LOCUS       NM_001401363            2948 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus sialic acid binding Ig-like lectin 10 (Siglec10),
            mRNA.
ACCESSION   NM_001401363 XM_006228948
VERSION     NM_001401363.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2948)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   2  (bases 1 to 2948)
  AUTHORS   Jellusova,J., Wellmann,U., Amann,K., Winkler,T.H. and Nitschke,L.
  TITLE     CD22 x Siglec-G double-deficient mice have massively increased B1
            cell numbers and develop systemic autoimmunity
  JOURNAL   J Immunol 184 (7), 3618-3627 (2010)
   PUBMED   20200274
REFERENCE   3  (bases 1 to 2948)
  AUTHORS   Chen,G.Y., Tang,J., Zheng,P. and Liu,Y.
  TITLE     CD24 and Siglec-10 selectively repress tissue damage-induced immune
            responses
  JOURNAL   Science 323 (5922), 1722-1725 (2009)
   PUBMED   19264983
REFERENCE   4  (bases 1 to 2948)
  AUTHORS   Kitzig,F., Martinez-Barriocanal,A., Lopez-Botet,M. and Sayos,J.
  TITLE     Cloning of two new splice variants of Siglec-10 and mapping of the
            interaction between Siglec-10 and SHP-1
  JOURNAL   Biochem Biophys Res Commun 296 (2), 355-362 (2002)
   PUBMED   12163025
REFERENCE   5  (bases 1 to 2948)
  AUTHORS   Munday,J., Kerr,S., Ni,J., Cornish,A.L., Zhang,J.Q., Nicoll,G.,
            Floyd,H., Mattei,M.G., Moore,P., Liu,D. and Crocker,P.R.
  TITLE     Identification, characterization and leucocyte expression of
            Siglec-10, a novel human sialic acid-binding receptor
  JOURNAL   Biochem J 355 (Pt 2), 489-497 (2001)
   PUBMED   11284738
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 9, 2022 this sequence version replaced XM_006228948.4.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR26643284.636.1, SRR26360186.207185.1
                                    [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN06680413, SAMN06680416 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-114               JAXUCZ010000001.1  102953918-102954031
            115-209             JAXUCZ010000001.1  102954169-102954263
            210-587             JAXUCZ010000001.1  102954347-102954724
            588-866             JAXUCZ010000001.1  102954854-102955132
            867-914             JAXUCZ010000001.1  102955904-102955951
            915-1178            JAXUCZ010000001.1  102956374-102956637
            1179-1226           JAXUCZ010000001.1  102956840-102956887
            1227-1484           JAXUCZ010000001.1  102956987-102957244
            1485-1769           JAXUCZ010000001.1  102957340-102957624
            1770-1857           JAXUCZ010000001.1  102957888-102957975
            1858-1969           JAXUCZ010000001.1  102958071-102958182
            1970-2948           JAXUCZ010000001.1  102961986-102962964
FEATURES             Location/Qualifiers
     source          1..2948
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2948
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /note="sialic acid binding Ig-like lectin 10"
                     /db_xref="GeneID:292844"
                     /db_xref="RGD:1307441"
     exon            1..114
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            115..209
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     CDS             170..2236
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /note="sialic acid binding Ig-like lectin G"
                     /codon_start=1
                     /product="sialic acid-binding Ig-like lectin 10 precursor"
                     /protein_id="NP_001388292.1"
                     /db_xref="GeneID:292844"
                     /db_xref="RGD:1307441"
                     /translation="MSLLMFLLSLLLDGSQGQMEKYFLQVQRIVKAQEGLCIFVPCSF
                     ISPENRWFNLYPEYGYWFKEIRRQSLQYPVATNNKDKGLEQGAPGRFQLLGDLSQKKC
                     SLLIKDVRWEDSTKYFFRIEKGYEKYSFKEAFTLQVEALTQKPDIFIPEILEPGQPVT
                     IVCLFSWNFEQCPAPSFSWMGAAASFQETRPHTSHYSVLSFTPGLQHNGTELTCQLDF
                     SRKSTQRTVQLRVAYAPRSLAISIFRDNVSVPELNRNPSHLEVQQGQSLRLLCTADSQ
                     PPATLSWVLEDRVLSWSSPVGSRTLALEMPWVKAGDSGHYTCQAENRLGSQQQTLDLS
                     VLYPPEDLRVTVSQENRTVLEILRNGTSLPVLEGQSLCLVCVTYSNPPASVSWFGATQ
                     TLIPTQSSEPGVLELPLVQREHEGELTCAAQSPLGTQRISLSLSVHYPPQMSRPSCSW
                     DSEGLHCSCSSRAWPAPSLRWRLGEGLLEGNSSNASFKVTSSSLGPWANSSLSLLQEL
                     EPSLWLSCEAWNTHGAQTTSVLLLPDKNSSAAFSKGAALGFGITALLALCLVVIIMKT
                     LQKKGTQEVTSRPKISRGSTILDYINVVPKTRSPARNWKAEPDTPSGISPLDTHSPKP
