LOCUS       XM_039078667            2194 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus sirtuin 6 (Sirt6), transcript variant
            X2, mRNA.
ACCESSION   XM_039078667
VERSION     XM_039078667.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039078667.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2194
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2194
                     /gene="Sirt6"
                     /note="sirtuin 6; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 22 ESTs, 3 long SRA
                     reads, 3 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 118
                     samples with support for all annotated introns"
                     /db_xref="GeneID:299638"
                     /db_xref="RGD:1305216"
     CDS             648..1592
                     /gene="Sirt6"
                     /codon_start=1
                     /product="NAD-dependent protein deacylase sirtuin-6
                     isoform X2"
                     /protein_id="XP_038934595.1"
                     /db_xref="GeneID:299638"
                     /db_xref="RGD:1305216"
                     /translation="MCKARRIFDPPEELECKVWELARLMWQSSTVVFHTGAGISTASG
                     IPDFRGPHGVWTMEERGLAPKFDITFENARPSKTHMALVQLERMGFLSFLVSQNVDGL
                     HVRSGFPRDKLAELHGNMFVEECPKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRA
                     CRGELRDTILDWEDALPDRDLTLADEASRTADLSVTLGTSLQIRPSGNLPLATKRRGG
                     RLVIVNLQPTKHDRQADLCIHGYVDEVMCKLMKHLGLEIPTWDGPRVLEKALPPLPRP
                     VAPKAEPPVHLNGSYKPKPDSPVPHRPPKRVKTEAAAS"
ORIGIN      
        1 ggaacagcac gaagcataga gtctagacaa tgggagggac ttgggggcgg gaagtgacgc
       61 cccctgctca acccgggtga ccgggaggaa cctgggtcaa gggagtgagg ggttaataga
      121 aacgagaccc aatcgtcaag ccagggagtg ggcgttttaa tacattaagg gtggtgggga
      181 agcgaccagg tgggcttgtc tgggagaacc tggagcagtg ggaaggtcta cagaactgga
      241 agccggcacc ctcacctggg gtacccctgt accccaccct gtactcctcc ctgtactcct
      301 ccctgagtcc gggccatatg gtccttgaga gtgaggctgt cagtctttgt tgtttctgag
      361 ggggtatagt ggagtggagg gggagtctct ctttgagccc aggttggcct caaactctca
      421 aatcttccaa gtatggtgtt aaaggcctgc cccaccatgc ctgcctgtct catgttatgg
      481 attccctaaa catatcgagt tgcatcttga tttaggggag agagacggat tatctaaagt
      541 ccaggatgag ggatgatgtc accgggaagg tcgtgtgagc cccaacctga gcaaggcaaa
      601 ggagagtggg tgcctgctgg aacagcactc tgggaagagg gctcagcatg tgcaaagcac
      661 gtaggatatt cgacccacca gaggagctgg aatgcaaggt gtgggagctg gcgcggctga
      721 tgtggcagtc ctccactgtg gttttccaca ccggcgcagg catcagcacc gcctccggca
      781 tccccgactt caggggcccc catggcgtgt ggaccatgga ggaacgaggc ctcgccccca
      841 agtttgacat cacctttgag aatgcccggc cctcgaagac ccacatggcc cttgttcagc
      901 tggaacgcat gggcttcctc agcttcctgg tcagccagaa tgtagacggg ctacatgtgc
      961 gctcgggctt ccccagggac aagctggccg agctgcacgg aaacatgttt gtagaggagt
     1021 gccccaagtg taagacgcag tacgtgagag acacggtcgt gggtaccatg ggcctcaagg
     1081 ccactggccg gctctgcacc gtggccaagg cgaggggact tcgggcctgt agaggggagc
     1141 tgagagacac cattctggac tgggaggatg cgttgcctga ccgggaccta acgctcgctg
     1201 atgaggccag caggactgca gacctgtctg tcaccctggg tacctcactg cagatccgcc
     1261 ccagcgggaa cctgcccctt gccactaagc gccgcggagg ccgtctggtc attgtcaacc
     1321 tgcaacccac aaaacatgac cgccaggctg atctgtgcat ccatggctac gtggatgagg
     1381 tgatgtgcaa gctcatgaag cacctggggc tggagatccc cacctgggat ggaccccgag
     1441 tgctagagaa agccctgcca ccgctgccgc gcccagtagc acccaaggct gagccccctg
     1501 tgcatctcaa tggttcctat aagcccaagc ccgacagccc tgtaccccac aggcctccca
     1561 aaagagtgaa gacagaggct gccgccagct gacccgagtg tgtggggcgg gactggtgct
     1621 tgaagaaacc acacatgttg ggggttcttt gttttttata tcctggggac taaacccagg
     1681 tttgcatatc ccacaccccg gcctcttttc agattttcct ttgagaccag ggttccctaa
     1741 atctctcagg ctggcctgga actcactact gtagcccagg ctggcctgga gctagccctg
     1801 cccacctcag cctccactgt agcagggatg gcgggcagac acccagtgtt cagcacagtt
     1861 ccttccgagt ctcactgtgt cccttgtccg ggtccttctg aggaatctca gggcaagggg
     1921 agtcccacgc atgaggaaga ggctgtgccc tgaggatgca cgtgcctctc caccaatcac
     1981 accccactca ccactcagga tgtgcctgga gcggcagcta cacactccac acaccactgc
     2041 tgccccctgc actcacccct ggccctgaca cagagccacc aaggacccat ctatgcatag
     2101 gagagacaag ggcccaccag gcacccatct gtgctaaggg ccccaggctt ccagaagctc
     2161 ccaatgcaat aaaaaaattc atttcattca ttta
//
