LOCUS       XM_006254817            4611 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus SH3 domain and tetratricopeptide
            repeats 2 (Sh3tc2), transcript variant X1, mRNA.
ACCESSION   XM_006254817
VERSION     XM_006254817.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006254817.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006254817.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4611
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4611
                     /gene="Sh3tc2"
                     /note="SH3 domain and tetratricopeptide repeats 2; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 ESTs, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 23 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:307393"
                     /db_xref="RGD:1309038"
     CDS             95..4093
                     /gene="Sh3tc2"
                     /codon_start=1
                     /product="SH3 domain and tetratricopeptide
                     repeat-containing protein 2 isoform X1"
                     /protein_id="XP_006254879.1"
                     /db_xref="GeneID:307393"
                     /db_xref="RGD:1309038"
                     /translation="MGGSQGSPDWRSQGPWPREDGAHMGGCFCIPGERSLPWGPGKEG
                     SSKDPPGLTEDISSLENKRKCFLPQNMTQDLVLSFWVRSRSRRCVNAALQEAARRRLW
                     ALENEAHEVHALFKDLSARLVSVQSQKDQFLITFKTLEEIWKFSTYLNLGYVSTCLEH
                     LFFDHTYWLNSRLVDDTEIQVSVDDTHLENIYLGLLLQEGHFFCRAMCSVTQPADKEG
                     EYLTLCKNELISVLSGGESDWEGMSLVTGQRGLVPVSALEPLPVSFHQWFLKNHPGIC
                     GLPRKKDWTGSCQIGRGRCKALMDYQQEERDELGFLQGESIDVIGFVIPGLRWFIGKS
                     MSSGKVGFVPTRSIDLDSCSPVSKNSVFFSDEERCSLWSPGGDRKAECSGFLSALAHT
                     DITSVYRLSEFESIQNLQNDLSASQPEGFREARSGGTWMERKTMGSRRSSSSLDSSLE
                     DELISASSDSYHLPEPDDLDDPELFMDLSTSLEEDEMEHFAPILAFLDHEGYTDHFKS
                     LYDFSFSFLTSSFYSFSEEDELVAYLETSRKWAKMTHRTWAHARLCFLLGRLSIRKTK
                     LSQARVYFEEAIRVLDGAFEDLSLVAALYINLAAIYLRQRLRHKGPILLEKAGALLAC
                     LPDREFSAKNELDVVTYVLRQGIVAGSGPLEARSCFLAIRLLLNLGRHEEVLPFAERL
                     QLLSGHSPASEVTATMLSSLYDKKYLPHLAVASVQKRGPQSARGMSVAIWQAYLVLQN
                     ATKILGVPFSSWCEVSALACPTLRQALAACEEQTDLNIQRTLCLLLSKMYLQHRSPDG
                     SVQYLSQAHVLGKLLGEEEAFESSLCLAWAYLLARQTKKALEILEPLLCSLRETECVT
                     QRGVVHNLLGLAFQDEGRTSRAAKSYLRALIRAREMGNIRNQAVSMANLGHLTLKSCM
                     QQSARGYLLQAVRLYSEIQASKETDMELVQVLLWLGQALVSGHQLVHSRLCYEMALLF
                     GLRHRHLNSQLQVTKSLCHFYSSVSPNPDACITYHEHWLALAQQLRDREMEGRLLESL
                     GQLYRNLNTSRSLRRSLACIKESLRIFVDLGERDKAAEAWLGAGRLHYLMQEDELVEV
                     YLQEAIQTALRSEELSLALKLYEEAGDVFFNGTRHRHRAVEYYRAGAVPLARRMKALR
                     TELRIFNKLTELQISLRGYEKALEFATLAARLSVLTGDQKQELVAFHRLATVYFSLNM
                     YEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYCRLGRLTFYQLKRGTGGEVKAHLTTM
