LOCUS       NM_001107364            5756 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus Scm-like with four mbt domains 2 (Sfmbt2), mRNA.
ACCESSION   NM_001107364 XM_001069730 XM_225556
VERSION     NM_001107364.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5756)
  AUTHORS   Lee,K., Na,W., Maeng,J.H., Wu,H. and Ju,B.G.
  TITLE     Regulation of DU145 prostate cancer cell growth by Scm-like with
            four mbt domains 2
  JOURNAL   J Biosci 38 (1), 105-112 (2013)
   PUBMED   23385818
REFERENCE   2  (bases 1 to 5756)
  AUTHORS   Lehnert,S., Kapitonov,V., Thilakarathne,P.J. and Schuit,F.C.
  TITLE     Modeling the asymmetric evolution of a mouse and rat-specific
            microRNA gene cluster intron 10 of the Sfmbt2 gene
  JOURNAL   BMC Genomics 12, 257 (2011)
   PUBMED   21605348
  REMARK    GeneRIF: a large miRNA gene cluster in intron 10 of the Sfmbt2 gene
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Apr 6, 2021 this sequence version replaced NM_001107364.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760386
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                JAXUCZ010000017.1  73032074-73032172   c
            100-231             JAXUCZ010000017.1  73020310-73020441   c
            232-326             JAXUCZ010000017.1  73011772-73011866   c
            327-567             JAXUCZ010000017.1  73009280-73009520   c
            568-656             JAXUCZ010000017.1  72979029-72979117   c
            657-903             JAXUCZ010000017.1  72976978-72977224   c
            904-1001            JAXUCZ010000017.1  72971257-72971354   c
            1002-1103           JAXUCZ010000017.1  72959342-72959443   c
            1104-1251           JAXUCZ010000017.1  72955576-72955723   c
            1252-1334           JAXUCZ010000017.1  72892833-72892915   c
            1335-1458           JAXUCZ010000017.1  72886937-72887060   c
            1459-1572           JAXUCZ010000017.1  72880364-72880477   c
            1573-1615           JAXUCZ010000017.1  72876670-72876712   c
            1616-1686           JAXUCZ010000017.1  72874843-72874913   c
            1687-1829           JAXUCZ010000017.1  72872216-72872358   c
            1830-1939           JAXUCZ010000017.1  72861927-72862036   c
            1940-2115           JAXUCZ010000017.1  72857591-72857766   c
            2116-2279           JAXUCZ010000017.1  72855635-72855798   c
            2280-2537           JAXUCZ010000017.1  72854343-72854600   c
            2538-2666           JAXUCZ010000017.1  72853094-72853222   c
            2667-5756           JAXUCZ010000017.1  72845696-72848785   c
FEATURES             Location/Qualifiers
     source          1..5756
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.3"
     gene            1..5756
                     /gene="Sfmbt2"
                     /note="Scm-like with four mbt domains 2"
                     /db_xref="GeneID:307106"
                     /db_xref="RGD:1305027"
     exon            1..99
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            100..231
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..2807
                     /gene="Sfmbt2"
                     /codon_start=1
                     /product="scm-like with four MBT domains protein 2"
                     /protein_id="NP_001100834.2"
