LOCUS       NM_001191942            2555 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus sialic acid binding Ig-like lectin 15 (Siglec15),
            mRNA.
ACCESSION   NM_001191942 XM_574176
VERSION     NM_001191942.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2555)
  AUTHORS   Ishida-Kitagawa,N., Tanaka,K., Bao,X., Kimura,T., Miura,T.,
            Kitaoka,Y., Hayashi,K., Sato,M., Maruoka,M., Ogawa,T., Miyoshi,J.
            and Takeya,T.
  TITLE     Siglec-15 protein regulates formation of functional osteoclasts in
            concert with DNAX-activating protein of 12 kDa (DAP12)
  JOURNAL   J Biol Chem 287 (21), 17493-17502 (2012)
   PUBMED   22451653
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000018.1.
            
            On Oct 3, 2022 this sequence version replaced NM_001191942.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.56914.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN11044071, SAMN12840118
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               JAXUCZ010000018.1  73796791-73797014   c
            225-284             JAXUCZ010000018.1  73788710-73788769   c
            285-668             JAXUCZ010000018.1  73787951-73788334   c
            669-1040            JAXUCZ010000018.1  73786877-73787248   c
            1041-1071           JAXUCZ010000018.1  73785824-73785854   c
            1072-2555           JAXUCZ010000018.1  73781536-73783019   c
FEATURES             Location/Qualifiers
     source          1..2555
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.3"
     gene            1..2555
                     /gene="Siglec15"
                     /gene_synonym="RGD1565948"
                     /note="sialic acid binding Ig-like lectin 15"
                     /db_xref="GeneID:498888"
                     /db_xref="RGD:1565948"
     exon            1..224
                     /gene="Siglec15"
                     /gene_synonym="RGD1565948"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..1198
                     /gene="Siglec15"
                     /gene_synonym="RGD1565948"
                     /codon_start=1
                     /product="sialic acid-binding Ig-like lectin 15 precursor"
                     /protein_id="NP_001178871.1"
                     /db_xref="GeneID:498888"
                     /db_xref="RGD:1565948"
                     /translation="MEGFLQLLACLACVLQMGSPVKTRRDALGNALNTEELSAPSQRW
                     SMQVPAEVSAEVGDMAVLPCTFTHPHRHYDGPLTAIWRAGEPYAGPQVFRCTAAPGSE
                     LCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSRRYFCRVEFTGDAHDRYESRHGV
                     RLHVTAAPRIVNISVLPGTSHAFRALCTAEGEPPPTLAWSGPALGNSSAAMQGQGRGY
                     QVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPAASTLALLLGALGLKALLL
                     LGLLGARATRRRGDHLAAQDTPPRSQAQESNYENLSQMNPPGYQLPRVCCEELLNHHH
                     PVIHHEK"
     exon            225..284
                     /gene="Siglec15"
                     /gene_synonym="RGD1565948"
                     /inference="alignment:Splign:2.1.0"
     exon            285..668
                     /gene="Siglec15"
                     /gene_synonym="RGD1565948"
                     /inference="alignment:Splign:2.1.0"
     exon            669..1040
                     /gene="Siglec15"
                     /gene_synonym="RGD1565948"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1071
                     /gene="Siglec15"
