LOCUS       NM_001106249            2474 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus sialic acid binding Ig-like lectin 5 (Siglec5),
            mRNA.
ACCESSION   NM_001106249 XM_001080306 XM_218613
VERSION     NM_001106249.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2474)
  AUTHORS   Tateno,H., Li,H., Schur,M.J., Bovin,N., Crocker,P.R.,
            Wakarchuk,W.W. and Paulson,J.C.
  TITLE     Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F
            reflect roles in cell signaling and innate immunity
  JOURNAL   Mol Cell Biol 27 (16), 5699-5710 (2007)
   PUBMED   17562860
REFERENCE   2  (bases 1 to 2474)
  AUTHORS   Zhang,J.Q., Biedermann,B., Nitschke,L. and Crocker,P.R.
  TITLE     The murine inhibitory receptor mSiglec-E is expressed broadly on
            cells of the innate immune system whereas mSiglec-F is restricted
            to eosinophils
  JOURNAL   Eur J Immunol 34 (4), 1175-1184 (2004)
   PUBMED   15048729
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On Jan 12, 2008 this sequence version replaced NM_001106249.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5756307,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2474
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2474
                     /gene="Siglec5"
                     /note="sialic acid binding Ig-like lectin 5"
                     /db_xref="GeneID:292843"
                     /db_xref="RGD:1305432"
     exon            1..117
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1787
                     /gene="Siglec5"
                     /codon_start=1
                     /product="sialic acid-binding Ig-like lectin 5 precursor"
                     /protein_id="NP_001099719.2"
                     /db_xref="GeneID:292843"
                     /db_xref="RGD:1305432"
                     /translation="MLWAQLLPLLWAGSLAVENYELSLTESVTVQEGLCVFVPCQVKY
                     PASGGSVFGYWFQDGANTNLNSPVATNDPHRPVQQETQGRFYLVGGIDTKNCSLDIRD
                     ARKSDTGKYFFRLDGSVKYSFRNRMLSVHVTALTKTPNLQVTSTLVSGTSTRVICSVL
                     WACEQGTPPIFSWMSSALTSLGRRTILSSELNLTPRPQDNGTNLICQVTFPGAGVTVE
                     RTQQLSVTYAPQKLTIRVSWGDGTETKVLQSGASLQIQEGESLRLVCVADSNPSAMLS
                     WKRQTQKNFRLSKGDELQLPRVELEDQGKYICQAKNSLGTQTASVSLSIRSLLQLLAP
                     SCSWDSEGLHCSCSSRAWPAPSLGWRLGEGLLEGNSSNASFTVMSSSAGPWVNSSLSL
                     SVEFSTDHRLSCEAWNDYGVQRATIVLVPGQGVSQDKSETSGGAVQGAIWGAGLMALL
                     AVSFCLIFFIVKFLRKKSALEVAAMEGNHLAKNLVSTINSASMISSNIPLRYPIQDHL
                     NESESQTQKEEPPLATAPDIPKDEPELHYASLSFQGPRPQQPKNTETIKSVYTEIKIH
                     KR"
     exon            118..480
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
     exon            481..759
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
     exon            760..807
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
     exon            808..1059
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1362
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
     exon            1363..1459
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1595
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..2474
