LOCUS       XM_017593853            5431 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus SH2 domain containing 5 (Sh2d5),
            transcript variant X1, mRNA.
ACCESSION   XM_017593853
VERSION     XM_017593853.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_017593853.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5431
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5431
                     /gene="Sh2d5"
                     /note="SH2 domain containing 5; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 6
                     ESTs, 4 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 52 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:366489"
                     /db_xref="RGD:1305952"
     CDS             2452..3741
                     /gene="Sh2d5"
                     /codon_start=1
                     /product="SH2 domain-containing protein 5 isoform X1"
                     /protein_id="XP_017449342.1"
                     /db_xref="GeneID:366489"
                     /db_xref="RGD:1305952"
                     /translation="MQRAGAGARRASDCGPAPYRPRCIAKFAQYVGSFPVDDLDTQES
                     VCLVQQHLWALQDCSRRRAVILKFSLQGLKIYSGEGEVLLMAHALKRILYATWNPAAC
                     QFAFVARNPRSPASKLFCHLFVGSQPGEINILYLLLCRSFQLAYLLQHPEERAQPEPS
                     LVPGGDMSLKPLCSPGVAPALVREPFSRDQLSQNVHALVSFRRLPAEGLLGSNGKELP
                     EPEGRGGTRHIRLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAA
                     WEAWPRGPGSPSCLVENEGSLTENIWAFAGLSRSCALALLRRDVHGAFLLWPEPGTSG
                     QWSLSVRTQCGVVSHQVFRNHLGRYCLEHLPAEFPSLEALVESHAGMERSLFCPLSMG
                     RLNPTYEEQDSGPEGRFPRTLRPLSHAKSEAELQGLG"
ORIGIN      
        1 cctgttttgg gggaggctaa atatgaggat gctgtccatc ctccccaccc ccttccctaa
       61 ctcagtgccc acagggcact tggcaagctg ctctctctct ctctctctct ctctctctct
      121 ctctctctct ctctctctct ctctgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtctgtgt
      181 ctgtgtctgt gtctgtgtgt gtgtgtgtgt ttgctgaccc ttggctcttt accccgtgtt
      241 tgccaggctg ttgcgcaagc agggtgtgaa gggctcttgt cagccctctt tgtctctttt
      301 ttttttttaa gatttattta tttattatat ataagtccac tgtaactgtc ttcagataca
      361 cacgaggtac agacaagggc atcagatctc tttacagatg gatatgagcc accatgtggt
      421 tgctgggaat tgaactcagg acctctggaa gagcagacag tgctcttaac cactgagcca
      481 tctctccagc cctctttgtc tcttttgagg ttgcttttct tctcaccctg ttccatcccc
      541 gcccccgccc cccacgctcc cccttccttg tgggtctcct tgccagctgc gtgtcttgtg
      601 gtctctgctt ccttgctctc ttctgcctga aagtgaagac gcacttccct gcctccctgg
      661 gagccccgtg gtccccctgc tgggaagggg caggcagcac gtggcaggag tgtggtctgc
      721 tttatgtaaa catcagatgt gccatcgaga caggcgactg taaagtgagc gggcttagaa
      781 aggaaggttg gcagagcgca ggttgacagc agccttgcgg aggcctgggt gggctctggg
      841 ggaggggcgg ggctactgcc tctgttttcc ccgctctccc tggctgaagt ctggctggaa
