LOCUS       NM_001130988            1703 bp    mRNA    linear   ROD 01-AUG-2023
DEFINITION  Rattus norvegicus stem-loop histone mRNA binding protein (Slbp),
            mRNA.
ACCESSION   NM_001130988 XM_001060131 XM_001061936
VERSION     NM_001130988.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1703)
  AUTHORS   Bansal N, Zhang M, Bhaskar A, Itotia P, Lee E, Shlyakhtenko LS, Lam
            TT, Fritz A, Berezney R, Lyubchenko YL, Stafford WF and Thapar R.
  TITLE     Assembly of the SLIP1-SLBP complex on histone mRNA requires
            heterodimerization and sequential binding of SLBP followed by SLIP1
  JOURNAL   Biochemistry 52 (3), 520-536 (2013)
   PUBMED   23286197
REFERENCE   2  (bases 1 to 1703)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1703)
  AUTHORS   Yang XC, Torres MP, Marzluff WF and Dominski Z.
  TITLE     Three proteins of the U7-specific Sm ring function as the molecular
            ruler to determine the site of 3'-end processing in mammalian
            histone pre-mRNA
  JOURNAL   Mol Cell Biol 29 (15), 4045-4056 (2009)
   PUBMED   19470752
REFERENCE   4  (bases 1 to 1703)
  AUTHORS   Sullivan KD, Mullen TE, Marzluff WF and Wagner EJ.
  TITLE     Knockdown of SLBP results in nuclear retention of histone mRNA
  JOURNAL   RNA 15 (3), 459-472 (2009)
   PUBMED   19155325
REFERENCE   5  (bases 1 to 1703)
  AUTHORS   Yang XC, Purdy M, Marzluff WF and Dominski Z.
  TITLE     Characterization of 3'hExo, a 3' exonuclease specifically
            interacting with the 3' end of histone mRNA
  JOURNAL   J Biol Chem 281 (41), 30447-30454 (2006)
   PUBMED   16912046
REFERENCE   6  (bases 1 to 1703)
  AUTHORS   Erkmann JA, Wagner EJ, Dong J, Zhang Y, Kutay U and Marzluff WF.
  TITLE     Nuclear import of the stem-loop binding protein and localization
            during the cell cycle
  JOURNAL   Mol Biol Cell 16 (6), 2960-2971 (2005)
   PUBMED   15829567
REFERENCE   7  (bases 1 to 1703)
  AUTHORS   Whitfield ML, Kaygun H, Erkmann JA, Townley-Tilson WH, Dominski Z
            and Marzluff WF.
  TITLE     SLBP is associated with histone mRNA on polyribosomes as a
            component of the histone mRNP
  JOURNAL   Nucleic Acids Res 32 (16), 4833-4842 (2004)
   PUBMED   15358832
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC167755.1.
