LOCUS       NM_001108032            3999 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus SIX homeobox 6 (Six6), mRNA.
ACCESSION   NM_001108032 XM_001080657 XM_234288
VERSION     NM_001108032.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3999)
  AUTHORS   Jeong,Y., Leskow,F.C., El-Jaick,K., Roessler,E., Muenke,M.,
            Yocum,A., Dubourg,C., Li,X., Geng,X., Oliver,G. and Epstein,D.J.
  TITLE     Regulation of a remote Shh forebrain enhancer by the Six3
            homeoprotein
  JOURNAL   Nat Genet 40 (11), 1348-1353 (2008)
   PUBMED   18836447
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473947.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001080657.1, XM_234288.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB740799.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840117, SAMN12840127
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3999
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..3999
                     /gene="Six6"
                     /note="SIX homeobox 6"
                     /db_xref="GeneID:314221"
                     /db_xref="RGD:1310497"
     exon            1..735
                     /gene="Six6"
                     /inference="alignment:Splign:2.1.0"
     CDS             164..904
                     /gene="Six6"
                     /note="sine oculis-related homeobox 6 homolog"
                     /codon_start=1
                     /product="homeobox protein SIX6"
                     /protein_id="NP_001101502.1"
                     /db_xref="GeneID:314221"
                     /db_xref="RGD:1310497"
                     /translation="MFQLPILNFSPQQVAGVCETLEESGDVERLGRFLWSLPVAPAAC
                     EALNKNESVLRARAIVAFHGGNYRELYHILENHKFTKESHAKLQALWLEAHYQEAEKL
                     RGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRHLLREWYLQDPYPNPSKKRE
                     LAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQQQVLSQGPGRVLRSEGEGTPEVLGV
                     ASSPAASLSSKAATSAISITSSDSECDI"
     exon            736..3999
                     /gene="Six6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atctagctgg ctggcgtgtc ctagctgagc aagcgcagcc gaacccaacc cacatctctt
       61 ccaggcggga aggctccccc ccgactttgt aacccccagc cgcaccccgc tcggccggcg
      121 ggcatctgct gcctgtcccg cccggggcgc ccgcgcagcc tcgatgttcc agctgcccat
      181 tttgaatttc agcccccagc aagtagccgg ggtatgcgag accctggagg aaagcggcga
      241 cgtggagcgc ctcggtcgct tcctgtggtc gctgcccgtg gccccggcag cctgtgaggc
      301 cctcaacaaa aatgagtcgg tgctgcgcgc gagagccatc gtggccttcc acggtggcaa
      361 ctaccgcgag ctctaccaca ttctggaaaa tcataagttt actaaggaat cgcacgccaa
      421 gctgcaggca ctgtggctcg aagctcatta ccaggaggca gagaagctgc gtggacgacc
      481 cctggggcca gtagacaagt accgggtaag gaagaagttc ccgctgccgc ggaccatttg
      541 ggatggcgaa cagaagactc actgcttcaa ggagcgcaca cggcacctgc ttcgagagtg
      601 gtaccttcag gacccatatc ccaaccccag caaaaagcga gagctcgccc aagcaaccgg
      661 actgaccccc acgcaggtgg gcaactggtt caaaaaccgc agacaaagag accgggcagc
      721 tgcagccaag aacagactcc agcaacaggt tctgtcgcag ggccccgggc gggtgctacg
      781 ctcggagggt gagggcacgc cagaggtgct gggcgtcgcc tccagtcctg ctgccagtct
      841 gtccagcaag gcggccactt cggccatctc catcacatcc agcgacagcg agtgcgacat
      901 ctgacctgtt cactcatcac acttagaaac agaatccagt gtaaaaatca gatgcacaaa
      961 ataagagagg accggaccag caaatacgac gctggccccg tggccaggga ccggcgggcc
     1021 taaactgctc ttgtagggag tttctatcgc aactctgggg cgtgcggtga ggcctgaccc
     1081 aatgccattt ctcttcacgt tgcttttcct ggaggatctg gctgcaaaga ctcatttgga
