LOCUS       NM_022948               2699 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus sideroflexin 3 (Sfxn3), mRNA.
ACCESSION   NM_022948
VERSION     NM_022948.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2699)
  AUTHORS   Rivell,A., Petralia,R.S., Wang,Y.X., Mattson,M.P. and Yao,P.J.
  TITLE     Sideroflexin 3 is a Mitochondrial Protein Enriched in Neurons
  JOURNAL   Neuromolecular Med 21 (3), 314-321 (2019)
   PUBMED   31177362
  REMARK    GeneRIF: Sideroflexin 3 is a Mitochondrial Protein Enriched in
            Neurons.
REFERENCE   2  (bases 1 to 2699)
  AUTHORS   Kory,N., Wyant,G.A., Prakash,G., Uit de Bos,J., Bottanelli,F.,
            Pacold,M.E., Chan,S.H., Lewis,C.A., Wang,T., Keys,H.R., Guo,Y.E.
            and Sabatini,D.M.
  TITLE     SFXN1 is a mitochondrial serine transporter required for one-carbon
            metabolism
  JOURNAL   Science 362 (6416) (2018)
   PUBMED   30442778
REFERENCE   3  (bases 1 to 2699)
  AUTHORS   Yoshikumi,Y., Mashima,H., Ueda,N., Ohno,H., Suzuki,J., Tanaka,S.,
            Hayashi,M., Sekine,N., Ohnishi,H., Yasuda,H., Iiri,T., Omata,M.,
            Fujita,T. and Kojima,I.
  TITLE     Roles of CTPL/Sfxn3 and Sfxn family members in pancreatic islet
  JOURNAL   J Cell Biochem 95 (6), 1157-1168 (2005)
   PUBMED   15864810
  REMARK    GeneRIF: citrate transporter protein-like protein/Sfxn3 and some
            other family members might be important in the differentiation of
            pancreatic beta-cells
REFERENCE   4  (bases 1 to 2699)
  AUTHORS   Miyake,S., Yamashita,T., Taniguchi,M., Tamatani,M., Sato,K.,
            Kawai,Y., Senba,E., Mitsuda,N., Hori,O., Yamaguchi,A. and
            Tohyama,M.
  TITLE     Expression of mitochondrial tricarboxylate carrier TCC mRNA and
            protein in the rat brain
  JOURNAL   Brain Res Mol Brain Res 100 (1-2), 67-73 (2002)
   PUBMED   12008022
  REMARK    GeneRIF: TCC protein as well as mRNA was widely expressed in brain,
            and the protein expression was strong in neuronal cells in the
            hippocampus, the olfactory bulb, the corpus mamillare and the
            cerebellum.
REFERENCE   5  (bases 1 to 2699)
  AUTHORS   Baldo Sierra,C., Suarez Nieto,C., Llorente Pendas,J.L. and Bernardo
            Corte,M.J.
  TITLE     [Primary tumors of the external auditory canal]
  JOURNAL   Acta Otorrinolaringol Esp 43 (6), 439-442 (1992)
   PUBMED   1299286
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF276997.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF276997.1, BC062043.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2699
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..2699
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /note="sideroflexin 3"
                     /db_xref="GeneID:65042"
                     /db_xref="RGD:620716"
     exon            1..229
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            230..393
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..1198
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /note="tricarboxylate carrier-like protein; solute carrier
                     family 64 member 3"
                     /codon_start=1
                     /product="sideroflexin-3"
                     /protein_id="NP_075237.1"
                     /db_xref="GeneID:65042"
                     /db_xref="RGD:620716"
                     /translation="MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGKQLE
                     ASRNIVQNYRAGVVTPGLTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTI
                     TGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVAT
                     ALGLKSLTKHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSV
                     TAAKQGIFQVVVSRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLV
                     FATPLCCALFPQRSSIHVTRLEPELRAQIQAQKPSIDVVYYNKGL"
     exon            394..564
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            565..663
