LOCUS       NM_001113747            1725 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus SET domain containing 4 (Setd4), mRNA.
ACCESSION   NM_001113747 XM_001070821 XM_340970
VERSION     NM_001113747.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Ye S, Ding YF, Jia WH, Liu XL, Feng JY, Zhu Q, Cai SL, Yang YS, Lu
            QY, Huang XT, Yang JS, Jia SN, Ding GP, Wang YH, Zhou JJ, Chen YD
            and Yang WJ.
  TITLE     SET Domain-Containing Protein 4 Epigenetically Controls Breast
            Cancer Stem Cell Quiescence
  JOURNAL   Cancer Res 79 (18), 4729-4743 (2019)
   PUBMED   31308046
REFERENCE   2  (bases 1 to 1725)
  AUTHORS   Faria JA, Correa NC, de Andrade C, de Angelis Campos AC, Dos Santos
            Samuel de Almeida R, Rodrigues TS, de Goes AM, Gomes DA and Silva
            FP.
  TITLE     SET domain-containing Protein 4 (SETD4) is a Newly Identified
            Cytosolic and Nuclear Lysine Methyltransferase involved in Breast
            Cancer Cell Proliferation
  JOURNAL   J Cancer Sci Ther 5 (2), 58-65 (2013)
   PUBMED   24738023
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158669.1.
            
            On or before Jan 26, 2008 this sequence version replaced
            XM_340970.3, XM_001070821.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158669.1, SRR8487231.79444.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1725
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..1725
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /note="SET domain containing 4"
                     /db_xref="GeneID:245975"
                     /db_xref="RGD:619899"
     exon            1..198
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            199..361
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     CDS             295..1614
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /EC_number="2.1.1.364"
                     /note="hypothetical protein RDA279"
                     /codon_start=1
                     /product="SET domain-containing protein 4"
                     /protein_id="NP_001107219.1"
                     /db_xref="GeneID:245975"
                     /db_xref="RGD:619899"
                     /translation="MQRRRGRTERVRRRRRSSGSRGVNESCRSEFIELRKWLKERKFE
                     DTGLLVPACFPGTGRGLMSKASLQEGQVIISLPESCLLTTDTVIRSSVGPYIKKWKPP
                     VSPLLALCTFLVSERHAGSHSLWKSYLDILPKSYTCPVCLEPEVVDLLPGPLRAKAEE
                     QRARVQDLFASSRDFFSTLQPLFAESVDSIFSYHAFLWAWCTVNTRAVYLKSRRQECL
                     SSEPDTCALAPFLDLLNHSPHVQVKAAFNEKTRCYEIRTASRCRKHQEAFICYGPHDN
                     QRLLLEYGFVAFGNPHACVPVSGEMLLKYLPPADKQVHKKLSILEDHGFTGNLTFGWD
                     GPSWRLLTALKLLCLEAERFTSWKKVLIGDVISDRNEKASLGVAQKICSDFIAEIHSE
                     LRKVSDMKERKGSLISQLCLVEALRMEELRILQASAEILSSSLAPLS"
     exon            362..460
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            461..498
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            499..587
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            588..1017
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1192
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            1193..1274
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1355
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            1356..1479
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1700
                     /gene="Setd4"
                     /gene_synonym="Rda279"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtggagtgaa tgatatcggc ttggtcctgg gccgagaccc tgggccgctc tgtggcgtgc
       61 ggccatcact ggggtccggt ggcgagcagg ggacagggct gtagtggaac tgcgcgtcct
      121 cgtgtgccac tcgtgggctc ctgaacggac ttggtgtccc gctccagact gactcataaa
      181 gcaagtcttc ctgccgaggt gccaaggtct tcaattctta tccagctgga aagtgaggca
      241 gcttctcatt actctccgtt gagcgggaca caagaggctc cgtcctgggt tagcatgcag
      301 agacggagag gaagaacaga gagggtgagg aggcgacgtc gaagctctgg ctcaagagga
      361 gtgaatgaga gctgcagatc tgaatttata gagctaagaa aatggctgaa agagaggaag
      421 tttgaagata caggcttatt agtacctgcc tgctttccag gaacaggaag agggctgatg
      481 agcaaagcgt cgctgcagga gggccaggtg attatctcac tgcctgagag ctgtctgctc
      541 accacggaca ctgtgatccg aagctccgta gggccctaca ttaagaagtg gaagcctccg
      601 gtgtctcctc tgctggcttt gtgtaccttt ttggtctcag aaagacatgc aggcagtcat
      661 tccctctgga agtcttacct ggacatttta cccaagtcat atacctgccc ggtgtgcttg
      721 gagccagaag tggtggatct tcttccggga cctttgaggg cgaaggcgga agagcagaga
      781 gcccgcgtgc aggatttgtt tgcctcctct agagacttct tctctaccct gcagcctctg
      841 tttgcagagt ctgtggacag cattttcagc taccatgcct tcctctgggc ctggtgcaca
      901 gtgaacacca gagctgtgta cctgaagtct aggaggcagg agtgcctttc ctcagagccg
      961 gacacgtgtg cccttgctcc gttcctggat ctgctgaatc acagcccaca tgtccaggtg
     1021 aaagcagcat tcaacgagaa gaccaggtgc tatgagatta gaacagcctc tcgctgtagg
     1081 aagcaccagg aggcgttcat ctgctacggt ccccatgaca accagcggct gctcctggag
     1141 tatggctttg ttgcctttgg caatcctcac gcatgtgttc ctgtctcagg agagatgctg
     1201 ctcaagtacc tcccgccagc cgataagcag gtgcacaaga agctgtccat cttggaggat
     1261 catggcttca caggaaattt gacgtttgga tgggatggac catcttggag gttgctcaca
     1321 gctctcaagt tgttgtgtct ggaagccgag cggtttacgt cctggaagaa ggtgctcatt
     1381 ggtgacgtaa tctccgatag gaatgagaag gcaagcttgg gcgtggccca gaaaatatgc
     1441 tctgatttca ttgcggagat tcactccgag ctgcgcaagg tttctgacat gaaggaaagg
     1501 aaaggatcgc tgataagtca gctctgtttg gtggaagctt tgcggatgga agagctgcgg
     1561 attcttcagg cttctgctga gatcctgagt agttcgctgg cccccttgtc ctgagttctc
     1621 gggatcacgt ggcccctccc atggagggtg ctccagctgc attttcactg aggttggaat
     1681 aaatggatta tatgacatca aaaaaaaaaa aaaaaaaaaa aaaaa
//
