LOCUS       NM_139341               1979 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 15 member 3 (Slc15a3),
            mRNA.
ACCESSION   NM_139341
VERSION     NM_139341.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Romano,A., Barca,A., Kottra,G., Daniel,H., Storelli,C. and Verri,T.
  TITLE     Functional expression of SLC15 peptide transporters in rat thyroid
            follicular cells
  JOURNAL   Mol Cell Endocrinol 315 (1-2), 174-181 (2010)
   PUBMED   19913073
  REMARK    GeneRIF: These findings represent the first evidence that peptide
            transport via SLC15a1, 2, 3, and 4 occurs in thyroid follicular
            cells.
REFERENCE   2  (bases 1 to 1979)
  AUTHORS   Schroder,B., Wrocklage,C., Pan,C., Jager,R., Kosters,B.,
            Schafer,H., Elsasser,H.P., Mann,M. and Hasilik,A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
REFERENCE   3  (bases 1 to 1979)
  AUTHORS   Sakata,K., Yamashita,T., Maeda,M., Moriyama,Y., Shimada,S. and
            Tohyama,M.
  TITLE     Cloning of a lymphatic peptide/histidine transporter
  JOURNAL   Biochem J 356 (Pt 1), 53-60 (2001)
   PUBMED   11336635
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB026665.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB026665.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1979
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /note="solute carrier family 15 member 3"
                     /db_xref="GeneID:246239"
                     /db_xref="RGD:628663"
     exon            1..635
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1826
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /note="peptide transporter 3; peptide/histidine
                     transporter 2; peptide/histidine transporter PHT2; solute
                     carrier family 15 (oligopeptide transporter), member 3"
                     /codon_start=1
                     /product="solute carrier family 15 member 3"
                     /protein_id="NP_647557.1"
                     /db_xref="GeneID:246239"
                     /db_xref="RGD:628663"
                     /translation="MSALRAEQQPSRSGERQPLVAQGRWGPRRWRRTAAAAVLLVEML
                     ERAAFFGVTSNLVLYLNSLNFNWDGEHASRATLLFLGASYLLAPVGGWLADVYLGRFL
                     AISLSLLLYLAATGLLLTTITDDGRRSFCGEMPELPLKPACPSANCQGSWSSPYCATT
                     LYLVLLLLALAASSVRSNLTSFGADQVMDLGRDATRRFFNWFYWSINLGAILSLLVVA
                     FIEQNISFLQGYSIIVGLVGLAFFIFLIATPVFITKPPTGSQVSSMLNLAFQNCCPGW
                     QWWRRPSSRNSEGAHLLPDQRSNQPGPSPQEDMANFQVLLKVLPVMVTLVPYWMVYFQ
                     MQSTYVLQGLHLHIPNIFRTNPNISLPLRSDSSNYRIPEAWLLLANVAVILILVPVKD
                     HLIDPLLLRCKLLPSALQKMALGMFFGFTSIIVAGVLEKERLQYIAANQTVPQLIGKD
                     LYYAAPLSIWWQIPQYLLIGISEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLSGVGS
                     LLGSGLVALLSLPGGWMYCPKDFGNINNCRMDLYFFLLAGIQAVTAVLFLWIAGRYER
                     TRQDPDSQNSTSRVRG"
     exon            636..931
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1079
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1187
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1356
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1515
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /inference="alignment:Splign:2.1.0"
     exon            1516..1671
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1959
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1958
                     /gene="Slc15a3"
                     /gene_synonym="Pht2"
ORIGIN      
        1 aagagggcaa tcggggttaa gagagaagag gggaggacaa aggaaagagt ctgggtcacg
       61 gagacaggaa gcccacgatg tccgcacttc gcgccgaaca gcagccaagc agatccggag
      121 agaggcaacc actggtggct caaggccggt gggggccccg acggtggagg cggacagcag
      181 ctgctgcggt gctgctagtg gagatgctgg aacgcgctgc cttctttggc gtcacctcca
      241 acctcgtgct ctacctcaac agcttgaact tcaactggga tggtgagcac gcgtcgcggg
      301 ccacactcct cttcttaggc gcctcctacc tgctggctcc ggtgggaggc tggctggccg
      361 acgtgtacct gggccgtttc cttgctattt cgctcagcct gctgctctac ctggctgcca
      421 ctggcttgtt gctcaccacc atcaccgacg atggccgcag atccttctgt ggagagatgc
      481 ccgagttgcc actgaaacct gcctgtccat ccgcaaactg ccaaggctcc tggtccagcc
      541 cctactgcgc gaccaccctc tacttagtgt tgcttctctt ggcgctggct gccagctccg
      601 tcaggagcaa cctcacctcg ttcggggccg accaggtgat ggatctcggc cgtgatgcca
      661 cccgccgctt cttcaactgg ttctattgga gcatcaatct gggtgccatt ctgtccctgc
      721 tggtggtggc cttcatcgaa cagaacatca gcttcctaca gggctacagc atcatcgtgg
      781 gcctcgtggg cctggcattc ttcatttttc tcatcgccac acccgtcttc atcaccaagc
      841 ccccaacagg cagccaagtg tcatctatgc tgaaccttgc attccaaaac tgctgtcccg
      901 ggtggcagtg gtggcggagg ccctcttcca ggaactctga aggtgctcac ctgttgcctg
      961 accagaggtc taaccagcct ggaccttctc cacaagaaga tatggccaac ttccaggtgc
     1021 tgttgaaggt cctgcctgtg atggtgaccc ttgtgcctta ctggatggtg tatttccaga
     1081 tgcagtccac ctatgtccta caaggtctcc acctccatat ccccaacatc ttccgcacca
     1141 accctaacat ctctttgcca ctgagatcgg atagcagtaa ctacaggatc ccagaagcct
     1201 ggctcctgct ggccaatgtt gcagtgatac tgattctggt ccctgtcaag gaccacttaa
     1261 ttgatcctct gctgctgcgg tgtaagctgc tgccctcggc tctgcagaag atggcgctgg
     1321 gcatgttctt tgggttcact tccatcatcg tggcaggagt cctggaaaaa gagcgcttgc
     1381 agtacattgc tgccaaccag acagtgcctc agctgattgg gaaggactta tactatgcgg
     1441 caccactgtc catctggtgg caaatccccc aatacctgct catcgggatc agtgagattt
     1501 ttgccagcat cccaggtctg gagttcgctt actcggaagc cccacgctcc atgcagggcg
     1561 caatcatggg catcttcttc tgcctttcgg gggtaggttc actgctaggc tctggcttgg
     1621 tggccctact gtcccttcct ggaggctgga tgtactgccc taaggacttc gggaacatca
     1681 acaactgtcg tatggacctt tacttcttcc tgctagccgg cattcaggct gtcacagctg
     1741 tcctgtttct ctggattgct ggtcgttatg agaggactcg tcaggaccca gactcccaga
     1801 actcaaccag cagagtcagg ggctgaaatg gtctccaccc accctgatag agagtgtcac
     1861 agcagtacca gccatgccca ttcttttatc atttattctg tacccaacat tagaatgaag
     1921 tggttcccat aaataagggg catgcgccct ccctcttgaa aaaaaaaaaa aaaaaaaaa
//
