LOCUS       NM_001105937            5116 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus small G protein signaling modulator 1 (Sgsm1),
            mRNA.
ACCESSION   NM_001105937 XM_001080492 XM_222270
VERSION     NM_001105937.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5116)
  AUTHORS   Zhang,Z., Wang,S., Shen,T., Chen,J. and Ding,J.
  TITLE     Crystal structure of the Rab9A-RUTBC2 RBD complex reveals the
            molecular basis for the binding specificity of Rab9A with RUTBC2
  JOURNAL   Structure 22 (10), 1408-1420 (2014)
   PUBMED   25220469
REFERENCE   2  (bases 1 to 5116)
  AUTHORS   Nottingham,R.M., Pusapati,G.V., Ganley,I.G., Barr,F.A.,
            Lambright,D.G. and Pfeffer,S.R.
  TITLE     RUTBC2 protein, a Rab9A effector and GTPase-activating protein for
            Rab36
  JOURNAL   J Biol Chem 287 (27), 22740-22748 (2012)
   PUBMED   22637480
REFERENCE   3  (bases 1 to 5116)
  AUTHORS   Luo,Y., Xing,F., Guiliano,R. and Federoff,H.J.
  TITLE     Identification of a novel nurr1-interacting protein
  JOURNAL   J Neurosci 28 (37), 9277-9286 (2008)
   PUBMED   18784308
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Oct 27, 2010 this sequence version replaced NM_001105937.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1580633.1,
                                           SRR26643298.81369.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                JAXUCZ010000012.1  48981729-48981774
            47-90               JAXUCZ010000012.1  48981857-48981900
            91-166              JAXUCZ010000012.1  48999958-49000033
            167-329             JAXUCZ010000012.1  49001855-49002017
            330-482             JAXUCZ010000012.1  49002431-49002583
            483-550             JAXUCZ010000012.1  49003624-49003691
            551-696             JAXUCZ010000012.1  49004009-49004154
            697-828             JAXUCZ010000012.1  49004286-49004417
            829-953             JAXUCZ010000012.1  49007387-49007511
            954-1021            JAXUCZ010000012.1  49009459-49009526
            1022-1185           JAXUCZ010000012.1  49010188-49010351
            1186-1318           JAXUCZ010000012.1  49010533-49010665
            1319-1457           JAXUCZ010000012.1  49014193-49014331
            1458-1522           JAXUCZ010000012.1  49015986-49016050
            1523-1668           JAXUCZ010000012.1  49016550-49016695
            1669-1797           JAXUCZ010000012.1  49020368-49020496
            1798-1980           JAXUCZ010000012.1  49022278-49022460
            1981-2049           JAXUCZ010000012.1  49023153-49023221
            2050-2637           JAXUCZ010000012.1  49025264-49025851
            2638-2762           JAXUCZ010000012.1  49029259-49029383
            2763-2845           JAXUCZ010000012.1  49031609-49031691
            2846-2955           JAXUCZ010000012.1  49034658-49034767
            2956-3052           JAXUCZ010000012.1  49036857-49036953
            3053-3220           JAXUCZ010000012.1  49039128-49039295
            3221-5116           JAXUCZ010000012.1  49045036-49046931
FEATURES             Location/Qualifiers
     source          1..5116
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..5116
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /note="small G protein signaling modulator 1"
                     /db_xref="GeneID:288743"
                     /db_xref="RGD:1308178"
