LOCUS       XM_039087537            7191 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus N-sulfoglucosamine sulfohydrolase
            (Sgsh), transcript variant X1, mRNA.
ACCESSION   XM_039087537
VERSION     XM_039087537.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 9, 2024 this sequence was replaced by
            NM_001427070.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7191
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7191
                     /gene="Sgsh"
                     /note="N-sulfoglucosamine sulfohydrolase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 12 ESTs, 8 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     211 samples with support for all annotated introns"
                     /db_xref="GeneID:688293"
                     /db_xref="RGD:1591134"
     CDS             42..1550
                     /gene="Sgsh"
                     /codon_start=1
                     /product="N-sulphoglucosamine sulphohydrolase isoform X1"
                     /protein_id="XP_038943465.1"
                     /db_xref="GeneID:688293"
                     /db_xref="RGD:1591134"
                     /translation="MHRPAVACCLLLLVLGLYGAHSRNVLLIVADDGGFESGVYNNTA
                     INTPHLDALARHSLIFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFD
                     KVQSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAFTEENSSVLQVGRNITRIKQLVR
                     KFLQTQDDRPFFLYVALHDPHRCGHSQPQYGAFCEKFGNGESGMGRIPDWTPQIYDPQ
                     DVMVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLIIFTSDNGI
                     PFPSGRTNLYWPGTAEPLLVSSPEHPQRWGQVSDAYVSLLDLTPTILDWFSIPYPSYA
                     IFGSKTIQLTGRSLLPALEAEPPWATVFSSQSHHEVTMSYPMRSVYHQNFRLIHNLSF
                     KMPFPIDQDFYVSPTFQDLLNRTAAGQPTGWYKNLQHYYYRERWELYDISRDPRETRN
                     LAAEPDFAQVLEVLKAQLVKWQWETHDPWVCAPDGVLEEKLTPQCRPLHNEL"
ORIGIN      
        1 gaggggccga gccggaaccg ctcaccctga tcggcgccgc catgcaccgc ccggcagtgg
       61 cctgctgctt actgctgttg gtcctgggac tctacggcgc gcactcgcgc aacgtgctgc
      121 tgatagttgc tgatgatgga ggtttcgaga gtggtgtgta caacaacacc gccatcaaca
      181 cccctcacct ggatgccctg gcccgccaca gccttatctt ccgtaatgcc ttcacatctg
      241 tcagcagctg ttccccgagc cgtgccagtc tcctcacggg cctgccccag catcagaacg
      301 gcatgtacgg gctgcaccag gatgtacacc acttcaactc tttcgacaag gtacagagcc
      361 taccgctgct gctcagccag gccggagtgc gcacaggcat catcgggaag aagcatgtgg
      421 gcccggagac ggtgtatccc tttgacttcg cattcacaga ggagaacagc tcagtgctgc
      481 aggtggggcg gaacatcact agaattaagc aactcgtccg gaaatttctg cagactcagg
      541 atgacaggcc cttcttcctc tatgtggccc tccatgaccc ccaccgctgt gggcactccc
      601 agccccagta cggagccttc tgtgagaagt tcggcaacgg ggagagtggc atggggcgca
