LOCUS       NM_001400984            3386 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus splicing factor SWAP (Sfswap), transcript variant
            1, mRNA.
ACCESSION   NM_001400984 XM_039089423
VERSION     NM_001400984.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3386)
  AUTHORS   Wang,J., Gao,Q.S., Wang,Y., Lafyatis,R., Stamm,S. and Andreadis,A.
  TITLE     Tau exon 10, whose missplicing causes frontotemporal dementia, is
            regulated by an intricate interplay of cis elements and trans
            factors
  JOURNAL   J Neurochem 88 (5), 1078-1090 (2004)
   PUBMED   15009664
REFERENCE   2  (bases 1 to 3386)
  AUTHORS   Sarkissian,M., Winne,A. and Lafyatis,R.
  TITLE     The mammalian homolog of suppressor-of-white-apricot regulates
            alternative mRNA splicing of CD45 exon 4 and fibronectin IIICS
  JOURNAL   J Biol Chem 271 (49), 31106-31114 (1996)
   PUBMED   8940107
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Feb 1, 2022 this sequence version replaced XM_039089423.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-377               JAXUCZ010000012.1  32815656-32816032   c
            378-547             JAXUCZ010000012.1  32813107-32813276   c
            548-679             JAXUCZ010000012.1  32812363-32812494   c
            680-765             JAXUCZ010000012.1  32810018-32810103   c
            766-991             JAXUCZ010000012.1  32802757-32802982   c
            992-1104            JAXUCZ010000012.1  32800805-32800917   c
            1105-1240           JAXUCZ010000012.1  32799590-32799725   c
            1241-1481           JAXUCZ010000012.1  32775692-32775932   c
            1482-1610           JAXUCZ010000012.1  32774122-32774250   c
            1611-1704           JAXUCZ010000012.1  32773479-32773572   c
            1705-1786           JAXUCZ010000012.1  32772530-32772611   c
            1787-2017           JAXUCZ010000012.1  32766864-32767094   c
            2018-2208           JAXUCZ010000012.1  32765609-32765799   c
            2209-2474           JAXUCZ010000012.1  32761863-32762128   c
            2475-2627           JAXUCZ010000012.1  32757122-32757274   c
            2628-2753           JAXUCZ010000012.1  32755989-32756114   c
            2754-2927           JAXUCZ010000012.1  32747251-32747424   c
            2928-3000           JAXUCZ010000012.1  32746585-32746657   c
            3001-3386           JAXUCZ010000012.1  32745704-32746089   c
FEATURES             Location/Qualifiers
     source          1..3386
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q13"
     gene            1..3386
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /note="splicing factor SWAP"
                     /db_xref="GeneID:304431"
                     /db_xref="RGD:1305004"
     exon            1..377
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..3066
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /note="isoform 1 is encoded by transcript variant 1;
                     splicing factor, arginine/serine-rich 8
                     (suppressor-of-white-apricot homolog, Drosophila);
                     serine/arginine-rich splicing factor 8; splicing factor
                     SWAP homolog; suppressor of white apricot protein homolog;
                     splicing factor, suppressor of white-apricot family;
                     splicing factor, suppressor of white-apricot homolog"
                     /codon_start=1
                     /product="splicing factor, suppressor of white-apricot
                     homolog isoform 1"
