LOCUS       NM_001191118            4866 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus siah E3 ubiquitin protein ligase family member 3
            (Siah3), mRNA.
ACCESSION   NM_001191118 XM_001080940
VERSION     NM_001191118.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4866)
  AUTHORS   Hasson,S.A., Kane,L.A., Yamano,K., Huang,C.H., Sliter,D.A.,
            Buehler,E., Wang,C., Heman-Ackah,S.M., Hessa,T., Guha,R.,
            Martin,S.E. and Youle,R.J.
  TITLE     High-content genome-wide RNAi screens identify regulators of parkin
            upstream of mitophagy
  JOURNAL   Nature 504 (7479), 291-295 (2013)
   PUBMED   24270810
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000015.1.
            
            On Sep 14, 2022 this sequence version replaced NM_001191118.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.58041.1,
                                           SRR26360194.611421.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-259               JAXUCZ010000015.1  57180245-57180503
            260-4866            JAXUCZ010000015.1  57243002-57247608
FEATURES             Location/Qualifiers
     source          1..4866
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q11"
     gene            1..4866
                     /gene="Siah3"
                     /note="siah E3 ubiquitin protein ligase family member 3"
                     /db_xref="GeneID:692004"
                     /db_xref="RGD:1592168"
     exon            1..259
                     /gene="Siah3"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..931
                     /gene="Siah3"
                     /note="seven in absentia homolog 3-like"
                     /codon_start=1
                     /product="seven in absentia homolog 3"
                     /protein_id="NP_001178047.1"
                     /db_xref="GeneID:692004"
                     /db_xref="RGD:1592168"
                     /translation="MLFFTQCFGAVLDLIHLRFQHYKAKRVFSAAGQLVCVVNPTNNL
                     KYVSSRRAITQNSAEQGSFHQHHLPHHHRHHCHHNHLYQHARPHHLHHQEPGLHSTQM
                     TPCICPLFSCQWEGHLEVVVPHLRQIHRIDILHGAEIVFLATDMHLPAPADWIIMHSC
                     LGHHFLLVLRKQERHEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRS
                     VLECVDSVITDGDCLVLNTSLAQLFSDNGSLAIGIAITETEVRARDAAEM"
     exon            260..4866
                     /gene="Siah3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatatgaag gcgcgctaag ccgggctgga gcggagtgtc tccgaggctg tgctccattc
       61 agagcccaag gacttacagc ttcctccgct gccttcctgt gccaacgacc ccccaaaagt
      121 tgtgatgctt ttctttacac agtgctttgg ggctgtgttg gatctcattc acctccggtt
      181 tcagcactac aaggctaaac gggttttctc tgctgctggg caacttgtct gtgtggtcaa
      241 ccccaccaac aatctaaagt atgtgtctag tagacgggcc atcactcaga actctgctga
      301 gcaaggtagc ttccaccagc accatcttcc ccaccaccat cgccaccact gtcaccacaa
      361 ccacctgtat cagcatgccc gtccccacca cctccaccac caggagcccg gactgcacag
      421 cactcagatg acaccctgca tttgccccct gttctcctgc caatgggaag ggcacctgga
      481 ggtggtggtc cctcacctgc ggcaaatcca caggatcgac atcctgcacg gggcggagat
      541 agtgttcctg gccacggaca tgcacctccc cgcgccagcc gattggatca tcatgcactc
      601 ctgcctcggc catcacttcc tgctggtgct caggaaacag gaacgacatg aagggcaccc
      661 tcagttcttt gctaccatga tgctgattgg gacccccaca caggccgact gcttcaccta
      721 tcgcctggag ctcaacagaa accacaggcg tctcaaatgg gaggccaccc cgagatccgt
      781 cctggagtgt gtggactcag tcatcaccga cggggactgc ctggttctca acacctcact
      841 ggcccagctt ttctctgaca atggcagcct cgccattgga atcgccatca ctgagacgga
      901 ggtcagagcc agggatgctg ctgagatgtg agaccaggag cggccggatc tcctgtgcac
      961 ctcggacctc tagacagcag gacctattaa ttacccttct ttcttttctt tctttttcgt
     1021 ctcaggtaat ttgaggtatt agtattcgtc tgccatgggc attatattat gtaaacaact
     1081 gtgattcaag atcttggtgt gaaatctgtc ctgtgttgtt ggtaaaattt tgtagaacat
     1141 tcagaagagt ctaccagaat agttatttcc caccattgtt agttcttttt ttcactgcct
     1201 ccaaagggaa cacgtaccac agttaccaag aagcagagca ctggagttaa aggctcccaa
     1261 acacatcctt ctttccctct tctggctgct tcagacagag cctgccttgt catgggtgaa
     1321 gcagcatgtc tcgggagaaa accctgacag ccatgatcga cccctttcca ggagccttgg
     1381 gctcaaggct aagctgcaga agcatgagac agtgtctcct ccacagaccg tggcgtcacc
     1441 tggaggcacc ctttgtgtca gaagcactca tttgatccag ggctggagac agtggtcaga
