LOCUS       NM_001172118            1076 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus Src-like-adaptor 2 (Sla2), mRNA.
ACCESSION   NM_001172118
VERSION     NM_001172118.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1076)
  AUTHORS   Loreto,M.P., Berry,D.M. and McGlade,C.J.
  TITLE     Functional cooperation between c-Cbl and Src-like adaptor protein 2
            in the negative regulation of T-cell receptor signaling
  JOURNAL   Mol Cell Biol 22 (12), 4241-4255 (2002)
   PUBMED   12024036
REFERENCE   2  (bases 1 to 1076)
  AUTHORS   Pandey,A., Ibarrola,N., Kratchmarova,I., Fernandez,M.M.,
            Constantinescu,S.N., Ohara,O., Sawasdikosol,S., Lodish,H.F. and
            Mann,M.
  TITLE     A novel Src homology 2 domain-containing molecule, Src-like adapter
            protein-2 (SLAP-2), which negatively regulates T cell receptor
            signaling
  JOURNAL   J Biol Chem 277 (21), 19131-19138 (2002)
   PUBMED   11891219
REFERENCE   3  (bases 1 to 1076)
  AUTHORS   Holland,S.J., Liao,X.C., Mendenhall,M.K., Zhou,X., Pardo,J.,
            Chu,P., Spencer,C., Fu,A., Sheng,N., Yu,P., Pali,E., Nagin,A.,
            Shen,M., Yu,S., Chan,E., Wu,X., Li,C., Woisetschlager,M.,
            Aversa,G., Kolbinger,F., Bennett,M.K., Molineaux,S., Luo,Y.,
            Payan,D.G., Mancebo,H.S. and Wu,J.
  TITLE     Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel
            inhibitor of antigen receptor signaling
  JOURNAL   J Exp Med 194 (9), 1263-1276 (2001)
   PUBMED   11696592
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.5088.1,
                                           SRR26643292.15298.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                JAXUCZ010000003.1  165841952-165842048 c
            98-197              JAXUCZ010000003.1  165838796-165838895 c
            198-284             JAXUCZ010000003.1  165838367-165838453 c
            285-388             JAXUCZ010000003.1  165837627-165837730 c
            389-538             JAXUCZ010000003.1  165830451-165830600 c
            539-671             JAXUCZ010000003.1  165829674-165829806 c
            672-1076            JAXUCZ010000003.1  165828657-165829061 c
FEATURES             Location/Qualifiers
     source          1..1076
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..1076
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /note="Src-like-adaptor 2"
                     /db_xref="GeneID:499931"
                     /db_xref="RGD:1562071"
     CDS             1..792
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /codon_start=1
                     /product="src-like-adapter 2"
                     /protein_id="NP_001165589.1"
                     /db_xref="GeneID:499931"
                     /db_xref="RGD:1562071"
                     /translation="MMGSLPSRGKNSSPSSSSSFSGPGQEPVSIQAERQKVSAVALGS
                     FPAGEQARLSLRVGEPLTIISEDGDWWTVQSEVSGREYHIPSVYVAKVSHGWLYEGLS
                     REKAEELLLLPGNPGGAFLIRESQTRRGCYSLSIRLSRPASWDRIRHYRIQRLDNGWL
                     YISPRLTFPSLHALVEHYSELADGICCALREPCVLQKLGPLPGKDTPLPVTVPTSSLN
                     WKKLDRSLLCLDAPASGEASLLSEGLRESLSSYISLTEETALDDA"
     exon            1..97
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /inference="alignment:Splign:2.1.0"
     exon            98..197
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /inference="alignment:Splign:2.1.0"
     exon            198..284
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /inference="alignment:Splign:2.1.0"
     exon            285..388
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /inference="alignment:Splign:2.1.0"
     exon            389..538
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /inference="alignment:Splign:2.1.0"
     exon            539..671
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /inference="alignment:Splign:2.1.0"
     exon            672..1076
                     /gene="Sla2"
                     /gene_synonym="RGD1562071"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgatgggaa gtttgcccag cagagggaaa aactccagcc caagctccag ttccagcttc
       61 tctggtccag gccaggaacc tgtgtccata caagcagaaa gacagaaggt ctcagctgtg
      121 gccctgggca gtttcccagc aggtgagcag gccagactat ctctgagagt cggggaacca
      181 ctgaccatca tatctgagga tggagattgg tggacagtcc agtcggaagt ctcaggcaga
      241 gagtatcata tccccagtgt gtatgtggct aaagtctccc acgggtggct gtatgagggc
      301 ctgagtcggg agaaagctga ggaacttctc ttattacctg ggaaccccgg aggagccttc
      361 ctcatcaggg agagccagac caggagaggc tgctattccc tgtccatccg cctcagtcgc
      421 cctgcttctt gggaccggat cagacactac aggatacagc gtcttgacaa tggctggctg
      481 tacatctcac ctcgcctcac cttcccctca ctccacgccc tggtggaaca ttactctgag
      541 ctagcagatg gcatctgctg tgccctcagg gagccctgtg tcctgcagaa gcttgggcca
      601 ctacctggca aagatacacc tctacctgtg actgtgccaa cgtcatcact gaattggaaa
      661 aagctagaca ggagcctcct gtgtttggac gcacctgcca gtggggaggc gtctcttctc
      721 agtgagggcc tccgggagtc cctcagctcc tacatcagcc tgactgagga gaccgccttg
      781 gacgatgcct agtcctgaag ctggaagcta aagggaacca aggcagtggc acctacaact
      841 ctaacttggc tgaccctgac aaagctcccc agaggcaagg ctgtgaaagc agacggtggg
      901 ggtggggaca cacattcagg gcctcacctg gaccttctga taagcctgga tcttcttcca
      961 aggcctcatc cctgcctata agttctagtc tgtgtgcagc gcagttcaaa gcagggccag
     1021 gcctgtacgg agagcaagag acttctgagg tctggtaagt cacttcctga gaggaa
//
