LOCUS       XM_006234952            3800 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus signal-regulatory protein alpha
            (Sirpa), transcript variant X3, mRNA.
ACCESSION   XM_006234952
VERSION     XM_006234952.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006234952.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006234952.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3800
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3800
                     /gene="Sirpa"
                     /gene_synonym="Bit; Ptpns1; SHPS-1"
                     /note="signal-regulatory protein alpha; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 39 ESTs, 11 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 181 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:25528"
                     /db_xref="RGD:3449"
     CDS             166..1707
                     /gene="Sirpa"
                     /gene_synonym="Bit; Ptpns1; SHPS-1"
                     /codon_start=1
                     /product="tyrosine-protein phosphatase non-receptor type
                     substrate 1 isoform X1"
                     /protein_id="XP_006235014.1"
                     /db_xref="GeneID:25528"
                     /db_xref="RGD:3449"
                     /translation="MEPAGPAPGRLGPLLFCLLLSASCFCAGASGKELKVTQADKSVS
                     VAAGDSATLNCTVSSLTPVGPIKWFKGEGQNRSPIYSFIGGEHFPRITNVSDATKRNN
                     MDFSICISNVTPEDAGTYYCVKFQKGIVEPDTEIKSGGGTTLYVLAKPSSPEVSGPDS
                     RGSPGQTVNFTCKSYGFSPRNITLKWLKDGKELSHLETTISSKSNVSYNISSTVSVKL
                     SPEDIHSRVICEVAHVTLEGRPLNGTANFSNIIRVSPTLKITQQPLTPASQVNLTCQV
                     QKFYPKALQLNWLENGNLSRTDKPEHFTDNRDGTYNYTSLFLVNSSAHREDVVFTCQV
                     EHDSQPAITENHTVRAFAHSSSGGSMETIPDNNAYYNWNVFIGVGVACALLVVLLMAA
                     LYLLRIKQKKAKGSTSSTRLHEPEKNAREITQVQSLIQDTNDINDITYADLNLPKEKK
                     PAPRVPEPNNHTEYASIETGKLPRPEDTLTYADLDMVHLNRAQPTPKPEPSFSEYASV
                     QVQRK"
ORIGIN      
        1 tgcccacgcg gaggccgacc ttcggctttg ggacacacgg tcagggcctc ttggggaggg
       61 gcagaaggca aacctccccg ccccctccac tctccaccct tgccagcgcg cctgccgccg
      121 gcagcctctt gcccactgga gactagaact gacccgccgc ggcccatgga gcccgccggc
      181 ccggcccctg gccgcctagg gccgctgctg ttctgcctgc tgctctccgc gtcctgtttc
      241 tgtgcaggag ccagcgggaa agaactgaag gtgactcagg ctgacaaatc agtgtctgtt
      301 gctgctggag attcggccac tctgaactgc actgtgtcct ccctgacgcc tgtgggaccc
      361 attaagtggt tcaaaggaga agggcaaaat cggagcccga tctacagttt cataggagga
      421 gaacactttc ctcgaattac aaatgtttca gatgctacta agagaaacaa tatggacttt
      481 agcatctgta tcagtaatgt caccccagaa gatgctggca cctactactg tgtgaagttc
      541 cagaaaggaa tagtagagcc tgacacagaa attaaatctg gagggggaac aacgctctat
      601 gtactcgcca aaccttcttc accggaagta tcgggcccag actccagggg ctctcctgga
      661 cagacagtga acttcacctg caagtcttac ggcttctctc cccggaatat caccctgaag
      721 tggctcaaag atgggaaaga actctcccat ttggagacca ccatctccag taaaagcaat
      781 gtctcctaca acatctccag cacagtcagc gtgaaactaa gccccgagga cattcattct
      841 cgggtcatct gcgaggtagc ccacgtcacc ttggaaggac gcccgcttaa tgggaccgct
      901 aacttttcta acatcatccg agtttcaccc accttgaaga tcacccaaca gcccctgacg
      961 cccgcgagcc aggtgaacct cacctgccag gtgcagaagt tctaccccaa ggctctccag
     1021 ctgaactggc tggagaatgg aaacttatca cggacggaca agcccgagca tttcacagac