                     /db_xref="GeneID:307106"
                     /db_xref="RGD:1305027"
                     /translation="MERRLPVLKIRTSSSSLERITSPENGNGSLDTEEDSRQEETEFS
                     WGDYLDETGARAVPHVCFRHVEISIQSNFQPGMKLEVANKNHPDTYWVATIITTCGQL
                     LLLRYCGYGEDRRADFWCDVIIADLHPVGWCTQNNKVLRPPDAIKEKYADWEEFLIHE
                     LTGSRTAPASLLEGPLRGKGPIDLITVDSLIELQDSQNPFQYWIVSVIENVGGRLRLR
                     YVGLEHTESYDRWLFYLDYRLRPIGWCQEKKYRMDPPSELYYLKLPFEWKCALEKALL
                     AAAECPLPMEVFKDHADLGSHFFTVGMRLETLHINDPFHIYPATVTKVFNSQFFQVAI
                     DDLRAETNGLTMLCHADSLGILPVQWCLKNGVNLAPPKGYSGQDFNWVDYHKQREAEG
                     APPYCFKNTFARGFAKNMKLEAVNPKNPGEVCVATVISVRGSLLWLRLEGVETPMPEI
                     IVDIDSMDIFPVGWCEANSYPLTTPYKSSSKSKKKPITVPPEKPSLPPVPVENIPQEL
                     CLPPQTDTAAGAANEKYYCPQLFVNHRCFSGPFLNKGRISELPQSVGPGKCVLVLKEI
                     LTMITNAAYKPGRVLRELQLVEDPEWDFQEEVLKAKYRGKIYRAVVKIVRTADQVTSF
                     CQQVCAKLECCPNLFSPLLISENCPENCSIRTKTKYTYYYGKRKRIIKPPLGESNTES
                     APKPTRRRKRRKSIYVQKKRKSSAVAMPATSAQETEEDDPEALDTASEETGYVVQNYK
                     TQHVPVEMPFTRSQRAMILRKHSGAVKHPPVERARRVRSVHSTASSNNRNKVPLVRIE
                     KSEDPRQSEEEKLILESNPLEWSVTDVVRFIKLTDCAPLARIFQEQDIDGQALLLLTL
                     PTVQECMELKLGPAIKLCHQIERVKVAFYAQYAN"
     exon            232..326
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            327..567
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            568..656
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            657..903
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1001
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1103
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1251
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1334
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1458
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1459..1572
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1615
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1686
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1829
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1830..1939
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2115
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            2116..2279
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            2280..2537
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2666
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
     exon            2667..5756
                     /gene="Sfmbt2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtctggaat tccaactgca agttcctgca aggtttcctg ctaagcacca ggtcgctttg
       61 acagaggaca tccatctctg aagatcccga gaggagtttg atgaattaag ggagctcgag
      121 gcatagtcaa cagcatggag agacgtttgc cagttttgaa gatccgcacc tcatcctcct
      181 ctctggaaag gattaccagc ccagaaaatg ggaatgggag tcttgacaca gaggaagatt
      241 ccaggcagga ggaaactgag ttcagctggg gagactattt ggatgagacg ggtgccagag
      301 cggtaccaca cgtgtgcttc agacatgtgg agatcagcat tcagagtaac ttccagccag
      361 gaatgaagtt ggaggtggcc aacaagaacc atccagacac ttactgggtg gccacgatca
      421 tcaccacctg tggacagctg ctgctcctgc gttactgtgg ttatggggag gaccgaaggg
      481 ctgacttctg gtgtgatgtc atcatagcag atctgcaccc tgtggggtgg tgtactcaga