                     PEQVAQGQRMHGLVASAKESRYRKGKTWNNCKQKRRFTDSHNWKLRCRFSFGYFWILF
                     LLQLHEYLLSPP"
ORIGIN      
        1 cactgcaggc cggatatcaa aggctgcatt gtgcattgaa ctgcctcggt ccccctcgtg
       61 tgccagggag gaggcgggag gagggacacc accgatggga ggctcccaag gttctcctga
      121 ctggcgttcc caggggcctt ggcccaggga ggatggtgca cacatgggtg gctgcttctg
      181 tatccctggg gagcggagtc taccctgggg cccaggtaaa gaaggttctt ccaaggatcc
      241 gcctggattg actgaggaca tatcctcact tgaaaacaag agaaaatgtt tcctgccaca
      301 gaatatgact caagacctgg tgctctcatt ctgggtgagg agtcgttcca ggaggtgtgt
      361 caacgcagcc ttacaggaag ctgcacggag gaggctctgg gccctggaga atgaagccca
      421 cgaagtccat gcactgttta aggatctctc tgcaaggttg gtgagtgtcc agtcccagaa
      481 ggaccagttc ctcatcacct tcaagaccct ggaggaaatc tggaagtttt ccacgtacct
      541 gaacttaggc tatgtgtcta catgtctgga acacctcttc tttgaccaca cgtactggct
      601 caacagcaga ctggtggacg acacagagat ccaagtgtct gtggacgaca ctcacttgga
      661 aaacatatac ctgggcctcc tgctgcagga aggtcacttc ttctgcagag ccatgtgctc
      721 tgtgactcag ccagctgaca aggaaggaga atatttgaca ttgtgtaaga acgagctgat
      781 ctccgtactc tctgggggcg aatccgactg ggaaggcatg tccttagtga cgggccagag
      841 gggcctggtg ccggtgtcag ccctggaacc cctgcctgtc tctttccacc aatggttcct
      901 aaagaatcac ccaggaatct gtggccttcc caggaagaaa gactggacag gctcctgtca
      961 gatcggcaga ggacggtgca aggctctgat ggattaccaa caggaggaaa gggacgaact
     1021 gggcttcctc cagggtgaaa gcattgacgt catcggcttt gtcatacctg ggctgcggtg
     1081 gttcattggg aagtcaatga gctcaggaaa agtgggcttt gtccccacca ggagcataga
     1141 tctcgattcc tgctccccgg tgagcaagaa ctctgtcttt ttcagtgatg aggaaaggtg
     1201 ttctctctgg tccccaggag gtgacaggaa ggctgagtgc tctggcttcc taagcgcact
     1261 cgctcatact gacatcacct ctgtctaccg gctgagtgag tttgaatcca tccagaatct
     1321 tcagaatgac ttgagcgcat ctcagcccga gggcttcagg gaggccaggt ctggtgggac
     1381 ctggatggag cggaagacca tgggctccag acgttccagc agttctctag actccagcct
     1441 tgaggatgag ctcatctcag cctcctcaga cagctatcac cttccagagc ctgatgacct
     1501 cgatgacccg gaactgttca tggacctaag cactagcctg gaagaggatg agatggagca
     1561 ctttgccccc atcttggctt ttctagatca tgaaggctac actgaccact tcaagagcct
     1621 ctatgatttc tccttctctt ttcttacttc gtccttttac agcttctctg aggaggatga
     1681 gctagtggcc tacctagaga cttcaaggaa gtgggccaag atgacccaca ggacgtgggc
     1741 ccatgcccgg ctctgcttcc tcctgggcag actaagcatc aggaagacca aactttccca
     1801 ggccagggta tactttgagg aggccattcg agtccttgac ggggcgttcg aggacctctc
     1861 cctggtggct gctctgtaca tcaacttggc agccatctac ctgaggcaga ggctaagaca
     1921 taaagggcca atcctgctgg aaaaggcagg tgctctgctg gcctgcctgc cagaccgtga
     1981 gttcagtgcc aagaatgagc ttgacgtggt gacttatgtg cttcgccaag ggatcgtggc
     2041 ggggagtggc cctctggagg ctaggtcctg cttcctggcc atccggttgc tcctgaatct
     2101 tggccggcat gaggaagttc tgccatttgc agagcgtctg cagctccttt ctggacactc
     2161 tcctgcttcg gaggttacag ccaccatgtt gagttctctg tatgacaaga aatatcttcc
     2221 acatcttgca gtggcctccg ttcagaaacg tggtccccag agtgcccggg ggatgtctgt