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            664..739
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            740..825
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            826..953
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1003
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1053
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1101
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..2681
                     /gene="Sfxn3"
                     /gene_synonym="SLC64A3; TCC"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcgggtctgg tctcaacagc ctggtctggg ggagtcactc cagatgacat ccactgtccc
       61 ggaactctgc caagaggggg gtgggtcagg cgaaccagtt tagggagccc ccgcccttcc
      121 ctgctgctca gcgtcacgcg tgacgtccgg gtgatggctg ggaggaaagc ggagagctgt
      181 gaggaaggcg ggtctgagag ctgctagagg ctgtaaatcc ccggaaagca agatgggcga
      241 cttgccctta aatatcaaca tccaggaacc tcgatgggac caaagcacat tcctaggcag
      301 agcccggcac ttcttcacag ttactgatcc ccgaaatctc ctgctgtccg ggaaacagtt
      361 ggaagcttct cggaacatcg tgcagaatta cagggctggt gtggtaactc ctgggctcac
      421 tgaggaccag ctatggagag ccaaatacgt gtatgactca gcattccacc cggacacagg
      481 ggagaaggtg gtcttgattg gtcgcatgtc ggcccaggtg cccatgaaca tgaccattac
      541 tggctgcatg ctcaccttct acaggaagac tccaactgtg gtgttctggc agtgggtgaa
      601 tcagtccttc aatgctattg tgaattactc taatcgcagt ggagacgctc ctatcactgt
      661 gcagcagctg ggaacggcct atgtgagtgc caccactggg gctgtggcta ctgctctggg
      721 actcaagtct ctcaccaagc acctaccccc actagtgggt cgattcgtac cctttgcagc
      781 tgtggctgcc gccaactgca tcaacatccc cctgatgagg cagagggagc tgcaggtggg
      841 catcccagtg actgatgaag ctggtcagag acttggccac tcggtgactg ctgccaaaca
      901 gggcatcttc caggtggtgg tatcgagaat cggcatggcg atccccgcca tggccattcc
      961 cccggtgatc atgaacactc tggagaagaa agacttcctc aagcgccgcc cctggctggg
     1021 ggcccccctg caggtgggac tggtaggctt ctgcttggta tttgccacac ctctgtgctg
     1081 cgctcttttt ccccagagaa gctctataca tgtgaccagg ctggagccgg agctgagagc
     1141 tcagatccaa gcacaaaaac ccagcatcga tgtggtttac tacaacaagg ggctttgagg
     1201 ggaatcggcc tctgtccctg tccttacctc cttaggctgc ttctttggtg ccacttctca
     1261 atgctaccac ctgtttaatc ttccgggtac tgggcagggg ggcttgatgt ggggagcagc
     1321 cactgagacc agcaacctta gactggggga ggcaccccta taagcctctt ctctcctctc
     1381 tggtttcaaa gagcaagtca caaagcccat ccctcctgtg tctgtgtgcg tgcgtgcaga
     1441 catacctagg cagtgcatgg aactgttcgt tcatttgctc ctgaatgcta aggcagaagt
     1501 gctgttctag gatgtcctga tgtttgtctt ctctctcggt ctcctgccca cctcacagca
     1561 agccaggtga taggcgagaa tcctttccct aagctattcc tctggccaag tcatttctga
     1621 tagcatctta gccttctgac cccaagataa gcgccaggat cccagaacac agactgaagg
     1681 acatctgcag atcttaaccc ttccagtttt gaatagctgg ctctgaaagc tggttcagga
     1741 gctgggctgg cagaggaagc agggtgggat cagggaagca gggggctcat acttgctgga
     1801 ctccacatcc tgggatggct ccactcctct cttctcttcc tatggaacat gaggatgtct
     1861 ctgtagcctg cagtgcccct accctgcttt tagagatagt cttgggcatt cttggtctgt
     1921 tctgatgact catgtcatga ctcagaaaga aatcccacaa tcccaattcc ttccccaatt
     1981 agaaagccac acaggcagag caagcattct cttcaggaac tgccaccccc tgtacccact
     2041 tataggggga ccggtgtggg aacggtgctt aaacacaggc ctcaagcgta caatatcaag
     2101 acaggtaatt ctgtgtttca ttgactcctc ttagacacac ccacctcagc tccttccttt
     2161 ccatctaccc cgtctctgaa agaacccagg gcttcacaat gctaggcaag tgctctacca
     2221 ctgagctaca tccccagtgc cccctcttcc ttccttcctg tctctttctt tcttttttgt
     2281 ttttgttttt caaatatggt ttctctatgt agccctggct gtcctggaac tcagagatct
     2341 gattgcctaa gacagtgagt tctgggatta aaggcatata ccaccattgc cagcagccct
     2401 tcttgttcct aagacatgga tggccctgtg ctccctctgc ccttcaaaaa gaggagggac
     2461 ccaggccttc atagctggac caaatggaag atgggtttag gaatggcatg agtggtaatg
     2521 actccagtgt gtagaattat atctgcactc taaatccatg acctctagct aaaaggcgaa
     2581 tggggtcccc agtgatatcc acggagacca ctttcactca ccccctcctc cagtgacaac
     2641 aggtgtcatg tcatggtgtc aataaactgc agtcctgtct aaaaaaaaaa aaaaaaaaa
//
