LOCUS       NM_031651               2924 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus solute carrier family 13 member 1 (Slc13a1),
            mRNA.
ACCESSION   NM_031651
VERSION     NM_031651.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2924)
  AUTHORS   Regeer,R.R., Nicke,A. and Markovich,D.
  TITLE     Quaternary structure and apical membrane sorting of the mammalian
            NaSi-1 sulfate transporter in renal cell lines
  JOURNAL   Int J Biochem Cell Biol 39 (12), 2240-2251 (2007)
   PUBMED   17681482
  REMARK    GeneRIF: Data demonstrate that NaSi-1 forms a dimeric protein which
            is glycosylated at N591, whose sorting to the apical membrane in
            renal epithelial cells is brefeldin A-sensitive and independent of
            lipid rafts or glycosylation.
REFERENCE   2  (bases 1 to 2924)
  AUTHORS   Beck,L. and Markovich,D.
  TITLE     The mouse Na(+)-sulfate cotransporter gene Nas1. Cloning, tissue
            distribution, gene structure, chromosomal assignment, and
            transcriptional regulation by vitamin D
  JOURNAL   J Biol Chem 275 (16), 11880-11890 (2000)
   PUBMED   10766815
REFERENCE   3  (bases 1 to 2924)
  AUTHORS   Lotscher,M., Custer,M., Quabius,E.S., Kaissling,B., Murer,H. and
            Biber,J.
  TITLE     Immunolocalization of Na/SO4-cotransport (NaSi-1) in rat kidney
  JOURNAL   Pflugers Arch 432 (3), 373-378 (1996)
   PUBMED   8765995
REFERENCE   4  (bases 1 to 2924)
  AUTHORS   Norbis,F., Perego,C., Markovich,D., Stange,G., Verri,T. and
            Murer,H.
  TITLE     cDNA cloning of a rat small-intestinal Na+/SO4(2-) cotransporter
  JOURNAL   Pflugers Arch 428 (3-4), 217-223 (1994)
   PUBMED   7816544
REFERENCE   5  (bases 1 to 2924)
  AUTHORS   Busch,A.E., Waldegger,S., Herzer,T., Biber,J., Markovich,D.,
            Murer,H. and Lang,F.
  TITLE     Electrogenic cotransport of Na+ and sulfate in Xenopus oocytes
            expressing the cloned Na+SO4(2-) transport protein NaSi-1
  JOURNAL   J Biol Chem 269 (17), 12407-12409 (1994)
   PUBMED   8175644
REFERENCE   6  (bases 1 to 2924)
  AUTHORS   Markovich,D., Forgo,J., Stange,G., Biber,J. and Murer,H.
  TITLE     Expression cloning of rat renal Na+/SO4(2-) cotransport
  JOURNAL   Proc Natl Acad Sci U S A 90 (17), 8073-8077 (1993)
   PUBMED   7690140
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 30, 2020 this sequence version replaced NM_031651.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U08031.1, SRR26643288.18045.1
                                           [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-127               JAXUCZ010000004.1  53612578-53612704   c
            128-256             JAXUCZ010000004.1  53598699-53598827   c
            257-393             JAXUCZ010000004.1  53583840-53583976   c
            394-581             JAXUCZ010000004.1  53581496-53581683   c
            582-639             JAXUCZ010000004.1  53580811-53580868   c
            640-688             JAXUCZ010000004.1  53580682-53580730   c
            689-840             JAXUCZ010000004.1  53565443-53565594   c
            841-960             JAXUCZ010000004.1  53556112-53556231   c
            961-1059            JAXUCZ010000004.1  53551742-53551840   c
            1060-1161           JAXUCZ010000004.1  53551152-53551253   c
            1162-1268           JAXUCZ010000004.1  53547997-53548103   c
            1269-1378           JAXUCZ010000004.1  53545341-53545450   c
            1379-1540           JAXUCZ010000004.1  53539309-53539470   c
            1541-1678           JAXUCZ010000004.1  53537777-53537914   c
            1679-2924           JAXUCZ010000004.1  53534763-53536008   c
FEATURES             Location/Qualifiers
     source          1..2924
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q22"
     gene            1..2924
                     /gene="Slc13a1"
                     /note="solute carrier family 13 member 1"
                     /db_xref="GeneID:58980"
                     /db_xref="RGD:61919"
     exon            1..127
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1816
                     /gene="Slc13a1"
                     /note="solute carrier family 13 (sodium/sulphate
                     symporters), member 1; solute carrier family 13
                     (sodium/sulfate symporter), member 1; naSi-1; renal
                     sodium/sulfate cotransporter; Na(+)/sulfate cotransporter;
                     solute carrier family 13 (sodium/sulfate symporters),
                     member 1"
                     /codon_start=1
                     /product="solute carrier family 13 member 1"
                     /protein_id="NP_113839.1"
                     /db_xref="GeneID:58980"
                     /db_xref="RGD:61919"
                     /translation="MKLLNYAFVYRRFLLVVFTVLVLLPLPLIIRSKEAECAYILFVI
                     ATFWITEALPLSITALLPGLMFPMFGIMSSTHVASAYFKDFHLLLIGVICLATSIEKW
                     NLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQITS
                     AEAEAEATQMTYFNESAAQGLEVDETIIGQETNERKEKTKPALGSSNDKGKVSSKMET
                     EKNTVTGAKYRSKKDHMMCKLMCLCIAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDC
                     RCLNFGSWFLFSFPVAVILLLLSWIWLQWLFLGFNFKEMFKCGKTKTLKEKACAEVIK
                     QEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVA
                     GILFFLIPAKKLTKMTSTGDIIAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCQ
                     VSGLSSWIGSKLSPLGSLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAI
                     HVNPLHILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVM
                     LGMFTWIEPMFNLHEYPSWAPDIVNQTMP"
     exon            128..256
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            257..393
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            394..581
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            582..639
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            640..688
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            689..840
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            841..960
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1059
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1161
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1268
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1378
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1540
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1678
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..2924
                     /gene="Slc13a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acactgttga aggcacctgc tcaggacaat gaagctcctc aattacgctt ttgtgtatcg
       61 tcgctttctc cttgtggttt tcactgtttt ggttttattg ccactccctc tcatcatccg
      121 tagcaaggaa gcagaatgtg cctacatcct ctttgttatt gccacatttt ggatcacaga
      181 agccttgccc ctgtcaatca cagctctact gcctgggtta atgttcccca tgtttggaat
      241 catgtcttct acacatgtag cttctgctta cttcaaagac tttcaccttc tgctaattgg
      301 agtcatctgc ttagcaacat caatagaaaa atggaatttg cacaagagga ttgctctgag
      361 gatggtgatg atggtggggg tgaatccggc ctggctgacg ttggggttca tgagcagtac
      421 tgccttctta tctatgtggc ttagcaacac ctctactgct gccatggtga tgcccatcgt
      481 ggaggcagtg gcgcagcaga tcaccagtgc tgaagcagag gccgaggcca ctcagatgac
      541 ttatttcaat gaatctgccg cccagggact cgaagttgat gaaactatta ttggacaaga
      601 aacaaatgag aggaaagaga aaacaaaacc agctctagga agcagtaatg acaaagggaa
      661 agtgtcaagc aagatggaga cagaaaagaa cacagtcaca ggagcaaagt atcggtcaaa
      721 gaaggaccac atgatgtgta agctcatgtg tttatgtatt gcttactctt caaccattgg
      781 tggactgacg acaatcactg gtacctccac caacctgatc ttctccgagc atttcaacac
      841 acgctaccct gattgtcgct gcctcaactt tggatcttgg tttttgtttt ccttcccggt
      901 cgctgttatt cttctacttt tgtcttggat ttggcttcaa tggcttttct taggattcaa
      961 ctttaaggag atgttcaagt gtggcaaaac caaaacactc aaagaaaaag cttgtgccga
     1021 ggtgatcaag caagaatatg aaaaacttgg gccaatgagg tatcaagaaa tcgtgacctt
     1081 ggtgatcttc attgtaatgg ccttgctctg gttcagtcgg gaccctggct ttgtcactgg
     1141 ttggtcggtc ctgttttcag agtacccggg ttatgttaca gattcaactg ttgccttagt
     1201 tgcaggaatc cttttctttc taattccagc caagaaactg acaaaaatga catccacagg
     1261 agatattatt gcttttgatt attctcccct gattacttgg aaagaattcc agtcattcat
     1321 gccctgggac atagccattc tcgttggtgg aggctttgcc ctggcagatg gttgtcaggt
     1381 atcaggacta tctagctgga taggaagtaa attatctcct ttaggttcgt taccagtttg
     1441 gctaataatt ctgatatcct ctttgattgt cacatctttg acagaggtag ccagcaaccc
     1501 agctaccatt accattctgt tccccatatt atctcctttg gctgaagcca ttcatgtgaa
     1561 ccctcttcac attttgctgc catccacact ttgtacctca tttgcatttc tcctgccagt
     1621 tgcaaatcca cccaatgcca ttgtgttttc atatggccac ctgaaagtca ttgacatggt
     1681 taaagctgga ctcggagtaa acattttggg tgttgctgtg gtgatgctgg gcatgttcac
     1741 ctggatcgaa cctatgttta acctccacga atatccctcc tgggctcctg acattgttaa
     1801 tcagaccatg ccatgacaca cacacaagag ctaccagttt gcggtggctt caggactcgc
     1861 taagaatgac tgtacggtac agccggattg gactggcaca cgcgaatctt cgatgcagct
     1921 attccaattg cagagcgtgc cccacacatg cccctgtcaa cctcataaga cagagttcat
     1981 atcttttgaa atacaatcaa cgtgcatcta cccgccttcg tccagaaatc aaggttgaga
     2041 cggcatcggc agaccagcta catgctcttt gtccattata atgacactta aggaccttca
     2101 aaaaagttag gccatccgtc cgtcgcatct taaattcgga gttcattggg acatttcaaa
     2161 catcaattca ctatttgaaa tttttcttat gaaactaaag gcagaaaata aagtgtgaaa
     2221 gtaaacgaga cacatggata aatcatttcc acagtgttta tctagggaat tcgctaaacc
     2281 atcaagctaa ggttacttgg tgtaatgtat agagaagtgt gtatttattt attgaaaagt
     2341 ctaactgcac tgttactaaa gtacagacag gacaagttta aattacaata gttacaagtt
     2401 ccaaaattta tgaatctgtt tgatagtaag aaatttataa tgattaattt ctacttgttc
     2461 aaataaacag gctagtattt atgcttctat gggttctgta ccgagcaatg cattttgagt
     2521 agctatgaat aaataaatta tgatttgcag tattttttac agtacagtta gaaaagctat
     2581 gcattaaagc tattaacaca tggtcgtaat gtataacttt tgcatctgtc agaactgaat
     2641 cacaatcctt caggagggaa tctttccttt actctaaaat aggaaaaaaa taaataaacc
     2701 ctctgggttt acaaatttgg aagagcatat ccagaagtgt gttaattgct atctagtact
     2761 atgggaatgg gaacctgtaa caattctgtt gtagacaccg acgcttgggt tcgcagatgt
     2821 ccaggaagtg gctatggcag gataaaatca taaaacactc aaaagctctt ctttatatca
     2881 ttcctgtcac tttattctaa ttaaattcat ttttatttta aaaa
//
