LOCUS       NM_001170349            5286 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus SH2 domain containing 4B (Sh2d4b), mRNA.
ACCESSION   NM_001170349 XM_237966
VERSION     NM_001170349.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5286)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Aug 30, 2022 this sequence version replaced NM_001170349.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-512               JAXUCZ010000016.1  16803006-16803517   c
            513-672             JAXUCZ010000016.1  16781077-16781236   c
            673-820             JAXUCZ010000016.1  16779569-16779716   c
            821-968             JAXUCZ010000016.1  16762401-16762548   c
            969-1185            JAXUCZ010000016.1  16748969-16749185   c
            1186-1310           JAXUCZ010000016.1  16746692-16746816   c
            1311-1531           JAXUCZ010000016.1  16718408-16718628   c
            1532-5286           JAXUCZ010000016.1  16708645-16712399   c
FEATURES             Location/Qualifiers
     source          1..5286
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..5286
                     /gene="Sh2d4b"
                     /note="SH2 domain containing 4B"
                     /db_xref="GeneID:290612"
                     /db_xref="RGD:1311591"
     exon            1..512
                     /gene="Sh2d4b"
                     /inference="alignment:Splign:2.1.0"
     CDS             329..1624
                     /gene="Sh2d4b"
                     /codon_start=1
                     /product="SH2 domain-containing protein 4B"
                     /protein_id="NP_001163820.1"
                     /db_xref="GeneID:290612"
                     /db_xref="RGD:1311591"
                     /translation="MLQQILQDMYIDPELLAELSDVQKHILFYKMREEQLRRWREREA
                     WDALAQAEGLRPAKVKRASNKHIQWLLGADGEVWVWVMGEGPGDKPYEEISEELIAER
                     ARLQAQKEAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRKAAKVLEERIH
                     EEFKRKEEEERRRGEEQIRLQEEQRAKELYWTLKQAQLHCQDSENEEREWEEQLRRSK
                     AADEERSRRAQRARDEYRRHSLRAIQKGTVAGLSTMFQELGQNHEQEARLYHQLPGTR
                     PPSPLTGPDRTWERPLRPLSREVIVRWFKEEQLPRRAGFERNTKSIAPWFHGIISREN
                     AEDLLENMTEGAFLVRVSEKIWGYTLSYRLQRGFKHFLVDASGDFYSFLGVDPNRHAT
                     LTDLIDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE"
     exon            513..672
                     /gene="Sh2d4b"
                     /inference="alignment:Splign:2.1.0"
     exon            673..820
                     /gene="Sh2d4b"
                     /inference="alignment:Splign:2.1.0"
     exon            821..968
                     /gene="Sh2d4b"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1185
                     /gene="Sh2d4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1310
                     /gene="Sh2d4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1531
                     /gene="Sh2d4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1532..5286
                     /gene="Sh2d4b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaccccaggg aaagccacaa cataaggtgt tgctgaaacg cagtgatcta atgataagtg
       61 atcttgatag gaacccaggg ccagatagct cctctcagag cttggttctt gctgcgtggg