      661 ttccagactg gacaccccag atctatgatc ctcaggatgt gatggtgccc tactttgtcc
      721 cagacacgcc ggcagcccga gctgacctag ccgctcagta caccaccatt gggcggatgg
      781 atcaagggat aggattggtg ctccaggagc ttcgaggtgc cggtgtgctg aatgacaccc
      841 tcatcatctt cacatccgac aacgggatcc ccttccccag tggcaggacc aacctgtact
      901 ggcctggtac agctgagcca ctgttggtgt cctccccaga gcacccacaa cgctggggcc
      961 aagtcagcga cgcctacgtg agccttctag acctcacccc caccatcctg gactggttct
     1021 ccattccata ccccagctat gccatcttcg gctcaaagac gattcagctc acaggccgtt
     1081 ccctcctgcc ggcgctggag gcggagcccc cttgggccac tgtcttcagc agccagagcc
     1141 accacgaggt caccatgtcc taccccatgc gctccgtgta ccaccagaac ttccgcctca
     1201 ttcacaacct cagcttcaag atgccgtttc ccatcgacca agatttctac gtctcgccga
     1261 ccttccagga cctcctgaac cgcaccgcgg caggccagcc cacgggctgg tacaagaatc
     1321 tccaacatta ctactacagg gaacgctggg aactctatga catcagccgg gaccctcggg
     1381 agacacggaa cctggccgct gagccagact tcgctcaggt gctggaggtg ctgaaagctc
     1441 agctcgtcaa gtggcagtgg gagacgcatg acccctgggt gtgtgcccct gatggggtcc
     1501 tggaggaaaa gctcacgcct cagtgccgac ctcttcacaa tgagctctga cggtgcccgg
     1561 ggcacctgcc agcccaccta gacacgaagg gagggagcag tggaggcagt gccagcagct
     1621 gctccctcta cacacccatc cgagcaggtc cctccaccat atgggatgtc actcccgcct
     1681 cctgtggagg acactcaagc atgcactccc tagttgctgc cgttccaagg acactgctgt
     1741 cctcatgtcc gcctgtcctg gttcaggagt tctaggggaa tgtgggcatg gcagaacccc
     1801 acgttttgat aggtgagttt tgagagctac agacagaagg ggcagggtct ggggcttgaa
     1861 gccctctgct tccggaaacc tgcggatgtt tttaagcccc tcgccctaag aggatgccag
     1921 gtttctgcat gccacatgag cagtgggcag accgcactaa ctacttcaac caacttggcc
     1981 tggagggagc attcagtagg ccttgagctt gcttcgccac tgcccccccc ccccccgccc
     2041 gccccgttcc ccctttgaag tacacgctta gccaggattc atgctggtac tcagaggtgg
     2101 cgagttgatc ctatggtcta tctggtctca gtttgtgttt tctgagggtg gctgaggagg
     2161 acagggtgtg acagtgctct ctgtctgtct gtcttctctg ttcctgtctg tctctgtgtc
     2221 tctgtcccct cccctctctc cctgagtgac actaagcacc tggccccaga tttttccttc
     2281 tttcacttgc caagggacag aggcacagcc tagaaatcta gagaggcctg ttccctcctc
     2341 ccttctatca agatacccca tcttgggaga gaatgagagt catgggcccc agcattggga
     2401 aaaccttttt acaacagtat aatcattcac agaacatcgt aggagcacac tgggtctctg
     2461 gcaccgagac acaaacaccc tgtcaactga ctcagtttat ggctgggtgg gggcttcacc
     2521 caagtgtggc gtgatacatc ccgagaagga ccaggggata atgtcagttc aagaatgagt
     2581 tctttgctca caaagggttg gtcagttggc tccaggatat gtaccaaagc aacctggtgt
     2641 ttggggccgg gcacagagca gtgagtcaaa gagccgctca agtctgtcca ctacagcagc
     2701 ttcctttgct ggtgtctgtg gtagctgagt cagtcacgcc cacagcgctc cagtcagtgc
     2761 cccaccctgg gcggtgagga ttgctccagt gaccctccag ggttcacttg acatcggaaa
