LOCUS       NM_153622               2292 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus solute carrier family 17 member 3 (Slc17a3),
            mRNA.
ACCESSION   NM_153622
VERSION     NM_153622.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2292)
  AUTHORS   Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K,
            Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K,
            Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida
            S, Wempe MF, Endou H and Sakurai H.
  TITLE     Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common
            renal secretory pathway for drugs and urate
  JOURNAL   J Biol Chem 285 (45), 35123-35132 (2010)
   PUBMED   20810651
REFERENCE   2  (bases 1 to 2292)
  AUTHORS   Brandstatter A, Lamina C, Kiechl S, Hunt SC, Coassin S, Paulweber
            B, Kramer F, Summerer M, Willeit J, Kedenko L, Adams TD and
            Kronenberg F.
  TITLE     Sex and age interaction with genetic association of atherogenic
            uric acid concentrations
  JOURNAL   Atherosclerosis 210 (2), 474-478 (2010)
   PUBMED   20053405
REFERENCE   3  (bases 1 to 2292)
  AUTHORS   Polasek O, Jeroncic I, Mulic R, Klismanic Z, Pehlic M, Zemunik T
            and Kolcic I.
  TITLE     Common variants in SLC17A3 gene affect intra-personal variation in
            serum uric acid levels in longitudinal time series
  JOURNAL   Croat Med J 51 (1), 32-39 (2010)
   PUBMED   20162743
REFERENCE   4  (bases 1 to 2292)
  AUTHORS   Dehghan A, Kottgen A, Yang Q, Hwang SJ, Kao WL, Rivadeneira F,
            Boerwinkle E, Levy D, Hofman A, Astor BC, Benjamin EJ, van Duijn
            CM, Witteman JC, Coresh J and Fox CS.
  TITLE     Association of three genetic loci with uric acid concentration and
            risk of gout: a genome-wide association study
  JOURNAL   Lancet 372 (9654), 1953-1961 (2008)
   PUBMED   18834626
REFERENCE   5  (bases 1 to 2292)
  AUTHORS   Melis D, Havelaar AC, Verbeek E, Smit GP, Benedetti A, Mancini GM
            and Verheijen F.
  TITLE     NPT4, a new microsomal phosphate transporter: mutation analysis in
            glycogen storage disease type Ic
  JOURNAL   J Inherit Metab Dis 27 (6), 725-733 (2004)
   PUBMED   15505377
REFERENCE   6  (bases 1 to 2292)
  AUTHORS   Puschett JB, Whitbred J, Ianosi-Irimie M, Vu HV, Rabon E, Robinson
            J and Deininger P.
  TITLE     Molecular effects of volume expansion on the renal sodium phosphate
            cotransporter
  JOURNAL   Am J Med Sci 326 (1), 1-8 (2003)
   PUBMED   12861119
  REMARK    GeneRIF: effects of volume expansion on the renal sodium phosphate
            cotransporter
REFERENCE   7  (bases 1 to 2292)
  AUTHORS   Ishibashi K, Matsuzaki T, Takata K and Imai M.
  TITLE     Identification of a new member of type I Na/phosphate
            co-transporter in the rat kidney
  JOURNAL   Nephron Physiol 94 (1), p10-p18 (2003)
   PUBMED   12806205
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB025223.1.
            
            On May 23, 2007 this sequence version replaced NM_153622.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB025223.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2292              AB025223.1         25-2316
FEATURES             Location/Qualifiers
     source          1..2292
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p11"
     gene            1..2292
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /note="solute carrier family 17 member 3"
                     /db_xref="GeneID:266730"
                     /db_xref="RGD:628815"
     exon            1..52
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            53..169
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..1575
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /note="solute carrier family 17 (organic anion
                     transporter), member 3; Na/Pi cotransporter 4;
                     sodium-phosphate cotransporter; solute carrier family 17
                     (sodium phosphate), member 3"
                     /codon_start=1
                     /product="sodium-dependent phosphate transport protein 4"
                     /protein_id="NP_705886.1"
                     /db_xref="GeneID:266730"
                     /db_xref="RGD:628815"
                     /translation="MATMVELSPTSEQCEFVLGLPVNKKTPPRKVPSLCSMRYSIAFI