      121 ctgaacaatg ccaacctggc cgatatgaat tcatcactgg ctgggagctg agacagaaca
      181 aagatgctat acaagaaaag gatatctgga gtggttccaa aatgaggagc tagggcagaa
      241 ttggctcgag gccttggcct ggccggggga tctgcctggc cctggagttc tgactggctg
      301 cactccagtg tgtgtcccgg acagcatcat gctgcagcag atcctgcaag acatgtacat
      361 cgacccagag cttctggctg agctcagtga tgtgcaaaag cacatcctct tctataagat
      421 gcgagaggag cagcttcgac gttggaggga acgggaggca tgggatgccc tggctcaggc
      481 agagggcctc aggccggcaa aggtcaagag agcgagcaac aagcacatcc aatggctgct
      541 gggagcggat ggcgaggtct gggtgtgggt catgggagaa ggccctggag acaagcccta
      601 cgaagagata tctgaggaac tgattgcaga gagggctcgg ctgcaagcac agaaagaggc
      661 cgaagagctc tggagacaga aggaagcaga gatcaccaaa aagttccggg atgccttggc
      721 caatgagaaa gcccggattc tggcggagaa gtggaaagtg gagatggagg accgcaaggc
      781 tgctaaagtc ctggaggaac ggatacatga ggaattcaag aggaaagagg aagaagagag
      841 gaggcgaggg gaagaacaga ttcgactcca agaggaacag agggcaaagg aactctactg
      901 gaccctgaag caggcccagt tacactgcca agacagtgag aacgaggagc gtgaatggga
      961 agaacagctg cgtagatcca aggcagctga tgaggagaga agccgtcgtg ctcagcgagc
     1021 ccgggatgag taccggcgcc actcactccg agccatccag aagggcactg ttgctggtct
     1081 aagcaccatg ttccaagaac ttggtcagaa ccatgagcag gaggcaagac tctatcacca
     1141 acttcctggc accaggccac catcacccct cacaggacct gacaggacct gggagcgacc
     1201 tctgcgtcca ctctctagag aagttattgt gcgctggttc aaggaggaac agctgcctcg
     1261 ccgagctggc tttgaaagga acacgaagtc catcgctccc tggtttcatg gaattattag
     1321 ccgagagaat gcagaagacc ttctggagaa tatgaccgag ggagcatttt tagtccgggt
     1381 cagtgagaag atctggggtt ataccctgtc ctaccgcctg cagagaggtt tcaaacattt
     1441 ccttgtggat gcctctgggg acttctacag ctttctggga gtggacccta accgccatgc
     1501 caccctaaca gatctcatcg atttccacaa ggaggaaatc atcaccgttt cagggggaga
     1561 gttgctacag gagccctgcg gacagaggga tagcccacca gactatcacc tgttgtttga
     1621 atgatttttt tccctcctct ttggactcct ttgagtatcc tgattttaaa ctgagcttaa
     1681 taaggtccca actcaaagcc tcatggcatt ctggaagatc caccattctt cagatgaaca
     1741 attgtagtac cgagcctcca ggatgtgacc tatgaaatgt gactacattt gtgatactgg
     1801 tcccattcca aagctcaaga cagaaacccc aaataacgat gcatctggag gcctgtctgt
     1861 catggctgtg ctaatctgaa ctccgagagt gaatgggtca tgttttagta acccaagtaa
     1921 ttccagtgcc gaaccttcca tttaatatag agccagtact caattaatta tttgttgagt
     1981 gaatgccctt ctgaaaaact cccaacatca atgacttcta gcaaattatt ttctatacca
     2041 ctccataaag tcatagagat aacggaagca ggcttgtgac taacttccat gtaaggcata
     2101 catattgcat ctttcctact gttcagggac ttgttgatat tatcatgggc gttacccaag
     2161 gttgctatgc ttggctttca ggacagagga ttaatgttgc gctagctgcc ttgttgaatc
     2221 acttctacct ctctcttcta tctcacatgt ggctctggtt tttcaaattt gtggtaatga
     2281 tgtcatgtga atgtgcagaa tatctggatg gattataaat ccaaggatgg tgttttgata
     2341 cttgacgagg caggcctttg ctgtctagaa tgttctctgt gtgctctcta cttaaaggct
     2401 ttagtatgtt tcatttcatt ttatttttat ttcttccatc tgaacatgtt cttcatatta
     2461 atgagaataa cctcccaata acttagtaac tctcaaggat ggagtctatc ttagggcttt
     2521 actgatgcaa agagacacca tgaacataac aactcttaaa gtaaaacatt taattgaggc
     2581 tggtttgtgg tttcagaggt tcagtcagtc gtcgccatga tggggaccat ggcactttat
     2641 aagcagacac ggtttgggag aagagttcta catcttgatc tgaaggcaac tggcagagag
