LOCUS       NM_001109630            6107 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus solute carrier family 12, member 6 (Slc12a6),
            mRNA.
ACCESSION   NM_001109630 XM_001066528 XM_001066596 XM_001066648 XM_001066706
            XM_001066756
VERSION     NM_001109630.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6107)
  AUTHORS   Zhang J, Gao G, Begum G, Wang J, Khanna AR, Shmukler BE, Daubner
            GM, de Los Heros P, Davies P, Varghese J, Bhuiyan MI, Duan J, Zhang
            J, Duran D, Alper SL, Sun D, Elledge SJ, Alessi DR and Kahle KT.
  TITLE     Functional kinomics establishes a critical node of volume-sensitive
            cation-Cl- cotransporter regulation in the mammalian brain
  JOURNAL   Sci Rep 6, 35986 (2016)
   PUBMED   27782176
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6107)
  AUTHORS   de Los Heros P, Alessi DR, Gourlay R, Campbell DG, Deak M,
            Macartney TJ, Kahle KT and Zhang J.
  TITLE     The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and
            inhibit the K+-Cl- co-transporters
  JOURNAL   Biochem J 458 (3), 559-573 (2014)
   PUBMED   24393035
REFERENCE   3  (bases 1 to 6107)
  AUTHORS   Melo Z, Cruz-Rangel S, Bautista R, Vazquez N, Castaneda-Bueno M,
            Mount DB, Pasantes-Morales H, Mercado A and Gamba G.
  TITLE     Molecular evidence for a role for K(+)-Cl(-) cotransporters in the
            kidney
  JOURNAL   Am J Physiol Renal Physiol 305 (10), F1402-F1411 (2013)
   PUBMED   24089410
  REMARK    GeneRIF: Data are consistent with a role for KCC3 in the proximal
            tubule glucose reabsorption mechanism.
REFERENCE   4  (bases 1 to 6107)
  AUTHORS   Fujita K, Fujii T, Shimizu T, Takeguchi N and Sakai H.
  TITLE     Role of cholesterol in functional association between K(+)-Cl(-)
            cotransporter-3a and Na+,K(+)-ATPase
  JOURNAL   Biochem Biophys Res Commun 424 (1), 136-140 (2012)
   PUBMED   22732406
  REMARK    GeneRIF: these results suggest that cholesterol is essential for
            eliciting up-regulation of Na(+),K(+)-ATPase activity by KCC3a in
            the KCC3a-alpha1NaK complex.
REFERENCE   5  (bases 1 to 6107)
  AUTHORS   Gagnon KB.
  TITLE     High-grade glioma motility reduced by genetic knockdown of KCC3
  JOURNAL   Cell Physiol Biochem 30 (2), 466-476 (2012)
   PUBMED   22776998
  REMARK    GeneRIF: Genetic silencing of KCC3 with short hairpin interfering
            RNA reduced protein expression by 40 - 60%, K(+) influx by ~50%,
            and cell motility by ~50%.
REFERENCE   6  (bases 1 to 6107)
  AUTHORS   Mercado A, Vazquez N, Song L, Cortes R, Enck AH, Welch R, Delpire
            E, Gamba G and Mount DB.
  TITLE     NH2-terminal heterogeneity in the KCC3 K+-Cl- cotransporter
  JOURNAL   Am J Physiol Renal Physiol 289 (6), F1246-F1261 (2005)
   PUBMED   16048901
REFERENCE   7  (bases 1 to 6107)
  AUTHORS   Davies SL, Roussa E, Le Rouzic P, Thevenod F, Alper SL, Best L and
            Brown PD.
  TITLE     Expression of K+-Cl- cotransporters in the alpha-cells of rat
            endocrine pancreas
  JOURNAL   Biochim Biophys Acta 1667 (1), 7-14 (2004)
   PUBMED   15533301
  REMARK    GeneRIF: distribution of KCC1, KCC3a, KCC3b, KCC4, and KCC2 protein
            and mrna in pancreatic alpha-cells and beta-cells; KCC's make a
            significant contribution to volume homeostasis only in alpha-cells
REFERENCE   8  (bases 1 to 6107)
  AUTHORS   Bergeron MJ, Gagnon E, Wallendorff B, Lapointe JY and Isenring P.
  TITLE     Ammonium transport and pH regulation by K(+)-Cl(-) cotransporters
  JOURNAL   Am J Physiol Renal Physiol 285 (1), F68-F78 (2003)
   PUBMED   12657561
REFERENCE   9  (bases 1 to 6107)
  AUTHORS   Pearson MM, Lu J, Mount DB and Delpire E.