      901 ggtcactggc aggcagaggt gtagggccct tttggggttc taagagcatc aatctaaggc
      961 gcccaagctc ctcccttttc caagcactcc cgccgctgtg tcacttccag gactactaac
     1021 tcctgctttc tcctgtgagt caaagcctcc aggccaactt ctttccagcc tgactttcac
     1081 agtggctgag ggtttccagt tggtgtagcc tggacaggaa gtcttgaaag aagctagact
     1141 ctgctgccat cttcccaagc tcccttccgg tcagcaggct tggaggtctg atcccctgct
     1201 ccatgtcagg ctggcatctc gccaggcacc tcacgttacc caaggttttc aggaaaggaa
     1261 gtgagtgcat agagaggtag ggcagctggc ccaaagccac acagaacttg tgcctctctg
     1321 acccgagcca atgattgcaa gaaggttgga gagaatccgg gagagggcag gtgtcttaca
     1381 gtgtccctga ggatgctgag tttgcaggga cccaagcata gactttcccc caacgactgg
     1441 tccattgacg catctgtcac acaggacttc tgtcttccac ctgtgcatct ggctaagggt
     1501 cccagggaaa ccaaaacagg accaggcagg agtgctgttt gtccatctcc tgggcccatg
     1561 tccgtcttct ctgcactccc ctcagcacca gcgcttcgtt gtcaagggtt gtgggtttca
     1621 tactctgcca agggctttgg gattcaggaa cggagtcagg ctgggcacat gagccagcag
     1681 cctttcgaac cggcccctga gatcatctaa gggagctgtc cagctccgga ccacccaccc
     1741 tccatcccca cccccacccc tgtgcactgt tcctgcccca gggccagcta tggcttcccc
     1801 accgtccaca gggttaagtc tcgttcttgg gctgatcttg ggtgctgtgc agcctgctgc
     1861 tttggtaatc tgcctcaggc cccagctcag gttttttctg ccttctcttc ttgctacagt
     1921 taacccctac ctttcgatgg actcttccgg actcctgctc tccctatgag acctgttttg
     1981 attttttttg ggggggggag tgtctcgtgt tgggggggtc ttctattgtc cagcctatcc
     2041 ctgaactcct gggttcaaat gacttggtcc tcctgcctta gcttcctgag aagtttgaac
     2101 tgtaggcaga cgtcagttct ttcaagcact aacaactggt tttatttttc taccagctcc
     2161 ctgcgcccat ccctgccaca gagggcccag tgagcgctct aaccccagat ctggctcagc
     2221 gacccatgcc aggaaccatc ccactctgac cgctccccac acaccaccca gtgcagcccc
     2281 agcccctcct gttgcctctc tccgtcttcc caccgtctca cctgattaag gcttattctc
     2341 gagttccccc accttgctcc ccaagcagac agaattggtc ttttgtccct gtcacatgcc
     2401 caggacactg cctcctctcc gcgaatcgtg aagctgggta cgctggggac catgcagagg
     2461 gctggggccg gggcccgaag ggcctccgac tgtgggcctg caccctaccg gcccaggtgc
     2521 attgccaagt tcgcccagta cgtgggatcc tttcctgtgg atgatttgga cactcaggag
     2581 agcgtgtgcc ttgtacagca gcatctgtgg gccctgcagg actgttcccg acgccgggcc
     2641 gtcatcctga aattcagtct tcagggtctc aagatctaca gtggggaggg cgaggtgctc
     2701 ctcatggccc atgctctgaa gcgcatcctc tatgccacct ggaacccagc cgcctgccag
     2761 tttgcttttg ttgcccggaa cccacgcagc ccagccagca agcttttctg tcatctcttt
     2821 gtggggagcc agcctggaga gattaatatc ctgtacctgc tgctctgccg atccttccag
     2881 cttgcttacc tcttgcaaca ccctgaggag agggcgcagc ctgagccctc cctggtgcct
     2941 ggaggggaca tgtccctgaa gccgctctgc agccctgggg tggcccctgc gttagtgcgg
     3001 gagcccttca gccgggatca gctgtcacag aatgtccatg ccctggtgtc cttccggcgg
     3061 cttcctgcag aagggctact gggcagtaat gggaaggagc tgccagagcc agagggccgt
     3121 gggggcaccc gtcacattcg tctagggaac ccctactgct cacccacact ggtgcgcaag