            
            On or before Aug 13, 2008 this sequence version replaced
            XM_001060131.1, XM_001061936.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167755.1, EV767728.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1703
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1703
                     /gene="Slbp"
                     /note="stem-loop histone mRNA binding protein"
                     /db_xref="GeneID:681062"
                     /db_xref="RGD:1584682"
     exon            1..101
                     /gene="Slbp"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..870
                     /gene="Slbp"
                     /note="stem-loop binding protein"
                     /codon_start=1
                     /product="histone RNA hairpin-binding protein"
                     /protein_id="NP_001124460.1"
                     /db_xref="GeneID:681062"
                     /db_xref="RGD:1584682"
                     /translation="MACRPRSPPRYGSRRDGGASPRSPARWSLGRKRRADGRDRKPED
                     SEEGELQTADHRPESFTTPEGHKPRSRCSDWASAVEEDEMRTRVNKEIARYKRKLLIN
                     DFGRERKSSSGSSDSKESVSSVPADVETDESVLMRRQKQINYGKNTMAYDRYIKEVPR
                     HLRQPGIHPRTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIQPVDLGEM
                     ETEFTESSSESQTSSQDNFDVYAGTPTKVRHVDCQVEDEFDLEACLTEPLKDFSAMS"
     exon            102..218
                     /gene="Slbp"
                     /inference="alignment:Splign:2.1.0"
     exon            219..323
                     /gene="Slbp"
                     /inference="alignment:Splign:2.1.0"
     exon            324..383
                     /gene="Slbp"
                     /inference="alignment:Splign:2.1.0"
     exon            384..521
                     /gene="Slbp"
                     /inference="alignment:Splign:2.1.0"
     exon            522..671
                     /gene="Slbp"
                     /inference="alignment:Splign:2.1.0"
     exon            672..753
                     /gene="Slbp"
                     /inference="alignment:Splign:2.1.0"
     exon            754..1656
                     /gene="Slbp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgaggttcct gctggtgagc tctccttcaa accaccgccg ccatggcctg cagacctaga
       61 agcccacccc gttacgggag tcgccgcgac ggcggtgcga gcccgcggtc tcctgcgcga
      121 tggagtctcg gacggaagcg cagagcggac ggaagagacc ggaagcctga ggactccgag
      181 gaaggcgagc tccagactgc agaccatcga cctgaaagct ttacaacgcc tgaaggccat
      241 aagccccgtt ctagatgttc tgactgggca agcgcagttg aagaagatga aatgaggacc
      301 agagttaaca aagagattgc aaggtacaaa agaaagctac tcataaatga ctttggaaga
      361 gagagaaaat cgtcatcagg aagttctgat tcaaaggagt ctgtgtcttc agtgcctgct
      421 gacgtggaga cagatgaaag tgtcttgatg agaaggcaga agcagatcaa ctatgggaag
      481 aacactatgg cctatgatcg atacattaaa gaggtgccca gacacctgcg acagcctgga
      541 atccatccca ggacccccaa caaatttaag aagtatagcc ggcggtcatg ggaccagcag
      601 atcaaactct ggaaggtggc tttgcatttt tgggatcctc ctgctgaaga agggtgtgat
      661 ttgcaagaaa tacaacctgt agatcttggg gaaatggaga cagaattcac agaaagcagc
      721 tctgagtccc agacaagttc acaggataac tttgatgtat atgctggcac acccaccaaa
      781 gtcagacatg tggactgcca agtggaggac gagtttgatt tggaagcttg tttaactgaa
      841 cctttgaaag acttctctgc catgagttaa ctgccccctg gtggttactc tgagaaatac
      901 ttggctctgc ctggctgcct ggaaggcatg agttgctgtg catttgtatt tgttttctct
      961 gttaagaatt tattttctca tgataaatag tttttcttgc cttattttta tgtatggtga
     1021 atgtgttacg catgttttaa attgtaaatg aagctgaatc cagtgaagac ttaaccctat
     1081 tacctttctg cctcctaagt tagacaacag gatgcgtgtg gttttctacc agaacttggg
     1141 actccagcta ccacgtttca aatgggttgg ccacggattt taaccgtgtg tttatgggac
     1201 caatttagaa ttggctgccc tttaggtaac tgatgaagaa ttctcagtca ggcagctgca
     1261 gtgactttgt aaaaacttat tttctggtct tttatcaatg tgaatgtagc tttccctcat
     1321 acagagctct gagcaaagat gttaagctgt tatattaatg ggcttttatg taagttatat
     1381 agttttaatt tggaacttga aatagcatta gtgtgaggta agtattttag taaatgctct
     1441 gtgagttgat gcagaagaga ggaagagagg gatttagaaa gaactttgtt tttttttttt
     1501 ttttttaatg atcagttaat ttaccatgta atattgctgt aaatgatgtg tacagataac
     1561 tctgttcatg tattcaattg taaacttgtc aatatttgca tttctattgc ttttgtatgg
     1621 aatgataatt gcaaaaataa agatgcttta actgataaaa aaaaaaaaaa aaaaaaaaaa
     1681 aaaaaaaaaa aaaaaaaaaa aaa
//