     exon            1..46
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..3309
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /note="RUN and TBC1 domain containing 2"
                     /codon_start=1
                     /product="small G protein signaling modulator 1"
                     /protein_id="NP_001099407.2"
                     /db_xref="GeneID:288743"
                     /db_xref="RGD:1308178"
                     /translation="MASVPAEAETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIIS
                     FCAAVEACVLHGLRRRAAGFLRSNKIAALFMKVGKGFPPAEELSRKVQELEQLIESAR
                     NQIQGLQENVRKLPKLPNLSPLAIKHLWIRTALFERVLDKIVHYLVENSSKYYEKEAL
                     LMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHLRQDSPTK
                     RPALCIQKRHSSGSMDDRPSISARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAVPG
                     YLSLHQTADVMTLKWTPNQLMNGSVGDLDYEKSVYWDYAVTIRLEEIVYLHCHQQVDS
                     GGTVVLVSQDGIQRPPFRFPKGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPK
                     LRKRSPQGSSESTSSDKEDDEATDYVFRIIYPGTQSEFVPQDLMDVSMNNLPSLWQPS
                     PRKSSCSSCSQSGSADGSSTNGCNHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLST
                     VRTHLSALVNHMIVSPDLPCDAGQGLTASIWEQYIQDSTTYPEQELLRLIYYGGVQPE
                     IRRAVWPFLLGHYQFGMTEMERKEVDEQIHACYAQTMSEWLGCEAIVRQRERESHAAA
                     LAKCSSGASLDSHLHRMLHRDSTISNESSQSCSSGRQNLRLQSDSSSSTQVFESVDEV
                     EQTEAEGRSEEKHPKIPNGNPANGTCSPDSGHPSSHNFSSGLSEHSEPSLSTEDSVLD
                     VQRSLPAVFRPGDSSVEDGQSSEATTSRDEAPREELAVQDSLESDLLANESLEEFMSI
                     PGSLDVALPEKDGAMMDGWPGEADKHGRADSEDNLSEEPEMESLFPALASLAVTSSAN
                     NETSPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRSYWYFTAANLEKLRNIMCSYI
                     WQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMR
                     SLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAKHVSS
                     AHYVLFIALALVEVYRDIILENNMDFTDIIKFFNEMAERHNAKQILQLARDLVHKVQI
                     LIENK"
     exon            47..90
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            91..166
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            167..329
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            330..482
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            483..550
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            551..696
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            697..828
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            829..953
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1021
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1185
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1318
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1457
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1522
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1668
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1797
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1798..1980
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2049
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2637
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2638..2762
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2763..2845
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2846..2955