                     /protein_id="NP_001387913.1"
                     /db_xref="GeneID:304431"
                     /db_xref="RGD:1305004"
                     /translation="MYGAGGGRAKAERKGGVKEEAGPGGTGTGGNRVELLVFGYACKL
                     FRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSAYDAEYATWNRDYQLSEE
                     EARVEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGNYSAVGFTYGSDYYDP
                     SEPTEEEEPSKQREKSEAENLEENEEPFIAPLGLSVPSDVELPPTAKMHAIIERTANF
                     VCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAESKSEEK
                     KKSGPTSDNEEEDDEEDGSYLHPSLFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQ
                     ADSSAPAPPTADGTPAQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVATY
                     YSTLPAGVTVSSSPGVTTTVPPPPGTTPPPPPTTAESSSGVTSTTTTTSALAPVAIIP
                     PPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQK
                     EGGGSTQAASTAEEAPTETAVEESSEAGEDGAPEASFAPISFAIKAKENDLLPLEKNR
                     VKLDDDSEEDEESRECQESTSSVANPSPAAAPPSAVVEEKKPQLTQEELEAKQAKQKL
                     EDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPDAEVGKLEESTFGV
                     EETGVMPCPLLVGGRTLPMLEGKPPERPSSRCRDPPREEEREKKKKKHKKRSRTRSRS
                     PKYHSSSKPRSRSHSKAKHSLPSAYRTVRRSRPSASPGILSVEPCPSSSAVAAAQQES
                     YQAASASSSFDSWSSFEGKPGKPSRSRSRSPRRRAHSPERRREDRSVPTAYRMSGSPG
                     VSRKRTRSRSPHEKKKKRRSRSRTKAKARSQSTSPSKQAAQRPSAHSAHSASISPVES
                     RGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS"
     exon            378..547
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            548..679
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            680..765
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            766..991
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1104
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1240
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1481
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1610
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1704
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1705..1786
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..2017
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            2018..2208
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            2209..2474
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            2475..2627
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            2628..2753
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            2754..2927
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            2928..3000
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            3001..3386
                     /gene="Sfswap"
                     /gene_synonym="Sfrs8; Srsf8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggaagttg cgtttcctcc attttgtggc tcgctatggc ggctgtgttg aagttacgaa
       61 gaggatgcgg cgcctttgac tgagagggta ggccaggcga ggcatcaggg acgttgttcg
      121 gcacagcagc agaccggccc ggacgtcgtg gacgctgtca tgtacggtgc cggcgggggc
      181 cgcgccaagg cggagaggaa aggcggagtg aaggaggagg ccgggcccgg tggcaccggc
      241 actgggggca accgggtgga gcttctggtt ttcggctatg cctgcaagtt gttccgcgac
      301 gacgagcggg ctttggccca agaacaggga cagcacctca tcccctggat gggggaccac
      361 aagatcctca tcgacagata cgacgggcgt ggtcacctgc atgacctctc cgcctacgat
      421 gctgagtacg ccacgtggaa ccgagactac cagctgtctg aagaggaggc gcgggtagag
      481 gcgctgtgtg atgaagagag gtatttagcc ttgcatacgg acttgcttga ggaggaggca