  TITLE     Localization of the K(+)-Cl(-) cotransporter, KCC3, in the central
            and peripheral nervous systems: expression in the choroid plexus,
            large neurons and white matter tracts
  JOURNAL   Neuroscience 103 (2), 481-491 (2001)
   PUBMED   11246162
REFERENCE   10 (bases 1 to 6107)
  AUTHORS   Hiki K, D'Andrea RJ, Furze J, Crawford J, Woollatt E, Sutherland
            GR, Vadas MA and Gamble JR.
  TITLE     Cloning, characterization, and chromosomal location of a novel
            human K+-Cl- cotransporter
  JOURNAL   J Biol Chem 274 (15), 10661-10667 (1999)
   PUBMED   10187864
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473949.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001066528.1, XM_001066596.1, XM_001066706.1, XM_001066756.1,
            XM_001066648.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132291,
                              SAMD00132292 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..6107
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..6107
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /note="solute carrier family 12, member 6"
                     /db_xref="GeneID:691209"
                     /db_xref="RGD:1311335"
     exon            1..274
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             4..3456
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /note="furosemide-sensitive KCl cotransporter 3"
                     /codon_start=1
                     /product="solute carrier family 12 member 6"
                     /protein_id="NP_001103100.1"
                     /db_xref="GeneID:691209"
                     /db_xref="RGD:1311335"
                     /translation="MHPPETTTKMSSVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVR
                     FSSRESVPETSRSEPMSELSGATTSLATVALDPSSDRTSNPQDVTEDPNQNSITGEHS
                     QLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLT
                     QGAKEHEEAENITEGKKKPTKSPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVL
                     QAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGT
                     TFAAAMYILGAIEIFLVYIVPRAAIFRSDDALKESAAMLNNMRVYGTAFLVLMVLVVF
                     IGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHLDICSK
                     TKEVNNMTIPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSN
                     YLPKGEIIEKPSAKSSDVLGNLNHEYVLADITTSFTLLVGIFFPSVTGIMAGSNRSGD
                     LKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW
                     PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALL
                     LTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPHWRPRFRYYHWA
                     LSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARF
                     ALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVG
                     NFLENYGDALAAEQTIKHLMEAEKVKGFCQLVVAAKLKEGISHLIQSCGLGGMKHNTV
                     VMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNVSFFPSNVEQFSEGNIDVW
                     WIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAE
                     VEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSI
                     GSDEDEETETYQEKVHMTWTKDKYMASRGQKVKSMEGFQDLLNMRPDQSNVRRMHTAV
                     KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVI
                     TIYS"
     exon            275..319
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            320..414
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            415..546
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            547..693
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            694..748
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            749..879
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1121
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1336
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1495
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1594
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..1652
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1827
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1828..1946
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2045
