LOCUS       NM_001126092             713 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus splicing factor 3b, subunit 5 (Sf3b5), mRNA.
ACCESSION   NM_001126092 XM_001059359
VERSION     NM_001126092.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Zhang,X., Yan,C., Zhan,X., Li,L., Lei,J. and Shi,Y.
  TITLE     Structure of the human activated spliceosome in three
            conformational states
  JOURNAL   Cell Res 28 (3), 307-322 (2018)
   PUBMED   29360106
REFERENCE   2  (bases 1 to 713)
  AUTHORS   Bertram,K., Agafonov,D.E., Dybkov,O., Haselbach,D., Leelaram,M.N.,
            Will,C.L., Urlaub,H., Kastner,B., Luhrmann,R. and Stark,H.
  TITLE     Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for
            Activation
  JOURNAL   Cell 170 (4), 701-713 (2017)
   PUBMED   28781166
REFERENCE   3  (bases 1 to 713)
  AUTHORS   Teng,T., Tsai,J.H., Puyang,X., Seiler,M., Peng,S., Prajapati,S.,
            Aird,D., Buonamici,S., Caleb,B., Chan,B., Corson,L., Feala,J.,
            Fekkes,P., Gerard,B., Karr,C., Korpal,M., Liu,X., T Lowe,J.,
            Mizui,Y., Palacino,J., Park,E., Smith,P.G., Subramanian,V.,
            Wu,Z.J., Zou,J., Yu,L., Chicas,A., Warmuth,M., Larsen,N. and Zhu,P.
  TITLE     Splicing modulators act at the branch point adenosine binding
            pocket defined by the PHF5A-SF3b complex
  JOURNAL   Nat Commun 8, 15522 (2017)
   PUBMED   28541300
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 713)
  AUTHORS   Cretu,C., Schmitzova,J., Ponce-Salvatierra,A., Dybkov,O., De
            Laurentiis,E.I., Sharma,K., Will,C.L., Urlaub,H., Luhrmann,R. and
            Pena,V.
  TITLE     Molecular Architecture of SF3b and Structural Consequences of Its
            Cancer-Related Mutations
  JOURNAL   Mol Cell 64 (2), 307-319 (2016)
   PUBMED   27720643
REFERENCE   5  (bases 1 to 713)
  AUTHORS   Chen,Y.I., Moore,R.E., Ge,H.Y., Young,M.K., Lee,T.D. and
            Stevens,S.W.
  TITLE     Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes
            expands the catalog of participating factors
  JOURNAL   Nucleic Acids Res 35 (12), 3928-3944 (2007)
   PUBMED   17537823
REFERENCE   6  (bases 1 to 713)
  AUTHORS   Will,C.L., Schneider,C., Hossbach,M., Urlaub,H., Rauhut,R.,
            Elbashir,S., Tuschl,T. and Luhrmann,R.
  TITLE     The human 18S U11/U12 snRNP contains a set of novel proteins not
            found in the U2-dependent spliceosome
  JOURNAL   RNA 10 (6), 929-941 (2004)
   PUBMED   15146077
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001126092.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: FQ217549.1, FQ221936.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-713               JAXUCZ010000001.1  9177189-9177901
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p13"
     gene            1..713
                     /gene="Sf3b5"
                     /note="splicing factor 3b, subunit 5"
                     /db_xref="GeneID:680891"
                     /db_xref="RGD:1586993"
     exon            1..713
                     /gene="Sf3b5"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..406
                     /gene="Sf3b5"
                     /codon_start=1
                     /product="splicing factor 3B subunit 5"
                     /protein_id="NP_001119564.1"
                     /db_xref="GeneID:680891"
                     /db_xref="RGD:1586993"
                     /translation="MTDRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYM
                     GHFDLLNYFAIAENESKARVRFNLMEKMLQPSGPPADKPEEN"
ORIGIN      
        1 actgcgtgtc gtctttctcc tgcgccagca cgaatagagc ttttgtgcgg cggcagcggc
       61 ggcggcgtct ctctgatttg aacgccgaac agcggtagct tctcatctgt ggcctgacct
      121 cgaagcctaa gaacagagcg gcgagatgac ggaccggtac accatccaca gccagctcga
      181 gcatctgcag tccaagtaca tcggcacggg ccacgccgac accaccaagt gggaatggct
      241 tgtgaaccag catcgggatt cctactgctc ctacatgggt cacttcgacc tcctcaacta
      301 cttcgccatt gctgagaatg agagcaaagc gcgcgtgcgt ttcaacctga tggagaaaat
      361 gctgcagccc agcgggccgc cggcggacaa gccggaggag aactgaggcg agcgcttccc
      421 agccttcccc atctgccatc tgtggaccga tcctcctgac tcctgcttct cgaccattct
      481 ccgttgggtg tatcgcctga cctgcttacc tgtggacggt tccgaacaag tcatcgagag
      541 actgtcgggt ctcctgggag ctgtgcggaa ggagtgatcc cagaatcggc aagcgaggga
      601 gaagactgcc tgggagtgat gacgcattcc gagtcagctt ttcgatagtt gatgtcgttc
      661 tcgccttttt tttttttaaa tatatatcat acataaagtt aggatttgtt ata
//