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2956..3052
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3053..3220
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3221..5116
                     /gene="Sgsm1"
                     /gene_synonym="Rutbc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcacccggt accgaccagc ttgagccatg gcttcggtcc ctgcggaggc cgagacccgc
       61 cagaggctgc tgcgcaccgt gaagaaggag gtgaagcaga tcatggagga ggctgttacc
      121 cgaaagttcg tccatgagga cagcagccac atcatctcct tctgcgcggc cgtggaggcc
      181 tgcgtgctgc atggactgcg gcggagggcg gccggcttcc tgcgaagcaa caagatcgcg
      241 gcgctcttca tgaaggtggg caagggcttc cctccggccg aggagctgag ccgcaaggtc
      301 caggagctgg agcaactcat tgagagcgcg cgaaaccaga tccagggcct gcaagagaac
      361 gtgcggaagc tgccgaagct acccaacctg tccccgctgg ccatcaagca cctgtggatc
      421 cgcaccgccc tgttcgagag ggtcctggac aaaatcgtcc actacctggt agaaaacagc
      481 agtaaatatt acgagaagga ggcgctcctg atggacccgg tggacggacc catccttgca
      541 tctttgttgg tggggccgtg tgccctagag tataccaaga tgaagactgc agaccacttc
      601 tggactgacc cctcagccga cgagctggtc cagagacacc ggatccacag ttcgcatctg
      661 agacaggatt cacccaccaa gcggccggcg ctctgtatcc agaagaggca ttccagcggc
      721 agcatggacg accgaccatc catatctgcc cgggactatg tagaatctct gcaccagaac
      781 tccagggcca ccctgctcta cggaaagaac aatgttctgg ttcagccaag ggatgacatg
      841 gaagccgtgc caggatacct gtctctgcac cagacagctg atgtcatgac cttgaagtgg
      901 acacccaatc agctgatgaa cgggtctgtg ggggacctgg actacgagaa gagtgtctac
      961 tgggactacg ctgtgaccat ccgcttagag gagatagttt acctgcactg ccaccaacaa
     1021 gtggacagcg gcgggaccgt cgtgctggtg agccaagatg gaatccagag gccgcccttc
     1081 cgcttcccca agggcgggca cctgctacaa ttcctctcct gtctggagaa tgggctgctt
     1141 ccgcatgggc agctggaccc gccgctttgg tcacagcgag gaaaggggaa ggtgtttcct
     1201 aagttgcgca agcggagtcc acaggggtcc tctgagtcca cgtcttcaga caaagaggat
     1261 gatgaagcca cagattacgt tttccgcatc atctaccccg gcacccagtc tgagttcgtg
     1321 ccccaggacc taatggacgt ctctatgaac aaccttccat ccctatggca acccagtcct
     1381 cggaagtcct cctgctcttc ctgttcacaa agcggctcag ctgacggcag ctcaaccaat
     1441 ggctgtaacc acgagagggc tccactgaaa ctgctctgtg ataacatgaa gtaccagatc
     1501 ctctccagag ccttctatgg atggctcgcc tactgcagac acctgtccac cgtgaggacc
     1561 cacctgtcag ccctggtcaa tcacatgatc gtgtctccag acctgccctg tgacgctggg
     1621 caagggttga cggccagcat ctgggagcag tacatccagg acagcacgac ttacccggag
     1681 caggagctgc tgcggctcat ctactatgga ggtgtccagc ctgagatccg cagggcagtg
     1741 tggcccttcc tcctgggcca ctaccagttt gggatgacag agatggagag gaaagaggtg
     1801 gacgagcaga tccacgcctg ctacgcacaa accatgtcgg agtggctggg ctgtgaagcc
     1861 atcgtgagac agagggagcg ggagtcccac gcggctgccc tggccaagtg ctcttccgga
     1921 gccagcctgg acagccacct tcaccggatg ctgcaccggg actctaccat cagcaatgag
     1981 tcctcccaga gctgcagctc aggccgccag aacctccgac tgcagagcga ttccagcagc
     2041 agcacacagg tatttgagtc agtggatgag gtggaacaga cagaggcaga aggcaggtca
     2101 gaagaaaaac accccaagat ccccaatggg aacccagcaa acggcacttg ctccccagac
     2161 tccggacacc cttcctccca caacttctcc tccggcctct cagagcactc agagcccagt
     2221 cttagcaccg aagacagtgt cttggatgtc cagcgcagcc tccccgctgt gtttcggcct
     2281 ggggacagca gtgtggaaga cggacagagc agcgaggcca ccacttcccg ggacgaggcc
     2341 ccccgggagg agctggcagt acaagacagt cttgagagtg acctccttgc caacgagagc
     2401 ttggaggagt tcatgtccat ccctggcagc ctggacgtgg ccctgcccga gaaggatggc