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2046..2165
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2166..2270
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2271..2439
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2440..2635
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2636..2805
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2806..2937
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2938..3045
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3046..3230
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3231..3364
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3365..6107
                     /gene="Slc12a6"
                     /gene_synonym="Kcc3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaaatgcatc ctccagaaac caccaccaag atgtcttcag ttcggttcat ggtgacacca
       61 acaaagattg atgacattcc aggtttatca gacaccagtc cggacctcag ctctcgatct
      121 agttctcgag taagatttag ctcccgagaa agtgtgccag aaacaagccg tagtgagcct
      181 atgagtgaac tgtctggggc caccacttct ctggcaactg ttgccctaga tccttccagt
      241 gaccggactt ctaaccccca ggatgttacc gaggacccga atcagaactc catcacaggg
      301 gagcacagcc agctgttaga tgatggacat aagaaagctc gaaatgctta tctcaataat
      361 tccaactatg aagaaggaga cgaatatttt gataaaaatc tggcactctt tgaggaagaa
      421 atggacacca gaccaaaggt gtcttctctc ctcaaccgca tggccaacta tacaaatctg
      481 acacaaggag caaaggaaca tgaagaggca gagaacatca ccgaagggaa aaagaagcct
      541 accaagagcc cccaaatggg tactttcatg ggtgtctacc tcccatgtct acaaaatatt
      601 tttggagtga tcctctttct gcgtcttacc tgggtagtgg gcacagctgg agtccttcag
      661 gcctttgcca ttgtccttat ctgctgctgc tgtacaatgt taactgccat ctccatgagt
      721 gccatcgcca ctaacggagt ggtgccagct ggaggctcat acttcatgat ttcccgggcc
      781 ctgggcccag agtttggcgg ggctgtgggc ctctgctttt atcttggcac cacatttgca
      841 gcagccatgt atattcttgg tgccattgaa atctttctgg tgtatattgt cccccgagct
      901 gccatctttc ggagcgatga tgcactcaag gagtcagcag ccatgctgaa caacatgcgt
      961 gtctatggta cagccttcct ggtcctcatg gtcttggtgg tgttcatcgg cgtacgctat
     1021 gtgaataagt ttgcctcact tttcctggcc tgtgtaattg tgtcgatctt ggctatctat
     1081 gctggtgcca tcaagtcttc ctttgctcca ccacacttcc cggtctgtat gctgggcaac
     1141 cgcaccctgt catcaagaca ccttgacatt tgctctaaga ccaaggaagt taacaacatg
     1201 acaataccat caaagttatg gggattcttc tgcaactcaa gtcagttttt taatgccacc
     1261 tgtgatgagt actttgttca caataatgtc acctcaatcc agggcattcc agggttggct
     1321 agtggcatca ttactgaaaa cctttggagt aattatttac caaaaggtga gataattgaa
     1381 aagccatcag ccaagtcatc tgacgttttg ggcaacttaa accatgaata tgttcttgct
     1441 gatattacca cctccttcac tcttctggtg gggatcttct ttccttctgt cacaggtatc
     1501 atggctgggt caaacagatc tggagatctg aaagatgctc aaaagtctat ccccattggg
     1561 accatccttg ccatcctgac cacatccttc gtgtatttaa gcaatgttgt cctttttggt
     1621 gcatgtatcg aaggagttgt cctcagagac aaatttgggg atgctgtaaa agggaatttg
     1681 gttgtaggca ccttatcctg gccatcccca tgggtgattg ttattggctc cttcttttca
     1741 acgtgtggag ctggacttca gagcctcaca ggtgcacctc ggctgctgca ggctattgcc
     1801 aaggacaaca tcataccttt ccttagggtt tttggacaca gtaaagctaa tggggaacct
     1861 acctgggcct tacttctaac tgctgccata gcagagctgg gaattctcat cgcctccctg
     1921 gatctcgtgg ccccaattct ttccatgttt tttctcatgt gttacctctt tgtgaacttg
     1981 gcttgtgcct tgcaaacatt actgcgaacc ccccactgga ggcctcgatt ccgctactat
     2041 cactgggccc tctctttcat gggaatgagt atctgtctag ctctgatgtt catttcttct
     2101 tggtattatg ccattgtagc tatggtaata gctggcatga tctacaagta cattgaatac
     2161 caaggggctg aaaaagaatg gggcgatggt atccgtgggc tgtcactcag tgcagcccgc
     2221 ttcgctttgc tccgcctaga ggaaggccct cctcacacta aaaactggag gcctcagctg
     2281 cttgtactgc taaagctgga tgaagactta cacgtcaagc accctcgcct cctcaccttt
     2341 gcctcacagc tcaaggcagg aaagggactc accattgtgg gctctgtcat cgtggggaac
     2401 ttcctggaga actatggtga cgctctagca gcagagcaga ccattaagca cctcatggag
     2461 gcagaaaagg taaaagggtt ctgccagctg gtagtggctg ccaagctgaa agagggcatt
     2521 tcacacctca tccagtcctg tggccttgga ggcatgaagc acaacacagt ggtgatgggc
     2581 tggcccaatg gctggcgtca gagtgaagat gctcgtgctt ggaagacttt cattggcaca
     2641 gttcgagtga caactgctgc ccatctagcc ctgttagtgg ctaaaaatgt ctccttcttt
     2701 cccagcaatg tggaacaatt ttctgagggc aacattgatg tgtggtggat tgtgcatgat
