LOCUS       NP_001138647             558 aa            linear   ROD 03-APR-2024
DEFINITION  protein shisa-7 precursor [Rattus norvegicus].
ACCESSION   NP_001138647 XP_001078232
VERSION     NP_001138647.1
DBSOURCE    REFSEQ: accession NM_001145175.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 558)
  AUTHORS   Han,W., Li,J., Pelkey,K.A., Pandey,S., Chen,X., Wang,Y.X., Wu,K.,
            Ge,L., Li,T., Castellano,D., Liu,C., Wu,L.G., Petralia,R.S.,
            Lynch,J.W., McBain,C.J. and Lu,W.
  TITLE     Shisa7 is a GABAA receptor auxiliary subunit controlling
            benzodiazepine actions
  JOURNAL   Science 366 (6462), 246-250 (2019)
   PUBMED   31601770
REFERENCE   2  (residues 1 to 558)
  AUTHORS   Schmitz,L.J.M., Klaassen,R.V., Ruiperez-Alonso,M., Zamri,A.E.,
            Stroeder,J., Rao-Ruiz,P., Lodder,J.C., van der Loo,R.J.,
            Mansvelder,H.D., Smit,A.B. and Spijker,S.
  TITLE     The AMPA receptor-associated protein Shisa7 regulates hippocampal
            synaptic function and contextual memory
  JOURNAL   Elife 6, e24192 (2017)
   PUBMED   29199957
  REMARK    Erratum:[Elife. 2018 May 04;7:. PMID: 29726811]
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 18, 2009 this sequence version replaced XP_001078232.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMEA5760433 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     Protein         1..558
                     /product="protein shisa-7 precursor"
                     /note="shisa homolog 7"
                     /calculated_mol_wt=56337
     sig_peptide     1..22
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2037
     Region          83..>136
                     /region_name="Shisa"
                     /note="Wnt and FGF inhibitory regulator; pfam13908"
                     /db_xref="CDD:464036"
     CDS             1..558
                     /gene="Shisa7"
                     /coded_by="NM_001145175.1:248..1924"
                     /db_xref="GeneID:691429"
                     /db_xref="RGD:1583944"
ORIGIN      
        1 mpallligtv allastagpv garpsndtsa vapgplpall ahlrrltgal agggsaagan
       61 anatktspag gtgaaarapp paelchgyyd vmgqydatfn cstgsyrfcc gtchyrfcce
      121 hrhmrlaqas csnydtprwa ttppplagga ggaggagggp gpgqagwleg graggaggrg
      181 gegpggstay vvcgvisfal avgvgakvaf skasraprah reinvpralv dilrhqagpa
      241 trpdrarsss ltpglggpes maprtpknly ntmkpsnldn lhynvnspkh raatldwram
      301 pppspslhys tlscsrsfhn lshlppsyea avkselnrys slkrlaekdl deaylkrrhl
      361 emprgtlplh alrrpgtggg yrmdgwggpe elglapapnp rrvmsqehll gdggrasrye
      421 ftlprarlvs qehlllsspe alrqsrehll spprspalpp dpttraslaa shsnlllgpg
      481 gpptplhglp psglhahhhh alhgspqpaw msdagggggt larrppfqrq gtleqlqfip
      541 ghhlpqhlrt asknevtv
//
