LOCUS       NM_001109078            2731 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Rattus norvegicus signaling lymphocytic activation molecule family
            member 1 (Slamf1), mRNA.
ACCESSION   NM_001109078 XM_001054873 XM_573513
VERSION     NM_001109078.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Liu,M., Jiang,Z., Liu,M., Ni,H., Li,Y., Fang,J., Du,Q. and Dong,Y.
  TITLE     SLAMF1 as a novel molecule mediating the causal association between
            rheumatoid arthritis and interstitial lung disease: A Mendelian
            randomization study combined with transcriptomics and in vivo
            validation
  JOURNAL   Int Immunopharmacol 142 (Pt A), 113082 (2024)
   PUBMED   39260308
  REMARK    GeneRIF: SLAMF1 as a novel molecule mediating the causal
            association between rheumatoid arthritis and interstitial lung
            disease: A Mendelian randomization study combined with
            transcriptomics and in vivo validation.
REFERENCE   2  (bases 1 to 2731)
  AUTHORS   Rabenhorst,U., Thalheimer,F.B., Gerlach,K., Kijonka,M., Bohm,S.,
            Krause,D.S., Vauti,F., Arnold,H.H., Schroeder,T., Schnutgen,F., von
            Melchner,H., Rieger,M.A. and Zornig,M.
  TITLE     Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is
            Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal
  JOURNAL   Cell Rep 11 (12), 1847-1855 (2015)
   PUBMED   26095368
REFERENCE   3  (bases 1 to 2731)
  AUTHORS   Wang,G., van Driel,B.J., Liao,G., O'Keeffe,M.S., Halibozek,P.J.,
            Flipse,J., Yigit,B., Azcutia,V., Luscinskas,F.W., Wang,N. and
            Terhorst,C.
  TITLE     Migration of myeloid cells during inflammation is differentially
            regulated by the cell surface receptors Slamf1 and Slamf8
  JOURNAL   PLoS One 10 (3), e0121968 (2015)
   PUBMED   25799045
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2731)
  AUTHORS   Gustafsson,K., Heffner,G., Wenzel,P.L., Curran,M., Grawe,J.,
            McKinney-Freeman,S.L., Daley,G.Q. and Welsh,M.
  TITLE     The Src homology 2 protein Shb promotes cell cycle progression in
            murine hematopoietic stem cells by regulation of focal adhesion
            kinase activity
  JOURNAL   Exp Cell Res 319 (12), 1852-1864 (2013)
   PUBMED   23528453
REFERENCE   5  (bases 1 to 2731)
  AUTHORS   van Driel,B., Liao,G., Romero,X., O'Keeffe,M.S., Wang,G.,
            Faubion,W.A., Berger,S.B., Magelky,E.M., Manocha,M., Azcutia,V.,
            Grisham,M., Luscinskas,F.W., Mizoguchi,E., de Waal Malefyt,R.,
            Reinecker,H.C., Bhan,A.K., Wang,N. and Terhorst,C.
  TITLE     Signaling lymphocyte activation molecule regulates development of
            colitis in mice
  JOURNAL   Gastroenterology 143 (6), 1544-1554 (2012)
   PUBMED   22960654
REFERENCE   6  (bases 1 to 2731)
  AUTHORS   Levi,B.P., Yilmaz,O.H., Duester,G. and Morrison,S.J.
  TITLE     Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in
            the mouse hematopoietic and nervous systems
  JOURNAL   Blood 113 (8), 1670-1680 (2009)
   PUBMED   18971422
REFERENCE   7  (bases 1 to 2731)
  AUTHORS   Griewank,K., Borowski,C., Rietdijk,S., Wang,N., Julien,A.,
            Wei,D.G., Mamchak,A.A., Terhorst,C. and Bendelac,A.
  TITLE     Homotypic interactions mediated by Slamf1 and Slamf6 receptors
            control NKT cell lineage development
  JOURNAL   Immunity 27 (5), 751-762 (2007)
   PUBMED   18031695
REFERENCE   8  (bases 1 to 2731)
  AUTHORS   Rethi,B., Gogolak,P., Szatmari,I., Veres,A., Erdos,E., Nagy,L.,
            Rajnavolgyi,E., Terhorst,C. and Lanyi,A.