     2701 cctgtcttct aggcagctag ggggaggatc tcaaggccca cccctgccgt gaggcaactt
     2761 cctccagcaa ggccacatgt attccaacaa ggccatacct cccaataatg gatcagcata
     2821 ttcaaaccag cacagtgtct aatgctagca cagtcatgcc cccttatgat gatagtcaag
     2881 gagatagcag atgtcacagc aagattgcag gttctgaaat ctggaaggtt tcagttccaa
     2941 tccacactct gaaactttgt gacattataa tccttatagc actgggtttg gcatttataa
     3001 aagaatagat ggactctgga aacaccagga aactgtttta tctgccttga gagtcgtgtc
     3061 ataagaagaa taaggtgtct ttgtcctcca ctcaacctct tggctcttgt ttcttgcatc
     3121 cttgtccact tgtaccatca cccaccctca tggctattgt tacagccagt tttgggaatg
     3181 actctgcttt cgttcgttca ccatattctc cagactcctg tgtacatatg ccaatggtgc
     3241 tttgccacac acacggttct ttggggggag gatttattta gttattatcc tttaaactgt
     3301 tttttcttta ttcttgagaa tttcatacat ctatacaatg aaaaatttac tgttcccctt
     3361 ccccatcctc ttccccaaat ctaccccagt gtactctcaa catcatgtat tcataaaaaa
     3421 tagctcatag gtacaattaa tgctgccatg tgagcatgag tgtgaccttt cactgcacca
     3481 tagaaatctt acgaggggcc acatctccaa agaagagtga ctctgtcttc tccagaaatt
     3541 accaactacc aatagctctt cagtaagggc taggaccaag aagcatcttt tatagtcagt
     3601 ttcttctatt agagtcctaa caagacttac atgtagcatc tggtatgctc ttaagtcttt
     3661 gataacaccc ttcctccttt actcagccca tgactggttg tataaattag agttctataa
     3721 aatgacctgt attctgaact tgtcttattg tttcctgttg ttatttctgt gttggctcta
     3781 tttcatattt cttggcttga tttgattgag actggatttg gggaaaaaat actttcttag
     3841 tacatcatat cacagggatc cttgggacac attggcccag attttctaga cttgtcagtg
     3901 ggtttagaat atctcaacct gagtactcca gttgtccttc ttcacccttg tcttttgttt
     3961 ttgttttttt gaggtagagt ctcataacac agggtactct taaattccct atgtcgaact
     4021 tctgatcttc ctgtctccac ttcccatgtt ctgggattat atgtgagtac cactatgctt
     4081 ggctcccctt ttggtcaccc tctcccttta agcaaaaaac atggctctca tatatttatc
     4141 ccctgttgct tcagtgaagc ctaggtcaat gggatgctca ggttggtcgc ttacttcttc
     4201 ctgcatcctc ctggatgaga gacagctctc gatgtggcct cttagaagac agtcatgcaa
     4261 gatgacatag ccagatctac caacacccgt gttgccactc attctgtctt ttccctccct
     4321 ggaaagttct tctgagatgc tactccagag cttagtggct gtcttattta gtctttacct
     4381 cttgggaact caataggtaa gtgccttcca cacaaatatg tattctgacc ttttgtaact
     4441 ggaatcaggg tcttccctgg aaatcattag cttaggtttg gttctgagtt catgatcttg
     4501 cgttagtttc ctgagtgcta gatgacagat gtgtgtcatc acaactggcc acattacggt
     4561 tttatgtatc agttccatgg cttccctcca tcagccagta tcaccgcatg aatgaaatga
     4621 tgtgacgatg gaaggatctt gctttctgaa ctctatgaac tctcaaaccg tagccaaatt
     4681 ctattctaat tacatctatt ctaccagggc tcagaagacc cactcttgct ctgatttttc
     4741 tctgtattag tcatgtgaat ttgttcaggc ctctctcact aaacctttct ataaccggga
     4801 gtaagatttt ttaaaaaaat gtggtcacca ttagcttctt ccagctgatc aattaagtga
     4861 caactaggaa atctttgtcc aaatgaaaga ccttgctatc cacagccaca cagtggcaga
     4921 ttcctgccaa gcagtgctgt gtcaggggat tccacaagat gatttcccac acactggaag
     4981 aaagttccaa gcagcagctt tgaaaggagt ccaggatgag ttgaaaaacc tgacatcctg
     5041 gatggtggtt cctgttacct gctaattaat atgtgagaga taacagctga gtttaccatc
     5101 cctaacccat ttatttcatt ttatttgggg cctgcacttt ctgtacgtcc catatatttt
     5161 aggttttacc tggctttcaa ataaatttct tgtaagttgt cctgcaaatg aaattactgt
     5221 ctggaaaact gcaatttcat cttgagagtt ttattatgct aataaatgtc agaattctca
     5281 aataaa
//
