LOCUS       NP_001178861             343 aa            linear   ROD 31-MAR-2024
DEFINITION  SLAM family member 6 precursor [Rattus norvegicus].
ACCESSION   NP_001178861 XP_573514
VERSION     NP_001178861.1
DBSOURCE    REFSEQ: accession NM_001191932.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 343)
  AUTHORS   Chatterjee,M., Rauen,T., Kis-Toth,K., Kyttaris,V.C., Hedrich,C.M.,
            Terhorst,C. and Tsokos,G.C.
  TITLE     Increased expression of SLAM receptors SLAMF3 and SLAMF6 in
            systemic lupus erythematosus T lymphocytes promotes Th17
            differentiation
  JOURNAL   J Immunol 188 (3), 1206-1212 (2012)
   PUBMED   22184727
REFERENCE   2  (residues 1 to 343)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (residues 1 to 343)
  AUTHORS   Griewank,K., Borowski,C., Rietdijk,S., Wang,N., Julien,A.,
            Wei,D.G., Mamchak,A.A., Terhorst,C. and Bendelac,A.
  TITLE     Homotypic interactions mediated by Slamf1 and Slamf6 receptors
            control NKT cell lineage development
  JOURNAL   Immunity 27 (5), 751-762 (2007)
   PUBMED   18031695
REFERENCE   4  (residues 1 to 343)
  AUTHORS   Eissmann,P. and Watzl,C.
  TITLE     Molecular analysis of NTB-A signaling: a role for EAT-2 in
            NTB-A-mediated activation of human NK cells
  JOURNAL   J Immunol 177 (5), 3170-3177 (2006)
   PUBMED   16920955
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Jul 17, 2010 this sequence version replaced XP_573514.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.16644.1,
                                           SRR26643292.50134.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680412, SAMN06680413
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     Protein         1..343
                     /product="SLAM family member 6 precursor"
                     /calculated_mol_wt=35297
     sig_peptide     1..29
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=3218
     Region          43..144
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          50..54
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          64..68
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          108..112
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          122..127
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          136..139
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..343
                     /gene="Slamf6"
                     /gene_synonym="RGD1561848"
                     /coded_by="NM_001191932.1:1..1032"
                     /db_xref="GeneID:498287"
                     /db_xref="RGD:1561848"
ORIGIN      
        1 mavsrapahd sarqrmvwlf plvfclgtgs dvpqsssnpr lmngilgesi vlplelpagk
       61 iasvivwshk ealqgtimfi iqlkepekpn iinanrekek rlnitqsysl qlnnltmadt
      121 gsytaqitte dteptifryt lrvferlsnl eianhtllle ngtcqmylac tvknsnqtvs
      181 fewqttgnis lrepnvtisw dprnssnqty icraenavsn lsvsvstqsl ckdltnqpwt
      241 kaqltaiisi pmvvvipvfl ymciylwkrr rgslpltrqh pdssqssdtp gspgntvyaq
      301 vshpmqemki qnpikndsmt iysivnhsre pvsprlntlk dik
//