  TITLE     SLAM/SLAM interactions inhibit CD40-induced production of
            inflammatory cytokines in monocyte-derived dendritic cells
  JOURNAL   Blood 107 (7), 2821-2829 (2006)
   PUBMED   16317102
REFERENCE   9  (bases 1 to 2731)
  AUTHORS   Latour,S., Gish,G., Helgason,C.D., Humphries,R.K., Pawson,T. and
            Veillette,A.
  TITLE     Regulation of SLAM-mediated signal transduction by SAP, the
            X-linked lymphoproliferative gene product
  JOURNAL   Nat Immunol 2 (8), 681-690 (2001)
   PUBMED   11477403
REFERENCE   10 (bases 1 to 2731)
  AUTHORS   Aversa,G., Chang,C.C., Carballido,J.M., Cocks,B.G. and de
            Vries,J.E.
  TITLE     Engagement of the signaling lymphocytic activation molecule (SLAM)
            on activated T cells results in IL-2-independent, cyclosporin
            A-sensitive T cell proliferation and IFN-gamma production
  JOURNAL   J Immunol 158 (9), 4036-4044 (1997)
   PUBMED   9126961
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473985.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_573513.2, XM_001054873.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN09345330,
                              SAMN09345331 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..2731
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /note="signaling lymphocytic activation molecule family
                     member 1"
                     /db_xref="GeneID:498286"
                     /db_xref="RGD:1560634"
     exon            1..159
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..1121
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /codon_start=1
                     /product="signaling lymphocytic activation molecule
                     precursor"
                     /protein_id="NP_001102548.1"
                     /db_xref="GeneID:498286"
                     /db_xref="RGD:1560634"
                     /translation="MDPNRSLSLRILLFLSLAVELSYGTGTGMMDCPVILQELGRDTW
                     LALTNEHQINKSANKSIRILVTMARSPGSKTNKKIVSFDLSKGGYPDHLEDGYQFQSK
                     NLSLKILGNRRESEGLYFVTVEENVSVHQSCTQLKLYEQVSTPEIKVLNKTQEENGTC
                     HLLLACTVKRGDNVSYSWGDEAGTRLPSQANRSHLLHLILSNQHQDSIYNCTASNPVS
                     SRSRTFNLWQQCRPESYSESSLWLPYIAAPLGVIIFVILVSIATVLVKRYWAPSGKPN
                     HCQPPVEEKSLTIYAQVQKSGPLEKELHDALTDQDPCTTIYVAATEPVPESVQEPNPT
                     TVYASVTLPES"
     exon            160..501
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /inference="alignment:Splign:2.1.0"
     exon            502..792
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /inference="alignment:Splign:2.1.0"
     exon            793..900
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /inference="alignment:Splign:2.1.0"
     exon            901..974
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1070
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..2731
                     /gene="Slamf1"
                     /gene_synonym="RGD1560634"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgatcagagc ttctgcctgg ggggtaacag taagcagctg ccgagctccc agccgggcac
       61 ccggttcctc tctttgctgg gtcatggatc ccaaccgatc cctttccttg agaatacttc
      121 tgtttctctc cctggctgtt gagttgagct acggaacagg tacaggtatg atggactgcc