                     KKKQKDPRFTSPGFPDPRPSSQAPVSENNPEELHYAALNFPRLRLRETQNPQDTYSDY
                     AEVRVH"
     exon            210..587
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            588..866
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            867..914
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1178
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1226
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1484
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            1485..1769
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1857
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..1969
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2948
                     /gene="Siglec10"
                     /gene_synonym="Siglecg"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtttccagg ccagacatag ctctgtctct ccctcctagc cactggagat agctgggaag
       61 gatcagttcc aaatgtccaa gggccgaatg ctccacaaaa tgtggagtag gcaaaccagc
      121 tggggaagga ggccaacttg tacaagtcca agatcctcct aaggccacga tgtcactgct
      181 gatgtttctg ctatctttgc tgttggatgg gtctcaaggt cagatggaga aatacttcct
      241 acaggtgcag agaattgtga aggcacagga gggtttgtgt atcttcgtgc cctgctcctt
      301 catctcccct gagaatcgtt ggtttaactt gtacccagaa tatggctact ggttcaaaga
      361 aatcagaaga caatcacttc aatatccagt ggccacaaat aacaaagata aaggattaga
      421 acagggagcc ccagggcgat tccagctctt aggggatctc tcccaaaaga agtgttcttt
      481 gctaatcaaa gatgttcggt gggaagactc aacaaagtat ttcttccgga tagagaaagg
      541 atatgagaaa tacagtttta aggaggcgtt cacgctgcaa gtggaagccc tgactcagaa
      601 accagacatc ttcattcctg agatcctgga gcctgggcag ccagtgacca ttgtctgctt
      661 gttttcctgg aacttcgagc aatgcccagc tccttctttc tcctggatgg gggctgctgc
      721 ctccttccaa gaaaccagac cacacacctc ccattactca gtgctgagct ttaccccagg
      781 acttcaacac aatggtactg agctcacatg tcagctggac ttctctagga agagcacaca
      841 aaggactgtc caactaagag tggcctatgc ccccagatct cttgctatca gcattttccg
      901 tgacaatgta tcagtcccag aactgaatag gaatccttca catctggaag ttcaacaagg
      961 ccagtctcta cgtctcctct gtactgctga cagccagccc cctgctaccc tgagctgggt
     1021 tctagaggat cgagtccttt cttggtccag ccctgtgggg tctagaaccc tggcattgga
     1081 gatgccctgg gtgaaagctg gggactctgg acactacacc tgccaagcag agaacaggct
     1141 aggttcccag caacaaaccc tggacctctc tgtgctgtat ccaccagagg acctgagagt
     1201 gactgtttca caagaaaaca gaacagtgtt ggaaatcctc aggaatggca cctccctccc
     1261 agtcctggag ggccaaagcc tgtgcctagt gtgtgtcacc tatagcaatc ccccagccag
     1321 tgtgagctgg tttggggcga cacagaccct gatccccacc cagtcttcag agcctggggt
     1381 gctggagctg cctctggtcc agagagaaca tgaaggagaa ctcacctgtg ctgcacagag
     1441 cccactgggc acccagcgca tctctctgag cctctctgtg cactacccac cccagatgtc
     1501 cagaccctcc tgctcctggg attctgaggg tctgcactgc agctgctcct ccagagcctg
     1561 gcctgccccc tccttgcgct ggcggctggg ggaggggctg ctggagggaa acagcagcaa
     1621 tgcctccttc aaggtcacct ccagctcact tggaccctgg gccaacagct ccctgagcct
     1681 ccttcaggag ctggaaccca gcctctggct cagctgtgaa gcctggaaca cccatggggc
     1741 ccagaccacc tctgtcctgc tgctacctga taaaaacagt tccgcagcat tctccaaggg
     1801 agcagctttg ggctttggca ttacagccct ccttgccctc tgcctcgtcg tgatcatcat
     1861 gaagacccta cagaagaaag gaacccaaga ggtaacctca aggcccaaaa tctcacgggg
     1921 cagcacaatc ctggattaca tcaatgtggt ccccaagacc aggtccccgg ctcggaattg
     1981 gaaagctgaa ccagacaccc cttctgggat ttcgcccctg gacactcact cccctaaacc
     2041 aaagaagaag cagaaggacc cacgttttac atcccctggt ttcccagacc ccagaccatc
     2101 ctctcaggcc ccagtctctg aaaataaccc agaagaactc cattatgctg ctctcaactt
     2161 cccccgcctc agactacggg agacccagaa cccccaagac acctattctg attacgcaga
     2221 agtcagagtt cattgagggt gttctgggct ttacgactga gacctaaatg gtagagtagt
     2281 gaagagagag ggcctccaaa agaaagcata ttctctcctt aaaaataacc tgggggcagg
     2341 ggctgttaaa tgtgcttgcc accaagctcg atgaactctt cgattgatcc ccaggatccg
     2401 catggtggaa gtgacctccc acagtctttt gactcctcac atgagcatta tggctcacgc
     2461 ccttgcgtgc agacacacat aagttaataa acagatgtac aaaacaattt tttaaagatg
     2521 acagctcctg tttgggtatg ttctaagtgt gtctctcaaa ggcttacact cagagggaga
     2581 ggtgatgtgt gctctttcag gggtgggaca tggtagaaat gttaggtctt ggggcattgc
     2641 acagcctttg gaaggtgtca gtgctggtcc cacagagtgg accagttctc aagccaggag
     2701 gttacaagtt tggttgccaa gctctcttga tcttcccatg tcttatctct ctctcacgca
     2761 ctcacaccga gatgccatct gtcatactat ggtggaggca caggccttca tcaaagccta
     2821 tggaagagtt caaagtccca ctcaactgtt gctttcagtg agaaaaagcc cacccaaacc
     2881 cgtcttcagt gaagatgaag caagaagtcg gtcatcttaa atattgaaat aaaaggtaca
     2941 ctgatcaa
//
