LOCUS       XM_056985177            3176 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus sialic acid binding Ig-like lectin 8
            (Siglec8), transcript variant X1, mRNA.
ACCESSION   XM_056985177
VERSION     XM_056985177.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_056985177.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3176
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3176
                     /gene="Siglec8"
                     /note="sialic acid binding Ig-like lectin 8; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 ESTs, 6 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 106
                     samples with support for all annotated introns"
                     /db_xref="GeneID:292846"
                     /db_xref="RGD:1563073"
     CDS             145..1518
                     /gene="Siglec8"
                     /codon_start=1
                     /product="sialic acid-binding Ig-like lectin 12 isoform
                     X1"
                     /protein_id="XP_056841157.1"
                     /db_xref="GeneID:292846"
                     /db_xref="RGD:1563073"
                     /translation="MLLLLLLLWGIKGVEGGAVALKGYTLNVERKVVVQEGLCVLVPC
                     NFSYPKFWQTDSSPVYGYWFRKKANTDIDAPVATNNPKRPAQERTQHRFFLPGDQQKN
                     DCSLNIREIKKKDAGTYFFRLERGKTKYNYLWNMMTLDVTALTNTLRILPETLEAGHP
                     SNLTCSVPWDCEKRAPPVFSWNGTSVSPLSTNTTGSSVLTIIPQPQDHGTNLTCQVTL
                     PGTDVTTRMTIRLNVSYAPKNLTVTVYQGADSVSTILKNGSSLQISEGQSLRLICSAD
                     SYPPANLSWSWGNLTLCPPKLSKPGLLELFPMHLKHEGVYTCQAQHALGSQYISLNLS
                     PQRSATLSEMMMGTLMDSGVTALLFLSFCIILLAVRSCRRKPARTAVVAPHPNALKVS
                     VSQSPLVESHADDSSEPLPSTVEAAPSSTKEEIHYASLSFHEMKPRNSWGQQGSTTEY
                     SEIRLHK"
ORIGIN      
        1 tcctcacagt gcctgggtct gaagctcctc ctcctggggc agccactatc ctggccctca
       61 ccgctgcttc cgctggggct tcctccaagc cttgcatctc ttagttcctc aaagcagagc
      121 ctggagagac attttcagct ggacatgctg ctgttgctgc tgctactctg ggggataaag
      181 ggagtggagg gtggagccgt tgccttgaag ggctacaccc tgaatgtgga aaggaaggtg
      241 gtggtacagg agggcctgtg tgtccttgtg ccctgcaact tctcctatcc caagttctgg
      301 cagactgact catccccagt ttatggatac tggttccgga aaaaagccaa cacagacatt
      361 gatgcccccg tggccacaaa taacccaaaa aggccagcac aggaaaggac ccagcatcga
      421 ttcttcctgc ctggagacca gcaaaagaac gactgctccc tgaacatcag agagatcaaa
      481 aagaaggatg cagggacata cttctttcgc ctggagagag gaaaaacaaa gtataattat
      541 ctttggaaca tgatgactct ggatgtgaca gctctcacta acaccctccg tattctcccg
      601 gagacacttg aagctggtca tcccagcaac ctgacctgct ctgtgccttg ggactgtgag
      661 aagagggcac cccctgtctt ctcctggaat ggtacctctg tgtcaccctt gagcactaac
      721 accactggtt cctcagtgct aacaatcatc ccccagcccc aggaccatgg caccaacctc
      781 acttgtcagg tgacccttcc tggaactgat gtgaccacaa gaatgaccat tcgtctcaac
