LOCUS       NM_001008555            1808 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 10, member 4 (Slc10a4),
            mRNA.
ACCESSION   NM_001008555 XM_223361
VERSION     NM_001008555.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1808)
  AUTHORS   Larhammar,M., Patra,K., Blunder,M., Emilsson,L., Peuckert,C.,
            Arvidsson,E., Ronnlund,D., Preobraschenski,J., Birgner,C.,
            Limbach,C., Widengren,J., Blom,H., Jahn,R., Wallen-Mackenzie,A. and
            Kullander,K.
  TITLE     SLC10A4 is a vesicular amine-associated transporter modulating
            dopamine homeostasis
  JOURNAL   Biol Psychiatry 77 (6), 526-536 (2015)
   PUBMED   25176177
REFERENCE   2  (bases 1 to 1808)
  AUTHORS   Zelano,J., Mikulovic,S., Patra,K., Kuhnemund,M., Larhammar,M.,
            Emilsson,L., Leao,R.N. and Kullander,K.
  TITLE     The synaptic protein encoded by the gene Slc10A4 suppresses
            epileptiform activity and regulates sensitivity to cholinergic
            chemoconvulsants
  JOURNAL   Exp Neurol 239, 73-81 (2013)
   PUBMED   23022458
  REMARK    Erratum:[Exp Neurol. 2013 Sep;247:750. Leao, R [corrected to Leao,
            R N]]
REFERENCE   3  (bases 1 to 1808)
  AUTHORS   Burger,S., Doring,B., Hardt,M., Beuerlein,K., Gerstberger,R. and
            Geyer,J.
  TITLE     Co-expression studies of the orphan carrier protein Slc10a4 and the
            vesicular carriers VAChT and VMAT2 in the rat central and
            peripheral nervous system
  JOURNAL   Neuroscience 193, 109-121 (2011)
   PUBMED   21742018
  REMARK    GeneRIF: The results of this study suggested that Slc10a4 could be
            a novel vesicular transporter for cholinergic and/or various
            monoaminergic neurotransmitters in the central and peripheral
            nervous system.
            Erratum:[Neuroscience. 2012 Jun 14;212:226]
REFERENCE   4  (bases 1 to 1808)
  AUTHORS   Geyer,J., Fernandes,C.F., Doring,B., Burger,S., Godoy,J.R.,
            Rafalzik,S., Hubschle,T., Gerstberger,R. and Petzinger,E.
  TITLE     Cloning and molecular characterization of the orphan carrier
            protein Slc10a4: expression in cholinergic neurons of the rat
            central nervous system
  JOURNAL   Neuroscience 152 (4), 990-1005 (2008)
   PUBMED   18355966
  REMARK    GeneRIF: The orphan carrier protein Slc10a4 expression in
            cholinergic neurons of the rat central nervous sys.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Oct 3, 2022 this sequence version replaced NM_001008555.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY704415.1, AY825923.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN12840105
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-724               JAXUCZ010000014.1  35557161-35557884   c
            725-935             JAXUCZ010000014.1  35556242-35556452   c
            936-1808            JAXUCZ010000014.1  35552170-35553042   c
FEATURES             Location/Qualifiers
     source          1..1808
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..1808
                     /gene="Slc10a4"
                     /note="solute carrier family 10, member 4"
                     /db_xref="GeneID:305309"
                     /db_xref="RGD:1309536"
     exon            1..724
                     /gene="Slc10a4"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..1448
                     /gene="Slc10a4"
                     /note="bile acid transporter Slc10a4; Na(+)/bile acid