     1081 aacagggatg ggacctataa ttacacaagc ctgttcctgg tgaactcatc tgctcacaga
     1141 gaggatgtgg tattcacgtg ccaggtggag catgacagtc agccagcgat caccgaaaac
     1201 cataccgtgc gggcatttgc ccactcgagt agtggaggca gcatggaaac catccctgat
     1261 aataatgctt actacaactg gaacgtcttc atcggtgtgg gtgtggcgtg tgctttgcta
     1321 gtagtcctgc tgatggctgc cctctacctc ctccgaatca aacagaagaa agccaagggc
     1381 tcaacttctt ccacacggtt gcacgagccc gagaagaatg ccagggaaat aacccaggta
     1441 cagtctttga tccaggacac aaatgacatc aacgacatca catacgcaga cctgaatctg
     1501 cccaaagaga agaagcccgc cccccgggtc cccgagccca acaaccacac agaatatgca
     1561 agcattgaga caggcaaact gcctaggcca gaggataccc tcacctatgc tgacctggac
     1621 atggtccacc tcaaccgggc acagccaacc cccaagcctg agccatcctt ctcagagtat
     1681 gccagtgtcc aagtccagag gaagtgaatg gggctgtggt tggctctagg ccccatcccc
     1741 acaagttttc ttgtcctaca tggagtggcc atgatgagga caaccagcca gccagccctg
     1801 tctccagaag gccaggtggc acaggtccta ggaccagggg taagggtggc ttctgtcttc
     1861 cctccgtggc tctccaacac ctcttggaca cccatgtccc cttcttctgg agctgggtgt
     1921 tgcagaacca gagggggaac tggagaaagc tgcctagaat ccaagaagcg ttgtgcctca
     1981 gcccatcaca ctgggtctgg atcctggtct tggcaacccc caggttgctt ccttgatgct
     2041 ccagcgcctg gtcttctgtg tggagaagag ttcaccatct ccatccaact tgagcttcgg
     2101 ggccagactc cctttagatc agaccgcccc atgtgtggaa gaactacacc aggagtcaac
     2161 aagttttcag ccaacagtgc tagcctcccc acctcccagg ctgacgagcc ctgaggagaa
     2221 ggaaccctct tcccctagac cagcagagac tccctgggca tgttcagtgt ggccccaccc
     2281 ttccagtccc agctcgcttc ctccagctag cactaactca acagcattgc tctgtggacg
     2341 cctgtaaatt attgagaaat gtgaactgtg cagtcttgaa gctaaggtgt tagaaaattt
     2401 gatttgtgct gtttagttgt tgttgggttt cttttctttt cttttttttt cttccttttt
     2461 ctttcttctt tttttctttt cccccttaaa acaacagcag cagcatcttg gctctttgtc
     2521 atgtgttgaa tggttgggtc ttgtgaagtc tgaggtctaa cagtttattg tcccggaagg
     2581 attttcttat agcagaaaca gatttttttt ccaattccca gcaccctgag gaccaagaag
     2641 gatccctctg ttgtcatttt cagcactcag cgtcactggg atgagccagg ctctgtcccc
     2701 acagctggcc cttggcctcc atggctactg tggtaagtgc agccttgtct aatccagtgc
     2761 tgacgttggc cattcctcat tgaggagaga aggtcagtga caaactcaca agcactgcag
     2821 aggcatacgg agagaaggga cgctcggcca gcacccggta ttccagcgct ctgaggtaat
     2881 cagtgcaagg agtctgttat taccatcaga cctcagcagg atcatactgg aacagaacct
     2941 gatcatacct gtgacaacac agctgtgagc cagggcaaac caccccactg tcccagagtc
     3001 tgggcagagg ctctgacccc cacccttcaa actggatgtc ggggcctggc tgggcccaat
     3061 ggcaagcaga tgttgcaacc ctagctatct ggtcttaaca tgcagctcag taagttgagg
     3121 cgctaatgtc cccccatgcc gggggattcc tggttccggc tcttcaagta agaagctgat
     3181 tcaacctgcc tgtttctgta ggtgtgacag ggatgtcagg aaaacagcca ggactcatct
     3241 ctatagggct ggtgacctga tacttcccat aaaggcatcc aggagttagc tgacccaata
     3301 gtcagagttg acctcactgg cctagcaaac cgtaacttgt ctttggccca gccatggtct
     3361 tgggctgtct tctaattcca aagggttggt aggtaaagat ccatcctctt cccctctgcc
     3421 aagagacatc acgtgtgtac acacacacat gcgcgcgcgc acacacacac acacacacac
     3481 acacacacac acacacacgg gtgtataggt gagttaaaag gatgtcctcg ctgacatcct
     3541 aattttgtct taagtttttt tggagggaga aaggaaagag gcagggaaga tacgtagctc
     3601 tagctttagt caggcagcct ggggggatcc ccaagcctat gtatggaacc ctggtacgaa
     3661 agcgccctgt gaggagtggg atttcagttt tatctgtaga ccagatgaga aggagaaagg
     3721 ccccattttg tacatagttg caacttaaaa tttttggctt gcaaaatatt tttgtaataa
     3781 agatttctgg gtaacaatga
//
