LOCUS       NM_031744               1829 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 16 member 8 (Slc16a8),
            mRNA.
ACCESSION   NM_031744
VERSION     NM_031744.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1829)
  AUTHORS   Wilson,M.C., Meredith,D., Fox,J.E., Manoharan,C., Davies,A.J. and
            Halestrap,A.P.
  TITLE     Basigin (CD147) is the target for organomercurial inhibition of
            monocarboxylate transporter isoforms 1 and 4: the ancillary protein
            for the insensitive MCT2 is EMBIGIN (gp70)
  JOURNAL   J Biol Chem 280 (29), 27213-27221 (2005)
   PUBMED   15917240
REFERENCE   2  (bases 1 to 1829)
  AUTHORS   Philp,N.J., Yoon,H. and Grollman,E.F.
  TITLE     Monocarboxylate transporter MCT1 is located in the apical membrane
            and MCT3 in the basal membrane of rat RPE
  JOURNAL   Am J Physiol 274 (6), R1824-R1828 (1998)
   PUBMED   9841555
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On May 9, 2012 this sequence version replaced NM_031744.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760433, SAMN06621351
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-118               JAXUCZ010000007.1  112702379-112702496 c
            119-197             JAXUCZ010000007.1  112701714-112701792 c
            198-425             JAXUCZ010000007.1  112701346-112701573 c
            426-569             JAXUCZ010000007.1  112700594-112700737 c
            570-1337            JAXUCZ010000007.1  112699612-112700379 c
            1338-1829           JAXUCZ010000007.1  112698701-112699192 c
FEATURES             Location/Qualifiers
     source          1..1829
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1829
                     /gene="Slc16a8"
                     /gene_synonym="Mct3"
                     /note="solute carrier family 16 member 8"
                     /db_xref="GeneID:65200"
                     /db_xref="RGD:69282"
     exon            1..118
                     /gene="Slc16a8"
                     /gene_synonym="Mct3"
                     /inference="alignment:Splign:2.1.0"
     exon            119..197
                     /gene="Slc16a8"
                     /gene_synonym="Mct3"
                     /inference="alignment:Splign:2.1.0"
     exon            198..425
                     /gene="Slc16a8"
                     /gene_synonym="Mct3"
                     /inference="alignment:Splign:2.1.0"
     CDS             212..1684
                     /gene="Slc16a8"
                     /gene_synonym="Mct3"
                     /note="solute carrier family 16 (monocarboxylic acid
                     transporters), member 8; solute carrier family 16, member
                     8 (monocarboxylic acid transporter 3); solute carrier
                     family 16 (monocarboxylate transporter), member 8"
                     /codon_start=1
                     /product="monocarboxylate transporter 3"
                     /protein_id="NP_113932.2"
                     /db_xref="GeneID:65200"
                     /db_xref="RGD:69282"
                     /translation="MGAGGPRRGAGPPDGGWGWVVLGACFVITGFAYGFPKAVSVFFR
                     ELKRDFGAGYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILA
                     SFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTL
                     SPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPQPRPDPAPPGGRARHRQL
                     LDLAVCTDRTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDI
                     VARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYG
                     MVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLA
                     GSEVVLAGVFMAVTTYCCQRCSKDIPPGPSAEGGTSDTEDVEAERDSEPMPASTEEPG
                     SLEALEVLSPRAGSPEPEEEAVPDLSHESVGGHEAHGQNA"
     exon            426..569
                     /gene="Slc16a8"
                     /gene_synonym="Mct3"
                     /inference="alignment:Splign:2.1.0"
     exon            570..1337
                     /gene="Slc16a8"
                     /gene_synonym="Mct3"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1829
                     /gene="Slc16a8"
                     /gene_synonym="Mct3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcaacaggag tgcagccacc agagtcaagg ctgttggaca ctctcagagc tagaggctgc
       61 ccctcccgaa ggcctcagga gatgtgaggt tcaaccctaa atccagagtc aggtccaggt
      121 ccccagagga gaggagccct ggtgaggaaa cctcaaagtc aagtctccat tcagccttca
      181 caggcctttg caggaagcag aagcagaggc aatgggtgct ggcggcccgc ggcggggtgc
      241 tggtcctcca gatggtggct ggggctgggt ggtactgggc gcctgcttcg tgatcactgg
      301 cttcgcctat ggcttcccta aggctgtgag cgtcttcttc cgagagctca agcgcgactt
      361 cggggcaggt tacagtgaca cagcctgggt gtcttccatc atgctggcta tgctctacgg
      421 cacgggcccc ttgtccagca tcctcgtgac gcgctttggc tgtcgcccag tgatgctggc
      481 tggtggactg ctggcttcag cgggcatgat tctggcttcc tttgcctcgc gcctcctgga
      541 gctgtacctg acggctgggg tactcacagg cctgggcctg gctctcaact tccagccgtc
      601 gctcatcatg ctggggctct acttcgagcg gcgacggccc ctggccaacg ggctggcagc
      661 agcaggcagc ccggtgtttc tgtccacgct gtcgcctctc ggccagctgc tgggggagcg
      721 ctttggctgg cgcggcggct tcctgctgtt tggcggtctc ctgctgcact gttgcgcctg
      781 tggggctgtc atgcgtccgc cccctggacc ccagccgcgc ccagaccctg cgccccccgg
      841 tggccgggct cgccacaggc agctgctgga cttggcagtg tgcactgacc gcactttcat
      901 ggtatacatg gttaccaagt tcctgatggc gctcgggctc tttgtgccgg ctatcctgct
      961 ggtgaactac gccaaggacg cgggtgtgcc tgatgccgag gccgccttct tgttgtctat
     1021 cgtgggcttt gtggacatcg tggcacggcc agcgtgtggt gctttggcgg gtctggggcg
     1081 actgagaccc cacgtcccct atctcttcag cctggccttg ttggccaatg ggctcacgga
     1141 cctgattagc gctcgtgcgc gctcctacgg cacccttgtg gctttctgca tcgccttcgg
     1201 cctctcctat ggcatggtgg gcgcgctgca atttgaggtg ctcatggcga ccgtgggtgc
     1261 gccccgcttc cctagtgcct tgggcctagt gctgctcgtg gaggccgtgg ctgtgctcat
     1321 aggaccgcct tctgccggcc gcctggtgga tgctctgaag aactatgaga tcatcttcta
     1381 ccttgctggt tctgaggtgg tcttggcagg agtcttcatg gcagttacca catactgctg
     1441 ccagcgctgc tctaaggaca tcccaccagg tccatctgct gagggaggaa ccagcgacac
     1501 agaggacgtg gaggctgaga gggactctga gccaatgcct gccagcactg aagagcctgg
     1561 cagcctggaa gctctggagg tgctgagccc cagggctggg tccccagaac cagaggagga
     1621 ggcagtgcct gacctgagtc acgagtctgt aggtggccat gaggcacatg gccaaaacgc
     1681 ttgaaaatgt ggcttcctct ctgagggcct ggtacgtggg gaaccagcct ggggtggtcc
     1741 cttgggcacc caatctgtta ggccctgttc acagtgaagc tgctgggggc tgccaggagc
     1801 acacgttgat aaaagccccc taaaagata
//
