LOCUS       NM_001145175            6089 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus shisa family member 7 (Shisa7), mRNA.
ACCESSION   NM_001145175 XM_001078232
VERSION     NM_001145175.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6089)
  AUTHORS   Han,W., Li,J., Pelkey,K.A., Pandey,S., Chen,X., Wang,Y.X., Wu,K.,
            Ge,L., Li,T., Castellano,D., Liu,C., Wu,L.G., Petralia,R.S.,
            Lynch,J.W., McBain,C.J. and Lu,W.
  TITLE     Shisa7 is a GABAA receptor auxiliary subunit controlling
            benzodiazepine actions
  JOURNAL   Science 366 (6462), 246-250 (2019)
   PUBMED   31601770
REFERENCE   2  (bases 1 to 6089)
  AUTHORS   Schmitz,L.J.M., Klaassen,R.V., Ruiperez-Alonso,M., Zamri,A.E.,
            Stroeder,J., Rao-Ruiz,P., Lodder,J.C., van der Loo,R.J.,
            Mansvelder,H.D., Smit,A.B. and Spijker,S.
  TITLE     The AMPA receptor-associated protein Shisa7 regulates hippocampal
            synaptic function and contextual memory
  JOURNAL   Elife 6, e24192 (2017)
   PUBMED   29199957
  REMARK    Erratum:[Elife. 2018 May 04;7:. PMID: 29726811]
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 18, 2009 this sequence version replaced XM_001078232.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMEA5760433 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                JAXUCZ010000001.1  78022831-78022921
            92-927              JAXUCZ010000001.1  78030401-78031236
            928-1082            JAXUCZ010000001.1  78032812-78032966
            1083-1133           JAXUCZ010000001.1  78035285-78035335
            1134-1283           JAXUCZ010000001.1  78036329-78036478
            1284-6089           JAXUCZ010000001.1  78036943-78041748
FEATURES             Location/Qualifiers
     source          1..6089
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..6089
                     /gene="Shisa7"
                     /note="shisa family member 7"
                     /db_xref="GeneID:691429"
                     /db_xref="RGD:1583944"
     exon            1..91
                     /gene="Shisa7"
                     /inference="alignment:Splign:2.1.0"
     exon            92..927
                     /gene="Shisa7"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..1924
                     /gene="Shisa7"
                     /note="shisa homolog 7"
                     /codon_start=1
                     /product="protein shisa-7 precursor"
                     /protein_id="NP_001138647.1"
                     /db_xref="GeneID:691429"
                     /db_xref="RGD:1583944"
                     /translation="MPALLLIGTVALLASTAGPVGARPSNDTSAVAPGPLPALLAHLR
                     RLTGALAGGGSAAGANANATKTSPAGGTGAAARAPPPAELCHGYYDVMGQYDATFNCS
                     TGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGP
                     GPGQAGWLEGGRAGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPR
                     AHREINVPRALVDILRHQAGPATRPDRARSSSLTPGLGGPESMAPRTPKNLYNTMKPS
                     NLDNLHYNVNSPKHRAATLDWRAMPPPSPSLHYSTLSCSRSFHNLSHLPPSYEAAVKS
                     ELNRYSSLKRLAEKDLDEAYLKRRHLEMPRGTLPLHALRRPGTGGGYRMDGWGGPEEL
                     GLAPAPNPRRVMSQEHLLGDGGRASRYEFTLPRARLVSQEHLLLSSPEALRQSREHLL
                     SPPRSPALPPDPTTRASLAASHSNLLLGPGGPPTPLHGLPPSGLHAHHHHALHGSPQP
                     AWMSDAGGGGGTLARRPPFQRQGTLEQLQFIPGHHLPQHLRTASKNEVTV"
     exon            928..1082
                     /gene="Shisa7"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1133
                     /gene="Shisa7"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1283
                     /gene="Shisa7"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..6089
                     /gene="Shisa7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctggcaga cacgcgctcg cgctgcctac cctggctggc ccccacgctg ccacccccga