     2821 cataaaaaga gggacagacc cacgacctgg tcctgttacc acagaaggtt ggagtgctgg
     2881 ctctgagcag gtctcaggaa acacccccac atggccgaat attctccggt cctccatcag
     2941 cccaggccgt gctgtgggaa ggtgcttcat cattttcgcc ttgatttctg tgagcacctg
     3001 aggccagacc ctgaccagag aaggaagtag ggctgtttgc tgacggcatt aagagacaca
     3061 tggaggtccc cacagtccca ggccaggtgt gggcttcagc aggggccctc tgtccacacc
     3121 accttcttct gctcatccgc aatggccagg cgcacacagt tgagcaggct gtccagatca
     3181 ctccagttgt cgggggccag gctgctgtac agacagggca ctctgtccag ttccccctct
     3241 tcctgccggg ccacctccag gaactgctcc tctgagctgc caagccgatg taggcctttc
     3301 ctgcaaagca gagagatgtt cagctcgagg acagcaaggt aggcaggaag tacacagttg
     3361 gctttagtac ggggcactgt aggcatccag gccagaacct tgggcatgaa catgggggtc
     3421 ctatctagga aagctcatga aggtcctacg acttggctgc aagcagcatt cacttcccag
     3481 aggatacggg cagcgggatg tttgtcctgg gtatgggcag tgggatgttt gtcccagcca
     3541 gacaagtgat agaatgggac taggcttcat gagccgcagg cacatgtgcc cctttagtgt
     3601 agccgggaca gggaacaggt tcgttcaccc ctgagggaga gcaagctgga cctctggccc
     3661 gaggttgcaa ggacgtgact ggggtggaac ttagagaact ttagtgtgtt cccgaggcat
     3721 tcgacaagct tttccagagc acaagcacct gtttagaccc tgctgcccag ttcctaccac
     3781 caagcaacta cctgagtttc tttgccgtct tctcattgac agaaacgtgg atgatgatgg
     3841 gaaatatgtc catcttgtgt aagactcgga cgctgtccag ccggacatcc agcagggcat
     3901 gggtgctctt tagaagggca tagagaagca agttaagccc ctgggcctcg ggtctgggag
     3961 gaagtgggag gagactgcag cagagcacag ggctgtgtgg agagacctga atagaggctg
     4021 cgtggcaggg cctgccgtag atctcaaagg caaaccattt ggtttgtccc tgaggaaatt
     4081 gggatttgca agcctttggc attgaggcag attttgcata gagtccaaac cgtacgaatc
     4141 agacagtacc actaactgtt ggcctgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     4201 tgtgtgtgtg tgtgttgtcc ttcctactcc ttatggaagt gtgaaactcg acagtttact
     4261 gagagctgta aaatgtgaga cttaatgtct ccatttattt catttattaa caaagatcta
     4321 tcaaacaagt taagggaact gaggcccaaa ggcccaccca agggcggtcc agcatcatca
     4381 catggatccc agatggtagg aacaggcttg gatctttctg catccctcct acagagaatg
     4441 aagctgggtg tctagggccc cacaagtgac tccccaaccc tgggcaggag ctgccacccc
     4501 cagagtagcc tctagaccct ccccttaccg tattcatgag ggactgcacg gcatgccggg
     4561 tgacacagtg gtggtcacct attgactctc cctcctggat gatgtcccct ctctgactcc
     4621 aggtgacata ctcctcctgg ctcaagtact ctgatggtga cattagatga ggtggtcata
     4681 cattgggatc ctgaggaagc caagctgagc attccatact ggaggtctcc tgccacatcc
     4741 aagagaagct tcccatggtg gtcacataga gtcctatacc acctttgacc acaagtcctc
     4801 tggtacaccc accccagggc atggcaatgt gtgaactctg ggtagtgttt tgggcagcgc
     4861 tctctctctc tctctctctc gcgctctctc tctctctctc tctctgtgtg tgtgtgtgtg
     4921 tgtgtgtgtg tgtgtgtgtg taagtggccc tgccaaacat cctacagtgc tcaggacagc
     4981 tacccaatag agaatgtcag ccacaggtgt cctggtgccg aggttgagaa ccattctgga