      541 acaacaaggt gttgaggccc ccggatgcta tcaaagagaa gtatgccgac tgggaggaat
      601 tcctcataca tgaattgact ggttctcgga cagcacctgc aagccttctg gaaggtcctc
      661 tgcgagggaa aggcccaata gacctcatta cagttgattc cttaatagag ctgcaggact
      721 ctcagaatcc ctttcagtac tggatagtta gtgtgattga aaatgtcgga ggaagattac
      781 gccttcgcta tgtgggattg gagcacactg aatcctatga ccggtggtta ttttacttgg
      841 attacagact tcgaccaatt ggttggtgtc aagaaaaaaa atacagaatg gatccacctt
      901 cagaacttta ttatctgaag ttgccttttg aatggaaatg tgcactagaa aaagccttgc
      961 ttgccgctgc agagtgtccc cttccaatgg aagtatttaa ggaccatgca gacttgggaa
     1021 gccatttctt tacagttggg atgcggctgg agacattgca catcaatgat ccctttcata
     1081 tctatcctgc aacagtgacc aaggttttta acagtcagtt tttccaagtg gccattgatg
     1141 acttaagagc cgagactaat ggactcacaa tgctgtgcca cgcagattct ttggggattt
     1201 tgccagtaca gtggtgcctt aaaaatggag tcaacctcgc tcctcccaaa ggttactcag
     1261 gccaggattt taactgggtg gattatcaca agcagcgcga ggccgaagga gcccctcctt
     1321 actgcttcaa aaatacattt gctcggggct ttgcaaagaa catgaagctt gaagctgtga
     1381 accccaagaa tccaggagag gtgtgcgtgg ccactgtgat cagcgtgaga gggagtttgt
     1441 tatggctccg tttagaaggt gtggagacac cgatgccaga gatcattgtg gatatagatt
     1501 ccatggacat cttccccgta ggctggtgtg aagcgaattc ttaccctttg accacaccat
     1561 acaagtcgtc ctcaaaaagc aagaaaaaac cgatcactgt acctccggaa aaaccatcgt
     1621 tacccccagt gcctgttgag aatatacctc aagagctttg cctgccccct cagacggaca
     1681 ccgcagcagg agccgccaat gagaagtact actgcccaca gctgttcgtc aaccaccggt
     1741 gtttctcagg cccgttcctg aacaaaggaa ggatttcaga actacctcag tccgtgggac
     1801 ctggcaagtg cgtgctggtg cttaaagaga ttcttaccat gattaccaat gcagcctaca
     1861 agcccgggag ggtgttgaga gagttacagc tggtagaaga tccagagtgg gatttccagg
     1921 aggaggtgct caaggcaaaa taccgaggca aaatatacag ggccgtggtc aagatcgtgc
     1981 ggacagcaga ccaagtaaca agcttctgcc agcaagtttg tgccaaactg gagtgctgtc
     2041 cgaacttatt cagtcccctg ctgatctctg aaaactgccc ggagaattgt tccatccgca
     2101 ccaaaaccaa atacacctat tactatggga aaaggaagag gatcattaaa cctccactcg
     2161 gagaaagcaa cactgaaagc gcaccaaaac ccaccaggag aaggaaacga agaaaatcaa
     2221 tctatgtgca gaagaaacgg aaatcctctg cggtggccat gccagcgacc tcggcacagg
     2281 aaactgaaga ggacgatcca gaggccctgg acactgcaag cgaggaaact ggttacgtgg
     2341 tccagaatta caagacacag catgtaccag tagagatgcc ctttacccgt tcacagaggg
     2401 ctatgatcct gaggaaacat tcaggggctg taaagcaccc tccagtggaa agggcacgga
     2461 gggtccgctc agtgcactct actgcctctt ctaataacag aaacaaggtt ccacttgtca
     2521 ggattgagaa atcagaggac ccaaggcagt cggaggagga gaaactgatt cttgagagca
     2581 atccgctgga gtggtccgtc acagatgtgg tgcgattcat taagctgact gactgtgcac
     2641 ctttggccag gatctttcaa gagcaggaca tcgatggcca ggctctcctc ctgctcactc
     2701 tcccaacagt gcaggagtgc atggagctga agctaggacc tgcgatcaaa ttatgccatc
     2761 agatcgagag agtgaaagtg gctttctacg cccagtacgc caattagctc acccttcccg
     2821 agtgggcatc gcctgattct gattatgctg tgtttgttgt aaaggttttc aggaccgagg
     2881 ccttgatttc ctgggctttg tgaaatggca caatccattg ggggtctcca aaaagccaga
     2941 agcccaggac ctctttcttg caccagccta tttggtagtc ctatgttttt aaagcacacg
     3001 gaaggaacac cagcagtgta ttgtgaacgt tctgagacag accttccctg gctcagggcc
     3061 tccgattccc tttttttctc ccactcaaag caggtagttt tatggaagtc aggtctcctt
