LOCUS       NM_001166020             359 bp    mRNA    linear   ROD 08-MAR-2024
DEFINITION  Rattus norvegicus surfactant associated 2 (Sfta2), mRNA.
ACCESSION   NM_001166020
VERSION     NM_001166020.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Krause,M., Peukert,N., Hartig,W., Emmer,A., Mahr,C.V., Richter,C.,
            Dieckow,J., Puchta,J., Pirlich,M., Hoffmann,K.T., Nestler,U. and
            Schob,S.
  TITLE     Localization, Occurrence, and CSF Changes of SP-G, a New Surface
            Active Protein with Assumable Immunoregulatory Functions in the CNS
  JOURNAL   Mol Neurobiol 56 (4), 2433-2439 (2019)
   PUBMED   30032421
  REMARK    GeneRIF: SP-G is a potential new cerebrospinal fluid (CSF)
            biomarker, possibly not only reflecting aspects of CNS innate
            immune responses, but also rheo-dynamically relevant changes of CSF
            composition.
REFERENCE   2  (bases 1 to 359)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX883047.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BF521842.1, AI136523.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                BX883047.1         229832-229908
            78-169              BX883047.1         230118-230209
            170-359             BX883047.1         230368-230557
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..359
                     /gene="Sfta2"
                     /gene_synonym="E030032D13Rik"
                     /note="surfactant associated 2"
                     /db_xref="GeneID:415052"
                     /db_xref="RGD:1303180"
     exon            1..77
                     /gene="Sfta2"
                     /gene_synonym="E030032D13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..256
                     /gene="Sfta2"
                     /gene_synonym="E030032D13Rik"
                     /note="surfactant associated protein G;
                     surfactant-associated protein 2"
                     /codon_start=1
                     /product="surfactant-associated protein 2 precursor"
                     /protein_id="NP_001159492.1"
                     /db_xref="GeneID:415052"
                     /db_xref="RGD:1303180"
                     /translation="MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGF
                     LDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA"
     exon            78..169
                     /gene="Sfta2"
                     /gene_synonym="E030032D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            170..359
                     /gene="Sfta2"
                     /gene_synonym="E030032D13Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaagtgag gcggccacca tggagccttc gatgtgcctc ttcctcctcc tgaccctcct
       61 ctgcagctca ctcgcagggc caacaaaggt gactttgcaa gtaaaactga ccgaggcatc
      121 tcaggccaag acctcccaag actccggctt tctggacatg ctccaaaaga tctgcctcct
      181 cctccacctc tcaccgggga ccaatgtcac ccttcatcat aaagggccac cacaccacct
      241 tacctgcaga gcctgagagc agctgaagcc tgcgtgggcc tggagcggtc agcctttggg
      301 gagtgagcat gccttggacc tagcaggccc ttgtcccgct gcaggctaat aaacgtgga
//