                     cotransporter 4; solute carrier family 10 (sodium/bile
                     acid cotransporter family), member 4"
                     /codon_start=1
                     /product="sodium/bile acid cotransporter 4"
                     /protein_id="NP_001008555.2"
                     /db_xref="GeneID:305309"
                     /db_xref="RGD:1309536"
                     /translation="MDGLDNTTLLLAPSSLLPDNLTLSPNASSTSASTLSPLPVTSSP
                     SPGLSLAPTPSIGFSPDLTPTPEPTSSSLAGGVAGQDSSTFPRPWIPHEPPFWDTPLN
                     HGLNVFVGAALCITMLGLGCTVDVNHFGAHVRRPVGALLAALCQFGFLPLLAFLLALA
                     FKLDEVAAVAVLLCGCCPGGNLSNLMSLLVDGDMNLSIIMTISSTLLALVLMPLCLWI
                     YSRAWINTPLVQLLPLGAVTLTLCSTLIPIGLGVFIRYKYNRVADYIVKVSLCSLLVT
                     LVVLFIMTGTMLGPELLASIPAAVYVVAIFMPLAGYASGYGLATLFHLPPNCKRTVCL
                     ETGSQNVQLCTAILKLAFPPRFIGSMYMFPLLYALFQSAEAGVFVLIYKMYGSEILHK
                     REALDEDDDTDISYKKLKEEELADTSYGTVGTDDLVLMETTQTSL"
     exon            725..935
                     /gene="Slc10a4"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1808
                     /gene="Slc10a4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgccagct gccgggcagc atgcacacgg gagcgacgac cggcccgccg caccgacgcc
       61 gcggggacgc ttgaccggac agacaggttg aagccgagga tagcccctgc agaccgcgcc
      121 tcggcgacag cgccatggac ggcctggaca acaccaccct gctccttgcc ccgtcctcgc
      181 tgctgcctga caacctcacc ctgtcgccta acgccagcag cacgagcgcc agcaccctct
      241 cgcctctgcc tgtcacttcc agtcccagtc ccgggctcag cctcgctccg actccgagca
      301 tcggcttcag tcccgacttg accccgactc cagagcccac gagcagcagc ctcgcgggcg
      361 gcgtggcagg ccaggactcc tccacctttc cccggccctg gatcccccac gagcccccat
      421 tctgggacac gccgctcaac cacgggctga acgtgttcgt gggcgccgcc ttgtgcatca
      481 ccatgctggg cctgggctgt accgtggacg tgaaccactt cggagcgcac gtccggcggc
      541 cggtgggcgc tctgctggct gctctctgcc agttcggctt cttgccgctg ctcgccttct
      601 tgctggccct cgccttcaag ctggatgagg tggccgcggt ggccgtactc ctgtgtggct
      661 gctgtcccgg tggaaatctc tccaatctca tgtccttgct ggtggatggt gacatgaatc
      721 tcagtatcat catgaccatt tcttccacac tcctggccct ggtgttgatg cccctctgcc
      781 tctggatcta cagccgggct tggatcaata cccctctggt gcagttactc cccctagggg
      841 ccgtcaccct gactctctgc agcactctca tccctattgg gctgggcgtc ttcattcgct
      901 acaagtacaa ccgggtggct gactacatcg tgaaggtttc cctgtgctct ctgctcgtga
      961 ctctggtggt tctcttcata atgaccggca ccatgttagg acccgaactg ctggcaagca
     1021 tccctgcagc cgtttatgtg gtggccattt ttatgcctct ggcgggctat gcctcgggtt
     1081 atggcttagc taccctcttc caccttccac ccaactgcaa gagaactgtg tgcctggaga
     1141 ccggaagtca gaacgtgcag ctctgtaccg cgattctcaa actggccttc cccccgcgct
     1201 tcataggcag catgtacatg ttccctttgc tttacgctct cttccagtca gcggaagcag
     1261 gggtgttcgt tttaatatac aaaatgtacg gaagcgagat actgcacaag cgagaggccc
     1321 tggatgaaga tgatgacaca gatatctctt ataagaaact aaaagaggag gagctggcag
     1381 acacctccta tggcaccgtg gggacagatg acttagtgtt gatggaaacc acccagactt
     1441 ccctctgaac ggggagatgc ccaggagtct ccatttggct gaaataccac tttgtgacca
     1501 tggtagtgcg tatgggtccc atccaggata aggatgggtt ggcgtttcct gtaacagatt
     1561 cgatcttccc actgtaatgt tgcacctcag tattaaccgt gtgtttttat aacccatcag
     1621 tgtcccaatg ttgctttcac ctggatcagc tagactgccg ccgcttcctc tgctcgagtg
     1681 tgctgtttgc tcttgtctgt ctgttttgcc cattccacca gcatcgctac agagggggtg
     1741 ggaggggagg gaaggggctg gaaatgtaga tgtctggtgc atacatgagt aaaattgtaa
     1801 aacagaaa
//
