LOCUS       NM_001025743            1232 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus SKI8 subunit of superkiller complex (Skic8),
            mRNA.
ACCESSION   NM_001025743 XM_343392
VERSION     NM_001025743.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Strikoudis,A., Lazaris,C., Trimarchi,T., Galvao Neto,A.L., Yang,Y.,
            Ntziachristos,P., Rothbart,S., Buckley,S., Dolgalev,I.,
            Stadtfeld,M., Strahl,B.D., Dynlacht,B.D., Tsirigos,A. and
            Aifantis,I.
  TITLE     Regulation of transcriptional elongation in pluripotency and cell
            differentiation by the PHD-finger protein Phf5a
  JOURNAL   Nat Cell Biol 18 (11), 1127-1138 (2016)
   PUBMED   27749823
REFERENCE   2  (bases 1 to 1232)
  AUTHORS   Muntean,A.G., Tan,J., Sitwala,K., Huang,Y., Bronstein,J.,
            Connelly,J.A., Basrur,V., Elenitoba-Johnson,K.S. and Hess,J.L.
  TITLE     The PAF complex synergizes with MLL fusion proteins at HOX loci to
            promote leukemogenesis
  JOURNAL   Cancer Cell 17 (6), 609-621 (2010)
   PUBMED   20541477
REFERENCE   3  (bases 1 to 1232)
  AUTHORS   Jaehning,J.A.
  TITLE     The Paf1 complex: platform or player in RNA polymerase II
            transcription?
  JOURNAL   Biochim Biophys Acta 1799 (5-6), 379-388 (2010)
   PUBMED   20060942
  REMARK    Review article
REFERENCE   4  (bases 1 to 1232)
  AUTHORS   Kim,J., Guermah,M. and Roeder,R.G.
  TITLE     The human PAF1 complex acts in chromatin transcription elongation
            both independently and cooperatively with SII/TFIIS
  JOURNAL   Cell 140 (4), 491-503 (2010)
   PUBMED   20178742
REFERENCE   5  (bases 1 to 1232)
  AUTHORS   Zhu,B., Mandal,S.S., Pham,A.D., Zheng,Y., Erdjument-Bromage,H.,
            Batra,S.K., Tempst,P. and Reinberg,D.
  TITLE     The human PAF complex coordinates transcription with events
            downstream of RNA synthesis
  JOURNAL   Genes Dev 19 (14), 1668-1673 (2005)
   PUBMED   16024656
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098059.1.
            
            On Jul 22, 2005 this sequence version replaced XM_343392.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098059.1, SRR8487230.9852.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1232
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /note="SKI8 subunit of superkiller complex"
                     /db_xref="GeneID:363064"
                     /db_xref="RGD:1308228"
     exon            1..66
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            67..117
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..1023
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /note="WD repeat-containing protein 61; WD repeat domain
                     61; SKI8 subunit of superkiller complex protein"
                     /codon_start=1
                     /product="superkiller complex protein 8"
                     /protein_id="NP_001020914.1"
                     /db_xref="GeneID:363064"
                     /db_xref="RGD:1308228"
                     /translation="MTNQYSILFKQEQAHDDAIWSVAWETNKKENIETVVTGSLDDLV
                     KVWKWRDERLELQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQMKSI
                     DAGPVDAWTLAFSPDSQHLATGTHMGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDG
                     KYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYD
                     VQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCIHTFFDHQDQ
                     VWGVKYNGNGSKIVSVGDDQEIHVYDCPI"
     exon            118..145
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            146..251
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            252..424
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            425..573
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            574..667
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            668..761
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            762..854
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            855..933
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1206
                     /gene="Skic8"
                     /gene_synonym="RGD1308228; Ski8; Wdr61"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttggtgctgc tgcttactag cgtgggaagg cgagtgaaca ggaaggattg gaggccgcca
       61 ctgcagaact gtctggcctt tagctcttca tctttggtta aggaaatgac caaccagtac
      121 agtattctct tcaagcaaga gcaagcccac gatgatgcca tatggtcggt tgcctgggag
      181 acaaacaaaa aggaaaacat tgaaacagtg gtcacaggat ccctggatga tctggtgaag
      241 gtctggaaat ggcgtgatga gaggctggag ctgcagtgga gcctggaggg acatcagctt
      301 ggtgtggtgt ctgtcgacat cagccacacc cttcccattg ctgcctccag ttctctagat
      361 gctcatattc gactctggga cttggaaaat ggcaaacaga tgaagtctat agatgcagga
      421 ccggtggatg cctggacttt ggcattctct ccggactccc agcatctggc aacaggaact
      481 cacatgggga aagtgaacat ttttggtgtg gaaagtggaa aaaaagaata ctctttggac
      541 actagaggaa aattcatcct tagcattgca tatagtcctg atggaaaata cctggccagc
      601 ggagccatag acgggatcat caatattttt gatattgcaa ctggaaagct tctgcacacg
      661 ctggaaggcc atgcgatgcc cattcgatcc ttgacctttt cccctgactc ccagctcctc
      721 gtcacggctt cagatgatgg ctacatcaag atctatgatg tgcaacatgc caatttggct
      781 ggcacactga gtggccatgc atcctgggta ttgaatgttg cgttctgtcc agatgacact
      841 cactttgttt ccagttcatc cgacaaaagt gtaaaggtct gggatgttgg aacaaggacc
      901 tgtattcaca ccttctttga ccaccaggat caggtttggg gagtaaaata taatggaaat
      961 ggatcaaaaa ttgtgtctgt tggagatgac caggagatcc atgtctatga ctgcccaatt
     1021 taaacaccag catcttcagg gccagtgcct cagactacgc agggttgata ggacattcct
     1081 cagctttttt ggcacactta aagtacagca tatattgtag aaattttgta gatacaatat
     1141 aaattgttcc tgttttattg gaaatgtaac tcatatttta atgtaaataa agcattctta
     1201 atgcaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