     1501 ttaaaagcct tctccttttt tcaggttttc ctggcctcct tactgagcca tgcctttccc
     1561 ttttactttg caattaaagc ccggatgttc tccctgcttt tcggaaaatc gctttgcctc
     1621 tgctgagatg caggctaagt aagatgcagg agaaaagcag ccagaaagaa ggcatggaat
     1681 taattttcta acagagggtg ctcctgcctc agtgagacct ttcaagtgta taaattataa
     1741 atccgtcagc ccccctcact agagtaacac tttttgtatc agagagccag ccactctgtt
     1801 cttgatagtt tataaataag atccatcatc aaaataagga ccccagagaa aagcaaagca
     1861 ggacctcccg cctggagagc tggccctgat acttgtcccc caccctgctg gcttctttcc
     1921 ttactctcta acacactctg tacataaata tggctgctta ggagttagct ctgcatgtgc
     1981 agaagggagc gtcacctcac cctccacttc cctcccctcc ccaacccacc aacccacaac
     2041 cttaccacca ccccctccac cttcttcacc ctcaccccct ccaccttcac cctcaccccc
     2101 tccaccttca ccctcacccc ctccaccttc accctcaccc cctccacctt caccctcacc
     2161 ccctccacct tcaccctcac cccctccacc ttcaccctca ccccctccac cttcaccctc
     2221 accccctcca ccctcaccct caccccctcc accttcaccc tcaccccctc caccttcacc
     2281 ctcaccccct ccaccctcac cctcaccccc tccaccctca ccctcacccc ctccaccctc
     2341 accctcaccc cctccaccct caccctcacc ccctccaccc tcaccctcac cccctccacc
     2401 ttcaccctca ccccctccac cttcaccctc accccctcca ccttcaccct caccccctcc
     2461 accttcaccc tcaccccctc caccttcacc ctcaccccct ccaccttcac cctcaccccc
     2521 tgacaccctc tccagaggtt gtttctcttg gtttgttgtt agaaccgtgc atgagcctct
     2581 agaggaaggc cttcgagcac tggaagaagg gggaggggct tcgctctgcc ttttttctgc
     2641 tctaacttgg acaccttaaa accttcccaa tgggaccacg tgtccacaac tcctttctgt
     2701 cactggccaa gtgctacggg gaaacatggc atccaaatcc agcacagctc tctccctggg
     2761 actgtgtggg cctctttcca actcattccc ttacctcagg cacaccagct gggccgggcc
     2821 agcctccaag cgaatgctta gtttgaggca gattgtcctg gctggccatc agcaatcttt
     2881 tctctaccag aattaatcca tctaaaaaca tactaccctt cccccacccc caccccaaac
     2941 tgagtgattt tccagccatt tttgctgtgg actcccaccc gaaacattga tagaaatatg
     3001 aaaatgcagt tctttccagt cacccagtca tttttgggac tctgagccca ggcttcatct
     3061 atctagggct ggagaagcac aactaacttt gcccatagag gagcacaaag acgaagctgt
     3121 gagttcccga ggaaaggctt gcatgcggca ggagctatca cacatgcagc tccaggccat
     3181 tagattccaa ccatggatgg cccagaccca aggctcgtgg gtcagccctg ggagggagca
     3241 gcttctgtgg ctccttgcct gcagcccagg cctccatagc catctaaagg cgtcagaagc
     3301 cgcagttcct tcctggcttc tgacggtcat ttggaacatc ataggtgccc caactaaaca
     3361 cacaacacct caagaagacg ctcagtgctt acacatcccg ggactcctgc aggttgcctg
     3421 tgccttccac tgagccgaac taggaacaac tgcaggctgt cattagtgca cactgtacta
     3481 tgggtaggtc atccaagcac agatttgaaa ggtggttcct aagatctcca aaataaaggc
     3541 taggaaatgt gtccttttcc tccatctacg gtgctcccaa aatggctttt ctctccaaac
     3601 gagtaagtga gaacagaaga caaaggagcc agctaaggcc agtgaattgg aaaccaaaaa
     3661 aagtgtgcat ttgatgtcat tgctaccaaa aggctctttt ctttagtctt gagtaaatcc
     3721 tcatcaggtt cctcaacaca caggttcaga gatgcatcat gaccttctca aggtcaaaca
     3781 tcagaccaca actaaaattc agccccacca acccagattt agtgttctcg atataggaag
     3841 acgaaccccc gatgtccagc agggtcttgc ttcagcagtg gattggagac ttgagaaccg
     3901 atcaggtctt caccctggat gatggagaat ccagatgatg gtggagaatc cagagggaag
     3961 actggagtgg aatccttctt tagtagcttc ttggccatgt gaagtaagct ggtcccaggg
     4021 ctgtgggagg gaagaggtgc atggaggtct cagtagcctg gtgtcccttt gtccccttca
     4081 cccactgtca ggcaagcgtc ttgctcctcc aggttgccaa gacactcaat ggtactcttt
     4141 gaggaatatg tgtgttttaa tagagggtct agacagacag tagcactgaa gagaaaatgg
     4201 gtcatctgta tttgaattgg caattgtgag ctgtttgttg ggaaggtgtt ttaaggggag
     4261 cctgcctccc cttgagtcag agcctaaatg aatgactgct ggaggttcac agtacaatga
     4321 agattgtaca tacatgtgtc agtcagtaca tacatgagcc tgtccccggg gtagacctaa
     4381 ctttcctgca gctcctgggg acattgagaa atgggccagg atagttgtca cagtaggcct
     4441 tgtggctgcc actgactgga agtttcccat atgaccccgg gggatattat cccatgtaat
     4501 cctcaaaaga atcacacgga gctgctgcta tgtgtaatat gttgtaccta tgtaactgag
     4561 aaattgcaga tagcaaacag taagactggt tccacagtct aggcttttaa ccaattccat
     4621 ccatgtcatt tctatgaact catgttgcag attctcagaa ggaccagtct ggacggcatg
     4681 gaaacgctgc tttagtgttt cagtactaag tgtatctttt tgcttctgtt cttccagtct
     4741 gatagctgac ttgtattcag attgttacat ttttagaatt ttgtaggtca gttattacaa
     4801 ccattattga agattaactt atatataatc ttacagttaa ataaattcta tttaagacaa
     4861 ggagaa
//
