LOCUS       NM_001271080            2300 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus Sh3kbp1 binding protein 1 (Shkbp1), mRNA.
ACCESSION   NM_001271080 XM_214873
VERSION     NM_001271080.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2300)
  AUTHORS   Feng,L., Wang,J.T., Jin,H., Qian,K. and Geng,J.G.
  TITLE     SH3KBP1-binding protein 1 prevents epidermal growth factor receptor
            degradation by the interruption of c-Cbl-CIN85 complex
  JOURNAL   Cell Biochem Funct 29 (7), 589-596 (2011)
   PUBMED   21830225
REFERENCE   2  (bases 1 to 2300)
  AUTHORS   Borinstein,S.C., Hyatt,M.A., Sykes,V.W., Straub,R.E., Lipkowitz,S.,
            Boulter,J. and Bogler,O.
  TITLE     SETA is a multifunctional adapter protein with three SH3 domains
            that binds Grb2, Cbl, and the novel SB1 proteins
  JOURNAL   Cell Signal 12 (11-12), 769-779 (2000)
   PUBMED   11152963
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Aug 31, 2012 this sequence version replaced XM_214873.6.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.1409.1,
                                           SRR26643287.808.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                JAXUCZ010000001.1  91777874-91777959   c
            87-140              JAXUCZ010000001.1  91777593-91777646   c
            141-186             JAXUCZ010000001.1  91777419-91777464   c
            187-260             JAXUCZ010000001.1  91777243-91777316   c
            261-319             JAXUCZ010000001.1  91776741-91776799   c
            320-400             JAXUCZ010000001.1  91776403-91776483   c
            401-562             JAXUCZ010000001.1  91775161-91775322   c
            563-653             JAXUCZ010000001.1  91774514-91774604   c
            654-844             JAXUCZ010000001.1  91774231-91774421   c
            845-960             JAXUCZ010000001.1  91773389-91773504   c
            961-1048            JAXUCZ010000001.1  91771734-91771821   c
            1049-1165           JAXUCZ010000001.1  91771532-91771648   c
            1166-1336           JAXUCZ010000001.1  91769802-91769972   c
            1337-1492           JAXUCZ010000001.1  91767081-91767236   c
            1493-1589           JAXUCZ010000001.1  91766556-91766652   c
            1590-1768           JAXUCZ010000001.1  91765471-91765649   c
            1769-1883           JAXUCZ010000001.1  91764940-91765054   c
            1884-2300           JAXUCZ010000001.1  91764426-91764842   c
FEATURES             Location/Qualifiers
     source          1..2300
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2300
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /note="Sh3kbp1 binding protein 1"
                     /db_xref="GeneID:292735"
                     /db_xref="RGD:1309281"
     CDS             1..2115
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /note="SETA-binding protein 1"
                     /codon_start=1
                     /product="SH3KBP1-binding protein 1"
                     /protein_id="NP_001258009.1"
                     /db_xref="GeneID:292735"
                     /db_xref="RGD:1309281"
                     /translation="MAVPTTAVEGVRSRGAPGEVIHLNVGGKRFSTSRQTLTWIPDSF
                     FSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYG
                     LTPLVRRLQVREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGPQQIGGRPAPVRR
                     SNTMPPNLGNAGLLGRMLDDRAPPSPSGQPEEPGMVRLVCGHHNWIAVAYTHFLVCYR
                     LKEASGWQLAFSSPRLDWPIERLALTARVLGGAPGEHDKMVAAATGSEILLWALQAQG
                     GGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAG
                     SFLLLGCSNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTSDSG
                     NWIEIAYGTSSGVVRVIVQHPETVGSGPQLFQTFSVHRSPVTKIMLSEKHLISVCADN
                     NHVRTWSVTRFRGMISTQPGSTPLASFKILALESADGLGGCSAGNDIGPYGERDDQQV
                     FIQKVVPNASQLFVRLSSTGQRVCSVRSVDGSATTAFTVLECEGSRRLGSRPRRYLLT
                     GQANGSLAMWDLTTAMDGLGQTPAGGLTEEELMDQLEQCELSPLTSSRASFPSPSPRT
                     SLTSLHSASSNTSLCGHRGSPSPPQAGARSRGAGSFVDRFKELARGAPELRGPPTPAP
                     RPSTSLGNPLILPKNTLNETSF"
     exon            1..86