      181 cggtgattct ccaggagctg ggacgtgaca catggctggc cctgacaaat gaacatcaga
      241 ttaataagag cgcgaacaaa agcatccgca tccttgtcac gatggcaagg tctccaggaa
      301 gcaaaaccaa caagaaaata gtgtcttttg atctctcgaa agggggctac ccagatcacc
      361 tggaggatgg ctaccagttt caatccaaaa acctaagcct gaagatccta gggaacagga
      421 gggagagtga aggcttgtac tttgtgaccg tggaagagaa cgtgtcagtc catcaatcct
      481 gcacgcaact gaagctttat gaacaggtct ccactccaga gattaaagtg ctaaacaaaa
      541 cccaggagga gaatgggacc tgccacttgc tgctagcctg cacggtgaag agaggggata
      601 atgtgtctta cagctggggt gatgaggcag gtacccgtct gccaagccaa gccaaccgct
      661 cccacctcct gcacctcatc cttagcaacc agcatcagga cagcatctac aactgcacag
      721 cgagcaatcc tgtcagcagt cgctctcgga ccttcaacct atggcagcaa tgcaggccag
      781 aatcctactc agaatcgagt ctgtggcttc cgtatattgc tgcaccatta ggggtcatca
      841 tattcgtcat cctggtttcc atagcaacag tattggtgaa aagatactgg gctcccagtg
      901 gtaaaccaaa tcactgccag ccacctgtag aagaaaaaag ccttactatc tatgcccaag
      961 tacagaaatc agggcctcta gagaaggaac ttcatgatgc cctgacagat caggacccct
     1021 gcacgaccat ttatgtggct gccacagagc ctgtcccaga atctgtccag gaaccaaacc
     1081 ccaccacagt ttatgccagt gtgacactgc cagagagctg acccatagac ccagtggaag
     1141 gactttttga aggaggatag aagaatggaa atccacactg aactgggctc cgggtcccaa
     1201 gttctctgtg gcagatactg cacatctgta cccttctcca atcagttccc tggtaatgga
     1261 tctgcacagg catgcctgcg aagtcgatgg ggaagtgagg cttctggggc atgtagcctg
     1321 ctctgcagct ggcacggaga ttcctcatat ggcattccat cagttaaaat gcataacgtg
     1381 agttcaggca tctcactctt tgcctggttc aataacagaa cccaaagacg acgacgacga
     1441 caacaacaac aacaacaata acaacaacaa caacaaacaa ggacatagac tatctcagat
     1501 ggctgagcac aaggtacaag gactggagat gttttcattt tgactctcgc tactttactc
     1561 tggaagctga tcctgatcac ctcaagacca agggctctgt gcctcagttt ctctctcgcc
     1621 ctctagataa agagggaaga aaacataaag aatgaagtct ttgttgtctg agatcattct
     1681 ataaaagaac cgatatttta tctgcaaaat gcaagctggt aaaactcagt agacttgaag
     1741 atgattttgg agcctcttaa gcttcagaca acagaatgga atccatctac ggttcttcca
     1801 gttgtggttg tcagcaagca gcattctgct taaaccaaag caaccatgtt tggtcatgct
     1861 cttgtaaagt tgcctgggat actcagagga acttgtccca gggaggtttt ttcacttctt
     1921 caaagaactt ttgaatttaa gttctctggt tgaatttgct ctcccttgag caaaactctg
     1981 aatcctcaag attctctctc cattggctct gaggccattt tataacacag gcctcctgtg
     2041 gaactgcagg tccaccgcct gcttcctatc tcactgcgta cctctgtgta gtagtaaatt
     2101 aaaccacaag tgaaacatta aattattttg attgaacagt tccaaatgat tagatgttca
     2161 gtctcttcaa taacaggttg tgggtagaaa agtactacgt aaagtcctat tttcttcatg
     2221 ctgtctatcc tcagagaggc catcttccca tttattgtcc ttcttgcaca actttggcaa
     2281 atactttaaa aataaccatt gtggagatgg ttactaagtg gataatagca cttgctttgc
     2341 aaacatgaag agctgggtgc aaactcctag tgtccgtgca aaaaaagatg ggtgtggctg
     2401 agtgtacctg taacacagag atagacaggt cctgagacct tgctccttag ccttcccagc
     2461 ctggcataaa tgtcaagtcc ccctgagaat gacagaggaa gacactcccc tccacacgca
     2521 catagtgata cacatacaca tgcatataaa aaaaccccat tgtatcattg cataacaaag
     2581 aacatcaact gcccagctca aaactctgat ggcccattac cctgtacctt tctgtattta
     2641 gataatttac agtgaagtct tgttgctcca tgtatcctat gttgtgttac taacttatat
     2701 caaagtattt ctaattataa tcaacaaaag c
//