                     /gene="Siglec5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagtcctgtg acattgaagc ctatgaccct cgaactgacc aagttttctg tctctggagc
       61 ctaggacctt tcactgcgtg atgctgtggg cacagctgct gcccctgctg tgggcagggt
      121 ccctggccgt ggagaattat gagctctcat tgactgaatc agtgacggtg caggagggtc
      181 tgtgcgtctt tgtaccctgc caagtcaagt accctgcttc cgggggttct gtttttggct
      241 actggttcca ggatggggcc aacacaaacc tcaactctcc agtggctaca aatgacccac
      301 atcgaccagt acagcaggaa actcaaggtc gtttctatct cgtggggggc atagatacta
      361 aaaattgctc cctggacatc agagacgcac ggaaaagtga cacaggaaag tacttcttca
      421 ggttggatgg aagtgtgaaa tacagtttcc ggaatcggat gctctctgtg catgtgacag
      481 ctctgactaa gacccctaac ctccaagtca catctaccct ggtgtctggc acttctaccc
      541 gagtgatctg ttctgtgctc tgggcctgtg agcaggggac accccccatc ttttcctgga
      601 tgtcatctgc cctcacttcc ctgggccgca gaaccatcct ctcctcagag ctgaacctca
      661 cacctaggcc tcaggacaac ggcaccaacc tcatctgtca ggtgaccttc cctggtgctg
      721 gtgttactgt ggagaggact caacagctca gtgtcaccta tgctccacag aagctgacca
      781 tcagggtgtc ctggggagat ggcacagaaa ctaaagtcct gcagagtgga gcatctctgc
      841 agatccaaga gggtgagtcc ctgcgcctgg tctgtgtggc agacagcaac ccctctgcca
      901 tgctgagctg gaagcgccag acccagaaga acttccggct ctctaagggt gatgaacttc
      961 aactgccacg ggtggagttg gaggaccagg gaaaatacat ctgccaggct aagaacagtc
     1021 tgggtactca gacagcctct gtgagcctca gcataaggag ccttctacag ctgctggcac
     1081 cctcctgctc ctgggattct gagggtctgc actgcagctg ctcctccaga gcctggcctg
     1141 ccccgtccct gggctggcgg ctgggggagg ggctgctgga gggaaacagc agcaatgcct
     1201 ccttcacagt tatgtccagc tctgcaggac cgtgggtcaa cagctccctg agcctcagtg
     1261 tggaattcag cactgaccac agactcagct gtgaagcttg gaatgactat ggagttcaga
     1321 gagccactat cgtgctggtt ccaggacaag gagtctcaca ggacaaatca gaaaccagtg
     1381 gaggagcggt tcagggggcc atctggggag ctggtcttat ggctttgctt gctgtctcct
     1441 tctgcctcat cttcttcata gtgaagttcc tcaggaagaa atcagcattg gaagtagcag
     1501 ccatggaagg caaccacctt gccaagaacc ttgtctccac cataaatagt gcaagcatga
     1561 tttcgtccaa cattccattg agatacccca tccaggatca tctgaatgaa tcagagtcac
     1621 agacccagaa agaagagcca cctcttgcca cagccccaga catcccaaag gatgagcccg
     1681 aacttcacta tgcctccctc tccttccaag gtccgaggcc ccagcagcca aagaacacgg
     1741 agaccatcaa gtctgtttac acagagatca agattcacaa gcgctgaagc tccttgcccc
     1801 atgtgtcagt cacagtgctg gctggagtcc cagaaaggca tggctgaaga tagcatgtgt
     1861 taggagcata ttctggcatc agtggccctc ttaaccaaag gatatgtagt ggaaggaggg
     1921 agttttggaa ggagagaagg ttacagagat tcctaggttc aaatccatat tcagtgttat
     1981 tcccagagaa gccacctttt ttctttgtgc cccctcttcc tcctctgtaa agtggagtca
     2041 taatctgagg agtaccaagg agagaatgtg tttattgttg attatattgc tttatgttgc
     2101 ctgagcagtg gggaagaacg ttttgtcttt attgcataac ttgaatttta cttgtatatt
     2161 tttaaagaac atatgttagt tcctaaagtt attctgtttt gaagtgtgac tgtgttgtag
     2221 ctacctgtat ctcagattgg actcattgga cattctgcaa actcttaaag atcatacaga
     2281 tatcagccca gactactata cccagtaaaa ttaacaatca tggggcataa agctaatata
     2341 taaagatctc ccacaaatca ataaaagtga cagacaattc aatacaaaat ggtaatatgt
     2401 gagtggtaag caaacataca gaaaggtgac caatcagtgc ttgtcaacga aatataaata
     2461 aatacagtac acct
//