     1141 acagaactgc acgctgagcg cctgcccttg agtctcctgt gggtatttca tttgtcgaaa
     1201 ggacggtgtt atatatatat atgtatgtat aacttttcct ttgaaggttt ctttttaaaa
     1261 aaaacaaaac aaaacatata tatgctgttt atttacttat ttaaaagact tccatgatag
     1321 gtttctctgt agcttgggga acttgctgtt ctaaatgagc gagctcatgc attctgtgtg
     1381 aagaagccaa ataataaaac accttggtga gtaacctttc ttaatgaagg gagctgctat
     1441 ctcagatttt aaaaaatcac tcgtattccc tttaccgggc atgcaggatg gaatcctgtc
     1501 caaatagtct ctctgacttc tctatttcct ttgatatctc agtatctatt tttaaacaac
     1561 cacggataaa ccgctaacca ctggccacat cggattgtat aaaagtgtag catatgtata
     1621 cacaaacata tgcacattgt cattgtccca gaatttggag catagatacg ccgtcccgcc
     1681 gtccacgcca gcgctttaca ttccgcacac gggtgatcat ggtttgccca cctcatcatt
     1741 tttattaagt gttagtgatt ttcaagaaca attcgagaag acaaattcta gactcaggca
     1801 atgaatccta ttttacaaaa aaaatgcaaa gacgtgcgtg agaattttat gataaaaaag
     1861 tgtttccatt ttgtttgagg ccctcgccca ctcagaagaa gtgtgtgcgc actcatgatc
     1921 gtagggcgag catatagagc atgtagaatt ttactaatgc atgcagtttt tatcaagacc
     1981 attaaaaaag atcggagagc ttgtcagtaa ctagactagc atcttcctgc ttcagacatg
     2041 ggttttagtc aagtaaatta tttttaccaa gagaaatcag tatacaggtt atatattgac
     2101 cagaaagcaa gctacagaga aatgacaggc attttctaaa tcaatgctct ctacatttaa
     2161 catgcaaaca attcatcagg aacttcattg ccttgggagt aaccttagtt aaaatataaa
     2221 atattgttag catgtaactg ttctttttac atacacaggt atataccaca tgcacgtgca
     2281 ggcgtacaca cacacacaca cacacacaca cacactacca tttttgcact aagaaagtaa
     2341 ataatattca gataatctaa gattttgctt tctctagtaa aatggattgc acattacaaa
     2401 atttgacatt gatctttaaa tcacttgagc tggacttctc acccagttag agttctttta
     2461 attcacctct ctgtcctaaa aggtattcca caggtcaaac aaacacctgc taatgtttct
     2521 gaaggcaaaa aaggttaaag taccaaacaa atgaaaaatg aagttacaaa agacaataga
     2581 tagtcaagtg actattggaa gccagggatg tgagaaaagg ctaatgtatg tacgcatgta
     2641 tgtttatgta tgtatgtttg tatgtatgtg tgtttgtatg aatgtatgca tacatgcatg
     2701 catgtttgta tgtcacttaa gcagagctgg cttctgtggg ctttaaaatt atcatcactg
     2761 tccaaatgtt ccttatctag aaaatctttg caaattgaaa ctgtcatagc aaaagagcag
     2821 tagatggaca agtttaggga gcatttgtga ttgaataggt aattctcaaa ttgaaccaac
     2881 gcactacagt ggtccatgct acctctgctg atttctaaag tccctggtag tactttgatt
     2941 gccaaggagc agtctggggc accagaggag agtgcaaatg ctaagaaaat attccttttc
     3001 ctggtcctga gagtgacaac ccatagcgac ctgaaactga gtagctcctt aattttgtac
     3061 ccttggttag tggtggtatt gtgactctaa ctggcagacc tcgggaggtt taggatcagt
     3121 ctggcctaca aggtgagctc caggctagcc atgtctacac ggtgaggttt ttgtttttaa
     3181 cacagagtgt ttcagaaaac accaacatat ttcacccgag gttctctcac ctcaccctag
     3241 tctagaatca gcctagcagg attgcgcttc aatgggaaat tcctggctct caatcttaca
     3301 gtccagctct gtctcctctc atttcagtta tagatgatcc agaaccagta attggagagg
     3361 ctcactggca aatttcattt cttatttttt gtgatcccag gtcaagtaga aaagaaggaa
     3421 agaactaatt agtaaactga tgtacaagaa tttgagatta taaaaatcct aacctactcg
     3481 ccatattcga atgactgaaa cagaaggaaa catctactct ctccggaaat agagcaagcc
     3541 tcagaaacta agctttctct gtatggaaca acgtttaatg gcccttacgg aaaatgtttc
     3601 cctatctgca ttggtgaagg cttttaaata tattatttac ctaaattaac aagctgccca
     3661 agaattacat ttaaagtagt tataatgctt caaaaacatg cagatttatt aatctgattt
     3721 catgttgaaa tcttggggca ccaacattgt tcgaaagata tttttgaatg tgtaccggaa
     3781 atctggtgtc acgtaattgc tctgtgatta attcttggaa tgaccccagg ttggaaatta
     3841 ggccagacct tcaaacatct acttatctaa tcacctgaat cagcccataa acacgtatta
     3901 tgaaaatttt cttttttaaa aaaaatcaat tttatcctag cctaagctgc gttaaaaatc
     3961 gaggcagtag aaaggctcca ataaaggttc tgaatcgag
//
