LOCUS       XM_008772025            1852 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus SIL1 nucleotide exchange factor
            (Sil1), transcript variant X4, mRNA.
ACCESSION   XM_008772025
VERSION     XM_008772025.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008772025.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008772025.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1852
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1852
                     /gene="Sil1"
                     /note="SIL1 nucleotide exchange factor; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 20 ESTs, 2 long SRA reads, 5 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 40 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:291673"
                     /db_xref="RGD:735103"
     CDS             303..1700
                     /gene="Sil1"
                     /codon_start=1
                     /product="nucleotide exchange factor SIL1 isoform X2"
                     /protein_id="XP_008770247.1"
                     /db_xref="GeneID:291673"
                     /db_xref="RGD:735103"
                     /translation="MAPQHLPSTRMAPQGMLLGLLLASCLTFCLSCQNSNNFALTNPE
                     KSTHEDSDTKETRREEELDAEVLEVLNPTQEWQALQPGQAVPAGSHVRMNLQTGVNEV
                     KLQQEDKFQSNWKGFKRGRRLDINTNTYTSQDLKSALAKFKEGTEMENSKDELARQAT
                     VKQLFRPIEELKKEFDELNVVLETDMQIMVRLINKFNSSSSSLEEKVAALFDLEYYVH
                     QMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQK
                     LLVILATEQPLPAKKKVLFALCSLLRHFPYAQQQFLKLGGLQVLRSLVQEKSAKVLAV
                     RVVTLLYDLVTEKMFAEEEAELTQESSPEKLQQYRQVQLLPGLREQGWCEITAQLLAL
                     PEHDAREKVLQTLGALLATCRDRYRQDLELSRTLGSLQAEYQALASLELQEGEDDGYF
                     RELLASIDSLVKELR"
ORIGIN      
        1 tgacgtaata ggcacgcgcc ttcagattca ggcagccact ggcacggcgt ttgcgcagga
       61 ggagttggtt gccgctgcag ccgcctggaa ttgtggggat tgtgtctgcc cctaggctgc
      121 ggtggaaagc cgaagaatgt ttgttggcca tgttctgttc tgtggagacc agcaaagctg
      181 taaagagaac ccacttcatt aagagactct agaagaaaac ctgagcaact cttggtgctt
      241 ccccagggat atgcatcttt cctcctccat accatgccaa agttgggccc caggtcctgg
      301 ttatggctcc tcagcacctg ccttcaacta ggatggcccc tcaaggaatg ctgctggggc
      361 tgctgttggc ttcctgttta actttctgcc tcagttgtca gaactcaaat aattttgcac
      421 tcaccaaccc agagaagagt acccacgagg actcagatac aaaggaaacc agaagagagg
      481 aggagctgga tgccgaagtc ctagaggtgt taaacccaac ccaagagtgg caggctcttc
      541 aaccaggaca ggctgttcct gcaggatccc atgtgcgaat gaacctacag actggagtaa
      601 acgaggtgaa actccaacaa gaagacaaat tccaaagtaa ttggaaagga tttaaaagag
      661 gcagaaggct ggacatcaat accaacacct acacgtctca ggacctcaag agtgcactgg
      721 ccaagttcaa ggaggggaca gagatggaga attcaaagga tgaactggca agacaggcca
      781 cggtaaagca gctcttccgc cccatcgagg agctgaagaa ggaatttgat gagctgaatg
      841 ttgttcttga gactgacatg cagattatgg ttcggctgat aaacaagttc aacagctcca
      901 gctctagcct ggaagagaag gttgctgcac tctttgatct tgagtactat gtccatcaga
      961 tggataacgc acaggacctg ctgtcctttg gtggccttca agtggtgatt aatgggctca
     1021 acagcacaga acccctggtg aaggagtatg ctgcttttgt gctgggggcc gccttttcca
     1081 gcaatccaaa ggtccaggtg gaagccattg aaggaggagc tctgcagaag ctgctggtca
     1141 tcctggccac agagcagcct ctccccgcca agaagaaggt cctgtttgca ctgtgctctt
     1201 tacttcgcca cttcccctac gcccagcagc agttcctgaa gctcgggggg ctgcaggtcc
     1261 tcaggagcct ggtgcaggag aagagtgcga aggtactggc cgtgcgagtg gtcaccttgc
     1321 tctatgacct ggtcaccgag aagatgtttg ctgaggagga ggctgagctg acccaggagt
     1381 cctccccaga gaagctgcag cagtaccggc aggtgcagct cctgcccggc ctgcgggaac
     1441 agggctggtg tgagatcacg gcccagctcc tggcccttcc agagcacgac gctcgggaga
     1501 aggtgctgca gacgctgggc gccctcctcg ccacctgccg ggaccgctac cgtcaagacc
     1561 tggagctgag ccggacactg ggcagtctcc aggcagagta ccaagccctg gcctccctgg
     1621 agctccaaga aggtgaagat gacggctact tccgggaact gctggcctcc atcgacagct
     1681 tggtgaagga gctaagatga ggctgccacg ctgagacagg actggatgga tgctgctagt
     1741 gagagctctg gtgggctctt caggggacag cagccaggag gaggacttcc ctactggggc
     1801 atgagctttt tctgggcaga gctggctggg tcattaaaca gagacatgta ga
//
