LOCUS       NM_001012182            2393 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus suppressor of IKBKE 1 (Sike1), mRNA.
ACCESSION   NM_001012182 XM_342305
VERSION     NM_001012182.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2393)
  AUTHORS   Lant,B., Yu,B., Goudreault,M., Holmyard,D., Knight,J.D., Xu,P.,
            Zhao,L., Chin,K., Wallace,E., Zhen,M., Gingras,A.C. and Derry,W.B.
  TITLE     CCM-3/STRIPAK promotes seamless tube extension through endocytic
            recycling
  JOURNAL   Nat Commun 6, 6449 (2015)
   PUBMED   25743393
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC089208.1 and BI301124.1.
            
            On Oct 11, 2007 this sequence version replaced NM_001012182.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089208.1, EV775549.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2361              BC089208.1         1-2361
            2362-2393           BI301124.1         1-32                c
FEATURES             Location/Qualifiers
     source          1..2393
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2393
                     /gene="Sike1"
                     /gene_synonym="RGD1311316; Sike"
                     /note="suppressor of IKBKE 1"
                     /db_xref="GeneID:362007"
                     /db_xref="RGD:1311316"
     exon            1..250
                     /gene="Sike1"
                     /gene_synonym="RGD1311316; Sike"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..715
                     /gene="Sike1"
                     /gene_synonym="RGD1311316; Sike"
                     /note="suppressor of IKK-epsilon"
                     /codon_start=1
                     /product="suppressor of IKBKE 1"
                     /protein_id="NP_001012182.1"
                     /db_xref="GeneID:362007"
                     /db_xref="RGD:1311316"
                     /translation="MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMR
                     EAGAVLPEQYQEDASDVKDMSKYKPHILLSQENTQIRDLQQENRELWVSLEEHQDALE
                     LIMSKYRKQMLQLMVAKQAVDAEPVLKAHQSHSAEIESQIDRICEMGAVMRRAVQVDD
                     NQFCKIQEKLAQLELENKELRELLSISSESLQVGKESSVAPEAQTIR"
     exon            251..356
                     /gene="Sike1"
                     /gene_synonym="RGD1311316; Sike"
                     /inference="alignment:Splign:2.1.0"
     exon            357..499
                     /gene="Sike1"
                     /gene_synonym="RGD1311316; Sike"
                     /inference="alignment:Splign:2.1.0"
     exon            500..613
                     /gene="Sike1"
                     /gene_synonym="RGD1311316; Sike"
                     /inference="alignment:Splign:2.1.0"
     exon            614..2376
                     /gene="Sike1"
                     /gene_synonym="RGD1311316; Sike"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggaagtgac gcgggtcgca ctgagccggg gctggggaag ggctgagcga atcgccgagg
       61 ctagcgggcc gggcgcgcct cttcggccac tatgagctgt acgatcgaga agatcttgac
      121 ggacgccaag acgctgctgg agcggctgcg cgaacacgat gcggcggccg agtcgctggt
      181 ggaccagtcg gccgcgctgc accggcgggt ggctgcgatg cgggaggcgg gcgccgtgtt
      241 gccggagcag tatcaagagg atgcatccga cgtgaaggac atgtctaaat ataaacctca
      301 cattctgctg tctcaagaga atactcagat tagagactta cagcaggaaa acagagagct
      361 gtgggtctcc ttggaggagc accaggatgc attggaactc atcatgagca agtaccggaa
      421 acaaatgtta cagttaatgg ttgctaaaca agcagtggat gctgaaccag ttttgaaagc
      481 tcatcagtct cactctgcag aaattgaaag tcagatcgat agaatctgtg aaatgggagc
      541 agtgatgcgg agagcggttc aggtggacga taaccagttc tgtaagattc aggagaaact
      601 agctcaactg gagcttgaaa ataaggaact tcgagaatta ctgtccatca gcagtgagtc
      661 tctccaggtt ggaaaagaaa gctctgtggc tcccgaggct cagaccatca ggtaactgga
      721 cttctaagcg ctggctgcag ccggctgccc gtcatggaga gaagcagtta cctctgctct
      781 cagaagtgtc cgtccaagag tcttgccaca gactgattta gtgttgattg gaggtatggg
      841 gtggcagttt agaattgcca cttgatattc attgtccact aaagagtttg gggtgtgtta
      901 gtaaaactag acaagtctcc cattgctgtg acagagacca tgtgtgtcac tctgggaccg
      961 gaatctataa actgtggtct gcaatttgat gttgtttttt cacagcttgg aaacgctgaa
     1021 cacttttatt ataaaccatg gttttatttt atataggaat ataagaatcc cttctaagaa
     1081 tttttaaaag atttaacttt ttaaaaatac atatttggtg tcaacctgga aatttttttt
     1141 ttcttccact tataaaagta agatgatttc acagaaacga ttggcagatt ctctgagtga
     1201 catcactcat ctgtggggtt ttgatcctct ccggtgctag gagtcggcac tttgtggtca
     1261 ggtgtctttg ctcttaattt gagagaatct attactagtc cccaggaaat atgcttgaaa
     1321 acaaggaaac tgggttaggc ttgttcctcc tcctcccctc aaggatccac agtccttgag
     1381 agagtgctga ggaacttgga cctgccctgt catgtacagg gagctattaa atgtccgtga
     1441 ctgtacatgt acatttgact taaatgccaa aagtagctct cagctatctg agtagtagtc
     1501 agttttccat tatgtctgcc tggggaatct tcagcttagg tagttgcctc gtatgaagaa
     1561 catgtatata tctcacaggt ttcccacctc ctggctccta ggcactttaa ttgacaccta
     1621 gctgtgcctc acagagcacc atcgcccaga tggtttatac tggcagcagt gcttggctgt
     1681 ctttacacct actgggtttt cacatggaag cattcttatt actcacagaa agttaccaca
     1741 ttcctaaggc cctgcaggca atcaagaaca atcctgaggt cctaatagct ctccgccaac
     1801 tccttcccgt cttagtttac tcatatttca gatttataaa taaccccttt tatactgttt
     1861 gcccagatgg actttgattt tcatttacca tgttaacttt cactccagct gctcccctag
     1921 aagtatcccc taagtgcccc aagtgtactc cacaagccca ttcaggagtg ggtgccctct
     1981 cccacttgtc agctgtccaa acatgtctcg tcgacagcga cagtgacagc attattagac
     2041 agtctatttc agcagtgagc acagagtccc tgtatctgcc ttgtgttccc ttagcactcg
     2101 ctgcaaagtt ctttacatcc agcttccaga agaacccctt catttcagtc ctgagggcag
     2161 agcaggcttt cggtgccctg tgtcatgaac tctgcctggt attgatgctg tgaaggtata
     2221 cagagctagc acactgagtg gagaaagagt gttttacact ttgtgtgaag atgttaatat
     2281 ctcttgcagt ggatggacgc gtttagtgta taaaatgtta gtatgaaatt atctttacta
     2341 ataaaaatct ctttttgaga aggtttgcta attttaaaaa aaaaaaaaaa aaa
//
