LOCUS       NM_001271222             711 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus splicing factor 3B, subunit 6 (Sf3b6), mRNA.
ACCESSION   NM_001271222 XM_002726721 XM_003750128
VERSION     NM_001271222.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 711)
  AUTHORS   Teng T, Tsai JH, Puyang X, Seiler M, Peng S, Prajapati S, Aird D,
            Buonamici S, Caleb B, Chan B, Corson L, Feala J, Fekkes P, Gerard
            B, Karr C, Korpal M, Liu X, T Lowe J, Mizui Y, Palacino J, Park E,
            Smith PG, Subramanian V, Wu ZJ, Zou J, Yu L, Chicas A, Warmuth M,
            Larsen N and Zhu P.
  TITLE     Splicing modulators act at the branch point adenosine binding
            pocket defined by the PHF5A-SF3b complex
  JOURNAL   Nat Commun 8, 15522 (2017)
   PUBMED   28541300
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 711)
  AUTHORS   Cui W, Dai X, Marcho C, Han Z, Zhang K, Tremblay KD and Mager J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 711)
  AUTHORS   Cretu C, Schmitzova J, Ponce-Salvatierra A, Dybkov O, De Laurentiis
            EI, Sharma K, Will CL, Urlaub H, Luhrmann R and Pena V.
  TITLE     Molecular Architecture of SF3b and Structural Consequences of Its
            Cancer-Related Mutations
  JOURNAL   Mol Cell 64 (2), 307-319 (2016)
   PUBMED   27720643
REFERENCE   4  (bases 1 to 711)
  AUTHORS   Maserati M, Dai X, Walentuk M and Mager J.
  TITLE     Identification of four genes required for mammalian blastocyst
            formation
  JOURNAL   Zygote 22 (3), 331-339 (2014)
   PUBMED   23211737
REFERENCE   5  (bases 1 to 711)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   6  (bases 1 to 711)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   7  (bases 1 to 711)
  AUTHORS   Chen YI, Moore RE, Ge HY, Young MK, Lee TD and Stevens SW.
  TITLE     Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes
            expands the catalog of participating factors
  JOURNAL   Nucleic Acids Res 35 (12), 3928-3944 (2007)
   PUBMED   17537823
REFERENCE   8  (bases 1 to 711)
  AUTHORS   Schellenberg MJ, Edwards RA, Ritchie DB, Kent OA, Golas MM, Stark
            H, Luhrmann R, Glover JN and MacMillan AM.
  TITLE     Crystal structure of a core spliceosomal protein interface
  JOURNAL   Proc Natl Acad Sci U S A 103 (5), 1266-1271 (2006)
   PUBMED   16432215
REFERENCE   9  (bases 1 to 711)
  AUTHORS   Will CL, Schneider C, Hossbach M, Urlaub H, Rauhut R, Elbashir S,
            Tuschl T and Luhrmann R.
  TITLE     The human 18S U11/U12 snRNP contains a set of novel proteins not
            found in the U2-dependent spliceosome
  JOURNAL   RNA 10 (6), 929-941 (2004)
   PUBMED   15146077
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM108041.1, FM089942.1 and FM109760.1.
            
            On or before Sep 9, 2012 this sequence version replaced
            XM_003750128.1, XM_002726721.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-363               FM108041.1         1-363
            364-680             FM089942.1         329-645
            681-711             FM109760.1         633-663
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q14"
     gene            1..711
                     /gene="Sf3b6"
                     /note="splicing factor 3B, subunit 6"
                     /db_xref="GeneID:100365504"
                     /db_xref="RGD:2318878"
     exon            1..288
                     /gene="Sf3b6"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..636
                     /gene="Sf3b6"
                     /note="splicing factor 3B, 14 kDa subunit-like"
                     /codon_start=1
                     /product="splicing factor 3B subunit 6"
                     /protein_id="NP_001258151.1"
                     /db_xref="GeneID:100365504"
                     /db_xref="RGD:2318878"
                     /translation="MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGP
                     IRQIRVGNTPETRGTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMD
                     TKKKEEQLKLLKEKYGINTDPPK"
     exon            289..407
                     /gene="Sf3b6"
                     /inference="alignment:Splign:2.1.0"
     exon            408..546
                     /gene="Sf3b6"
                     /inference="alignment:Splign:2.1.0"
     exon            547..711
                     /gene="Sf3b6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtatccggaa gcgtcttaga gctcgctttt tcgccttccg gactgacaac gcgttctctc
       61 taatttgact tggagcatct tttctaggaa gtaaacacgt cctagtttga gacgcggacc
      121 ttccggcagt gccgtaacag cttccggctt tacctggctg taaatatcct gtatgtggcg
      181 ccgtgtcgcc cacgaaggcg actgagtttt tagaaatacc cagaaggatc ttacggtaac
      241 ctacatcggc ccgccaagat ggcgatgcaa gcggctaaga gggcgaatat ccgcctccca
      301 cctgaagtaa atcggatttt gtatataagg aatttgccat acaaaatcac agcagaagaa
      361 atgtatgata tatttgggaa atatggacct attcgtcaaa tcagagtagg aaatacacct
      421 gaaaccagag gaacagccta tgtggtctat gaagacatct ttgatgctaa gaatgcctgt
      481 gaccacctat caggattcaa cgtttgtaac agataccttg tggttttata ttacaatgct
      541 aaccgggcat tccagaagat ggacaccaag aagaaggagg agcagctgaa gcttctcaag
      601 gaaaagtatg gcatcaacac agatcccccc aaatgagtaa cagccatgtg tggtcttggt
      661 tacccttctc ttttttatta atactgaatg aatattgcaa tttcttattt g
//