     2281 tgccatttgg caggcttatt tggttctcca gaatgccaca aagatcctgg gtgttccttt
     2341 ttcaagctgg tgtgaagttt ctgcactggc ctgcccaacc ctcaggcagg ccctggctgc
     2401 ctgtgaggaa cagactgacc tgaacatcca gaggaccttg tgtctcctcc tgtccaaaat
     2461 gtacctccag cacaggtctc ctgatggttc tgtccaatac ctgagtcaag cacatgtgtt
     2521 agggaaactc ctgggtgaag aggaagcctt tgaatcttct ctctgtctgg catgggctta
     2581 tctcttagcc aggcagacga agaaggcttt ggagatcctc gaaccgctac tgtgttcctt
     2641 gagggagaca gagtgtgtga cccagagggg agtggtccat aacctcctgg gactggcctt
     2701 tcaagatgaa ggtcggacaa gcagggcagc caagagctat ctccgagctt tgatcagagc
     2761 tcgggagatg gggaatatac gtaaccaggc tgtgtctatg gccaatcttg gtcacttgac
     2821 cctcaagtcc tgtatgcagc agtcagccag gggttatctc ctgcaggctg tccgactgta
     2881 ttctgaaatc caagccagca aggagacaga tatggaattg gtacaagtgt tactctggtt
     2941 gggccaagct ctggtgtctg gacaccagct ggtccacagc cgcctttgtt atgaaatggc
     3001 actgctattt ggcttaaggc accgacacct aaacagtcaa cttcaggtca ccaaatccct
     3061 ctgccatttc tacagctccg tgtccccaaa ccctgacgcg tgcattacct atcatgaaca
     3121 ctggctggcc ttggctcaac aactcaggga ccgggagatg gaggggcggt tactggagtc
     3181 ccttgggcag ctttatagga acctaaatac atccaggtcc ctcagaaggt ccctcgcctg
     3241 catcaaggag agcctgcgga tattcgtcga cctaggggag agagacaagg ctgctgaggc
     3301 ctggctgggg gccgggcgcc tgcactacct catgcaggaa gacgagctgg tggaagtgta
     3361 tttgcaggag gccatccaga cagccttgag gtcagaagag ctctccctcg ctctcaagct
     3421 ttatgaagaa gcaggtgatg tgttcttcaa tgggacccgc catagacatc gggctgtgga
     3481 gtattaccgg gctggggctg ttcctttagc gaggagaatg aaggccctgc gaaccgagct
     3541 gcggatcttc aacaagctga cggagctgca gatcagcctc cggggctatg aaaaagcttt
     3601 ggaatttgcc actctggctg ccaggctgag tgtcctcaca ggagatcaga aacaggagct
     3661 ggtggctttt caccgcctgg cgaccgtgta cttctctctg aacatgtatg agatggctga
     3721 agactgctac ctgaagactc tatccctgtg cccgccatgg ctgcagagtc ccaaggaagc
     3781 gctgtactat gccaaggtgt attgtcgcct gggccgactc actttctacc agctgaagag
     3841 agggacaggc ggcgaggtga aggcccactt aaccaccatg ccagagcaag tggctcaggg
     3901 acagagaatg catggtctgg ttgcatcagc caaggagtct aggtaccgca aagggaaaac
     3961 ctggaacaac tgtaaacaga agaggcggtt tactgactcc cataactgga agctgaggtg
     4021 cagatttagt tttgggtact tctggattct attcctcctt caacttcatg aatacctctt
     4081 atctcctcct tgacgctgtg tgttcctact tctctgtgac tcttggcctc aatctttgcc
     4141 agcccctggg agactgatgc catattcaaa aggaaatcgg ccattttcct tgttgggtta
     4201 caccaaaaag tcccagaggg gggtggactg tccagtgcaa tgttgtatct tgattggaga
     4261 cggggaagat gccacctctg tgcctgagga ggagggacac tgtgattggt aatgccatca
     4321 gagcctgagt acatcaaggg aagacctcct ttgaggcatt gggatgtggg gatggagtaa
     4381 ctgaacaatg tcaatgatct cagcatagag cttaagcctg tcctgtaagt actgctaatg
     4441 atgtctcttc tttgccccat ggggttagga tgcccatgat gctactgaat actttttgct
     4501 ggcactagca gctgcggtcc tggtgggtga cgaggagctg caggacacca ttaagaacag
     4561 gctagacagc atctgccaga gtcccttgtg gcacagcaaa cccttggggt g
//