                     AHICNFTLIAQNSIISITMVAMVNNTDQPSHLNSSTEWFPDGLNGDQHEASKHLSIKA
                     PVYNWSPQTQGIIFSSVQYGMMLMQGPGGYLAGKLGTKKVVGIALLGSSLLTLCIPLA
                     ANLGLAFLLATRAVQGLTQGAGYGGQFALWQKWAPPNERSRLCSIAMSGMILGIFAVL
                     LVGGIISEALGWPFVFYIFGSIGVVCCLLWLILVYDDPVSHPWISSPEKEYILSSLDQ
                     QFNSEEQPLPIKAMLKSLPLWSMCLCSMTHQWLVNTLIIYTPTYISSVFKVNIRDNGL
                     LSSLPFFVAWVIGILGGLLADFLLSKNFRLITVRKIITILGNTPPAALVVALPYVQSS
                     YIATTTFLTLSCGLSPLCQSGVYINALDIAPRYASLLMGTSRGLAHSSAVMVPIVAGF
                     FLNQDSEFGWRNFFFVLFAINLFGLIIYLVFAKADIQEWARERKLTRL"
     exon            170..381
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            382..615
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            616..703
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            704..790
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            791..909
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1071
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1201
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1349
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1440
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1577
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..2279
                     /gene="Slc17a3"
                     /gene_synonym="Rnpt4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagaagcct gctgaggaaa cactggaaag ccttacctca ggcactaagt tgctaattat
       61 ccagaaggaa aaacgacaat ggccacaatg gtagaactga gccctacaag tgagcagtgt
      121 gagtttgtcc taggtctgcc agtgaataag aagacccctc cccggaaagt cccgagttta
      181 tgttccatgc gctattcaat agccttcatc gcacatatct gcaacttcac attgatagca
      241 cagaattcca tcataagcat caccatggta gccatggtca acaacacgga ccagccatcc
      301 cacctcaata gctctactga atggtttcct gatggtttaa acggtgatca acatgaagct
      361 tcaaagcatc tttctataaa ggcccctgtg tataactgga gtcctcaaac ccaaggaatc
      421 atcttcagct ctgtccagta tggcatgatg ctgatgcagg gtcctggcgg atacttggca
      481 gggaaattag gaacaaagaa agtggttgga attgctctgt tgggatcgtc actgctcact
      541 ctctgcatcc cactggctgc caatcttgga ctagcttttc tcctggcaac tcgagcagtt
      601 cagggcttaa cccagggcgc tggatatggg ggacagtttg cactctggca gaagtgggct
      661 cctccaaatg aacgcagccg actctgcagc attgccatgt caggaatgat attgggaatc
      721 tttgctgtgc tccttgtggg cggcatcatt agtgaagccc tcgggtggcc ctttgtcttt
      781 tatatctttg gaagtattgg tgtggtctgc tgccttctct ggctcattct ggtttatgat
      841 gaccctgtct ctcacccatg gataagtagc ccagaaaagg agtatatttt atcctccctg
      901 gaccaacagt tcaactcaga agagcaacca cttcccatca aagctatgct caaatctctg
      961 cctctctggt ccatgtgtct ttgcagtatg acccatcagt ggcttgttaa cacccttata
     1021 atatatactc caacctacat cagttctgtg ttcaaagtta acatcagaga taatgggctc
     1081 ctgtcttctc ttcccttttt tgttgcctgg gtcattggta tcctgggagg cctgctggca
     1141 gatttcctac taagcaagaa ttttaggctc ataactgtga gaaaaatcat cacaatctta
     1201 ggaaatactc cccctgctgc ccttgttgtg gctctgccct atgtccaatc cagctatatt
     1261 gcaacaacta catttctgac cctttcctgt ggactaagcc ctctatgtca gtcaggagtc
     1321 tatattaatg cattagatat tgctccaagg tatgccagcc ttctcatggg aacatcaaga
     1381 gggctcgcac attcatctgc tgtaatggta cccattgttg ctggcttttt cctcaatcag
     1441 gactctgaat tcgggtggag gaatttcttt tttgttctat ttgcgattaa cctatttggc
     1501 ttaatcatct acctcgtgtt tgcgaaagca gatatccaag aatgggctag agagaggaag
     1561 ctcacccgtt tgtgaaggtg ctttaatcct ggacttcagt gcaactacag aagagaatga
     1621 ctgtcataca gctgtgataa aacatcatgg ccaaagcatt gtgggacaaa aagaatttat
     1681 ttcaccctac aactctcagg ccacagttca tcaccaagag aagacagtgc aggaactcca
     1741 ggcagaaact gaagcagagg ccatggggag tgctgcttac aggcttgttc tccatgggtt
     1801 gctcatgctg ctttcttata caactcagca ccacctacct gcccaaggtt ggcaccaccc
     1861 caagtgatcc aggtcttcca acatccatca ttaaccaaga aaatactata taagacttgt
     1921 ctataggcaa tctgatggaa gcttttctca tctggagtcc ttctttccag acacctctag
     1981 cctgtgtcac cttgacacaa taaatcaacc aggacaatga ccaaggagaa aactgattgt
     2041 tcctgagtaa taaaaataat taacatcact aaacagtcca aaaatggctt agtagcatgg
     2101 caaaggccaa gctatgagca acaagggtgg ggttcagtcc tgagcagtct aacccaagag
     2161 actgcttgaa gcttctacca cacaccatcc atgaaggtgt gttctacttg gatcagaaac
     2221 acttgccaaa agtcaacaaa ctgtacctgt tcttttatta aatctttatg acaaccccaa
     2281 aaaaaaaaaa aa
//