     3181 aaggccattc gcagcaaggt gatccgctcc ggggcctacc gaggctgcac ctatgagaca
     3241 caactgcagc tgtcagcccg ggaagccttt cctgctgcat gggaggcatg gccccgtggc
     3301 cctggtagcc cctcgtgcct ggtggagaat gagggaagcc tgacagagaa catctgggcc
     3361 tttgctggcc tttccaggtc ctgtgctctt gccctgcttc ggagagatgt gcatggggcc
     3421 ttcctgctgt ggcccgagcc aggtaccagt ggccagtgga gcctgtctgt ccggacccag
     3481 tgtggcgtgg tgtctcacca ggtcttcaga aaccacctag gccggtactg cctagagcac
     3541 ctgcctgcag agttccccag cctggaggcc ctggtggaga gccacgccgg gatggaacgc
     3601 agcctcttct gtccactcag catgggccgg ctcaacccta cctacgaaga gcaggactcc
     3661 ggtcctgagg gcaggttccc acggactctg cggcccctca gccatgccaa gtctgaggca
     3721 gaattgcaag gcctgggcta gcacacagcc agccctcagt cccctgtggg cccagccttg
     3781 ccttggcccc tgggtggcaa cggtcattct gcccttcttg caccccaccc actggtcacc
     3841 agctccagac aggtcaatct gccccttgat tggcccttcc atcacttcac tgccatggga
     3901 gaggagccct gaggttggag gtggagataa caggacctct cccaggacct ggggccagct
     3961 gaggtaccag gatgaacatg tagagccaga gggctggtaa ctctagatga ctttggggaa
     4021 gtggccactg ctaggttcct actgtccttg tgcagaggct tccccagcag ttcatgatgt
     4081 gggtgcagtc tttgctggag gaggcgaagc ctctgctggg tggggaaccc cagaacgctc
     4141 cccataggga accagagcct tagggagttt ctggcttgca ccttcagctc atttcctgga
     4201 gtcactttga gtggggctag tagtgagcac accgcagtcg gcttggtggc tgctttagga
     4261 agtcacttaa tgctggtgtt tcctctaaca cagagctgac cgttgggcat ggctggcact
     4321 gatcacctca gccctgtttg cggtggagaa ctaggattaa tgcaagcctc atggagggga
     4381 ggtgacctta gcaagggcca gtccagggac atatcctaga gggtctagcc agggaatgac
     4441 aaattcaagt gtcccttaaa tcaactctgc agaatatatg aatctaccca aaagaacaaa
     4501 cttttttttt tctttttttc ggagccgggg accgaaccca gggccttgct cttgctaggc
     4561 aagcgctcta ccactgagct aaatccccaa ccccaagaac aaacttctta agtggtggca
     4621 gtgcccacct ttagtcccaa tgtttagagg gtggaggcag acagatctct aggagtttga
     4681 ggccagcctg gtctacagag gaagttccag gacatccagg gctactctgc gaaaccctgc
     4741 ctcaaaaaat aaaataaaat aaaaaacaac aacaagacag attagctttg gaagcagagg
     4801 tgtgggcaga gaggagggat gtccttgttt agtgccttgg atgccacagg tttcagtgga
     4861 agccacaggt tttggatttc ggatccaagc ccttagctca gtacagtgcc atttctttca
     4921 agtgagaggt atcttgtgag ggatggagag aaaggtgcct gcggaactcc ttcactggag
     4981 acactaccac ctctagactg atgatgagca gtaatccttc tgtgccatgc ccaccaccat
     5041 gcctgctccc tgagtagggc ctggttccca ctgagctgag agattagcat atcttgtgcc
     5101 ccgccccaga gagttccacc caaggaaact tgttaacaac ttggcccaga tgctagtcca
     5161 gggctcacca actggagggt tcgtagtgtg aatcacccat gtgtacgata ccaggagaca
     5221 ctccacacag ccaagggacc agccttcccc atgccctttt gacattcttt ccaaagcatt
     5281 tattgatcgc atggtacaaa cagcaccgtc tggagcccct gtgttcagac agtgtctttc
     5341 ttacaggcca tggctctgtc tctgtgcaga ccaccaccac ggctctcctg tgtgcactct
     5401 gagacaaata aaccacattc ttcacagtcc a
//