     2461 gccatgatgg acggctggcc tggcgaggca gacaagcacg gtcgggctga cagcgaggac
     2521 aacctctcag aggagccaga gatggagagt ctgttccctg ccctggcttc tctggctgtg
     2581 acctcctctg ccaacaacga gacgtcccct gtgtcctcca gtggcgtcac ctactctcca
     2641 gagctactgg acctgtacac ggtgaacctg caccgcatcg agaaagacgt gcagaggtgc
     2701 gaccgcagct actggtactt cacagccgcc aacctggaga agctgaggaa catcatgtgc
     2761 agctacatct ggcagcacat cgagattggc tatgtccagg gcatgtgtga cctcttggct
     2821 ccgctgttgg tcatcctgga tgacgaggcc ctagccttca gttgcttcac agaactcatg
     2881 aagaggatga accaaaactt cccccatgga ggcgccatgg acacacactt cgccaacatg
     2941 aggtctctga tccagatcct ggactctgag ctcttcgagc tgatgcatca gaacggcgac
     3001 tacacccact tctacttctg ctatcgctgg ttcctgctag atttcaaacg agaactggtc
     3061 tatgatgacg tcttctccgt gtgggagact atctgggcgg ctaagcacgt gtcctccgcc
     3121 cactacgtgc tgttcatcgc gctggcactg gtggaggtct accgagacat catcctggag
     3181 aacaatatgg acttcaccga catcatcaag ttcttcaatg aaatggccga gcggcacaat
     3241 gcaaagcaga ttctgcagct tgcccgggac ctcgtgcata aggtgcagat tctgattgag
     3301 aacaagtgaa gatctgctgt cgtccgcccc ctccctccct cctgcagccc agcacaaggc
     3361 cctggcgtct gtggaccagc gtggacctct gtgcagagag ccatgctctt atccttggcc
     3421 actgggcagt gagtggggta gagaagaacc catcttggcc ttacgttttt cctgtttgac
     3481 caaagagtgc ccaagtctgg gatttcccca cttcttggga gttgaggttg tgagtgggta
     3541 gaggtggcct ctggctctgt tcttcctttc ctgtttcttc ctcatctgta caggagaggc
     3601 ctttggggtt tcctctgcac ccagcaagga aggacctttg gaggtgttcc agaaccttcc
     3661 tgccagactg gcttgaagca ggctgtcccc ataggcattg ctcacattca gagtcccagg
     3721 tgttttcaag cgtcacccct gccttcaagc caccaggtct catcccccac ccccaatctc
     3781 ccgaggtgac tccgatgccc ccttatagtt tgtgtgcccc acccaagaac ctctggcttg
     3841 caggaggggc taccagcatg tctctgtgta tcctcactcg aggcctgttc tgtcgtgccc
     3901 ctggcagaag cttctgactc agccctgcct gagtccccga tctaacgatc taactccctg
     3961 tgtttccgac ttttctctct ccgctgccaa gagactctct taagaaaggg catctctctt
     4021 aagaaggtgc cctggagatc caggaagaga ttgcaggagc tcctgatgag agcccaaccc
     4081 ttcctgtccc acccccccgg ggagacatcc ccaccatcac tggtggtctg ggctcagaag
     4141 ccttcggact tggtaggagc catgctcagc aaggttgggt tttctctaag cactttgttc
     4201 actcaggaca gaggagggat gagcgagggg gttggcccat ggcagggttt gtctgtgttc
     4261 cttgatggag agcttggaac cagggctgga tctgaggaca ttccctcccc accttcacac
     4321 caagacctgc ttatccacac actgaccccc attgagcttt cgtacctgca tcctgggtgc
     4381 agcggaaatc aacactccta gtctaaactt gtccccagga tctgcagcct ctgggacaat
     4441 caagaaatgg cagggaggat tttatgagga gatatacatg gcttgaggta tcttcaggct
     4501 ggagccccac tctgtccgct tcctgtgacc tcccactccc acccccgccc cacctcccga
     4561 atcagatcct ctgtctcata tgcagggggc agggtggata gagagagcct tgtaatctcc
     4621 atggaagact gaggctgctt cggccccact tgtgcccagg gaggtggcca atgagcacag
     4681 tcaccggtgt agagttccat gcgccttcca gctaggtccc ccagcttccc aagatggggg
     4741 aagacaggcc gtcagataaa agtttatttt gccggtgcag aaggggtatt ttagcacagc
     4801 caggtccgga cctcctgacc cttatttatt tatttttata actgaccagc gtggagtata
     4861 gcacaagatt cccctccgcc tccctcgtgc ctcccgagcg tgcgcttgtg gttccgagtg
     4921 cctcgtattt attcaattta ccagccgatg acgtctgtgt gcagtgttcc ctggtgtcct
     4981 ggagttgggc atggggtggg gggagcggct tcctcctgcc caaggagttc tctttttaac
     5041 gttgcccaag tgtcttgtaa atgttctttg ccaagatgac tattcagagc aaatatatct
     5101 gagcagaaaa acataa
//