     3121 acactgaggt ctaggttcct gggaaactca gatggattag gtgtatccta gcagaacccc
     3181 cgtctagctg ccatttttgc ctgactcagc ctcaagctct cttacagctc tgtctgacgc
     3241 acacacgcac gcacgctacc gtggtttaga gtcacctcct attccatttg gtctcactta
     3301 agctccattc tcccatacaa ctctggactc cattcagctc cgtcctctgt cagaggtgcc
     3361 ttttcacaag tatggcagct tgccacgagc ccgctaccgt gtaagcaaag cctagaacac
     3421 tctatgtagt ctcctccaga accatagctt caatgtttta agatcactgt gacccatcag
     3481 gaggaggctg ctttagggaa gttatcaaat tctgtattga agaaacattt tcagggagca
     3541 agtataggaa aagactttgg ggacagtgct tctcgtgagc tagctgtatc cacttagaat
     3601 gttaacacag atggttgcta caagcaaacc cctccgagcc tctcttccgc tagtgcctag
     3661 cttgccacat ggaaaggaat cccaggggag caacataaga tagcagagca aatactggat
     3721 ctggatccag tgggtttcca tccattgtct agtggccaac ttcatgtcct tgggtaactt
     3781 gccaccaccc tggaccccaa gttcccattg agaagtaagg tagacattca ctagagaggc
     3841 actgagggca cctttcccct gctcccgcta gagaggagtc taggtagacc ataatgagag
     3901 aaagaatgtg gcctcagagt ttaaccctcc atcttctgcc tttcactctc ttttggggtt
     3961 gcttgtgaaa tgtcatctgt agcctaatca gtgattataa aatctggctg ataccagcac
     4021 tcacctgtat tttcctgtga tcttgcaaac ccaaaggagc tgaggcacat tataacgtgg
     4081 aggtcacctc catgtctttt ggaaaccagg cagggaaacc agcctttcat tctgcttagg
     4141 agtgcctcac tttggaagct taacttccca cctatccggg ccttactggt ttactttgtg
     4201 gtttcccata gttttttcat aatcacattt ccttcatctg ttgtccttga ctagaaccac
     4261 aactgtccca gagcatggga tgacagctga tagctgcttg tcctttggct gaggtttaag
     4321 gcagggtagc ccatcagccc gtgaaagctc tggttgccta tgttaggcac ccattctcgg
     4381 cacggtcatg gttgcaggtg gaattggaaa gcgaattgtg tgtggctgag acactttagt
     4441 cttccctgaa gctggttctc tacgtcaagc ctgtaggccg ttggcaaatg ggtgtgccta
     4501 gggacaagtg gtgttggact gtgtcctctg gagctgtaag gatggagcca ctcctgtcgg
     4561 tgtctgtgtg gttgccttgc agttagattt ctctcttcta aactacatgt tgaaccttcc
     4621 ttgcttcatc tgccttctca gccacacact tttggccata aatactcagt ctaccggttg
     4681 gaaagggtat ctatttcaag atgggggggt gacatttctc ctgtatcgac tccttgattc
     4741 ttcactgtgg tcttttcaag ctgagctatt tcttttgcat ctgaaatggg atgtggctat
     4801 ggcatcgcta gaacacgatt tgctttcaga acaaatgtca ctttctcatg ccatttcccg
     4861 taatgacaca gaggaggagg cgttgcccca taacatgagg atttcctaga ggtctcctga
     4921 gcccacagaa agccagaaaa gcactgacag aaaagtctgt caggacatgt ccaccattgg
     4981 tcagaaaccc ttcttctgtg gatccaaatg ttccagcccc tctccatgct tcagccttgc
     5041 agtttagcgt tggtcttcct ctgcagtgtc agctccccca gccttgcttt ggcaaggaag
     5101 aggtgacagt aatcttacca ggggctactc tcatcatagt ggctgtcaac ccgcaagcca
     5161 tccccccaac ccccgtgaga cttgagaagt atcttgatga ccaaagagga tgatttttct
     5221 cagagaaagg tgccagtgtc gtcctccgga gctttgatcc aggatggtgt gctcacgtgc
     5281 gcaatgcaat tttgtcacca gattgtaatg tgggttttgt ctctctctac ccttgcctct
     5341 cactgtgttt gtctgagtca cagaactgat ttccactgtg tttgtctgaa tcacaaagct
     5401 gatttccaag gattgattgg gaagaaatag atggattttt atacacgtac accaaaaata
     5461 ttctgcccta agtaccatgg aatgatgccc ttgcctcatt acttccttgt tggtatcatt
     5521 tccttatctc tttgattatc ttctgggacc agtgtccgct cctccaagca cccacccttt
     5581 gggtgcatca ctccattcat ggcatgacca gtccatgcca tatgactgag gagtggaagt
     5641 gccacctcaa cttcagtgat gacagtctgt catttatgcc caccttaaaa tgtagggagc
     5701 ttgtttcagc ccccaatttc tggagtatat ttgttctgtg ttatataaaa aaaaaa
//