                     /gene_synonym="RGD1565948"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..2555
                     /gene="Siglec15"
                     /gene_synonym="RGD1565948"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaccgctgg ctacttgact gccgctgcca gttcctccag cttgcttaga gtccaatgga
       61 cctgcagact tggcacagag cacacccacc tgcctttgtc acagcacact aagaaggttt
      121 tctgtggtga cctggctggg tagagggctg ctgggtctgc aggcgtcaga gcatggaggg
      181 gttcctccaa ctgctggcct gcttggcctg tgtgctccag atgggatcac ctgtaaaaac
      241 tcgaagagac gctttgggaa atgctctcaa cacagaggag ctcagtgccc catcgcagcg
      301 ctggtccatg caggtgcccg cggaggtgag cgcggaggtt ggcgacatgg cggtgctgcc
      361 ctgcaccttc acgcaccctc accgccacta cgacgggccg ctgaccgcca tctggcgcgc
      421 gggcgagccg tacgcgggcc ctcaagtgtt ccgctgcacc gcggcgccgg gcagcgagct
      481 gtgccagacg gcgctgagcc tgcacggccg cttccgcctg ctgggcaacc cgcgccgcaa
      541 cgacttgtcc ctgcgcgtcg agcgcctcgc cctggcggac agcagacgct acttctgccg
      601 tgtggagttc accggcgacg cccacgatcg ctatgagagt cgccatgggg tccggctgca
      661 cgtgactgct gcgccccgga tcgtcaacat ctcagtgctg cctggcacct cgcatgcctt
      721 ccgcgcgctc tgcacggccg agggggagcc gccgcctacc ctagcctggt ccggccccgc
      781 cctgggcaac agctcggctg ccatgcaagg ccaaggtcgc ggctaccagg tgaccgccga
      841 attgcccgcg ctgacccgcg atggccgcta cacgtgcacg gcagccaata gccttggtcg
      901 cgccgaggcc agcgtctacc tgttccgctt ccacggcgcc cccgcagcct cgaccctggc
      961 gctcctgctg ggcgctctgg gcctcaaggc gttgctgctg cttggccttc tgggtgctcg
     1021 tgccacacgc cgccgaggag atcacctggc tgcccaggac acccctccac ggtctcaggc
     1081 tcaggagtcc aattacgaaa atttaagcca gatgaatccc ccaggctacc agctgccacg
     1141 agtttgctgt gaggaactcc ttaaccacca tcatccagtc attcaccatg aaaaataaag
     1201 gacagtatca ccaggctaga cctgtacagc tcataattcc ttggcagctg tgggccaggc
     1261 aacatccaag gggaccagga tacctgccca cggtactctg ccagcaatct ggacgtatat
     1321 gcatgcccac acaagtctca gcacgaaact tctggaaaaa ctcctcttgt tttttcttac
     1381 ttcgaactac atagtaaagc agacaggaaa ctagccataa ggtctggagg tccaggctcc
     1441 tgtctgctct gtcatggact tgcagtgcgg accaggacac ttccttgacc tatctggggc
     1501 tcagcttctc cctgaagatc tgaagggacc tcgtcaactc caactctagc taaaacgtgg
     1561 gccattggac gtgctgaatt tgtaggtagg tgtggcactg ctcagctttt tggagaacaa
     1621 aggactccca agaaccacct gaggcgggag ctgtgcaaac tgatagcaat ccttggaacc
     1681 attatagcaa gaagaagccc ggagcccctg cctcctgagc tcacacagac tgttccagcc
     1741 gcctgtgatc atctcagctg acccacactt ccttgaactg ggatccaccg agagaagact
     1801 gaagacccac agtctcaaag cgtctgaaag ctgtgtgtca aaacccggga gacctgaagg
     1861 gcgtctgggt ctaagtggtt aaggcagctg tggctctgac ctctctctgg agtgcacccc
     1921 ctcccaggat gtgaacctcc aggaggactg gcaatgtctc cccacttgcc caagcccagc
     1981 caggctaact tcaagagtgg tgctttccta atttgcactt cagtgtgcat ttgttggtcc
     2041 tgttaaagga cagaggtgca gttgggaccg agtaagccac aagacaggag gctaaggaga
     2101 ccatgttttt ctggggacag tatctttgtg ttgagggcag tcagttttca ggcttcccac
     2161 tctgccaagg gtgctgacag ttcatagtta tttcaggatc cgtcaagaac tgttaaggaa
     2221 gcacagggct tgacgtctgg ccctgcttgc aggtaggagc attagagtgt ctctatgaag
     2281 gacctgtgtc accaaggaaa aatataagga tgtggattag agcgtcattg gtctctggag
     2341 ctgtctttca gagccaagaa aattctacga gctactaatt acacactgtg tggtgttggg
     2401 aattcctttt cagggttatg aaaccgaagg aggcatcatt atcggtcagg acgagctagg
     2461 ctgtcctgca ccaacaagcc ctaaaatcag tgactaaaaa tggtctttat cttgcactct
     2521 atcagtcagg gttctctaga gggacaggat ttatg
//