     5041 gtcctcttga acaggctctt acgccccatc ttggtcagaa ggaccctgtc ttcctcctag
     5101 ctatcaaagc accccagctg tacatgtccc ccttccccac catcactgca gcatcgatgg
     5161 gaaccctaga cccaagttcc agcgagcgca tccccaaccc tggcctggcc tcctgtctct
     5221 cactctgctg ggaatcacac gaagcagtga gccctccctc cccgtaaaga ctcaggcttt
     5281 tatgaaactg gacatgtggc ctccgctctc cttggccacc acagcagtgg ctcaagccca
     5341 gggttctggg ttcccttgtg cctttgtatg cacccactgg ccagccggat cacctcgcca
     5401 cctccagcta ccacccatct tccttctgca ccctgtcagc tagccttcat gtatgtgttc
     5461 ccctccctct ttgggtaagt gtggagcccc acagcctgta tagctttacc ccactggttt
     5521 gcccaactga acccaggcgg ccaattctag agaactcatg ggctcccaga ctcagtttct
     5581 tccactttcc catggacgct agccaagaaa ggtgctcatc agagcagcct catgggtggt
     5641 acctgtttct ttctctctag gatgaactct ctcagccaac agggcaggta acctagccct
     5701 gtcagccttt cctgagccca cgggcctggg gatcagagag cactttcatg aagcctccat
     5761 gtcggatctc tgagctcaag gctggcctgg tctacagagt gagttctagg acagccaggg
     5821 ccatacagag aaaccttgtc tcaaaaacct ctaagtaaat aaagagaagc tgcctgtggc
     5881 tgatggacag agcccttgag ccatgatacc gtgctaacta catctgtttt caacgtgcct
     5941 gtgttggagg gagaggtagt gacccacctc tctcgtgccc gtaagaaccc agaatggact
     6001 ttctatggaa agagggcctc tgtgtgaggc aacactgggt tacgatagac cctaagaagg
     6061 ccatgtgtag acaaagacac agaaggaaaa gggcagcgat gaccaacgcc aagatgggag
     6121 tggggacttc ccgaatgcct aagggactga aagaaccagg aaggacccac agcttgcagc
     6181 ccccagagaa cagggccctg ctgaggccct gaggtcagaa atcccaggaa ccataagaca
     6241 gttcagtgtt ccagtttgtg gccctttgtt atagtgtgtg gtggtttgca tatgcctggc
     6301 ccagggagtg gcaccgttag aaagtgtggc cttattggag gaagtgtgtc actggagtgg
     6361 ggcttggaga ccctcctcct agctgcctgg ggatgcttaa tctgttcttg gcttcctcct
     6421 ggtgaagttg tagaactgag ctcttcctgc accatgcctg tctggatgct gccatgctcc
     6481 cgccttgata atggactgaa cctctgaacc tgtaagccag ccccagttaa atgttgttct
     6541 ttataaaact tacattggtc atggtgtctg ttcacagcaa tcagacccta agtaagacac
     6601 ggtatctctg aatttagggt cacctgctct ggccactcac tcaacgggga agcacatacc
     6661 tgctgaacac tgcttaaaac cttggaggag acacagcttt ttgcccagga tcttcccaat
     6721 tactctgggc acgaacagca caggccgggg ccacgcaggc ctatgggggt gcaccagggt
     6781 gtaaggtgcc agggtaaagc agttttctgg ccagaagcac acgctgggac cacctgtcga
     6841 ggacagaggt tatgaacacc tcccacctgt gtccctgacc cctctctccc cggagagccg
     6901 gatgggggac attctcagct tcgatgctgc cgactgtgtg tgctggctca gctgctccag
     6961 agctcacagc tcttcaggac gagcctctga ggaccggagg agcctggttc ctcctgaagg
     7021 gtataagggg ccctgccttt cgcccccacg ctccttctcc tcatcctcac cttctgttca
     7081 gccctgcccc tcagacctca gggtcctcag tctcctccct cctgggccct gggttatttg
     7141 ggttactcct gttttccata tcaaccttat tttctaaaag attttatttt a
//
