LOCUS       NP_001099719             568 aa            linear   ROD 24-JUN-2024
DEFINITION  sialic acid-binding Ig-like lectin 5 precursor [Rattus norvegicus].
ACCESSION   NP_001099719 XP_001080306 XP_218613
VERSION     NP_001099719.2
DBSOURCE    REFSEQ: accession NM_001106249.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 568)
  AUTHORS   Tateno,H., Li,H., Schur,M.J., Bovin,N., Crocker,P.R.,
            Wakarchuk,W.W. and Paulson,J.C.
  TITLE     Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F
            reflect roles in cell signaling and innate immunity
  JOURNAL   Mol Cell Biol 27 (16), 5699-5710 (2007)
   PUBMED   17562860
REFERENCE   2  (residues 1 to 568)
  AUTHORS   Zhang,J.Q., Biedermann,B., Nitschke,L. and Crocker,P.R.
  TITLE     The murine inhibitory receptor mSiglec-E is expressed broadly on
            cells of the innate immune system whereas mSiglec-F is restricted
            to eosinophils
  JOURNAL   Eur J Immunol 34 (4), 1175-1184 (2004)
   PUBMED   15048729
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On Jan 12, 2008 this sequence version replaced NP_001099719.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5756307,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     Protein         1..568
                     /product="sialic acid-binding Ig-like lectin 5 precursor"
                     /calculated_mol_wt=60274
     sig_peptide     1..16
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=1783
     Region          20..133
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          36..40
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          52..56
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          96..100
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          110..115
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          122..128
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          139..223
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          153..157
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          170..174
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          189..193
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          203..208
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          218..221
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          252..325
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          261..265
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          274..281
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          294..298
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          305..310
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          320..323
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          <347..419
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          356..360
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:319310"
     Region          388..392
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:319310"
     Region          401..406
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:319310"
     Region          414..417
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:319310"
     CDS             1..568
                     /gene="Siglec5"
                     /coded_by="NM_001106249.2:81..1787"
                     /db_xref="GeneID:292843"
                     /db_xref="RGD:1305432"
ORIGIN      
        1 mlwaqllpll wagslaveny elsltesvtv qeglcvfvpc qvkypasggs vfgywfqdga
       61 ntnlnspvat ndphrpvqqe tqgrfylvgg idtkncsldi rdarksdtgk yffrldgsvk
      121 ysfrnrmlsv hvtaltktpn lqvtstlvsg tstrvicsvl waceqgtppi fswmssalts
      181 lgrrtilsse lnltprpqdn gtnlicqvtf pgagvtvert qqlsvtyapq kltirvswgd
      241 gtetkvlqsg aslqiqeges lrlvcvadsn psamlswkrq tqknfrlskg delqlprvel
      301 edqgkyicqa knslgtqtas vslsirsllq llapscswds eglhcscssr awpapslgwr
      361 lgegllegns snasftvmss sagpwvnssl slsvefstdh rlsceawndy gvqrativlv
      421 pgqgvsqdks etsggavqga iwgaglmall avsfcliffi vkflrkksal evaamegnhl
      481 aknlvstins asmissnipl rypiqdhlne sesqtqkeep platapdipk depelhyasl
      541 sfqgprpqqp kntetiksvy teikihkr
//