       61 ttccctgaag gtcccgcatc cggaaagtga gtcctccctt cgtaaaaact tctgtacgcc
      121 cctcctccgt ccccgctaat tctttctttt ctcctgctga gcccttctct cgtcgctccc
      181 tttgccctcc cctcccaccg ctgcaattcg gctccgggat ccgcagcctg gcgtcccggt
      241 gtgcaccatg ccggccctgc tgttgatcgg gaccgtcgcg ctgctagcct ccaccgcggg
      301 cccggtgggg gcgcgcccat ccaacgacac aagcgccgtg gccccgggcc cgctgcccgc
      361 gctactcgcg cacctgcggc gcctgaccgg ggctctggcg ggcggcggga gcgcagcggg
      421 cgccaacgcc aacgccacca agaccagccc cgcgggtggc acgggtgcag cggcacgggc
      481 gccccctccg gccgagctct gccatggcta ctacgatgtc atgggccagt acgacgccac
      541 cttcaactgc agcaccggct cctaccgctt ctgctgtggc acctgccact accgtttctg
      601 ctgcgagcac cgccacatgc gcctggcgca ggcctcctgc tccaactacg acacaccacg
      661 ctgggccacc acgcccccgc cgctggctgg aggcgccggg ggcgctgggg gtgcgggtgg
      721 ggggccaggg ccaggccagg cagggtggct ggaagggggc agggccgggg gcgctggggg
      781 tcgtggggga gagggcccag ggggcagcac agcctacgtg gtgtgcggag tcatcagttt
      841 cgctctggcg gtgggcgtcg gtgccaaagt ggccttcagc aaggcgtcac gtgcgcccag
      901 ggcgcaccgg gagatcaacg tgcccagagc tctggtggat attctcaggc atcaagcagg
      961 acctgcaacc cgcccggacc gggccagaag cagttctctg accccagggc tgggaggccc
     1021 agagagcatg gcccctagga cgcccaagaa cctttacaac accatgaagc cctccaacct
     1081 tgataacctg cactacaacg tcaacagtcc caagcaccgc gccgccacac tggactggcg
     1141 tgctatgcca ccgcccagcc cttccctgca ctactctacg ctgtcctgct ctcgatcctt
     1201 ccacaacctc tctcatcttc ccccatcgta tgaggcggct gtgaaatcag aattgaatcg
     1261 atactcttcc ctcaagagac tggctgagaa agatctggat gaagcctacc tgaagcgcag
     1321 acatctagag atgccacgtg gaacactgcc tttgcatgca ctccggcggc caggcactgg
     1381 aggtggctac cgcatggatg gctggggtgg ccctgaggag ctgggcctgg caccggcacc
     1441 caacccccgg cgggttatgt cccaggagca cctgctgggt gatggcggcc gagcttcccg
     1501 ctatgagttc acattgcctc gagcgcgcct ggtgtctcaa gaacacctgc tgctatcctc
     1561 accggaggcg cttcgccaga gtcgcgagca cctgctgtca cccccacgaa gtcctgcact
     1621 gcccccagat cccaccaccc gggccagcct ggctgcctca cactccaacc tgctgctggg
     1681 gcctgggggc ccccccacac ccctgcatgg gttgcctcca tcaggcctgc atgcccacca
     1741 tcaccatgcc cttcatggct ctcctcagcc agcctggatg tctgatgcgg gcgggggtgg
     1801 gggcacactg gcccgcaggc caccctttca gcgccaggga accctggagc agctgcagtt
     1861 cattcctggg caccacttgc cccagcacct gcgcactgcc agcaagaacg aagtgactgt
     1921 ctgaggccgg gtgaagtgct gggggctgtg gcttccgagg cccccttctt ccagcccaga
     1981 tctccatcac aggcttatca tacacaccaa gggtctgaga ccagatgggc ccttggaccg
     2041 gagaccacgc ctccttttgg gatgttacag tagatgagat ctctcctcct actttgtcac
     2101 tatttgaacc aaggcctccc tcccatgatg tcatcccaga ggaaggaggc ctgtacatga
     2161 ggtcattgct agcaaatatg tctgtgtttt atgatgtcat tgcagggact aaacctcctt
     2221 cctatgaggt caccacagag gaagagccct gcctatgagg tcatcactag aggttatgtc
     2281 gattttgcat ggcatcacca cagagactcc tttcccgtga tgtcaccaca gacaatgcct
     2341 tgtcccatcc tgtcatccct agaaacaaaa atttcttcct gaagtgtcac tacggagata
     2401 agtctcacac ttcttgagac ttgttgacat catcctgact gagcgccgag gcctcttgca
     2461 attatcatca cgggaaacat gtttctctgc cgtggagaag atgccgccgc ctttccatga
     2521 tgccaccaca acagacaaag ccattttcct gggacacatt gcagggtacc atgccctgcc
     2581 aattttgtcc tcactaaaga ttaggcctcc tttccacaat gctgtcacgg gattttgcct
     2641 ccctcctgtg atgccatcac cagaataggt gccttgccca atgtcgccat cacagggacc
     2701 gtgcctcttc atgtgatgtc attaccaata atgaccacct gttcctggga cctctccagg
     2761 gtgaggccct tctgtggtgt ggccaccaga taacacccac ttggaaatga caccaggaga
     2821 cacctctatt tctctgccat gtcgtgagaa agttgggcat gtgtagccca agaccacctg
     2881 ggaagaggcc agagaaagta gtcggtcctg agatataata tgaagggtgt cggcactagg
     2941 gatgctaaga cagagatctg tctgtaggat gctggtgatg atgccctcca ttgcgtggac
     3001 atcatcatag agtgcttcca tctcagaggt ggtccccact ctagatgacc aatagtagtg