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            87..140
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            141..186
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            187..260
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            261..319
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            320..400
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            401..562
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            563..653
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            654..844
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            845..960
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1048
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1165
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1336
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1492
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1589
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1768
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1769..1883
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1884..2300
                     /gene="Shkbp1"
                     /gene_synonym="RGD1309281; Sb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctgtcc cgacgactgc agtggagggg gtccggagtc ggggagcgcc cggggaagtg
       61 attcatctga acgtaggggg caagcggttc agcacctctc gccagacgct aacctggatc
      121 ccagactcct tcttttccag tcttttgagc ggacgtatct caaccctgaa agatgagacc
      181 ggagccatct tcatcgaccg ggaccccact gtctttgccc ccatcctcaa tttcctgagg
      241 accaaagagt tagaccccag gggtgtccat ggttccagcc tcctccatga agcccaattc
      301 tatgggctca ctccactggt tcgtcgcctg caggtaaggg aagagttgga tcgatcttcc
      361 tgcggaaatg tcctcttcaa tggttatcta cctcctccag tgttcccagt gaagcggaga
      421 aaccggcaca gcctggtggg gccccagcaa atagggggac gcccagcccc tgttcgacgg
      481 agcaacacga tgccccccaa cttgggtaat gcagggctgc taggccgaat gctggatgat
      541 agagcacctc catccccatc aggccaacca gaggaaccag ggatggtgcg gctggtgtgt
      601 ggtcaccaca actggattgc tgtggcgtat acccactttc tcgtctgtta tagactgaag
      661 gaagcctccg gttggcagct tgcattctcc agtcctcgcc tagactggcc cattgagcgc
      721 ctggctctca cagctcgggt gctcggtggt gctccaggcg agcatgacaa gatggtggct
      781 gcagccacag gcagcgagat ccttctgtgg gcgctacagg cacaaggtgg tggctctgag
      841 ataggtgtct tccacctggg tgtgcctgtg gaagccttgt tctttgttgg gaaccagctc
      901 attgccacaa gccacacagg gcgcatcggt gtctggaacg ccgtgaccaa gcactggcag
      961 gtccaggagg tccagcctat cacgagttat gatgcagccg gctccttcct cctcctgggc
     1021 tgcagcaatg gctccatcta ttatgtagat gtgcagaaat tccccctgcg catgaaggac
     1081 aacgacctcc ttgtcagtga gctctaccga gacccagcag aagatggggt caccgccctc
     1141 agcgtctacc tcacccccaa gaccagtgac agtgggaact ggattgagat tgcctatggc
     1201 accagctccg gagtggtgcg ggtcattgtc cagcaccccg agacagtggg ctcgggaccc
     1261 cagctcttcc agaccttcag tgtacaccgc agccctgtca ccaagatcat gctgtcagag
     1321 aagcacctca tctctgtgtg tgccgacaac aaccatgttc ggacgtggtc tgtgacccgc
     1381 tttcgaggca tgatctccac ccagcctggt tccactccac tggcatcctt caagatcctg
     1441 gcacttgaat cagccgatgg gctcggtggc tgcagtgctg gcaatgacat tggtccctat
     1501 ggtgagcggg atgaccagca ggtgttcatc cagaaggtgg taccaaatgc cagccagctg
     1561 tttgtgcgtc tctcctccac tgggcagcgg gtgtgttctg tacgctcagt ggatggctcc
     1621 gctacgactg ccttcacagt gttggagtgt gagggctcca ggcggttggg ctccagaccc
     1681 cgacgctacc tgctcaccgg ccaagccaat ggcagcctgg ccatgtggga cctgaccact
     1741 gccatggacg gcctgggcca aacccctgca ggcggcctga ccgaagaaga gctgatggac
     1801 caactggagc agtgtgaact gagcccattg acttcttctc gggcctcttt tcccagcccc
     1861 tcacccagaa cctctcttac cagtctacac tcagcctcca gcaacacctc gctgtgtggc
     1921 cacagaggga gccccagccc accgcaggca ggggcccgga gccgcggggc aggaagcttc
     1981 gtggatcggt ttaaagaact ggcaaggggt gcaccggagc tccgagggcc accaacacca
     2041 gcccctcgac cctccaccag tcttgggaat cccctgatac ttcccaaaaa cacacttaac
     2101 gaaacttcct tttgattcta gccacgaccg gctgtgcctt cttgtggact ggtcccaggg
     2161 gactcgggac tagggggagg ggaggcttcc tgttggagcc aggaactctt tagtgtgatc
     2221 ttggtcgcca agttcccgcc tctcttcttt tctaaaagcc aaagccactg tctctaataa
     2281 aatcctcact gccaactgtt
//