     2761 gggggcatgc tcatgctatt accattccta ctgaaacagc acaaggtttg gcgaaaatgc
     2821 agcatacgga tcttcacagt agcccaacta gaagacaaca gtatccagat gaagaaggac
     2881 ctggccacct tcctgtacca tctgcgcatc gaggccgaag tggaagtggt ggagatgcat
     2941 gacagtgaca tatctgccta tacttatgag cgcaccctga tgatggagca gaggtcccag
     3001 atgcttcggc acatgcggct gtccaaaaca gaacgagata gagaggcaca actggtgaaa
     3061 gatcgaaact caatgcttcg cttaactagc attggctctg acgaggatga agaaacagaa
     3121 acttaccaag agaaggtgca catgacttgg accaaggata aatacatggc atcccggggg
     3181 caaaaggtca aatcaatgga aggattccaa gacctactta atatgcgtcc ggaccagtcc
     3241 aacgtgagac ggatgcatac agcagtgaag ctcaatgaag ttatagttaa caagtcccac
     3301 gaagcaaagc tggttttgtt gaatatgcca ggaccacccc gaaaccctga aggtgatgag
     3361 aactacatgg aatttctaga agtgctcact gagggattag agcgagtcct cctcgtccgg
     3421 ggtggtggca gtgaagtcat caccatatac tcatagtcat ctgtgggaga ctctgcgtga
     3481 tccgaccttt cccaagactc atggtcccat ggagatgaca gctctttcct accactccca
     3541 ctttgttctt gcagagctga gccccaacta tgctcttggc tgcaacatga tctgccatcc
     3601 cagcagaagc aaatattccc tcaacagaga atggtcaagt cctaaaagct atttctatgg
     3661 caggagaagg caagtcaaaa ttagcaagct aagccaaagg gaaccttttg gcacacagaa
     3721 ggtaatgagt tagaaaaaca tatgctagaa acttaactaa caacagaaaa caagttcata
     3781 tctaacattc aggacgagtc tcagaagaca caggtcagtg agcaccagaa agttaacagg
     3841 catttaagtc tcaccttagt aaaaagtgag ttaccattac agagatagcc tgcagcaagc
     3901 caggatagag acaaaggata ctgatacaca aaacctgaaa caaagctgca gcctctactt
     3961 cctcctcaaa acatagatcc cgcccccccc ccccccgtgt ttgattgtct gtactgcacc
     4021 actgtatact ttagctgtct ttgttttaaa cccattctgt ggttataatg cagacacgag
     4081 tcttacttta gaaatggttt tttgaaaggt aaaaatgttt tttcaggttt tctgagctaa
     4141 ggggattcca aagagtgcct gtaaaatgta tagaaacaca gtggttagct atgcaacaca
     4201 aagcacacaa gctattatcc aagaagtatg ggtggttatg tagttaacca gaagggtctc
     4261 ttctactctt agcaggcatt ggtctaacaa acaaaacctg tagggaagag acactcaact
     4321 gtgacaccac ctccacggcc ccaggattca gcggggtcca gcagtggaac tgggggtgtg
     4381 aaagccatac cctttccact gtgccaaaat catctgccca catgggcaga taggtttgca
     4441 tcagcctgac gcaagcacct tttctttcac aagaaatcaa tctgtggcct cttcaccaaa
     4501 gccatagtac agatttgagg cacttgacct ccatgcccag agctgagctt ttcccatttc
     4561 aatattattc actcttgact ccagaaactt ggctctgaaa caagtggttt gctgagccag
     4621 tgatctgctg tcttggtttt gttttccaaa agttctaagt gtgccaagga aatacttttg
     4681 taagctcgga ttcttttctt ttttttcttt cctaatttac tgatcacaaa cacttggctt
     4741 accagcatag gcagcctttg tggctgagca gtattttcaa gtatgtgaaa cccccatatc
     4801 ctttacatga tagttactta aaagactgtc ttcttgctta cttacattca tggctgcttt
     4861 taaatttcct ttcattgatg gtaaattgtg ccactctcca gaccctgtag gacaaggaac
     4921 ccagaattca gcccaagaca gaagaaaacc ctcaaatatg gcttggggag ctgaatcata
     4981 tggttggttc atcctcctcc caggccccct cgaggtagca caggatttag aatgttttcc
     5041 tttgcctcct gcagagggta gaaactgtac acagttctct ttccaacact ccattgcata
     5101 cttgagtgta atcgcctagg ctccaaggca ttaattgccc attctataaa agccagcctg
     5161 cccaggaact gcctaacaca tctacccctg accaaagtga tactttttcc atatcaaaca
     5221 aacatgggaa gagaataata agattacttt tagaaaggct gtttgtggtt agagctctgt
     5281 aagaatcttt taaagggtaa gagaatagtg gctattaata tagctattac ttcagtcccc
     5341 aagacaaaat cactgttaca tggaaaaatg gttattaggc cagatttata ctcatctctg
     5401 tctagaacat ttcatgtcta tgtgttgctt atgttgtctg tctgcaaagt gtcttatctt
     5461 ttaatcactg caaataaagc aatactgaaa acttgagaga gaaaatgcac cttaggggaa
     5521 ggggccaaat gtttctagag ggacgaggaa gaccttctcc tgccttcttt aaagacccag
     5581 cttttatgag tttagcaggg caggctgtaa cattcattct ctcccaactg gccctcagcc
     5641 tttcatagct accttaaaag ctggagtttg aattgcaggg cctgcttgac aggtgccagc
     5701 ttcttcatgg cagagaaaaa gtcgctgctt ttcacctttt gtttcctcct tttcttgtgg
     5761 ccccaggctc ccaccaatcc tcactcctta ctgtggatat taagttacac tgtaagctta
     5821 tttacatgct cttttcccct ggtttttctt gtcatcatgt ataatttgaa ttcagcggta
     5881 ccttctcaca tcttccaaaa aaagtctgct tatgtgatat agaagtgaaa tattaaaata
     5941 gatttaaggg gaacttgtga aacattaaag cattgttctc aaccatttaa tttattgaaa
     6001 ggagatgctg ctactcagcg gctgctagtc ttttgtttac atagagtctg gttttgtttg
     6061 ttttgctctg tgctgggaac ataaataaag ttttctacat tattttc
//
