag gcggcctcac cttgctctgg
      661 gtgtactacg tgtacaagta cctgctggat gagaaagacc ttgtcctggc cctgggtgtc
      721 ctggcacaag gcctacctgt gaccaggccc tccaaagtgc cctggagaca actcttccgg
      781 aaggcctctg tctgggcggt aatctgctca cagctgtcct cagcttgctc tttcttcatt
      841 ctactctcct ggctacccac cttcttcaag gagaccttcc cccactccaa gggctgggtc
      901 ttcaatgtgg taccctggtt gctggcaatt cctgccagtt tgttcagcgg gttcatctct
      961 gaccgcctca tcagtcaggg ttacagagtc atcacggtgc gtaagttcat gcaggtcatg
     1021 ggccttggtc tgtcaagcat ttttgccctg tgtctgggtc acaccacaag cttcctcaag
     1081 tctatgatct ttgcgtcagc gtccattggc ttccagacct tcaaccacag tggtatttca
     1141 gtcaacattc aggacctggc cccatcctgt gctggtttcc tgtttggtgt agccaacact
     1201 gcaggggcct tggcaggtgt ggtaggcgtg tgtctaggtg gctatctgat cgagaccact
     1261 ggctcctgga cctgtgtgtt ccacctggtg gccatcgtca gcaacctggg actgggcacc
     1321 tttctggtgt ttgggaaggc acagagggtg gacctggtac ccactcatga ggacctctag
     1381 cttcctgacg atcagtcccc aggacatgac gtcagcagcc taaagacaac aactctgtcg
     1441 gtgaaactct gggaactcca cctcggatgt atgagcagac aacaagacca cagtctcctg
     1501 gggaatccaa atgagttgga gagatagcct gagtgcacac aggagtaagg tcatgactcc
     1561 acaaatgctt gctagtcctg gcttctctca ggttcagtgg gactgctgct gttaaggaag
     1621 atacattgcc gatgggaggt ctccacagcc tcagtccatg agggttgttt ccccgacaag
     1681 atttctctgt gttaaggatg cgttgtgtgc tggtagatgt tcatggggca gttccaaccc
     1741 ccacctgctc caggcatctt cctatctcca tctctccagt aacgataccc taagaagtct
     1801 gtagacacta gaccatgtct ccataagaca ggcccacagt tcaaaaccac agagaagcca
     1861 tggtttctgc ttctctccca aagtcaggct gccactccag ctgggccagt gtgcggtagg
     1921 ctagaggtcc ttgcctgcct ttgcagaccc tggttcccat cctgtggatc tctcagcact
     1981 actgatgtgt cctgggctgg caggtgcctg gaagtcctca ggctttgcct ggacactcca
     2041 gacagcacag accccagaac aaggaggaac acccccacca cacacacaca cacacacaca
     2101 cacacacaca cacccatctg gccttgtttt tctacctccc ctcttattct ttgtagagct
     2161 ggtcatttca tgagctgatc atgaattctc caagatgcat attagattat ctttatagat
     2221 atggtgagtc tcgccagggc cttatttaag tgaaaaccat taaactattt aaatat
//