      841 gtgtcatatg ctccaaagaa tctgactgtg accgtctatc aaggagctga ctcagtatcc
      901 acaatcctga agaacggctc atctcttcaa atctctgagg gccagtcact ccgtctcatc
      961 tgtagcgccg acagctatcc cccggcaaac ctaagctggt cctggggtaa cctgactctg
     1021 tgtccaccaa agttgtctaa acccggactc ctggagctgt ttccaatgca tcttaagcac
     1081 gaaggagtgt atacctgcca agctcagcac gccctaggct cccaatacat ttccctgaac
     1141 ctgtctccac agagaagtgc aactttatct gaaatgatga tggggaccct tatggattca
     1201 ggtgtcacag ccctcctttt cctgtctttc tgcatcattc tcctggcagt aagatcctgc
     1261 aggaggaaac cagccaggac agctgtggta gctccgcatc caaatgccct caaggtctca
     1321 gtgtctcaga gtcccctggt tgaatcccat gcagatgaca gctctgagcc cctgccttcc
     1381 acagttgagg cagccccctc ctccacaaag gaagagatac attatgcctc cctcagcttt
     1441 catgaaatga agcccaggaa ctcctggggg cagcagggct ctaccacaga gtactcagag
     1501 ataaggctcc acaaatgacc acatggccat gaacattgcc agaaggagca tggcggccac
     1561 aggaggctgg ctctgcagaa gcaaaagggt cgcctaggtt gacatgcgat gtgtaggact
     1621 tcagggccgt tcttttcatg acacaggcgt tctgctactg cccacgccct tgtgctaccc
     1681 tgcccaccca attgctattg tgccctggaa atcataagct tgactttttt ctttctcttc
     1741 ctttccacca ccctctcttg ttatttcaag tcagggtttc ctgggttgaa cttgctctgc
     1801 agaccaagct gctcttgaac tcacagagat ccccctacct cttctttcca agtgctggga
     1861 ttaaagatgt gcaccagcac cacccagcat ttgactttgt aattgtatgt gtgtggatgt
     1921 ttggcctgca tgcgcatccg tgcaccacat gcatgcctcg tgcctgcaga ggctggggga
     1981 ggtcatcagc tactctggaa ttggagttac agagggttgt gagtggccac gtgggtgcta
     2041 ggaaccgaac ccagtcatct gcaagagtat ccagtgctct taaccactaa gccatctctc
     2101 cggtactaag attttttttt ttttttttta gattttactt aaaaattggc atgtattgtt
     2161 tacacagtga tggtttgctg tgttttcttt caagtgtatc acctattttg gccatgctca
     2221 tccccttctc ctgtagttgc cagtctcctc tctctctccc cccaaacaat ccctttactg
     2281 tgtaacgttg tatgtatcgg ttacctttct tggttttgtg gataggacgc ggacagaaac
     2341 atgaaggatg gaaaggttta ttcttgttca tggtttcagt ccatcatggt gaggaaggga
     2401 atatggtggt gctcaagggg gcacatgtag tggaggctcc acatcgtgat ggatcaggaa
     2461 gcagtgggct caagccagaa ccagatgtag atatcatctt ctaagcacgc cccagacacg
     2521 tacttctata aattgggtca catgtccgaa agattccacg gctttagaaa atactgtgac
     2581 cagctgagta ccaagtgtcc aaatatatgg gcctctgtag aaaatataca tttaaaccca
     2641 aactagatgg atgatagttg gatagacaga cagacaggga aaggttagta gatattatag
     2701 atagataata gaaaatagag acatagaaat gagatagaca gacttacagt atagataaaa
     2761 tatacaaggt aagtggtgga tataagacag atggacagat agatgacaga gaaaagatga
     2821 taggcagaca acttgtcaga gacgctgctc cactctgcct tgctttttgg gaagcatgac
     2881 tgagcgcagc tcagagaaag gtgcagacag gggcgctgtg gatgctgggg agctgccaaa
     2941 tgtgtcttaa cttggtttcc tttccctggt ttttaaaaac agtgtatgta ctttgtgagg
     3001 gaaaagtacc ttagaaccaa agcaaaaaga agaacgaaac ataaagagga aacactggta
     3061 atagttaaca ttttttcaat ttttcacttg catgtgaaaa ctggactgaa cctgcatttg
     3121 tgctatacat atcatatcta tcactgttga ctaatctatg cttcttggtt tggtta
//