     3061 attgcataat gattatgtca tcagagtcct tatcttactt ccctataact aagtccgtgg
     3121 cttcttccca tgaccccagg gacatagcca acaggatgtc tactagcccc tctaaaggaa
     3181 cgttgggcct gtgcagtgag tccttgggga tggcacccat ggatgagctt cagctccaaa
     3241 gccactctga cccatgaggc ttctaaagtc gtaggactca taggtgagcc aaagggtggc
     3301 atcacttctt tctgccatat ctaaagatat caactctgtc aatagaggcc ccatctctac
     3361 tggaggggga gggttggggt aaatgtgctg ctgaccttac caatgatatt accattgaca
     3421 cccagtgtcc tcctttcata atggcatagc agtcggggtc caatgttaac tgtgtcattt
     3481 tccaggattc cataggactc acctcaacta ccatatcatc tcccaggcat tatcaccatt
     3541 aatggtatca tcattgtctc ccaagattcc tcccaaccat ggtgttatca tctcccaggg
     3601 ttcaaacaac atgttgtcat gatgtcccag gatccacaag cttgttctca tcgcttccca
     3661 gaatccttca caacatgctc acctcatcac ctcctgggat ccatcacagc ctggggggtc
     3721 tttatcatct cccagccatc tcaaccatac agtcctcacc atctcccagg atccatcaga
     3781 accatgctgt ccttacctct caggagccag tacaaccatg gtgtccttgt ctcccaggct
     3841 gtgcaatgga taatgatgtc ctcattttcc aaaaatccat tatgcctctc taccaggact
     3901 tgttaggact gatggagcca gtgtttctca taattcctta taattgcagt gtcacctccc
     3961 aggatccact ttaaccatgt cttcatgttt cagtagccac cacagctatg atgtcaccac
     4021 ttcataaaat ccattccaac tgtggtgtcc ttgtgttgtt acatcccagg atctatctga
     4081 taatgtcacg agtatcctat attcaatgag aatccatgaa aaccatcatt ctgtcacctc
     4141 cctggaccca tcaattatga cctatcatga ctcattggga ttaactgtta ccatggtgcc
     4201 atcacctcca agcagccata atagccaatg gtgtcttcat tccccaggac ccactttaac
     4261 cccagtgtct ccatgactta ggatttctga aatccagtga tatcatctct ccagtctacc
     4321 ataaccacag ttgtcatcac cttttggacc catgacagca aataatgtca tcttttccca
     4381 gagtacgctt cagccatggt gccatcctct cccagaatcc atgtaaaact gtgtgtcctc
     4441 atcttccagg acccatggca attgtgtgcc atctgccagg acccaccatc ttagggtcca
     4501 aatgctgtga caagctgtat ttcaattgtc ctctggggaa ccagcacaac aggccatttc
     4561 ccattccctc caatggactg gggtggagcc agctatctcc ctctgataat gtcaccctct
     4621 actctggccc ttcttaatcg tcactgcctc attcctgatc caaatagata tctggatcag
     4681 cttcacctac agacttggcc ttggccagct tccttccact cactggtgag tgcatccaaa
     4741 ctcttcttgg attaccactg tcccttgccc agccatctga tcggtgacag ggtcatctct
     4801 gtgacctctc cacagcagca acagagaggg agcttcccag cccttagatg gcatcactgc
     4861 cctacccaac tccatccctg gtacttggtc ccaaccagga tcagaacttg ctagcttgga
     4921 ccaagctctc tttagagagg atgtgtgagg tgccacagct gataaaccac ctgatggcct
     4981 agtcctgggc tgggtatatc cgagagcaat ggcccctgct acctttacct gaaaaggcca
     5041 agggtgctcc ttcgcccctt tccctaacat tccagggagt acccaggggc ttcaaggagt
     5101 ccctaatacc cagtgcacaa tcttaccctg ccacatccag ttctctgtac atatagccat
     5161 gtttcagggg ggcggccatt ccccactatt aaagggctac atgcccccct cccagcccct
     5221 aaggcaagga ggggggctct tctccctcct ctgggccgcc ctctccctct tatgcctccc
     5281 tcccccacca aatattggcc tctgtggcca tcccttcttg cccagagcct agatgggata
     5341 gatggtgcca ggctctcacc aagctgagga tagtaggagg ttaccaccaa tcttcctaaa
     5401 ctccagcacc aggttttctg tttcccaact atagatgctc tgtgggctcc ccatccattc
     5461 taggacctcc ctttaagcgt gcttaacact cccacggaac acacagcttt tttcagcccc
     5521 cagcattgga ggggttcagg agctttcagc ttttgtttgc ccgttctctc cctccctctt
     5581 tcccccaacc tgaattcctt cctgggatct gcccttaccc cagcctctgc cctccacctg
     5641 cctgaccctg gagtcttgac ctcttatttt aataaagcca tagtggggag aggtcttgag
     5701 ggtgggccag caggccctgt tctgctcatc ccccaccatc accacgatgc ttccagagct
     5761 ccagagcggg gacttagcct tctgagtctt cccctcccct tcccctctgc tccccagtaa
     5821 acacaaacac acatggacaa ggcatgcgct gccctgaagg aaagccccct tctggttggg
     5881 ggctgcagag ggggtgtcag agacaagatc aaaagtgcca caccagaggt tcctccacac
     5941 ctctgaaccc cattcttact cccctcctca ctcttcctcc ctgtgctgga ctcaccttca
     6001 acttcctggt gaggacagca agaggagctg gcacttggtt gggggtagag tgttgttttt
     6061 tgttttggaa taaacagctg ttttcctga
//