      541 aggcaagagg aagaatacaa aagattgagt gaagcgctgg cggaggatgg gaactacagt
      601 gccgtagggt tcacttacgg cagtgactat tacgacccgt cagagcccac agaggaggag
      661 gagccctcga agcagagaga aaaaagtgag gctgaaaact tggaagaaaa tgaggagcct
      721 ttcatcgccc ctttaggact aagcgtcccg tctgacgtgg agctgccacc aacagccaaa
      781 atgcatgcca tcatcgagcg cacagccaac ttcgtatgca agcagggagc acagttcgag
      841 atcatgctga aggccaagca agcacggaac tcacagttcg acttcctgcg gtttgatcac
      901 tacctcaacc cctactacaa gttcatccag aaagccatga aggaaggacg gtacacggtg
      961 ctagctgaga gcaagagcga ggagaagaaa aagtctgggc caacctccga caatgaagag
     1021 gaagatgatg aggaagatgg gagttacctg cacccgtctc tctttgcttc caagaagagc
     1081 agccgcctgg aagagctgat gaagcccttg aaggtggtag acccggatca ccctctagca
     1141 gcccttgtcc ggaaagcaca ggctgacagc tcagccccgg ccccacccac tgcagatggc
     1201 actcctgctc agccctccca ggtggagtac acggcagact caaccgtggc agccatgtac
     1261 tacagctact acatgctgcc agatggcacc tactgcctgg caccaccccc acccgggatc
     1321 gatgtggcta cttactacag cacccttcct gctggggtga ctgtgtccag ctcacctggt
     1381 gtgaccacga ctgtaccacc acctcctggg accacacctc ctccaccccc aaccacagct
     1441 gagtcaagca gcggggttac ctccacaacc accaccacaa gtgcgcttgc tcccgtggcc
     1501 atcatacccc cgccccctga catccagcct gtgattgaca agctggcaga gtacgtcgcc
     1561 agaaacggcc ttaaatttga gaccagtgtt cgagccaaga acgatcagag atttgaattc
     1621 cttcaaccct ggcaccagta caacgcctac tacgagttta agaagcagtt cttcctgcag
     1681 aaggaaggag gcggtagcac acaggcagca tcaacagctg aagaggctcc cacagaaacc
     1741 gctgttgaag agtcaagtga agctggagag gacggcgctc ctgaggcttc ttttgctcca
     1801 ataagctttg ccatcaaagc caaagaaaat gacctacttc ccctggaaaa aaaccgcgtc
     1861 aagctggacg atgatagtga ggaagatgag gaaagcaggg agtgccagga aagcacaagc
     1921 agtgtggcca accccagccc agccgcagcc cctccctctg cagtggtgga ggagaagaaa
     1981 ccgcagctta cccaagagga gctcgaagct aagcaagcaa aacaaaagct ggaggaccgc
     2041 cttgctgctg ccgcccggga aaagctagct caggcgtcca aggagtcgaa ggagaagcag
     2101 cttcaggctg aacggaagag gaaagctgct ttgtttctgc agaccttaaa aaaccctctt
     2161 ccagatgcag aagttggaaa acttgaggag agcactttcg gagttgagga aactggtgtc
     2221 atgccctgtc ctctgctggt tggaggtaga accctgccca tgttggaagg gaagcctcca
     2281 gaaaggcctt caagtagatg cagagaccca ccaagagaag aagaaagaga gaagaagaag
     2341 aagaagcaca aaaaacggtc tcgaacgagg tcccgctccc ccaagtacca ctcgtcttcc
     2401 aagcccaggt ctagatccca ctcaaaagca aagcactccc tgcccagtgc ctaccggaca
     2461 gtgcggcggt cgaggccctc agcctcccca gggatcttga gtgtggagcc ttgtcccagc
     2521 agctcggcag tggcggcagc acagcaggag agttatcagg cagcctcggc ctcgagcagc
     2581 tttgactcct ggagctcttt tgaggggaaa cctggtaaac cgtcaaggtc acggtctcgg
     2641 tccccaagaa ggagagctca ctctccagag agacgacggg aagacaggag tgtccccaca
     2701 gcctaccgga tgagcggcag ccctggagtc agcaggaaac ggacccgttc cagaagtccc
     2761 catgagaaga agaagaaacg gcgctcacgc tctcgcacca aggccaaggc ccggtcgcag
     2821 tcaacttccc cgagtaaaca ggcagcacag cgtccctcgg cccactcagc ccactcggcc
     2881 agcatctctc ctgtggagag ccgaggttcc tcccaggaac gatccagggg ggtttctcag
     2941 gaaaaagatg gccagatctc ctcagcaatc gtctcctctg tgcagagcaa aataactcag
     3001 gatctcatgg ccaaagtaag agcaatgctc gcagcttcaa aaaacctgca gaccagcgcg
     3061 tcctgagagg gcagccacgg agccagcccc tggcgagcag catggctgtg gccctggctg
     3121 tggctacagg tgctgggcta ctgctcagag cagccacagt ccagaagtca gaagctgagc
     3181 tgcaagctct gtgccgacct ccatgcggct ctccaggttc tccagcccaa ctccctgggt
     3241 cagtcggtgg cttttgtaaa tttttggtga cattttctgt ttcagatttt tgaccagcag
     3301 tctcttacct gtatatatgt aaatatatca tgtttctgtg aaaatgtatt atcaaataaa
     3361 atgggaaaca ccttttctag ctagca
//
